146 studies found for:    Spinal Muscular Atrophy
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Rank Status Study
21 Completed An Open-label Safety and Tolerability Study of ISIS SMNRx in Patients With Spinal Muscular Atrophy Who Previously Participated in ISIS 396443-CS1
Condition: Spinal Muscular Atrophy
Intervention: Drug: ISIS-SMNRx
22 Completed An Open-label Safety, Tolerability and Dose-range Finding Study of Multiple Doses of ISIS SMNRx in Patient With Spinal Muscular Atrophy
Condition: Spinal Muscular Atrophy
Intervention: Drug: ISIS-SMNRx
23 Active, not recruiting An Open-label Safety and Tolerability Study of IONIS SMNRx in Patients With Spinal Muscular Atrophy Who Previously Participated in IONIS SMNRx-CS2 or IONIS SMNRx-CS10
Condition: Spinal Muscular Atrophy
Intervention: Drug: IONIS-SMNRx
24 Completed Clinical Assessment of Spinal Muscular Atrophy Type II and III (SMA Europe)
Condition: Spinal Muscular Atrophy
Intervention: Other: Functional tests
25 Active, not recruiting Palliative Care in Spinal Muscular Atrophy (SMA) 1
Condition: Spinal Muscular Atrophy 1
Intervention: Other: Follow-up diary and questionnaire
26 Recruiting Prospective Evaluation of Infants With Spinal Muscular Atrophy:
Condition: Spinal Muscular Atrophy
Intervention:
27 Recruiting Safety and Efficacy Study of Pyridostigmine on Patients With Spinal Muscular Atrophy Type 3
Condition: Spinal Muscular Atrophy Type 3
Intervention: Drug: Pyridostigmine Bromide
28 Recruiting A Study of Multiple Doses of ISIS SMNRx (ISIS 396443) Delivered to Infants With Genetically Diagnosed and Presymptomatic Spinal Muscular Atrophy
Condition: Spinal Muscular Atrophy
Intervention: Drug: ISIS SMNRx (ISIS 396443)
29 Active, not recruiting Clinical Study of Spinal Muscular Atrophy
Condition: Spinal Muscular Atrophy
Intervention:
30 Active, not recruiting Gene Transfer Clinical Trial for Spinal Muscular Atrophy Type 1
Condition: Spinal Muscular Atrophy 1
Intervention: Biological: AVXS-101
31 Completed Study of Safety and Dosing Effect on SMN Levels of Valproic Acid (VPA) in Patients With Spinal Muscular Atrophy
Condition: Spinal Muscular Atrophy
Intervention: Drug: Valproic Acid
32 Completed Aerobic Training in Patients With Spinal Muscular Atrophy Type III
Condition: Spinal Muscular Atrophy
Intervention: Behavioral: Aerobic conditioning
33 Active, not recruiting
Has Results
Progressive Strength Training in Spinal Muscular Atrophy
Condition: Muscular Atrophy, Spinal
Intervention: Other: Progressive strength training
34 Enrolling by invitation An Open-Label Study (SHINE) for Patients With Spinal Muscular Atrophy (SMA) Who Participated in Studies With IONIS-SMNRx
Condition: Spinal Muscular Atrophy
Intervention: Drug: IONIS-SMN Rx
35 Completed Evaluation of the Muscle Strength and Motor Ability in Children With Spinal Muscle Atrophy(SMA) Treated With Valproic Acid
Condition: Spinal Muscular Atrophy
Intervention:
36 Active, not recruiting A Study to Assess the Safety and Tolerability of ISIS 396443 in Participants With Spinal Muscular Atrophy (SMA).
Condition: Spinal Muscular Atrophy
Interventions: Drug: ISIS 396443;   Procedure: Sham Procedure
37 Completed A Trial of Hydroxyurea in Spinal Muscular Atrophy
Condition: Spinal Muscular Atrophy
Intervention: Drug: Hydroxyurea
38 Recruiting A Study of CK-2127107 in Patients With Spinal Muscular Atrophy
Condition: Spinal Muscular Atrophy
Interventions: Drug: CK-2127107 150 mg;   Drug: Placebo;   Drug: CK-2127107 450 mg
39 Recruiting Valproate and Levocarnitine in Children With Spinal Muscular Atrophy
Condition: Spinal Muscular Atrophy
Interventions: Drug: Valproate, Levocarnitine;   Drug: Placebo
40 Not yet recruiting Study of Feasibility to Reliably Measure Functional Abilities' Changes in Nonambulant Neuromuscular Patients Without Trial Site Visiting
Conditions: Spinal Muscular Atrophy;   Neuromuscular Disorders
Intervention: Other: Direct current stimulation of cervical spinal cord

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Indicates status has not been verified in more than two years