| 1 |
NCT01562860 |
Recruiting |
Influence of Pronator Teres Release on Treatment of Median Nerve Compression Neuropathy |
|
- Procedure: Pronator Teres Release
- Procedure: dual compression release
- Procedure: median nerve release only
|
Interventional |
Phase 2 |
- Christine M. Kleinert Institute for Hand and Microsurgery
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Symptom severity and functional status score (Brigham and Women's Carpal Tunnel Questionnaire)
|
100 |
All |
18 Years to 65 Years (Adult) |
NCT01562860 |
10.0039 |
|
July 2010 |
July 2019 |
July 2019 |
March 26, 2012 |
January 25, 2018 |
|
- Christine M. Kleinert Institute for Hand and Microsurgery
Louisville, Kentucky, United States
|
| 2 |
NCT02023476 |
Completed |
Neurologic Examination of Wide and Narrow Tourniquets |
|
|
Interventional |
Not Applicable |
- Medical University of Vienna
|
Other |
- Allocation: Randomized
- Intervention Model: Crossover Assignment
- Masking: None (Open Label)
|
|
18 |
All |
18 Years to 45 Years (Adult) |
NCT02023476 |
HEM |
HEM |
April 2010 |
September 2010 |
September 2010 |
December 30, 2013 |
January 10, 2014 |
|
- RIAO, Sinai Hospital Baltimore
Baltimore, Maryland, United States
|
| 3 |
NCT00987571 |
Completed |
Carpal Tunnel Syndrome: Case Reports and Analysis - Ultrasound Imaging and Pathomechanics of Median Nerve Compression |
|
|
Observational |
|
- EMG Labs of Arizona Arthritis & Rheumatology Associates
|
Other |
- Observational Model: Case Control
- Time Perspective: Prospective
|
- Median nerve compressive narrowing on ultrasound imaging in carpal tunnel syndrome patients
- No median nerve compressive narrowing in normal subjects
|
4 |
All |
18 Years to 90 Years (Adult, Senior) |
NCT00987571 |
CTS-US Med N JAOA |
|
April 2009 |
September 2009 |
September 2009 |
October 1, 2009 |
October 1, 2009 |
|
|
| 4 |
NCT00703209 |
Completed |
Study on the Role of Decompression of Lower Extremity Nerves for the Treatment of Patients With Symptomatic Diabetic Neuropathy With Chronic Nerve Compression |
- Painful Diabetic Neuropathy
|
- Procedure: Nerve Decompression
|
Interventional |
Not Applicable |
- University of Texas Southwestern Medical Center
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Participant, Outcomes Assessor)
- Primary Purpose: Treatment
|
- To determine if nerve decompression of lower extremities in patients suffering from painful symptomatic diabetic neuropathy with chronic nerve compression, has a significant impact on alleviation of pain, and improvement in quality of life.
- To measure changes in quality of life. This includes medication changes, pain relief, restoration of sensation, etc.
|
138 |
All |
18 Years to 80 Years (Adult, Senior) |
NCT00703209 |
UTSW-001 |
DNND |
January 2008 |
September 2013 |
September 2013 |
June 23, 2008 |
May 28, 2015 |
|
- UT Southwestern Medical Center
Dallas, Texas, United States
|
| 5 |
NCT02739945 |
Completed |
Sonographic Examination Cubital Tunnel Release |
- Ulnar Nerve Compression, Cubital Tunnel
|
- Procedure: Cubital tunnel release
|
Interventional |
Phase 3 |
- Ente Ospedaliero Cantonale, Bellinzona
|
Other |
- Allocation: Non-Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- American Shoulder and Elbow Society Function Score
- Jamar dynamometer (grip strength)
- Static-2 point discrimination test
- 4-point Likert-type scale
|
60 |
All |
35 Years to 85 Years (Adult, Senior) |
NCT02739945 |
EnteOC |
SPECTRE |
May 2011 |
January 2016 |
April 2016 |
April 15, 2016 |
April 15, 2016 |
|
- Dr.Lucchina Stefano
Locarno, Canton Ticino, Switzerland
|
| 6 |
NCT01994434 |
Completed |
Ulnar Nerve Deep Branch Compression by a Ganglion |
- Guyon's Canal
- Nerve Compression
|
- Procedure: Decompression of the ulnar nerve
|
Interventional |
Not Applicable |
- The Second Hospital of Tangshan
- Chinese PLA General Hospital
|
Other |
- Intervention Model: Single Group Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Treatment
|
- Grip strength
- Tip pinch strength
- Modified Bishop's scoring system
|
9 |
All |
18 Years to 70 Years (Adult, Senior) |
NCT01994434 |
TSWang9804
HEBEI-J0821 |
|
March 2000 |
October 2011 |
November 2012 |
November 25, 2013 |
November 25, 2013 |
|
- The Second Hospital of Tangshan
Tangshan, Hebei, China
|
| 7 |
NCT02532582 |
Enrolling by invitation |
Assessment of Patient Positioning |
|
|
Observational |
|
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- A change in arterial line wave form and a change in the neuromuscular signal using SSEP or EPAD will be measured and tested with the Pearson correlation coefficient as well as nonparametric Spearman's rank correlation coefficient.
