1 |
NCT03283254 |
Recruiting |
PREPP: Preventing Postpartum Depression |
|
- Behavioral: Practical Resources for Effective Postpartum Parenting
- Behavioral: Enhanced Treatment As Usual
|
Interventional |
Not Applicable |
- New York State Psychiatric Institute
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Prevention
|
- Postpartum Depression Symptoms
- Improved Sleep
- Infant Behavior
- Greater infant left frontal EEG power reflecting sleep spindle activity
|
300 |
Female |
18 Years to 45 Years (Adult) |
NCT03283254 |
7428 |
PREPP |
October 17, 2017 |
July 20, 2022 |
August 10, 2022 |
September 14, 2017 |
January 29, 2018 |
|
- Elizabeth Werner
New York, New York, United States
|
2 |
NCT01658098 |
Unknown † |
Prevalence of Postpartum Depression in Hospital Jose E. Gonzalez |
|
- Behavioral: edinburgh postpartum depression scale questionary
|
Observational |
|
- Hospital Universitario Dr. Jose E. Gonzalez
|
Other |
- Time Perspective: Prospective
|
- presence of postpartum depression
- sociodemographic characteristics
- obstetrical background
- medical background
|
348 |
Female |
Child, Adult, Senior |
NCT01658098 |
etamez |
|
September 2012 |
November 2012 |
February 2013 |
August 6, 2012 |
August 6, 2012 |
|
- Hospital Universitario Dr Jose E. Gonzalez
Monterrey, Nuevo Leon, Mexico
|
3 |
NCT00782912 |
Completed |
Postpartum Anemia and Postpartum Depression |
|
|
Observational |
|
- St. Michael's Hospital, Toronto
|
Other |
- Observational Model: Case Control
- Time Perspective: Prospective
|
- Incidence of postpartum depression
- Mean Edinburgh Postnatal Depression Scale results
- Functional status
- Lactation success
|
103 |
Female |
Child, Adult, Senior |
NCT00782912 |
REB 08-155 |
PPADS |
November 2008 |
October 2014 |
October 2014 |
October 31, 2008 |
April 22, 2015 |
|
- St. Michael's Hospital
Toronto, Ontario, Canada
|
4 |
NCT03499756 |
Not yet recruiting New |
Couple-based Interpersonal Psychotherapy on Postnatal Depression and Family Sense of Coherence |
|
- Behavioral: Couple-based interpersonal psychotherapy
|
Interventional |
Not Applicable |
- The Hong Kong Polytechnic University
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Triple (Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Prevention
|
- Edinburgh Postnatal Depression Scale
- Family Sense of Coherence Scale (Short Form)
- Dyadic Adjustment Scale
|
472 |
All |
18 Years to 60 Years (Adult) |
NCT03499756 |
PolyU 156082/17H |
|
May 1, 2018 |
December 31, 2020 |
December 31, 2020 |
April 17, 2018 |
April 17, 2018 |
|
|
5 |
NCT02285504 |
Completed |
Evaluate SAGE-547 in Female Patients With Severe Postpartum Depression |
|
|
Interventional |
Phase 2 |
|
Industry |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Safety and tolerability of SAGE-547 measured by mean changes from baseline in clinical laboratory measures, vital signs, and ECGs; physical examination; and concomitant medication usage
- Pharmacokinetic (PK) profile of SAGE-547 as measured by AUC, Cmax, Tmax, Css, Cavg.
- Effects of SAGE-547 on patient symptom response evaluated by changes from baseline in Hamilton Rating Scale for Depression-17 (HAM-D-17) and individual Clinical Global Impression-Improvement (CGI-I) Scale scores
|
4 |
Female |
18 Years to 45 Years (Adult) |
NCT02285504 |
547-PPD-201 |
|
September 2014 |
June 2015 |
June 2015 |
November 7, 2014 |
April 26, 2017 |
|
- PRA Health Sciences
Marlton, New Jersey, United States - University or North Carolina, Chapel Hill - Perinatal Psychiatry In-Patient Unit
Chapel Hill, North Carolina, United States
|
6 |
NCT00384943 |
Completed |
Study of Home-Based Exercise to Alleviate Postpartum Depression |
|
- Behavioral: Moderate-intensity Exercise
|
Interventional |
Not Applicable |
- McGill University
- Fonds de la Recherche en Santé du Québec
|
Other |
- Allocation: Randomized
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Change in depressed mood scores immediately following the 3 month intervention and at 3 and 6 months post-treatment,
- as measured by the Edinburgh Postnatal Depression Scale and the Hamilton Rating Scale for Depression.
- Changes in fatigue levels (measured by the multidimensional fatigue inventory), sleep patterns, anxiety and health status.
|
90 |
Female |
18 Years and older (Adult, Senior) |
NCT00384943 |
FRSQ 024018 |
|
November 2001 |
|
November 2004 |
October 6, 2006 |
October 6, 2006 |
|
- McGill University Health Centre
Montreal, Quebec, Canada
|
7 |
NCT03417960 |
Recruiting |
Accelerated iTBS for Post Partum Depression |
|
|
Interventional |
Not Applicable |
- Medical University of South Carolina
|
Other |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Determine feasibility and tolerability of accelerated iTBS for postpartum depression. The investigators hope to retain >80% of recruited patients (feasibility) and reach a full treatment dose of 120%rMT in >80% of enrolled women (tolerability).
