216 studies found for:    Primary Lateral Sclerosis
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Primary Lateral Sclerosis (216 records)
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Rank Status Study
1 Completed Nuclear Magnetic Spectroscopy Imaging to Evaluate Primary Lateral Sclerosis, Hereditary Spastic Paraplegia and Amyotrophic Lateral Sclerosis
Conditions: Primary Lateral Sclerosis;   Hereditary Spastic Paraplegia;   Amyotrophic Lateral Sclerosis
Intervention:
2 Recruiting Screening and Natural History: Primary Lateral Sclerosis and Related Disorders
Conditions: Motor Nueron Disease;   Nervous System Diseases;   Muscle Spasticity;   Diffusion Tensor Imaging;   Disease Progression;   Evoked Potentials, Motor/Physiology
Intervention:
3 Active, not recruiting Brain Function in Primary Lateral Sclerosis and Amyotrophic Lateral Sclerosis
Condition: Cerebral Cortex Dysfunction
Intervention:
4 Completed Brain Function in Primary Lateral Sclerosis
Condition: Motor Neuron Disease
Intervention:
5 Active, not recruiting Oxidative Stress in Motor Neuron Disease: COSMOS Add-On Study
Conditions: Motor Neuron Disease;   Primary Lateral Sclerosis
Intervention:
6 Recruiting Genetics of Familial and Sporadic ALS
Conditions: Amyotrophic Lateral Sclerosis;   Familial Amyotrophic Lateral Sclerosis;   Amyotrophic Lateral Sclerosis and Frontotemporal Dementia;   Lou Gehrig's Disease;   Motor Neuron Disease;   Primary Lateral Sclerosis
Intervention: Other: Genetic study of ALS families
7 Recruiting Phenotype, Genotype & Biomarkers in ALS and Related Disorders
Conditions: Amyotrophic Lateral Sclerosis;   Frontotemporal Dementia;   Primary Lateral Sclerosis;   Hereditary Spastic Paraplegia;   Progressive Muscular Atrophy;   Multisystem Proteinopathy
Intervention:
8 Completed Collection of Blood Samples for DNA in Motor Neuron Disease
Condition: Motor Neuron Diseases
Intervention:
9 Enrolling by invitation Muscle Ultrasound Measures as Biomarkers of Upper Motor Neuron Function
Condition: Muscle Spasticity
Intervention:
10 Completed Levetiracetam for Cramps, Spasticity and Neuroprotection in Motor Neuron Disease
Conditions: Motor Neuron Disease;   Amyotrophic Lateral Sclerosis;   Primary Lateral Sclerosis;   Progressive Muscular Atrophy
Intervention: Biological: Levetiracetam
11 Active, not recruiting Validation of Biomarkers in Amyotrophic Lateral Sclerosis (ALS)
Conditions: Amyotrophic Lateral Sclerosis;   Lou Gehrig's Disease;   Primary Lateral Sclerosis;   Nervous System Diseases;   Hereditary Spastic Paraparesis
Intervention: Other: No intervention
12 Completed Physiologic Studies of Spasticity
Conditions: Muscle Spasticity;   Healthy
Intervention:
13 Recruiting Advancing Research and Treatment for Frontotemporal Lobar Degeneration (ARTFL)
Conditions: FTLD;   Progressive Supranuclear Palsy (PSP);   Frontotemporal Dementia (FTD);   Corticobasal Degeneration (CBD);   PPA Syndrome;   Behavioral Variant Frontotemporal Dementia (bvFTD);   Semantic Variant Primary Progressive Aphasia (svPPA);   Nonfluent Variant Primary Progressive Aphasia (nfvPPA);   FTD With Amyotrophic Lateral Sclerosis (FTD/ALS);   Amyotrophic Lateral Sclerosis (ALS);   Oligosymptomatic PSP (oPSP);   Corticobasal Syndrome (CBS)
Intervention:
14 Completed A Study of CK-2017357 in Patients With Amyotrophic Lateral Sclerosis (ALS)
Condition: Amyotrophic Lateral Sclerosis
Interventions: Drug: Placebo;   Drug: 250 mg CK-2017357;   Drug: 500 mg CK-2017357
15 Recruiting Toxin Treatment for Amyotrophic Lateral Sclerosis (ALS) Related Sialorrhea
Conditions: Sialorrhea;   Amyotrophic Lateral Sclerosis
Interventions: Drug: Botox injection;   Drug: Placebo injection
16 Active, not recruiting Phase II/III Randomized, Placebo-controlled Trial of Arimoclomol in SOD1 Positive Familial Amyotrophic Lateral Sclerosis
Conditions: Amyotrophic Lateral Sclerosis 1;   Acquired Amyotrophic Lateral Sclerosis;   Amyotrophic Lateral Sclerosis
Intervention: Drug: Arimoclomol
17 Completed Safety and Efficacy of TRO19622 as add-on Therapy to Riluzole Versus Placebo in Treatment of Patients Suffering From Amyotrophic Lateral Sclerosis (ALS)
Condition: Amyotrophic Lateral Sclerosis
Interventions: Drug: Olesoxime;   Drug: Placebo Comparator
18 Completed Growth Hormone in Amyotrophic Lateral Sclerosis
Condition: Amyotrophic Lateral Sclerosis
Interventions: Drug: Growth Hormone (Somatropin);   Drug: Placebo
19 Completed Open-Label, Safety and Tolerability Extension Study of KNS-760704 in Amyotrophic Lateral Sclerosis (ALS) (CL211)
Condition: Amyotrophic Lateral Sclerosis
Intervention: Drug: KNS-760704
20 Not yet recruiting Clinical Trial of Ezogabine (Retigabine) in ALS Subjects
Condition: Amyotrophic Lateral Sclerosis
Interventions: Drug: Ezogabine;   Drug: Placebo

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Indicates status has not been verified in more than two years