|
40 |
All |
21 Years to 80 Years (Adult, Senior) |
NCT02532582 |
STU00105002 |
|
May 2015 |
July 2018 |
July 2018 |
August 26, 2015 |
January 31, 2018 |
|
|
| 8 |
NCT01961011 |
Unknown † |
Bilateral vs Unilateral CTR |
|
|
Observational |
|
- Washington University School of Medicine
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Change in QuickDASH score
- World Health Organization Health and Performance Questionnaire
|
120 |
All |
18 Years and older (Adult, Senior) |
NCT01961011 |
201206073 |
|
June 2012 |
July 2013 |
March 2014 |
October 11, 2013 |
October 11, 2013 |
|
- Washington University School of Medicine
St. Louis, Missouri, United States - Washington University School of Medicine
St. Louis, Missouri, United States
|
| 9 |
NCT00220675 |
Terminated |
Erythropoietin Spinal Cord Compression Randomized Trial |
- Nerve Compression Syndromes
|
- Drug: Erythropoietin infusion
|
Interventional |
Phase 2
Phase 3 |
- Sunnybrook Health Sciences Centre
- Ortho Biotech, Inc.
|
Other / Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Overall survival
- Recovery of ambulation
- Deep vein thrombosis rate post-treatment
- (and 3 more...)
|
7 |
All |
19 Years and older (Adult, Senior) |
NCT00220675 |
9427-T0926-28C |
|
August 2005 |
July 2007 |
July 2007 |
September 22, 2005 |
May 22, 2008 |
|
- London Regional Health Science Center
London, Ontario, Canada - Ottawa Regional Cancer Center
Ottawa, Ontario, Canada - Sunnybrook & Women's College Health Science Centre
Toronto, Ontario, Canada
|
| 10 |
NCT01051869 |
Active, not recruiting |
Simple Decompression Versus Anterior Transposition of the Ulnar Nerve |
- Humeral Fractures
- Ulnar Nerve Compression
|
- Procedure: Simple decompression
- Procedure: anterior subcutaneous transposition
|
Interventional |
Not Applicable |
- St. Michael's Hospital, Toronto
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- The primary outcome will be signs of ulnar neuropathy, measured using two clinical staging systems to assess the degree of dysfunction of the ulnar nerve (the classification system of Gabel and Amadio13).
- Secondary outcome measurement will include a patient-oriented, limb-specific, functional measurement questionnaire (Disabilities of the Arm, Shoulder and Hand Instrument-DASH)
|
56 |
All |
16 Years to 60 Years (Child, Adult) |
NCT01051869 |
Ulnar Nerve 06-Jan-10 |
|
September 2010 |
March 2018 |
March 2018 |
January 20, 2010 |
November 27, 2017 |
|
- St. Michael's Hospital
Toronto, Ontario, Canada
|
| 11 |
NCT00184158 |
Completed |
Treatment for Cubital Tunnel Syndrome |
|
|
Interventional |
Not Applicable |
- Norwegian University of Science and Technology
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- pain
- electroneurography (ENG
- paresthesia
- (and 2 more...)
|
81 |
All |
Child, Adult, Senior |
NCT00184158 |
056-02 |
|
January 2005 |
January 2009 |
January 2009 |
September 16, 2005 |
August 22, 2017 |
|
- St Olavs Hospital
Trondheim, Norway
|
| 12 |
NCT03341182 |
Not yet recruiting |
The Effects of Use of Mirror Image on Radiation Exposure During Fluoroscopically Guided Transforaminal Epidural Injection |
- Lumbar Radiculopathy Due to Spinal Nerve Compression
|
- Procedure: Fluoroscopically Guided Lumbar Transforaminal Epidural Injections
- Procedure: conventional manner
|
Interventional |
Not Applicable |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Participant, Investigator)
- Primary Purpose: Supportive Care
|
- radiation exposure time(second)
|
50 |
All |
20 Years to 80 Years (Adult, Senior) |
NCT03341182 |
4-2017-0801 |
|
November 2017 |
October 20, 2018 |
October 20, 2018 |
November 14, 2017 |
November 14, 2017 |
|
- Dept. of Anesthesiology and Pain Medicine, Yonsei University College of Medicine
Seoul, Korea, Republic of
|
| 13 |
NCT03308136 |
Recruiting |
The Effect of Local Anesthetic Injection Depth on Procedural Pain and Discomfort During Fluoroscopically Guided Lumbar Transforaminal Epidural Injections |
- Lumbar Radiculopathy Due to Spinal Nerve Compression
|
- Procedure: 1ml of local anesthetics (1% Lidocaine) were injected into the subcutaneous layer.
- Procedure: 1ml of a local anesthetics (1% idocaine) are first injected into the subcutaneous layer, followed by 3~4ml of local anesthetics to the muscle layer along the expected needle pathway.