- Anti-depressant effect
|
20 |
Female |
18 Years to 50 Years (Adult) |
NCT03417960 |
Pro00073886 |
|
January 24, 2018 |
February 1, 2019 |
July 1, 2019 |
January 31, 2018 |
January 31, 2018 |
|
- Medical University of South Carolina
Charleston, South Carolina, United States
|
8 |
NCT00744328 |
Terminated Has Results |
Postpartum Depression: Transdermal Estradiol Versus Sertraline |
|
- Drug: Transdermal Estradiol
- Drug: Sertraline
- Other: Placebo
|
Interventional |
Phase 4 |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- To Test the Efficacy of Estradiol for the Treatment of Postpartum Depression - Percent Change in SIGH-ADS29
- Infant Development Among 6.5 Month Old Children of Mothers With PPMD, as Assessed by Bayley Scales of Infant Development
- Infant Serum Concentrations of Estradiol in 3 Treatment Arms
- (and 2 more...)
|
85 |
Female |
18 Years to 45 Years (Adult) |
NCT00744328 |
R01MH057102 |
E2SERT |
August 2008 |
September 2013 |
September 2013 |
August 29, 2008 |
October 23, 2014 |
October 23, 2014 |
- Northwestern University Feinberg School of Medicine; Asher Center for the Study and Treatment of Depressive Disorders
Chicago, Illinois, United States
|
9 |
NCT00436150 |
Completed |
Interpersonal Therapy-Based Treatment to Prevent Postpartum Depression in Adolescent Mothers |
|
- Behavioral: Interpersonal therapy-based treatment
- Behavioral: Standard care
|
Interventional |
Not Applicable |
- Women and Infants Hospital of Rhode Island
- National Institute of Mental Health (NIMH)
|
Other / NIH |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Participant)
- Primary Purpose: Prevention
|
- Postpartum depression diagnosis
- Degree of depressive symptoms
- Prenatal distress
- Social support
|
106 |
Female |
12 Years to 18 Years (Child, Adult) |
NCT00436150 |
R34MH077588 DSIR 84-CTP |
|
February 2007 |
September 2009 |
September 2009 |
February 16, 2007 |
March 12, 2013 |
|
- Women & Infants Hospital of Rhode Island
Providence, Rhode Island, United States
|
10 |
NCT03088319 |
Recruiting |
Post-natal Depression and Chronic Stress |
|
|
Observational |
|
- Institut de Recherche Biomedicale des Armees
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- post natal depression
- allostatic load as a composite index including blood GABA, BDNF and 8iso-Prostaglandins and capillary cortisol + heart rate variability index
|
260 |
Female |
18 Years to 40 Years (Adult) |
NCT03088319 |
2016-A00887-44 |
serene |
April 11, 2017 |
October 11, 2019 |
October 11, 2019 |
March 23, 2017 |
June 26, 2017 |
|
- Marion Trousselard
Brétigny-sur-Orge, Not in US/Canada, France
|
11 |
NCT00816725 |
Completed |
Effectiveness of a Web-based Prevention Program for Postpartum Depression |
- Depression
- Postpartum Depression
|
- Behavioral: Mothers and babies Internet course and PPD informational brochure
|
Interventional |
Not Applicable |
- University of California, San Francisco
- National Institute of Mental Health (NIMH)
|
Other / NIH |
- Allocation: Non-Randomized
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Prevention
|
- Edinburgh Postnatal Depression Scale (EPDS)
- Center for Epidemiologic Studies-Depression (CES-D) Scale
|
1000 |
Female |
18 Years to 60 Years (Adult) |
NCT00816725 |
F32MH077371 5A DATR AK-TAIF |
|
January 2009 |
June 2013 |
June 2013 |
January 5, 2009 |
April 11, 2014 |
|
- University of California, San Francisco
San Francisco, California, United States
|
12 |
NCT00282776 |
Completed |
Identification and Therapy of Postpartum Depression |
|
- Behavioral: Care Management for Postpartum Depression
- Behavioral: TAU
|
Interventional |
Phase 3 |
- University of Pittsburgh
- National Institute of Mental Health (NIMH)
|
Other / NIH |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Participant, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Depressive symptoms, social functioning, and health
- Preferences for depression treatment
|
628 |
Female |
18 Years and older (Adult, Senior) |
NCT00282776 |
R01MH071825 DSIR 82-SEMS |
|
August 2006 |
March 2012 |
March 2012 |
January 27, 2006 |
October 7, 2013 |
|
- Women's Behavioral HealthCARE Program, Suite 410, 3501 Forbes Ave
Pittsburgh, Pennsylvania, United States
|
13 |
NCT02191423 |
Unknown † |
Oxytocin and Dyadic Psychotherapy in the Treatment of Post Partum Depression |
|
- Drug: Oxytocin
- Drug: placebo
- Behavioral: Dyadic psychotherapy
|
Interventional |
Not Applicable |
- Tel-Aviv Sourasky Medical Center
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Triple (Participant, Investigator, Outcomes Assessor)
- Primary Purpose: Diagnostic
|
- Effect of the administration of oxytocin on cerebral circuit processing
- Interactional measures-CIB
- Interactional measures-Noldus
- (and 5 more...)
