27 studies found for:    Recurrent GBM | Immunotherapy
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Rank Status Study
1 Active, not recruiting Vaccine Therapy in Treating Patients Undergoing Surgery for Recurrent Glioblastoma Multiforme
Condition: Recurrent Central Nervous System Neoplasm
Intervention: Biological: BTSC mRNA-loaded DCs
2 Recruiting Phase 2 Study of MEDI4736 in Patients With Glioblastoma
Condition: Glioblastoma
Interventions: Drug: MEDI4736;   Radiation: Radiotherapy;   Biological: Bevacizumab
3 Active, not recruiting DNX-2401 With Interferon Gamma (IFN-γ) for Recurrent Glioblastoma or Gliosarcoma Brain Tumors
Conditions: Glioblastoma;   Gliosarcoma
Interventions: Drug: Single intratumoral injection of DNX-2401;   Drug: interferon gamma
4 Recruiting Phase I Study of a Dendritic Cell Vaccine for Patients With Either Newly Diagnosed or Recurrent Glioblastoma
Conditions: Glioblastoma;   Glioblastoma Multiforme;   Glioma;   Astrocytoma;   Brain Tumor
Interventions: Biological: Dendritic cell vaccination, in addition to standard temozolomide chemotherapy and involved field radiation therapy;   Biological: Dendritic cell vaccination, with optional bevacizumab treatment for patients previously treated with bevacizumab
5 Completed Phase I Study of Cellular Immunotherapy for Recurrent/Refractory Malignant Glioma Using Intratumoral Infusions of GRm13Z40-2, An Allogeneic CD8+ Cytolitic T-Cell Line Genetically Modified to Express the IL 13-Zetakine and HyTK and to be Resistant to Glucocorticoids, in Combination With Interleukin-2
Conditions: Anaplastic Astrocytoma;   Anaplastic Ependymoma;   Anaplastic Meningioma;   Anaplastic Oligodendroglioma;   Brain Stem Glioma;   Ependymoblastoma;   Giant Cell Glioblastoma;   Glioblastoma;   Gliosarcoma;   Grade III Meningioma;   Meningeal Hemangiopericytoma;   Mixed Glioma;   Pineal Gland Astrocytoma;   Brain Tumor
Interventions: Biological: therapeutic allogeneic lymphocytes;   Biological: aldesleukin;   Other: laboratory biomarker analysis;   Procedure: positron emission tomography
6 Active, not recruiting Cellular Immunotherapy Study for Brain Cancer
Conditions: Gliomas;   Anaplastic Astrocytoma;   Anaplastic Oligodendroglioma;   Anaplastic Mixed Glioma;   Glioblastoma Multiforme;   Malignant Meningioma
Intervention: Drug: alloreactive CTL
7 Recruiting Safety and Efficacy Study of SL-701, a Glioma-Associated Antigen Vaccine To Treat Recurrent Glioblastoma Multiforme
Conditions: Adult Brain Glioblastoma;   Glioblastoma Multiforme
Interventions: Biological: SL-701; poly-ICLC (polyinosinic-polycytidylic acid stabilized with polylysine and carboxymethyl cellulose);   Drug: Bevacizumab
8 Recruiting A Study of ICT-121 Dendritic Cell Vaccine in Recurrent Glioblastoma
Condition: Glioblastoma Multiforme
Intervention: Biological: ICT-121 DC vaccine
9 Completed A Phase I Trial of Vorinostat in Combination With Bevacizumab & Irinotecan in Recurrent Glioblastoma
Condition: Glioblastoma
Interventions: Drug: Vorinostat;   Drug: Bevacizumab;   Drug: Irinotecan
10 Recruiting Photodynamic Therapy (PDT) For Recurrent High Grade Gliomas
Condition: Brain Tumor, Recurrent
Intervention: Drug: Photofrin photodynamic therapy.
11 Unknown  Study To Test the Safety and Efficacy of TVI-Brain-1 As A Treatment for Recurrent Grade IV Glioma
Conditions: Grade IV Glioma;   Grade IV Astrocytoma;   Glioblastoma Multiforme
Intervention: Biological: TVI-Brain-1
12 Completed Comparison of TransMID vs Standard Treatment of Cancerous Brain Tumors
Condition: Glioblastoma
Intervention: Drug: TransMID
13 Completed Cellular Adoptive Immunotherapy Using Genetically Modified T-Lymphocytes in Treating Patients With Recurrent or Refractory High-Grade Malignant Glioma
Condition: Brain and Central Nervous System Tumors
Interventions: Biological: therapeutic autologous lymphocytes;   Genetic: gene expression analysis;   Other: laboratory biomarker analysis
14 Completed Phase I/II Study To Test The Safety and Efficacy of TVI-Brain-1 As A Treatment For Recurrent Grade IV Glioma
Conditions: Glioma;   High Grade Astrocytoma;   Glioblastoma Multiforme
Intervention: Biological: Cancer vaccine plus immune adjuvant, plus activated white blood cells
15 Terminated Erlotinib Hydrochloride and Isotretinoin in Treating Patients With Recurrent Malignant Glioma
Conditions: Adult Anaplastic Astrocytoma;   Adult Anaplastic Oligodendroglioma;   Adult Diffuse Astrocytoma;   Adult Giant Cell Glioblastoma;   Adult Glioblastoma;   Adult Gliosarcoma;   Adult Mixed Glioma;   Adult Oligodendroglioma;   Recurrent Adult Brain Tumor
Interventions: Drug: erlotinib hydrochloride;   Drug: isotretinoin;   Other: laboratory biomarker analysis;   Genetic: protein expression analysis
16 Enrolling by invitation Proteome-based Personalized Immunotherapy of Glioblastoma
Condition: Glioblastoma
Interventions: Biological: Dendritic vaccine, allogeneic hematopoietic stem cells, cytotoxic lymphocytes;   Biological: Dendritic vaccine, autologous hematopoietic stem cells, cytotoxic lymphocytes
17 Completed Phase IIb Clinical Trial With TGF-β2 Antisense Compound AP 12009 for Recurrent or Refractory High-grade Glioma
Conditions: Glioblastoma;   Anaplastic Astrocytoma
Interventions: Drug: AP 12009 10 µM;   Drug: AP 12009 80 µM;   Drug: temozolomide or PCV;   Device: Drug delivery system for administration of AP 12009;   Procedure: Placement of Drug Delivery System
18 Completed Tumor Lysate Pulsed Dendritic Cell Immunotherapy for Patients With Brain Tumors
Condition: Glioblastoma
Interventions: Biological: Dendritic Cell Immunotherapy;   Biological: Dendritic Cell Vaccine
19 Recruiting A Phase I Study of AdV-tk + Prodrug Therapy in Combination With Radiation Therapy for Pediatric Brain Tumors
Conditions: Malignant Glioma;   Recurrent Ependymoma
Interventions: Biological: AdV-tk;   Drug: valacyclovir;   Radiation: Radiation
20 Active, not recruiting Vaccine Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
Condition: Malignant Neoplasms of Brain
Interventions: Biological: tetanus toxoid;   Biological: therapeutic autologous dendritic cells;   Biological: therapeutic autologous lymphocytes

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Indicates status has not been verified in more than two years