- Drug: 1% Lidocaine
|
Interventional |
Not Applicable |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Participant, Investigator)
- Primary Purpose: Supportive Care
|
- Procedural Pain score (NRS)
- At the next outpatient visit, whether the injection site pain(Yes) or not(No)
|
68 |
All |
20 Years to 80 Years (Adult, Senior) |
NCT03308136 |
4-2017-0683 |
|
October 16, 2017 |
December 30, 2017 |
January 30, 2018 |
October 12, 2017 |
November 28, 2017 |
|
- Dept. of Anesthesiology and Pain Medicine, Yonsei University College of Medicine,
Seoul, Korea, Republic of
|
| 14 |
NCT02281227 |
Unknown † |
Determination of a Proper Needle Entry Point; Effects of Skin Compression With an Indicator on Radiation Exposure Time of Fluoroscopically Guided Transforaminal Epidural Block in Obese Patients |
- Low Back Pain Due to Spinal Nerve Compression
|
- Procedure: skin compression
|
Interventional |
Not Applicable |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Participant)
|
- Total radiation exposure time
- The number of the needle readjustments
|
64 |
All |
20 Years to 80 Years (Adult, Senior) |
NCT02281227 |
4-2014-0721 |
|
October 2014 |
March 2015 |
March 2015 |
November 3, 2014 |
November 3, 2014 |
|
- Department of Anesthesiology and Pain Medicine, Yonsei University College of Medicine
Seoul, Korea, Republic of
|
| 15 |
NCT02402335 |
Unknown † |
Study of Different Types of Backache in Groups of Patients With Different Diagnoses of Degenerative Diseases |
|
|
Observational |
|
- University Hospital, Bonn
|
Other |
- Observational Model: Case Control
- Time Perspective: Prospective
|
- Backache objectified by the PainDETECT Questionnaire
|
80 |
All |
15 Years and older (Child, Adult, Senior) |
NCT02402335 |
UKBORTAB01 |
|
February 2015 |
October 2016 |
January 2017 |
March 30, 2015 |
March 30, 2015 |
|
- University Hospital of Bonn
Bonn, NRW, Germany
|
| 16 |
NCT03476486 |
Completed |
A Pilot Study to Evaluate the Effectiveness of Ultrasound Guided Looped Thread Carpal Tunnel Release |
|
- Procedure: Thread carpal tunnel release
|
Interventional |
Phase 2 |
|
Other |
- Allocation: Non-Randomized
- Intervention Model: Single Group Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Treatment
|
- Early recovery
- Boston Carpal Tunnel Questionnaire
- Hand sensation
- (and 4 more...)
|
20 |
|
Child, Adult, Senior |
NCT03476486 |
Pro00060817 |
|
May 20, 2016 |
January 20, 2018 |
January 20, 2018 |
March 26, 2018 |
March 26, 2018 |
|
|
| 17 |
NCT02339142 |
Not yet recruiting |
Combined Radiotherapy and Intravenous Steroids for Early Progressive Thyroid Eye Disease |
|
- Radiation: External beam radiotherapy
- Drug: intravenous corticosteroids (methylprednisolone)
|
Interventional |
Phase 4 |
- University of British Columbia
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Prevention
|
- New onset dysthyroid optic neuropathy
- Progression in ocular motility dysfunction (Improvement or worsening in motility scores and ocular restriction, and need for strabismus surgery)
- Participants escaping trial (Number of participants leaving trial because of onset of optic neuropathy or primary strabismus)
- (and 4 more...)
|
100 |
All |
35 Years and older (Adult, Senior) |
NCT02339142 |
H14-03166 |
CRISEPTED |
January 2015 |
December 2018 |
December 2019 |
January 15, 2015 |
January 15, 2015 |
|
|
| 18 |
NCT01762085 |
Unknown † |
Nerve Decompression for Ulcer Recurrence Avoidance (DURA) |
- Diabetic Ulcer of Plantar Aspect of Left Foot
- Diabetic Ulcer of Plantar Aspect of Right Foot
- Diabetic Polyneuropathy
|
- Procedure: nerve decompression
|
Interventional |
Not Applicable |
- Association of Extremity Nerve Surgeons
- Association of Extremity Nerve Surgeons
|
Other |
- Allocation: Randomized
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Prevention
|
- occurrence of plantar foot ulceration wound
- occurrence of delayed wound healing
- Visual Analog Pain Score
|
120 |
All |
18 Years to 80 Years (Adult, Senior) |
NCT01762085 |
WIRB 20122035
Nerve DURA |
DURA |
June 2013 |
December 2016 |
December 2016 |
January 7, 2013 |
June 26, 2015 |
|
- Barrett Foot & Ankle Institute
Phoenix, Arizona, United States - Richard P. Jacoby
Scottsdale, Arizona, United States - Southern Arizona Limb Salvage Alliance,
Tucson, Arizona, United States - (and 3 more...)