|
50 |
Female |
18 Years to 45 Years (Adult) |
NCT02191423 |
TASMC-14-MB-161-CTIL |
|
January 2015 |
June 2016 |
|
July 16, 2014 |
July 16, 2014 |
|
- The Tel-Aviv Sourasky Medical Center
Tel-Aviv, Israel
|
14 |
NCT00961402 |
Completed Has Results |
The Effect of Exercise on Preventing PostPartum Depression |
|
- Behavioral: Wellness Control
- Behavioral: Exercise Intervention
|
Interventional |
Phase 2 |
- University of Minnesota - Clinical and Translational Science Institute
- National Institute of Mental Health (NIMH)
|
Other / NIH |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Structured Clinical Interview for DSM-IV Axis I Disorders
- 7-Day Physical Activity Recall Interview
- Edinburgh Postnatal Depression Scale
- PHQ-9
|
130 |
Female |
18 Years and older (Adult, Senior) |
NCT00961402 |
R21MH085176 |
|
September 2009 |
November 2011 |
November 2011 |
August 19, 2009 |
September 15, 2016 |
July 29, 2016 |
- University of Minnesota
Minneapolis, Minnesota, United States
|
15 |
NCT00604604 |
Completed |
Postpartum Depression Prevention Trial |
|
|
Interventional |
Not Applicable |
- University of Toronto
- Canadian Institutes of Health Research (CIHR)
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Investigator)
- Primary Purpose: Prevention
|
- Structured Clinical Interview for DSM-IV (SCID-I); Edinburgh Postnatal Depression Scale (EPDS)
- State Anxiety Inventory (STAI); UCLA Loneliness Scale; Maternal Health Service Utilization and Cost of Care Questionnaire; Peer Support Evaluation Inventory; Peer Volunteer Experience Questionnaire; Peer Volunteer Activity Log
|
702 |
Female |
Child, Adult, Senior |
NCT00604604 |
MCT-66874 ISRCTN68337727 |
|
August 2004 |
April 2007 |
April 2007 |
January 30, 2008 |
June 3, 2015 |
|
- Peel Health Department
Mississauga, Ontario, Canada - Halton Region Health Department
Oakville, Ontario, Canada - Ottawa Public Health
Ottawa, Ontario, Canada - (and 4 more...)
|
16 |
NCT03346551 |
Recruiting |
Postnatal Depression, Attachment and Self-defining Memories |
|
- Behavioral: Evaluation of the quality attachment : "Adult Attachment Narratives" and "CaMir scale"
- Behavioral: Evaluation of the self-defining memories : "Specific Questionnaire during an interview"
|
Interventional |
Not Applicable |
|
Other |
- Allocation: Non-Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Basic Science
|
- Quality attachment
- First Self-defining memory
- Second Self-defining memory
- Third Self-defining memory
|
60 |
Female |
18 Years and older (Adult, Senior) |
NCT03346551 |
PA17012 |
PNDattachMEMO |
October 13, 2017 |
November 13, 2018 |
December 13, 2018 |
November 17, 2017 |
January 5, 2018 |
|
- Damien JOLLY
Reims, France
|
17 |
NCT01482832 |
Active, not recruiting |
Interpersonal Therapy-Based Treatment to Prevent Postpartum Depression in Adolescent Mothers |
|
- Behavioral: Interpersonal therapy-based treatment
|
Interventional |
Not Applicable |
- Women and Infants Hospital of Rhode Island
- National Institute of Mental Health (NIMH)
- Pacific Institute for Research and Evaluation
- Brown University
|
Other / NIH |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Prevention
|
- Diagnosis of depression
- Degree of depressive symptoms
|
250 |
Female |
12 Years to 19 Years (Child, Adult) |
NCT01482832 |
R01MH093342 |
REACH 2 |
December 2011 |
December 2017 |
April 2018 |
December 1, 2011 |
December 6, 2016 |
|
- Women & Infants Hospital
Providence, Rhode Island, United States
|
18 |
NCT01379781 |
Completed Has Results |
Behavioral Change in the Mother-Infant Dyad: Preventing Postpartum Depression |
|
- Behavioral: Behavioral Intervention for PPD
|
Interventional |
Not Applicable |
- New York State Psychiatric Institute
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Prevention
|
- Hamilton Rating Scales of Depression
|
54 |
Female |
18 Years to 35 Years (Adult) |
NCT01379781 |
#6285 |
|
August 2011 |
February 2014 |
February 2014 |
June 23, 2011 |
August 10, 2015 |
August 10, 2015 |
- Columbia University Medical Center
New York, New York, United States
|
19 |
NCT01386086 |
Completed |
Aripiprazole and Resistant Postpartum Depression |
|
|
Interventional |
Phase 3 |
- Lawson Health Research Institute
- Bristol-Myers Squibb
|
Other / Industry |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Montgomery Asberg Depression Rating Scale
- Udvalg for Kliniske Undersogelser Scale
|
10 |
Female |
18 Years to 45 Years (Adult) |
NCT01386086 |
CN138-623 |
|
June 2011 |
November 2013 |
November 2013 |
June 30, 2011 |
March 17, 2016 |
