58 studies found for:    Progressive Supranuclear Palsy
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21 Recruiting Biomarkers in Parkinsonian Syndromes
Conditions: Parkinsonian Syndromes;   Parkinson's Disease;   Multiple System Atrophy;   Progressive Supranuclear Palsy
Interventions: Other: CSF, blood and urine sampling;   Other: clinical measures of disease severity and progression
22 Completed Continuously Infused Recombinant-Methionyl Human Glial Cell Line-Derived Neurotrophic Factor (GDNF) to Treat Progressive Supranuclear Palsy
Condition: Progressive Supranuclear Palsy
Intervention: Drug: GDNF & Synchro Med Infusion System
23 Unknown  Clinical Trial to Evaluate Bone Marrow Stem Cell Therapy for PSP, a Rare Form of Parkinsonism
Condition: Progressive Supranuclear Palsy
Intervention: Biological: stem cell therapy
24 Recruiting A 6 Month, Open-Label, Pilot Futility Clinical Trial of Oral Salsalate for Progressive Supranuclear Palsy
Condition: Progressive Supranuclear Palsy
Intervention: Drug: Salsalate
25 Terminated Neuroprotection and Natural History in Parkinson's Plus Syndromes (NNIPPS)
Conditions: Multiple System Atrophy;   Progressive Supranuclear Palsy
Intervention: Drug: Riluzole
26 Recruiting Foot Mechanical Stimulation for Treatment of Gait and Gait Related Disorders in Parkinson's Disease and Progressive Supranuclear Palsy.
Conditions: Idiopathic Parkinson's Disease;   Progressive Supranuclear Palsy
Intervention: Device: Foot Mechanical Stimulation (GONDOLA)
27 Recruiting Safety Study of TPI-287 to Treat CBS and PSP
Conditions: Primary Four Repeat Tauopathies (4RT);   Corticobasal Syndrome (CBS);   Progressive Supranuclear Palsy (PSP);   Corticobasal Degeneration (CBD)
Interventions: Drug: TPI 287  2 mg/m2;   Drug: TPI-287 20 mg/m2;   Drug: Placebo;   Drug: TPI-287 6.3 mg/m2
28 Active, not recruiting Davunetide (AL-108) in Predicted Tauopathies - Pilot Study
Conditions: Predicted Tauopathies, Including:;   Progressive Supranuclear Palsy;   Frontotemporal Dementia With Parkinsonism Linked to Chromosome 17;   Corticobasal Degeneration Syndrome;   Progressive Nonfluent Aphasia
Interventions: Drug: davunetide (AL-108, NAP);   Drug: Placebo nasal spray
29 Recruiting Evaluation of [18F]MNI-777 PET as a Marker of Tau Pathology in Subjects With Tauopathies Compared to Healthy Subjects
Conditions: Alzheimer's Disease (AD);   Parkinson's Disease (PD);   Chronic Traumatic Encephalopathy (CTE);   Progressive Supranuclear Palsy (PSP);   Frontal Temporal Dementia (FTD);   Pick's Disease;   Tauopathies
Intervention: Drug: [18F]T807 ([18F]MNI-777)
30 Unknown  Efficacy Study for Treatment of Dementia in Progressive Supranuclear Palsy
Conditions: Progressive Supranuclear Palsy;   Dementia
Intervention: Drug: rivastigmine
31 Recruiting Identifying Biomarkers of Parkinson's Disease Using Magnetic Resonance Imaging (MRI)
Conditions: Parkinson's Disease (PD);   Parkinsonism;   Progressive Supranuclear Palsy (PSP);   Multiple System Atrophy (MSA)
Intervention:
32 Recruiting Advancing Research and Treatment for Frontotemporal Lobar Degeneration (ARTFL)
Conditions: FTLD;   Progressive Supranuclear Palsy (PSP);   Frontotemporal Dementia (FTD);   Corticobasal Degeneration (CBD);   PPA Syndrome;   Behavioral Variant Frontotemporal Dementia (bvFTD);   Semantic Variant Primary Progressive Aphasia (svPPA);   Nonfluent Variant Primary Progressive Aphasia (nfvPPA);   FTD With Amyotrophic Lateral Sclerosis (FTD/ALS);   Amyotrophic Lateral Sclerosis (ALS);   Oligosymptomatic PSP (oPSP);   Corticobasal Syndrome (CBS)
Intervention:
33 Recruiting Magnetic Resonance Imaging in the Diagnosis of Parkinsonian Syndromes
Conditions: Parkinson's Disease;   Multiple System Atrophy;   Progressive Supranuclear Palsy;   Vascular Parkinsonism
Intervention: Other: MRI exam of the brain
34 Recruiting 2-(1-{6-[(2-[F-18]Fluoroethyl) (Methyl)Amino]-2-naphthyl} Ethylidene) Malononitrile-PET for in Vivo Diagnose of Tauopathy in Unclassified Parkinsonism
Conditions: Progressive Supranuclear Palsy;   Multi-System Atrophy;   Parkinsonism
Intervention: Drug: [F18]-FDDNP
35 Recruiting MRI Study of Brain Activity in Healthy Adults and Individuals With Parkinsonism and Rapid Eye Movement Disorder.
Conditions: Movement Disorders (Incl Parkinsonism);   Tremor Familial Essential, 1;   REM Sleep Behavior Disorder
Intervention:
36 Unknown  Diagnostic and Prognostic Biomarkers in Parkinson Disease
Conditions: Parkinson Disease;   Multiple System Atrophy;   Progressive Supranuclear Palsy
Intervention:
37 Completed Effects of Coenzyme Q10 in PSP and CBD
Conditions: Progressive Supranuclear Palsy;   Neurological Disorders
Intervention: Drug: CoQ10
38 Completed Analysis of the Enteric Nervous System Using Colonic Biopsies
Conditions: Parkinson's Disease;   Multiple System Atrophy;   Progressive Supranuclear Palsy
Intervention: Procedure: colonoscopy or rectosigmoidoscopy
39 Completed Research of Biomarkers in Parkinson Disease
Conditions: Parkinson Disease;   Multiple System Atrophy;   Progressive Supranuclear Palsy;   Huntington Disease;   Dystonia;   Diffuse Lewy Body Disease
Intervention:
40 Recruiting Study of the Neural Basis of Analogical Reasoning
Conditions: Frontotemporal Dementia;   Progressive Supranuclear Palsy;   Healthy Subjects
Interventions: Device: transcranial magnetic stimulation;   Other: MRI imaging;   Other: EEG recording;   Behavioral: Neuropsychological examination

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Indicates status has not been verified in more than two years