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3 studies found for:    TRPV4
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Rank Status Study
1 Recruiting A Study to Evaluate the Effect of the Transient Receptor Potential Vanilloid 4 (TRPV4) Channel Blocker, GSK2798745, on Pulmonary Gas Transfer and Respiration in Patients With Congestive Heart Failure
Condition: Heart Failure, Congestive
Interventions: Drug: GSK2798745;   Drug: Placebo
2 Completed A Method Validation Study for Evaluation of Novel Treatments Limiting Pulmonary Oedema in Cardiac Failure
Condition: Heart Failure, Congestive
Interventions: Procedure: DCE-MRI scans;   Other: Gadobutrol
3 Completed A First Time in Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of GSK2798745 in Healthy Subjects and Stable Heart Failure Patients
Condition: Oedema, Pulmonary
Interventions: Drug: GSK2798745 solution;   Drug: GSK2798745 suspension;   Drug: GSK2798745 capsule;   Drug: Placebo solution;   Drug: Placebo suspension;   Drug: Placebo capsule

Study has passed its completion date and status has not been verified in more than two years.