|
- Regional Mental Health Care
London, Ontario, Canada
|
20 |
NCT00833469 |
Completed Has Results |
Escitalopram (Lexapro) for the Treatment of Postpartum Depression |
|
|
Interventional |
Phase 4 |
- Massachusetts General Hospital
- Forest Laboratories
|
Other / Industry |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Change in Clinician-rated Montgomery-Asberg Depression Rating Scale (MADRS)
- Change in Edinburgh Postnatal Depression Scale (EPDS)
- Change in Beck Anxiety Inventory (BAI)
|
7 |
Female |
18 Years to 45 Years (Adult) |
NCT00833469 |
2008-P-001509 |
LexaproPPD |
January 2009 |
April 2011 |
April 2011 |
February 2, 2009 |
August 6, 2014 |
August 6, 2014 |
- Massachusetts General Hospital
Boston, Massachusetts, United States
|
21 |
NCT00370903 |
Completed |
Postpartum Depression and Cesarean Section |
|
|
Observational |
|
- Oklahoma State University Center for Health Sciences
|
Other |
- Time Perspective: Retrospective
|
|
200 |
Female |
15 Years to 43 Years (Child, Adult) |
NCT00370903 |
2005009 |
|
August 2006 |
November 2007 |
November 2007 |
September 1, 2006 |
February 4, 2008 |
|
- Oklahoma State University Center for Health Sciences Houston Parke Clinic
Tulsa, Oklahoma, United States
|
22 |
NCT00228033 |
Completed |
Effectiveness of Supplemental Calcium in Preventing Postpartum Depression |
- Depression
- Depression, Postpartum
|
- Drug: Elemental calcium (as carbonate)
|
Interventional |
Phase 4 |
- Oregon Health and Science University
- National Institute of Mental Health (NIMH)
|
Other / NIH |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double
- Primary Purpose: Prevention
|
- Score on Edinburgh Postnatal Depression Scale; measured at Weeks 6 and 12 after childbirth
- Symptoms of depression; measured throughout the study with a standard psychiatric interview
- Calcium effects on depression; measured througout pregnancy
|
238 |
Female |
18 Years and older (Adult, Senior) |
NCT00228033 |
R21MH063242 DAHBR AD-D |
|
April 2002 |
December 2005 |
August 2007 |
September 28, 2005 |
March 20, 2014 |
|
- Oregon Health & Science University
Portland, Oregon, United States
|
23 |
NCT01028482 |
Completed |
Treatment of Postpartum Depression With Psychotherapy and Add-on Sertraline |
|
- Drug: Sertraline
- Drug: placebo
- Other: psychotherapy
|
Interventional |
Not Applicable |
- Tel-Aviv Sourasky Medical Center
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Participant, Investigator)
- Primary Purpose: Treatment
|
|
42 |
Female |
18 Years to 45 Years (Adult) |
NCT01028482 |
TASMC-09-MB-301-CTIL |
|
March 2008 |
November 2010 |
January 2011 |
December 9, 2009 |
May 10, 2011 |
|
- Tel Aviv Sourasky Medical Center
Tel Aviv, Israel
|
24 |
NCT01648816 |
Active, not recruiting |
Interaction Between Genetic Factors and Maternal Stressors During Pregnancy in the Risk of Postpartum Depression |
|
|
Observational |
|
- Assistance Publique - Hôpitaux de Paris
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Depressed subjects at week 8 after delivery (EPDS and DSM I-V criteria for depression)
|
3000 |
Female |
18 Years to 60 Years (Adult) |
NCT01648816 |
AOM 10056 2010-A01315-35 |
IGEDEPP |
November 2, 2011 |
September 4, 2016 |
September 2017 |
July 24, 2012 |
June 15, 2017 |
|
- Louis Mourier Hospital
Colombes, France
|
25 |
NCT02495350 |
Completed |
The Correlation Between Prelabor Analgesic Plan and Actual Labor Analgesia With Satisfaction, Postpartum Depression, and Breast Feeding Success |
|
|
Observational |
|
|
Other |
- Observational Model: Other
- Time Perspective: Prospective
|
- Assessment of postpartum depression using Edinborough Postnatal Depression scale
- Assessment of breast feeding duration in women undergoing vaginal deliveries
- Increases in labor satisfaction defined as a vas (visual analog scale) satisfaction over 7 in women undergoing vaginal deliveries
|
1954 |
Female |
18 Years to 55 Years (Adult) |
NCT02495350 |
0666-14-RMC |
|
June 2015 |
August 2016 |
September 2016 |
July 13, 2015 |
November 17, 2017 |
|
- Beilinson hospital
Petach tikvah, Israel
|
26 |
NCT01527474 |
Completed |
Escitalopram in the Treatment of Postpartum Depression |
|
|
Interventional |
Not Applicable |
- BC Women's Hospital & Health Centre
|
Other |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- The primary efficacy assessment will be total score on the Montgomery-Asberg Depression Rating Scale (MADRS).
- The Secondary efficacy assessment will be total score on the short form of the Quality of Life Enjoyment and Satisfaction Questionnaire.