|
| 19 |
NCT02351544 |
Recruiting |
Prospective, Multi-Center Evaluation of the Efficacy of Peripheral Trigger Decompression Surgery for Migraine Headaches |
|
- Drug: Botulinum Toxin Type A
- Procedure: Surgery
- Other: Daily headache diary
- (and 3 more...)
|
Interventional |
Not Applicable |
- Ohio State University
- University of Wisconsin, Madison
- Massachusetts General Hospital
- University Hospitals Cleveland Medical Center
|
Other |
- Allocation: Non-Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Migraine Headache Index (MHI) at 3 months
- Migraine Headache Index (MHI) at 6 months
- Migraine Headache Index (MHI) at 1 year
- (and 12 more...)
|
100 |
All |
18 Years and older (Adult, Senior) |
NCT02351544 |
2015H0024 |
|
September 2015 |
December 2019 |
December 2019 |
January 30, 2015 |
April 10, 2018 |
|
- Peled Plastic Surgery
San Francisco, California, United States - Premier Plastic Surgery of Kansas City
Olathe, Kansas, United States - Massachusetts General Hospital
Boston, Massachusetts, United States - (and 3 more...)
|
| 20 |
NCT03391336 |
Completed |
Median Nerve Injury in US-guided Carpal Tunnel Injections |
- Injury of Median Nerve Distal to Forearm
- Carpal Tunnel Syndrome
|
|
Observational |
|
- yi-chih HSU
- Tri-Service General Hospital
|
Other |
- Observational Model: Case-Only
- Time Perspective: Retrospective
|
- The observation of median nerve injury
- The intra-rater agreement of measurements
- The relationship between pre-injection factors and MNI
- (and 2 more...)
|
126 |
All |
20 Years and older (Adult, Senior) |
NCT03391336 |
TSGHIRB 2-105-05-110 |
|
February 1, 2017 |
September 30, 2017 |
December 1, 2017 |
January 5, 2018 |
January 5, 2018 |
|
- No. 325, Sec. 2, Cheng-kung Rd., Neihu 114
Taipei, Taiwan, R.o.c., Taiwan
|
| 21 |
NCT03337178 |
Not yet recruiting |
Fitbit Pilot Study in Post-operative Lumbar Degenerative Spinal Stenosis Patients |
- Lumbar Degenerative Spinal Stenosis
|
- Behavioral: Blinded Fitbit
- Behavioral: Fitbit
|
Interventional |
Not Applicable |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Care Provider)
- Primary Purpose: Other
|
- Self-Paced Walking Test
- Patient Recruitment
- Self-paced walking test
- (and 4 more...)
|
60 |
All |
60 Years and older (Adult, Senior) |
NCT03337178 |
109351 |
|
November 2017 |
July 2019 |
July 2020 |
November 8, 2017 |
November 14, 2017 |
|
- London Health Sciences Centre
London, Ontario, Canada
|
| 22 |
NCT03299361 |
Completed |
Diffusion Tensor Imaging of the Median Nerve Before and After Carpal Tunnel Corticosteroid Injection in Patients With Carpal Tunnel Syndrome: Feasibility Study |
|
- Other: Magnetic resonance image (MRI)
|
Observational |
|
- Tri-Service General Hospital
|
Other |
- Observational Model: Case-Only
- Time Perspective: Prospective
|
- Inter-scan change of DTI at baseline and 2 weeks after injection
- Correlation of Inter-scan change of DTI with symptoms relief
|
12 |
All |
Child, Adult, Senior |
NCT03299361 |
TSGHIRB 1-105-05-056 |
|
May 26, 2016 |
December 31, 2016 |
March 7, 2017 |
October 3, 2017 |
October 3, 2017 |
|
|
| 23 |
NCT02281656 |
Unknown † |
Prospective Evaluation of Reverse End to Side Anterior Interosseous Nerve to Ulnar Nerve Transfer for Severe Compressive Ulnar Neuropathy at the Elbow |
- Severe Compressive Ulnar Nerve Neuropathy (McGowan Grade III)
|
- Procedure: Surgery:ulnar nerve transposition with AIN to ulnar nerve transfer
- Procedure: Surgery:ulnar nerve subcutaneous transposition without AIN to ulnar nerve transfer.
|
Interventional |
Phase 3 |
- Lawson Health Research Institute
- Dr Christopher Doherty
- Dr Thomas Miller
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- pain scores on the numeric pain rating scale
- evaluation of reinnvervation of hand intrinsic muscles
- functional performance assessment on the numeric scale
|
40 |
All |
18 Years to 70 Years (Adult, Senior) |
NCT02281656 |
7126 |
|
January 2015 |
October 2015 |
October 2016 |
November 3, 2014 |
January 9, 2015 |
|
|
| 24 |
NCT03328351 |
Completed |
Effect of Manual Therapy on Sensory Features in Patients With Cervical Radiculopathy |
|
- Other: manual therapy
- Other: Superficial soft tissue massage
|
Interventional |
Not Applicable |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Participant, Outcomes Assessor)
- Primary Purpose: Treatment
|
- pressure pain threshold (PPT)
- Warmth/cold detection threshold and heat/cold pain threshold
- The Neck Disability Index (NDI)
- (and 2 more...)
