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70 studies found for:    Pulmonary Hypertension | Open Studies | NIH, U.S. Fed
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Pulmonary Hypertension | Open Studies | NIH, U.S. Fed (70 records)
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Rank Status Study
1 Recruiting Secondary Pulmonary Hypertension in Adults With Sickle Cell Anemia
Conditions: Pulmonary Hypertension;   Sickle Cell Anemia;   Sickle Cell Disease
Intervention:
2 Recruiting Tadalafil for Pulmonary Hypertension Due to Chronic Lung Disease
Conditions: Pulmonary Hypertension;   Chronic Obstructive Pulmonary Disease (COPD)
Interventions: Drug: Tadalafil;   Drug: placebo
3 Recruiting Pediatric Pulmonary Hypertension Network (PPHNet) Informatics Registry
Conditions: Pulmonary Vascular Disease;   Pulmonary Arterial Hypertension
Intervention:
4 Recruiting Improving Treatment Personalization of Pulmonary Hypertension Associated With Diastolic Heart Failure
Conditions: Pulmonary Hypertension;   Diastolic Heart Failure;   Heart Failure With Preserved Ejection Fraction
Intervention: Drug: Nebivolol
5 Unknown  Pharmacogenomics in Pulmonary Arterial Hypertension
Conditions: Pulmonary Arterial Hypertension;   Pulmonary Hypertension;   PAH WHO Group I
Interventions: Drug: Sitaxsentan;   Drug: Bosentan, Ambrisentan
6 Recruiting Effects of Spironolactone on Collagen Metabolism in Patients With Pulmonary Arterial Hypertension
Condition: Pulmonary Hypertension
Interventions: Drug: Spironolactone;   Drug: Placebo
7 Recruiting Spironolactone for Pulmonary Arterial Hypertension
Condition: Pulmonary Arterial Hypertension
Interventions: Drug: Spironolactone;   Drug: Placebo
8 Recruiting Pharmacokinetics of Sildenafil in Premature Infants
Condition: Persistent Pulmonary Hypertension of the Newborn
Intervention: Drug: 1 dose of sildenafil
9 Recruiting Natural History Study of Biomarkers in Pulmonary Arterial Hypertension
Conditions: Pulmonary Disease;   Pulmonary Hypertension
Intervention:
10 Recruiting Natural History of Sickle Cell Disease and Other Hemolytic Disorders
Conditions: Hemoglobin SC Disease;   Hematologic Diseases;   Sickle Cell Anemia;   Hemolytic Anemia
Intervention:
11 Recruiting Real-time MRI Right Heart Catheterization Using Passive Catheters
Conditions: Caridovascular Disease;   Congenital Heart Disease;   Pulmonary Hypertension
Interventions: Device: Balloon catheter for right heart catheterization;   Drug: Gadopentate Dimeglumine (Gadolinium); Contrast Agent;   Procedure: Right Heart Catheterization;   Procedure: Cardiac Real-time MRI;   Procedure: Vascular Hemostasis
12 Recruiting The NIH Exercise Therapy for Advanced Lung Disease Trials: Response and Adaptation to Aerobic Exercise in Patients With Interstitial Lung Disease
Conditions: Interstitial Lung Disease;   Idiopathic Pulmonary Fibrosis;   Interstitial Pneumonitis;   Desquamative Interstitial Pneumonia
Interventions: Other: Aerobic Exercise Training;   Other: Education
13 Recruiting Diaphragmatic Hernia Research & Exploration, Advancing Molecular Science
Condition: Congenital Diaphragmatic Hernia
Intervention:
14 Recruiting Atorvastatin for Microvascular Endothelial Function and Raynaud in Early Diffuse Scleroderma
Condition: Scleroderma
Interventions: Drug: atorvastatin;   Drug: Placebo
15 Recruiting Rituximab for Treatment of Systemic Sclerosis-Associated Pulmonary Arterial Hypertension (SSc-PAH)
Condition: Systemic Sclerosis-Associated Pulmonary Arterial Hypertension
Interventions: Biological: Rituximab;   Other: Placebo
16 Unknown  Pilot Study of the Safety and Efficacy of Carvedilol in Pulmonary Arterial Hypertension
Condition: Pulmonary Arterial Hypertension
Intervention: Drug: Carvedilol
17 Recruiting Inflammation, Viral Replication, and Atherosclerosis in Treated HIV Infection
Condition: Atherosclerosis
Intervention:
18 Recruiting Anti-Angiogenic Preeclampsia Milieu Impairs Infant Lung and Vascular Development
Condition: Preeclampsia
Intervention: Other: Diffusion Lung Capacity (DLCO), Vascular Challenge, Video Imaging, Specimen Collections
19 Recruiting Ugandan Non-Communicable Diseases and Aging Cohort
Conditions: HIV;   Cardiovascular Disease;   Chronic Obstructive Pulmonary Disease;   Atherosclerosis;   Hypertension;   Diabetes Mellitus
Intervention: Other: This is an observational study only
20 Recruiting Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care
Conditions: Infection;   Hypertension;   Pain;   Reflux;   Edema;   Hyperlipidemia;   Hypotension;   Hypercholesterolemia;   Sedation;   Anxiolysis;   Benzodiazepine Withdrawal;   Bipolar Disorder;   Autistic Disorder;   Schizophrenia;   Influenza Treatment or Prophylaxis;   Acute Decompensated Heart Failure;   Stable Angina;   Life-threatening Fungal Infections;   Nosocomial Pneumonia;   Community Acquired Pneumonia;   Acute Bacterial Exacerbation of Chronic Bronchitis;   Complicated Skin and Skin Structure Infections;   Uncomplicated Skin and Skin Structure Infections;   Chronic Bacterial Prostatitis;   Complicated Urinary Tract Infections;   Acute Pyelonephritis;   Uncomplicated Urinary Tract Infections;   Inhalational Anthrax (Post-Exposure);   Infantile Hemangioma;   Withdrawal;   Inflammation;   Bacterial Septicemia;   Cytomegalovirus Retinitis;   Herpes Simplex Virus;   Adenovirus;   Brain Swelling;   Airway Swelling;   Adrenal Insufficiency;   Anxiety;   Nausea;   Vomiting;   Convulsions;   Muscle Spasms;   Seizures;   Epilepsy;   Bartonellosis;   Brucellosis;   Cholera;   Plague;   Psittacosis;   Q Fever;   Relapsing Fever;   Rocky Mountain Spotted Fever;   Trachoma;   Tularemia;   Typhus Fever;   Bronchospasm;   Cardiac Arrest;   Hypersensitivity Reaction;   Cyanide Poisoning;   Acute Bacterial Sinusitis;   Bacterial Meningitis;   Sepsis;   Gastroparesis;   Opioid Addiction;   Migraines;   Headaches
Intervention: Drug: The POPS study is collecting PK data on children prescribed the following drugs of interest per standard of care:

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