|
20 |
Female |
19 Years to 40 Years (Adult) |
NCT01527474 |
SM1562007 |
|
April 2008 |
May 2009 |
May 2009 |
February 7, 2012 |
February 10, 2012 |
|
- Reproductive Mental Health Program, BC Women's Hospital
Vancouver, British Columbia, Canada
|
27 |
NCT02862444 |
Not yet recruiting |
A Culturally Appropriate Intervention for Preventing and Reducing Postpartum Depression |
|
- Other: Culturally Appropriate Intervention
|
Observational |
|
- Clalit Health Services
- Ben-Gurion University of the Negev
|
Other |
- Time Perspective: Prospective
|
- Postpartum depression will be measured by Edinburgh Postnatal Depression Scale (EPDS)
|
382 |
Female |
16 Years to 40 Years (Child, Adult) |
NCT02862444 |
0004-16-COM2 |
|
August 2016 |
October 2018 |
October 2018 |
August 11, 2016 |
August 11, 2016 |
|
|
28 |
NCT02978326 |
Recruiting |
A Study to Evaluate SAGE-217 in Subjects With Severe Postpartum Depression |
|
- Drug: SAGE-217
- Drug: Placebo
|
Interventional |
Phase 2 |
|
Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Effect of SAGE-217 on depressive symptoms in subjects with severe postpartum depression compared to placebo as assessed by the change from baseline in Hamilton Rating Scale for Depression (HAM-D) total score
- Safety and tolerability of SAGE-217 compared to placebo as assessed by the incidence of adverse events, vital sign measurements, clinical laboratory evaluations, and electrocardiogram (ECG) parameters
- Safety and tolerability of SAGE-217 compared to placebo as assessed by the Columbia Suicide Severity Rating Scale (C-SSRS)
|
140 |
Female |
18 Years to 45 Years (Adult) |
NCT02978326 |
217-PPD-201 |
|
December 2016 |
December 2018 |
December 2018 |
November 30, 2016 |
April 17, 2018 |
|
- Sage Investigational Site
Little Rock, Arkansas, United States - Sage Investigational Site
Oceanside, California, United States - Sage Investigational Site
Wildomar, California, United States - (and 18 more...)
|
29 |
NCT02818075 |
Recruiting |
Mobile Phone Based Peer Support to Prevent Postpartum Depression Among Adolescent Mothers |
|
- Other: Mobile Phone Based Peer Support
- Other: Usual Care
|
Interventional |
Not Applicable |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Prevention
|
- Feasibility as assessed by the Participant Eligibility Assessment Form
- Acceptability as assessed by the validated Peer Support Evaluation Inventory
- Compliance as assessed by the Activity Log Form
- (and 5 more...)
|
40 |
Female |
16 Years to 24 Years (Child, Adult) |
NCT02818075 |
32189 |
|
April 2016 |
December 2016 |
December 2016 |
June 29, 2016 |
June 29, 2016 |
|
- University of Toronto
Toronto, Ontario, Canada
|
30 |
NCT00942721 |
Completed |
Cognitive Behavioral Therapy Delivered Over the Internet for Women With Postpartum Depression |
|
- Behavioral: Web-based CBT for PPD
|
Interventional |
Phase 1 |
- Oregon Research Institute
- National Institute of Mental Health (NIMH)
|
Other / NIH |
- Allocation: Non-Randomized
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Acceptability and feasibility of the Web-based treatment program for women with postpartum depression
- Clinical utility of the program in ameliorating postpartum depression symptoms
- Women's characteristics that moderate the impact of the program
|
53 |
Female |
18 Years and older (Adult, Senior) |
NCT00942721 |
R01MH084931 1R01MH084931-01A1 DSIR 83-ATP |
|
October 2009 |
April 2013 |
April 2013 |
July 21, 2009 |
November 25, 2013 |
|
- University of Iowa
Iowa City, Iowa, United States - Oregon Research Institute
Eugene, Oregon, United States - University of Melbourne
Heidelberg Heights, Victoria, Australia
|
31 |
NCT02682004 |
Unknown † |
Serotonin, Leptin and Adiponectin Level in Patients With Postpartum Depression: Controlled Study |
|
- Other: leptin, serotonin and adiponectin level
- Other: leptin,serotonin, adiponectin level
|
Observational |
|
- Zeynep Kamil Maternity and Pediatric Research and Training Hospital
|
Other |
- Observational Model: Case Control
- Time Perspective: Prospective
|
- Blood level (ng/ml) ELİSA
|
400 |
Female |
20 Years to 40 Years (Adult) |
NCT02682004 |
51 |
|
February 2016 |
April 2016 |
May 2016 |
February 15, 2016 |
February 15, 2016 |
|
- Zeynep Kamil Maternity and Pediatric Research and Training Hospital
İstanbul, Turkey
|
32 |
NCT01178008 |
Completed |
Pilot Study on the Use of Acupuncture for Postpartum Depression |
|
- Procedure: Active acupuncture
- Procedure: Placebo acupuncture
|
Interventional |
Not Applicable |
- The University of Hong Kong
- Kwong Wah Hospital
- Hospital Authority, Hong Kong
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Participant, Outcomes Assessor)
- Primary Purpose: Treatment
|
- 17-item Hamilton Depression Rating Scale
- Hospital Anxiety and Depression Scale (HADS)
- Sheehan Disability Scale
- (and 2 more...)