|
28 |
All |
35 Years to 65 Years (Adult) |
NCT03328351 |
Dammam University |
|
December 18, 2016 |
August 24, 2017 |
August 24, 2017 |
November 1, 2017 |
November 1, 2017 |
|
- East jeddah general hospital
Jeddah, Saudi Arabia - king Abdulaziz hospital
Jeddah, Saudi Arabia
|
| 25 |
NCT01927406 |
Withdrawn |
The Secondary Beneficial Effects of Prostaglandin Analog Treatment in Thyroid Eye Disease Patients. |
- Thyroid Eye Disease
- Ocular Hypertension
- Glaucoma
|
- Drug: Prostaglandin Analog
- Drug: Timolol
|
Interventional |
Phase 4 |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Prevention
|
- Change from baseline in appearance of facial periorbital region at 6 months.
- Change from baseline in Hertel exophthalmometry at 3, 6, 9 and 12 months.
- Change from baseline in intraocular pressure at 3, 6, 9 and 12 months.
- Change from baseline in appearance of facial periorbital region at 3, 6, 9 and 12 months.
|
0 |
All |
18 Years and older (Adult, Senior) |
NCT01927406 |
26654 |
|
June 2014 |
December 2016 |
December 2016 |
August 22, 2013 |
January 16, 2018 |
|
- Stanford Hospital and Clinics
Stanford, California, United States
|
| 26 |
NCT01236924 |
Unknown † |
Effectiveness of Global Postural Reeducation in Patients With Chronic Symptomatic Lumbar Disc Herniation |
|
- Other: Global postural reeducation
|
Interventional |
Phase 1 |
|
Other |
- Primary Purpose: Treatment
|
|
|
Male |
25 Years to 45 Years (Adult) |
NCT01236924 |
112.2010 |
|
January 2011 |
|
|
November 9, 2010 |
November 9, 2010 |
|
- Gama Filho University
Rio de Janeiro, RJ, Brazil
|
| 27 |
NCT02466841 |
Enrolling by invitation |
Prospective Comparison of Techniques for Cubital Tunnel Release |
|
- Procedure: Cubital tunnel release
|
Observational |
|
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Patient rated ulnar nerve evaluation (PRUNE) score
- Elbow Range of Motion
- Visual Analog Scale (VAS) for Pain
- (and 3 more...)
|
200 |
All |
18 Years and older (Adult, Senior) |
NCT02466841 |
PRO15040063 |
|
August 2015 |
September 2020 |
September 2020 |
June 9, 2015 |
October 31, 2017 |
|
|
| 28 |
NCT03495661 |
Not yet recruiting
New |
Decompression vs Physical Training for the Treatment of Lumbar Spinal Stenosis |
- Spinal Stenosis
- Spinal Stenosis Lumbar
- Degeneration Lumbar Spine
- (and 3 more...)
|
|
Interventional |
Not Applicable |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Participant, Care Provider)
- Primary Purpose: Treatment
|
- Oswestry Disability Index (ODI)
- Motor Amplitude (ENG)
- Denervation Activity (EMG)
- (and 11 more...)
|
120 |
All |
50 Years to 85 Years (Adult, Senior) |
NCT03495661 |
u1 |
UppSten |
April 30, 2018 |
December 2021 |
December 2021 |
April 12, 2018 |
April 19, 2018 |
|
|
| 29 |
NCT03253523 |
Not yet recruiting |
Post-traumatic Occipital Neuralgia - Surgical Versus Medical Management |
- Post-Traumatic Neuralgia
- Occipital Neuralgia
|
- Procedure: Occipital neurolysis
|
Interventional |
Not Applicable |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Average visual analogue scale of pain intensity
- Headache days per month
- Duration of average headache
- (and 5 more...)
