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302 studies found for:    Primary Lateral Sclerosis
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Rank Status Study
1 Active, not recruiting Screening and Natural History: Primary Lateral Sclerosis and Related Disorders
Condition: Primary Lateral Sclerosis
Intervention:
2 Completed Nuclear Magnetic Spectroscopy Imaging to Evaluate Primary Lateral Sclerosis, Hereditary Spastic Paraplegia and Amyotrophic Lateral Sclerosis
Conditions: Primary Lateral Sclerosis;   Hereditary Spastic Paraplegia;   Amyotrophic Lateral Sclerosis
Intervention:
3 Completed Brain Function in Primary Lateral Sclerosis
Condition: Motor Neuron Disease
Intervention:
4 Completed Brain Function in Primary Lateral Sclerosis and Amyotrophic Lateral Sclerosis
Condition: Cerebral Cortex Dysfunction
Intervention:
5 Recruiting Use of Dalfampridin in Primary Lateral Sclerosis
Condition: Motor Neuron Disease, Upper
Intervention: Drug: dalfampridine
6 Completed Oxidative Stress in Motor Neuron Disease: COSMOS Add-On Study
Conditions: Motor Neuron Disease;   Primary Lateral Sclerosis
Intervention:
7 Active, not recruiting Imaging Biomarkers in ALS
Conditions: Amyotrophic Lateral Sclerosis;   Primary Lateral Sclerosis
Intervention:
8 Enrolling by invitation A Patient Centric Motor Neuron Disease Activities of Daily Living Scale
Conditions: Amyotrophic Lateral Sclerosis;   Progressive Muscular Atrophy;   Primary Lateral Sclerosis;   Hereditary Spastic Paraplegia
Intervention: Other: Web-based Survey
9 Completed Muscle Ultrasound Measures as Biomarkers of Upper Motor Neuron Function
Condition: Muscle Spasticity
Intervention:
10 Recruiting Phenotype, Genotype & Biomarkers in ALS and Related Disorders
Conditions: Amyotrophic Lateral Sclerosis;   Frontotemporal Dementia;   Primary Lateral Sclerosis;   Hereditary Spastic Paraplegia;   Progressive Muscular Atrophy;   Multisystem Proteinopathy
Intervention:
11 Completed Collection of Blood Samples for DNA in Motor Neuron Disease
Condition: Motor Neuron Diseases
Intervention:
12 Completed Levetiracetam for Cramps, Spasticity and Neuroprotection in Motor Neuron Disease
Conditions: Motor Neuron Disease;   Amyotrophic Lateral Sclerosis;   Primary Lateral Sclerosis;   Progressive Muscular Atrophy
Intervention: Biological: Levetiracetam
13 Recruiting Genetics of Familial and Sporadic ALS
Conditions: Amyotrophic Lateral Sclerosis (ALS);   Familial Amyotrophic Lateral Sclerosis;   Amyotrophic Lateral Sclerosis With Frontotemporal Dementia;   Lou Gehrig's Disease;   Motor Neuron Disease;   Primary Lateral Sclerosis
Intervention: Other: Genetic study of ALS families
14 Completed Validation of Biomarkers in Amyotrophic Lateral Sclerosis (ALS)
Conditions: Amyotrophic Lateral Sclerosis;   Lou Gehrig's Disease;   Primary Lateral Sclerosis;   Nervous System Diseases;   Hereditary Spastic Paraparesis
Intervention: Other: No intervention
15 Active, not recruiting Autologous Bone Marrow-Derived Stem Cell Therapy for Motor Neuron Disease
Conditions: Motor Neuron Disease;   Amyotrophic Lateral Sclerosis;   Primary Lateral Sclerosis;   Progressive Muscular Atrophy;   Progressive Bulbar Palsies
Intervention: Biological: Stem Cells
16 Recruiting Genomic Translation for ALS Care
Condition: ALS
Intervention:
17 Recruiting Answer ALS: Individualized Initiative for ALS Discovery
Conditions: Amyotrophic Lateral Sclerosis;   Primary Lateral Sclerosis;   Flail Arm ALS;   Progressive Muscular Atrophy;   Monomelic Amyotrophy;   Motor Neuron Disease;   Asymptomatic ALS Gene Carriers;   Healthy Controls
Intervention:
18 Completed Physiologic Studies of Spasticity
Conditions: Muscle Spasticity;   Healthy
Intervention:
19 Completed A Study of CK-2017357 in Patients With Amyotrophic Lateral Sclerosis (ALS)
Condition: Amyotrophic Lateral Sclerosis
Interventions: Drug: Placebo;   Drug: 250 mg CK-2017357;   Drug: 500 mg CK-2017357
20 Unknown  Phase II/III Randomized, Placebo-controlled Trial of Arimoclomol in SOD1 Positive Familial Amyotrophic Lateral Sclerosis
Conditions: Amyotrophic Lateral Sclerosis 1;   Acquired Amyotrophic Lateral Sclerosis;   Amyotrophic Lateral Sclerosis
Intervention: Drug: Arimoclomol

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Study has passed its completion date and status has not been verified in more than two years.