|
20 |
Female |
18 Years and older (Adult, Senior) |
NCT01178008 |
Acup-003 |
|
May 2010 |
December 2011 |
June 2012 |
August 9, 2010 |
January 16, 2013 |
|
- Kwong Wah Hospital
Hong Kong, Hong Kong - Queen Mary Hospital
Hong Kong, Hong Kong - Tsan Yuk Hospital
Hong Kong, Hong Kong
|
33 |
NCT01507649 |
Completed |
Effect of a Telephone-based Intervention on Postnatal Depression |
|
- Behavioral: telephone-based cognitive-behavioral intervention
|
Interventional |
Not Applicable |
- The University of Hong Kong
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Prevention
|
- Change in depressive symptoms
- Change in quality of life
|
397 |
Female |
18 Years and older (Adult, Senior) |
NCT01507649 |
09101031 |
|
July 2012 |
December 2014 |
December 2014 |
January 11, 2012 |
December 2, 2015 |
|
- The University of Hong Kong
Hong Kong, Hong Kong
|
34 |
NCT02057627 |
Completed |
Mother-Infant Intervention for Postpartum Depression and Associated Mother-Infant Relationship Dysfunction |
|
- Behavioral: Perinatal Dyadic Psychotherapy
- Behavioral: Placebo Comparator
|
Interventional |
Not Applicable |
- Spaulding Rehabilitation Hospital
- Robert Wood Johnson Foundation
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Treatment
|
- Change from baseline on maternal depression diagnosis immediately following the 3 month intervention and at 3 months post-intervention as measured by the Structured Clinical Interview for DSM-IV Axis I Disorders (SCID)
- Change from baseline in maternal depressive symptom scores immediately following the 3 month intervention and at 3 months post-intervention as measured by the Edinburgh Postnatal Depression Scale
- Mother-infant interaction (videotaped and coded) immediately following the 3 month intervention and at 3 months post-intervention
- (and 3 more...)
|
42 |
Female |
Child, Adult, Senior |
NCT02057627 |
1R21HD065156-01 |
|
June 2010 |
July 2012 |
July 2012 |
February 7, 2014 |
April 20, 2016 |
|
- MGH Insiitute of Health Professions
Boston, Massachusetts, United States
|
35 |
NCT01762943 |
Completed Has Results |
Neurophysiology of Postpartum Depression in an Experimental Model of Pregnancy and Parturition |
|
- Drug: Leuprolide Acetate
- Drug: Micronized estradiol
- Drug: Progesterone
|
Interventional |
Not Applicable |
- University of North Carolina, Chapel Hill
- Foundation of Hope, North Carolina
- North Carolina Translational and Clinical Sciences Institute
- (and 3 more...)
|
Other / NIH |
- Allocation: Non-Randomized
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Basic Science
|
- Blood-oxygen-level-dependent (BOLD) Response During Functional Magnetic Resonance Imaging (fMRI) z Statistic
- Change in Inventory of Depression and Anxiety Symptoms (IDAS) Dysphoria Score
|
36 |
Female |
22 Years to 50 Years (Adult) |
NCT01762943 |
12-1758 5R21MH101409 |
|
August 2013 |
October 13, 2016 |
October 13, 2016 |
January 8, 2013 |
November 20, 2017 |
October 17, 2017 |
- University of North Carolina at Chapel Hill
Chapel Hill, North Carolina, United States
|
36 |
NCT00548743 |
Unknown † |
Translating Research Into Practice for Postpartum Depression |
|
- Behavioral: Screening and follow up
- Behavioral: Usual care
|
Interventional |
Not Applicable |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Participant, Outcomes Assessor)
- Primary Purpose: Screening
|
- Level of depressive symptoms and level of parenting comfort
- Percent eligible women screened and of those screen positive, percent treated and followed according to protocol
|
3000 |
Female |
18 Years to 45 Years (Adult) |
NCT00548743 |
5R01HS014744-02 |
TRIPPD |
September 2005 |
|
August 2010 |
October 24, 2007 |
December 4, 2007 |
|
- Olmsted Medical Center
Rochester, Minnesota, United States
|
37 |
NCT03024645 |
Enrolling by invitation |
Be a Mom: Effectiveness of a Web-based Preventive Intervention for Postpartum Depression |
|
- Behavioral: Be A Mom
- Behavioral: Be A Mom_with_partner
- Other: Treatment as usually (TAU)
|
Interventional |
Not Applicable |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Investigator)
- Primary Purpose: Prevention
|
- Number of women with clinically significant postpartum depressive symptoms (EPDS > 12) at 4 months postpartum
- Number of women with clinically significant postpartum depressive symptoms (EPDS > 12) at 12 months postpartum
- Changes from baseline in the severity of depressive symptoms
- (and 13 more...)
|
1000 |
Female |
18 Years to 50 Years (Adult) |
NCT03024645 |
CINEICC-2-BaM SFRH/BPD/93996/2013 |
BeAMom |
August 1, 2017 |
September 1, 2018 |
June 1, 2019 |
January 19, 2017 |
October 31, 2017 |
|
- Ana Fonseca
Coimbra, Portugal
|
38 |
NCT02843022 |
Active, not recruiting |
Effectiveness of a Web-based Nursing Intervention in the Reduction of Postpartum Depression and Parenting Stress. |
|
- Behavioral: standardized electronic messages
- Behavioral: nurse phone call if requested
- Behavioral: Staff nurse phone follow-up
|
Interventional |
Not Applicable |
- Saint Anselm College
- Catholic Medical Center
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Supportive Care
|
- postpartum depression symptoms
- breastfeeding outcomes
- patient satisfaction/experience
- Parenting stress
|
683 |
Female |
18 Years and older (Adult, Senior) |
NCT02843022 |
NURS2015-3 |
|
November 2015 |
February 2018 |
February 2018 |
July 25, 2016 |
October 6, 2017 |
|
- Catholic Medical Center
Manchester, New Hampshire, United States
|
39 |
NCT00276900 |
Completed |
Sertraline for the Prevention of Recurrent Postpartum Depression |
|
|
Interventional |
Phase 3 |
- University of Pittsburgh
- National Institute of Mental Health (NIMH)
|
Other / NIH |
- Allocation: Randomized
- Intervention Model: Factorial Assignment
- Masking: Double
- Primary Purpose: Prevention
|
- Depressive symptoms (measured at Weeks 24 and 52 postpartum)
- Functioning (measured at Weeks 24 and 52 postpartum)
|
300 |
Female |
18 Years to 45 Years (Adult) |
NCT00276900 |
R01MH053735 DSIR 83-ATP |
|
December 2003 |
August 2006 |
August 2006 |
January 13, 2006 |
October 7, 2013 |
|
- Women's Behavioral HealthCare Program
Pittsburgh, Pennsylvania, United States
|
40 |
NCT00251342 |
Unknown † |
Outcome of Postnatal Depression Screening Using Edinburgh Postnatal Depression Scale |
|
- Procedure: Edinburgh Postnatal Depression Scale
|
Interventional |
Phase 2 Phase 3 |
- Chinese University of Hong Kong
- Hong Kong Department of Health
- The University of Hong Kong
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double
- Primary Purpose: Diagnostic
|
- Mother's mental health at 6 months postpartum, as measured on the EPDS and General Health Questionnaire-12 (GHQ-12), both being self-report questionnaires.