|
25 |
All |
18 Years to 65 Years (Adult) |
NCT03253523 |
IRB00148116 |
|
July 1, 2018 |
July 1, 2019 |
January 1, 2020 |
August 18, 2017 |
March 7, 2018 |
|
|
| 30 |
NCT00299052 |
Completed |
Efficacy of DBM on Fractures of the Shinbone (Tibia) |
- Closed Fracture
- Open Fracture
|
- Device: Grafton DBM
- Biological: Reamings
|
Interventional |
Phase 4 |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
|
16 |
All |
18 Years and older (Adult, Senior) |
NCT00299052 |
1272-2005
3006 |
|
March 2006 |
December 2007 |
September 2008 |
March 6, 2006 |
September 24, 2013 |
|
- Grady Memorial Hospital
Atlanta, Georgia, United States
|
| 31 |
NCT01433536 |
Terminated |
Evaluation of Circulating Osteogenic Factors in Trauma Patients |
- Healthy
- High Velocity Fracture
- Cranial Trauma
- Spinal Trauma
|
|
Observational |
|
- Centre de recherche du Centre hospitalier universitaire de Sherbrooke
- Université de Sherbrooke
- Canadian Institutes of Health Research (CIHR)
|
Other |
- Observational Model: Cohort
- Time Perspective: Cross-Sectional
|
|
40 |
All |
18 Years to 65 Years (Adult) |
NCT01433536 |
10-100
MOP-115149 |
BMP-9 |
December 2010 |
December 1, 2017 |
December 1, 2017 |
September 14, 2011 |
January 24, 2018 |
|
- Centre Hospitalier Universitaire de Sherbrooke
Sherbrooke, Quebec, Canada
|
| 32 |
NCT00775333 |
Completed |
Nerve Entrapment in Diabetic Patients |
- Carpal Tunnel Syndrome
- Entrapment Neuropathies
- Nerve Compression Syndromes
- Diabetes Complications
|
- Procedure: Outcome after carpal tunnel release
|
Observational |
|
- Skane University Hospital
|
Other |
- Observational Model: Case Control
- Time Perspective: Prospective
|
- Sensory function (Semmens-Weinstein), motor function (Abductor Pollicis Brevis (APB)-strength, grip strength)
- Pillar pain, cold intolerance, and patient satisfaction.
|
67 |
All |
18 Years to 80 Years (Adult, Senior) |
NCT00775333 |
LU 508-03 |
|
December 2003 |
|
April 2008 |
October 20, 2008 |
October 20, 2008 |
|
- Dept. of Hand Surgery, Malmo University Hospital
Malmo, Sweden
|
| 33 |
NCT00646295 |
Unknown † |
Pascal Pascal Dynamic Contour Tonometer (DCT) Intraocular Pressure and Ocular Pulse Amplitude in Patients With Thyroid Related Orbitopathy: A Comparison to Goldmann Tonometer and to Muscles Characteristics on CT Scan |
- Thyroid Related Orbitopathy
|
- Device: To measure the IOP (with Goldmann and Pascal DCT tonometers) and OPA (with Pascal DCT) in primary and upright gazes
|
Interventional |
Not Applicable |
|
Other |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Diagnostic
|
- IOP in primary and upright gazes measured by Goldmann and Pascal Dynamic Contour tonometers.
- The change in IOP & OPA as measured by Pascal Dynamic Contour Tonometer following an upright gaze
|
30 |
All |
18 Years and older (Adult, Senior) |
NCT00646295 |
SHEBA-08-5058-ER-CTIL |
|
June 2008 |
June 2010 |
September 2010 |
March 28, 2008 |
June 19, 2008 |
|
- Goldschleger Eye Institute, Sheba Medical Center
Tel-Hashomer, Ramat-Gan, Israel
|
| 34 |
NCT01945554 |
Completed |
The Value of Short-term Pain Relief for the Prediction of Long-term Outcome After Cervical or Lumbar Nerve Root Infiltration |
- Cervical Disc Herniation
- Lumbar Disc Herniation
|
- Procedure: Cervical nerve root infiltration
- Procedure: Lumbar nerve root infiltration
- Drug: Mephamesone
- (and 2 more...)
|
Interventional |
Not Applicable |
- Holger Joswig
- Cantonal Hospital of St. Gallen
|
Other |
- Allocation: Non-Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Health-related quality of life (HRQoL)
- Neck Pain and Disability Scale (NPAD)
- Oswestry Disability Index (ODI)
- (and 9 more...)
|
250 |
All |
18 Years to 70 Years (Adult, Senior) |
NCT01945554 |
EKSG 13/061 |
InfStu |
July 2013 |
March 2017 |
March 2017 |
September 18, 2013 |
January 25, 2018 |
|
- Flawil Hospital
Flawil, Saint Gallen, Switzerland - Rorschach Hospital
Rorschach, Saint Gallen, Switzerland - Cantonal Hospital St. Gallen
St. Gallen, Switzerland
|
| 35 |
NCT01019824 |
Completed |
Efficacy and Safety of Ralfinamide in Patients With Chronic Neuropathic Low Back Pain |
|
|
Interventional |
Phase 3 |
- Newron Pharmaceuticals SPA
- Parexel
- CliniRx
|
Industry / Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- The primary efficacy variable will be the change from baseline in the mean weekly pain score (11-point Likert scale).