- Mother's parenting stress (measured by the Parenting Stress Index, a self-report questionnaire)
- Marital relationship satisfaction (measured by the Chinese Kansas Marital Satisfaction Scale, a self-report questionnaire)
- (and 3 more...)
|
460 |
Female |
Child, Adult, Senior |
NCT00251342 |
CRE-2005.224-T CUHK_CCT00019 |
|
October 2005 |
|
January 2008 |
November 10, 2005 |
April 5, 2007 |
|
- Maternal and Child Health Centres, Department of Health
Hong Kong, China
|
41 |
NCT02614547 |
Completed |
A Study to Evaluate SAGE-547 in Patients With Severe Postpartum Depression |
- Severe Postpartum Depression
|
- Drug: SAGE-547
- Drug: Placebo
|
Interventional |
Phase 2 |
|
Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Triple (Participant, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Effect of SAGE-547 on depressive symptoms in subjects with severe postpartum depression compared to placebo injection as measured by the change from baseline in Hamilton Rating Scale for Depression (HAMD) total score
- Safety and tolerability of SAGE-547 compared with placebo as measured by the change from baseline in the incidence of AEs, vital signs, clinical laboratory evaluations, and ECG parameters
- Safety of SAGE-547 compared to placebo as measured by the change from baseline in suicidal ideation and behavior assessed by the Columbia Suicide Severity Rating Scale (C-SSRS) score
|
21 |
Female |
18 Years to 45 Years (Adult) |
NCT02614547 |
547-PPD-202 A |
|
November 2015 |
June 2016 |
July 2016 |
November 25, 2015 |
August 8, 2017 |
|
- University of Arkansas
Little Rock, Arkansas, United States - Gainesville, Florida, United States
- University of Miami
Miami, Florida, United States - (and 11 more...)
|
42 |
NCT02942004 |
Completed |
A Study to Evaluate SAGE-547 in Patients With Severe Postpartum Depression |
- Severe Postpartum Depression
|
- Drug: SAGE-547
- Drug: Placebo
|
Interventional |
Phase 3 |
|
Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Effect of SAGE-547 on depressive symptoms in subjects with severe postpartum depression compared to placebo injection as measured by the change from baseline in Hamilton Rating Scale for Depression (HAMD) total score
- Safety and tolerability of SAGE-547 compared with placebo as measured by the change from baseline in the incidence of AEs, vital signs, clinical laboratory evaluations, and ECG parameters
- Safety of SAGE-547 compared to placebo as measured by the change from baseline in suicidal ideation and behavior assessed by the Columbia Suicide Severity Rating Scale (C-SSRS) score
|
138 |
Female |
18 Years to 45 Years (Adult) |
NCT02942004 |
547-PPD-202 B |
|
July 2016 |
September 24, 2017 |
October 19, 2017 |
October 21, 2016 |
November 14, 2017 |
|
- Sage Investigational Site
Chandler, Arizona, United States - Sage Investigational Site
Little Rock, Arkansas, United States - Sage Investigational Site
Little Rock, Arkansas, United States - (and 46 more...)
|
43 |
NCT02942017 |
Completed |
A Study to Evaluate SAGE-547 in Patients With Moderate Postpartum Depression |
- Moderate Postpartum Depression
|
- Drug: SAGE-547
- Drug: Placebo
|
Interventional |
Phase 3 |
|
Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Effect of SAGE-547 on depressive symptoms in subjects with moderate postpartum depression compared to placebo injection as measured by the change from baseline in Hamilton Rating Scale for Depression (HAMD) total score
- Safety and tolerability of SAGE-547 compared with placebo as measured by the change from baseline in the incidence of AEs, vital signs, clinical laboratory evaluations, and ECG parameters
- Safety of SAGE-547 compared to placebo as measured by the change from baseline in suicidal ideation and behavior assessed by the Columbia Suicide Severity Rating Scale (C-SSRS) score
|
108 |
Female |
18 Years to 45 Years (Adult) |
NCT02942017 |
547-PPD-202 C |
|
July 2016 |
September 17, 2017 |
October 11, 2017 |
October 21, 2016 |
November 14, 2017 |
|
- Sage Investigational Site
Chandler, Arizona, United States - Sage Investigational Site
Little Rock, Arkansas, United States - Sage Investigational Site
Little Rock, Arkansas, United States - (and 46 more...)
|
44 |
NCT02323152 |
Unknown † |
PREVENTION OF POSTPARTUM DEPRESSION DEVELOPMENT IN WOMEN WITH VERY HIGH RISK |
|
- Behavioral: psychoeducation
- Other: Standard care
|
Interventional |
Not Applicable |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Prevention
|
- Depression Scale
- Vulnerable personality
- Physical Activity Questionare
- Temperament Style
|
135 |
Female |
18 Years to 60 Years (Adult) |
NCT02323152 |
PROGEA |
PROGEA |
September 2012 |
September 2016 |
September 2016 |
December 23, 2014 |
December 23, 2014 |
|
|
45 |
NCT02235064 |
Terminated Has Results |
Prophylactic Use of Postpartum Sertraline to Prevent Postpartum Depression |
|
- Drug: Sertraline
- Drug: Placebo
|
Interventional |
Not Applicable |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Prevention
|
- Number of Participants With Development of Postpartum Depression up to 12 Weeks Following Discharge From Hospital
- Number of Participants With Adverse Reaction to Treatment Agent up to 12 Weeks Following Discharge From Hospital
- Reported Infant Weight at 4 Weeks Following Delivery
- (and 8 more...)
|
2 |
Female |
18 Years and older (Adult, Senior) |
NCT02235064 |
CUH IRB#: 14-078 |
|
July 2014 |
July 2015 |
July 2015 |
September 9, 2014 |
March 29, 2018 |
April 10, 2017 |
- Cooper University Hospital
Camden, New Jersey, United States
|
46 |
NCT02020148 |
Unknown † |
Can Oxytocin Level Predict Postpartum Depression? |
|
|
Observational |
|
- Northwestern University
- Northwestern Memorial Hospital
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Inventory of Depressive Symptomatology, Self-Report (IDS-SR-30)
|
100 |
Female |
18 Years and older (Adult, Senior) |
NCT02020148 |
00082402 |
|
December 2013 |
June 2015 |
December 2015 |
December 24, 2013 |
July 30, 2015 |
|
- Northwestern Memorial Hospital
Chicago, Illinois, United States
|
47 |
NCT03196726 |
Recruiting |
Behavioural Interventions for Postnatal Depression: a RCT Study |
|
- Behavioral: Brief Cognitive Behavioral Therapy
- Behavioral: standard management based on Clinical Practice Guideline
|
Interventional |
Not Applicable |
- Ministry of Health, Malaysia
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Participant, Care Provider)
- Primary Purpose: Treatment
|
- changes in depression level
|
54 |
Female |
18 Years and older (Adult, Senior) |
NCT03196726 |
NMRR-15-2404-26677 |
|
March 2, 2017 |
October 30, 2018 |
December 31, 2018 |
June 23, 2017 |
February 28, 2018 |
|
- Klinik Kesihatan Seksyen 7,
Shah Alam, Selangor, Malaysia - Klinik Kesihatan Kuala Lumpur
Kuala Lumpur, W.P. Kuala Lumpur, Malaysia - Klinik Kesihatan Sg Besi
Kuala Lumpur, WP Kuala Lumpur, Malaysia - (and 3 more...)
|
48 |
NCT00518830 |
Completed |
Treatment of Postnatal Depression for Low-Income Mothers in Primary Care in Santiago, Chile |
|
- Other: multi-component intervention
- Other: Usual care
|
Interventional |
Not Applicable |
- Fondo Nacional de Desarrollo Científico y Tecnológico, Chile
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Treatment
|
- EPDS
- four dimensions of the Short Form-36 (SF-36) Questionnaire: mental health; emotional role; social functioning; and vitality(34) and significant clinical improvement.
|
230 |
Female |
18 Years and older (Adult, Senior) |
NCT00518830 |
1040434 |
DPP |
March 2004 |
|
July 2006 |
August 21, 2007 |
August 21, 2007 |
|
|
49 |
NCT00560027 |
Completed |
Case Management Study for Postpartum Depression and Intimate Partner Violence |
- Postpartum Depression
- Intimate Partner Violence
|
- Other: Case Management by Family Support Counselor (not RCT)
|
Interventional |
Not Applicable |
- Johns Hopkins University
- Leonard & Helen R. Stulman Charitable Foundation
|
Other |
- Allocation: Non-Randomized
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Screening
|
- Positive screens for PPD and/or IPV
- Healthcare utilization over 2 years (acute care, emergency and well visits)
|
173 |
Female |
Child, Adult, Senior |
NCT00560027 |
20064046 |
|
July 2010 |
June 2013 |
June 2013 |
November 19, 2007 |
May 28, 2015 |
|
- Harriet Lane Clinic
Baltimore, Maryland, United States
|
50 |
NCT01002027 |
Completed |
Three Model Care Pathways for Postnatal Depression |
|
- Behavioral: CBT-Counselling
|
Interventional |
Not Applicable |
- University of Melbourne
- Beyondblue (The National Depression Initiative)
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Treatment
|
- Clinical Depression Score
|
68 |
Female |
18 Years and older (Adult, Senior) |
NCT01002027 |
H2005/01895 |
|
November 2004 |
February 2007 |
February 2007 |
October 27, 2009 |
October 27, 2009 |
|
- Austin Health
Melbourne, Victoria, Australia
|