|
411 |
All |
18 Years to 85 Years (Adult, Senior) |
NCT01019824 |
NW-1029/01-08
EudraCT Nr.: 2008-006176-30 |
|
March 20, 2009 |
May 11, 2010 |
August 9, 2011 |
November 25, 2009 |
September 15, 2017 |
|
- Parexel
London, England, United Kingdom
|
| 36 |
NCT00212394 |
Completed |
Tourniquet Complications in Orthopaedic Surgery |
- Tourniquet Complications
- Paresis
- Palsy
- Nerve Compression
|
|
Observational |
|
- Norwegian University of Science and Technology
|
Other |
- Time Perspective: Prospective
|
|
10 |
All |
Child, Adult, Senior |
NCT00212394 |
ADOD1 |
|
January 2005 |
September 2005 |
September 2005 |
September 21, 2005 |
March 13, 2017 |
|
- St Olavs Hospital
Trondheim, Norway
|
| 37 |
NCT02239601 |
Completed |
Chemotherapy Induced Peripheral Neuropathy. Could Physical Therapy Help Treat Symptoms? |
- Breast Cancer
- Peripheral Neuropathy, Secondary to Drugs or Chemicals
|
|
Interventional |
Not Applicable |
- CancerCare Manitoba
- University of Manitoba
|
Other |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Change from baseline in Quantitative Sensory Testing
- Number of chemotherapy dose reductions or treatment delays due to severity of nerve pain from the chemotherapy induced neuropathy
- Change from baseline on self-report questionnaire of upper limb function ( Disabilities of the Shoulder, Arm and Hand DASH)
- Change from baseline for neuropathic pain measured by the Self reported Leeds Assessment Scale for Neuropathic Symptoms and SIgns (S-LANSS)
|
56 |
All |
18 Years and older (Adult, Senior) |
NCT02239601 |
H2014:281 |
|
December 1, 2014 |
November 1, 2017 |
November 2017 |
September 15, 2014 |
January 26, 2018 |
|
- Rehabilitation Hospital, Health Sciences Centre, 800 Sherbrook St
Winnipeg, Manitoba, Canada
|
| 38 |
NCT01201109 |
Unknown † |
Carpal Tunnel Release in Diabetic Patients |
- Carpal Tunnel Syndrome
- Diabetes
- Nerve Entrapment
|
|
Observational |
|
- Skane University Hospital
|
Other |
- Observational Model: Case Control
- Time Perspective: Prospective
|
- Patient self-reported outcome questionnaire
- Nerve conduction study and vibrotactile sense
|
66 |
All |
18 Years to 80 Years (Adult, Senior) |
NCT01201109 |
2010/354 |
|
November 2010 |
December 2011 |
December 2011 |
September 14, 2010 |
September 28, 2010 |
|
- Dept of Hand Surgery, Skåne University Hospital
Malmö, Sweden
|
| 39 |
NCT01093209 |
Completed |
Efficacy of the Interferential Laser Therapy in Pain Reduction in Carpal Tunnel Syndrome |
- Carpal Tunnel Syndrome
- Neuropathic Pain
|
- Device: Interferential Laser Therapy
|
Interventional |
Phase 2 |
- Hospital Universitario Ramon y Cajal
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Participant, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Visual Analogue Scale (VAS)
- Disability Arm Shoulder and Hand questionnaire (DASH)
- Boston Carpal Tunnel Questionnaire
- Dinamometry
|
100 |
All |
18 Years to 80 Years (Adult, Senior) |
NCT01093209 |
Ramón y Cajal Hospital |
|
February 2010 |
April 2010 |
April 2011 |
March 25, 2010 |
June 28, 2011 |
|
- Ramón y Cajal University Hospital
Madrid, Spain
|
| 40 |
NCT02429947 |
Completed |
An Analysis of the Symptomatic Domains Most Relevant to Charcot Marie Tooth Neuropathy (CMT) Patients |
- Charcot Marie Tooth Disease (CMT)
- Hereditary Sensory and Motor Neuropathy
- Nerve Compression Syndromes
- (and 4 more...)
|
|
Observational |
|
- University of South Florida
- University of Rochester
- National Institute of Neurological Disorders and Stroke (NINDS)
|
Other / NIH |
- Observational Model: Cohort
- Time Perspective: Cross-Sectional
|
- Percentage of participants affected by specific symptoms of CMT.
- Severity of impact of each identified symptom of CMT
|
411 |
All |
18 Years and older (Adult, Senior) |
NCT02429947 |
INC6606
5U54NS064808-07 |
|
July 2012 |
June 2013 |
June 2013 |
April 29, 2015 |
June 14, 2017 |
|
- RDCRN Data Management and Coordinating Center , Epidemiology Center; University of South Florida
Tampa, Florida, United States
|
| 41 |
NCT00384007 |
Completed |
A Randomized Trial Comparing SpineJet® Hydrodiscectomy to Open Lumbar Microdiscectomy for Treatment of Lumbar Radiculopathy Due to Disc Herniation |
- Disc Herniation With Radiculopathy
|
- Procedure: Hydrodiscectomy with Spinejet
|
Interventional |
Not Applicable |
- Pinnacle Pain Medicine
- HydroCision, Inc.
|
Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
|
58 |
All |
18 Years to 75 Years (Adult, Senior) |
NCT00384007 |
HS-SJ-1001 |
|
October 2006 |
|
|
October 4, 2006 |
June 5, 2009 |
|
- Pinnacle Anesthesia Consultants, P.A. d.b.a. Pinnacle Pain Medicine
Dallas, Texas, United States
|
| 42 |
NCT02748395 |
Withdrawn |
Lidocaine and Triamcinolone vs Saline Trigger Point Injection for Treatment of Chronic Abdominal Wall Pain |
- Chronic Abdominal Wall Pain
- Abdominal Cutaneous Nerve Entrapment Syndrome
|
- Drug: Triamcinolone
- Other: Placebo
- Drug: Lidocaine
|
Interventional |
Phase 4 |
|
Other |
- Allocation: Randomized
- Intervention Model: Single Group Assignment
- Masking: Triple (Participant, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
|
0 |
All |
18 Years and older (Adult, Senior) |
NCT02748395 |
23417 |
|
May 2016 |
December 2016 |
|
April 22, 2016 |
December 5, 2016 |
|
|
| 43 |
NCT02553811 |
Completed |
Diagnosis of Carpal Tunnel Syndrome: Effectiveness of Diagnostic Tests. Clinical Trial of Accuracy |
- Carpal Tunnel Syndrome
- Compression Neuropathy, Carpal Tunnel
- Median Neuropathy, Carpal Tunnel
|
- Diagnostic Test: accuracy diagnostic
|
Interventional |
Not Applicable |
- Federal University of São Paulo
|
Other |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Diagnostic
|
- Accuracy of the ultrasonography (US)
- Accuracy of the electromyograph (EMG)
- Life quality
- Improvement in severity of symptoms and functional status of the patients
|
115 |
Female |
40 Years to 80 Years (Adult, Senior) |
NCT02553811 |
244468 |
DCTS |
October 2015 |
June 2016 |
October 2016 |
September 18, 2015 |
July 14, 2017 |
|
- Hospital Regional do Vale do Paraiba
Taubate, São Paulo, Brazil
|
| 44 |
NCT00681616 |
Unknown † |
Study of New Catheter & Pressure Monitor System to Help Prevent Compartment Syndrome From Developing in the Injured Leg |
|
- Device: Compartment Monitoring System (CMS)
- Device: Compartment Monitoring System with Active Fluid Removal
- Device: Compartment Monitoring System without fluid removal
|
Interventional |
Not Applicable |
- Twin Star Medical, Inc.
- United States Department of Defense
|
Industry / U.S. Fed |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Prevention
|
- To determine if use of Twin Star catheter with active fluid removal reduces muscle compartment pressure vs Twin Star catheter without fluid removal by comparing the randomized groups. Success will be defined by a p-value less than 0.05 (two-sided).
- Compares the treatment and control groups on change in perfusion pressure (defined as diastolic blood pressure minus IMP) over time. The randomized groups will be compared with a two-sided p-value less than 0.05 defining success.
|
90 |
All |
18 Years to 60 Years (Adult) |
NCT00681616 |
GE-4073
DoD Proposal:06275001
Award #:W81XWH-07-1-0243 |
TS2 |
January 2009 |
July 2010 |
December 2010 |
May 21, 2008 |
March 4, 2009 |
|
- University of California, Irvine Medical Center
Orange, California, United States - University of California - San Francisco / San Franciso General Hospital
San Francisco, California, United States - Denver Health Medical Center
Denver, Colorado, United States - (and 10 more...)
|
| 45 |
NCT02070302 |
Completed
Has Results |
BOTOX® (Onabotulinumtoxin A) Injection(s) as a Treatment for Carpal Tunnel Syndrome |
|
- Drug: Botulinum Toxin Type A
- Drug: Placebo
|
Interventional |
Phase 2 |
- Benjamin Sucher
- Allergan
- Arizona Arthritis & Rheumatology Research, PLLC.
|
Other / Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Participant, Investigator)
- Primary Purpose: Treatment
|
- Change From Baseline Levine Symptom Severity Scale Status at Weeks 6, 12,18.
- Change From Baseline Levine Function Severity Scale Status at Weeks 6, 12,18.
- Change From Baseline in Median Nerve Compression on Neuromuscular Ultrasound at Week 6, Week 12, and Week 18.
- (and 3 more...)
|
10 |
All |
18 Years and older (Adult, Senior) |
NCT02070302 |
85700 |
|
October 2014 |
February 2016 |
February 2016 |
February 25, 2014 |
September 27, 2017 |
September 27, 2017 |
- Arizona Arthritis & Rheumatology
Phoenix, Arizona, United States
|
| 46 |
NCT01753778 |
Completed |
Study Evaluating Treatment of Forefoot Pain Related to Nerve Entrapment Using the Cryo-Touch III Device |
|
- Device: Cryo-Touch III Device
|
Interventional |
Not Applicable |
|
Industry |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Improvement of forefoot pain at day 7
- Duration of Treatment
- Safety Endpoints
|
7 |
All |
18 Years and older (Adult, Senior) |
NCT01753778 |
MYO-0614 |
|
November 2012 |
May 2013 |
August 2013 |
December 20, 2012 |
January 29, 2014 |
|
- SOAR Medical Group
Redwood City, California, United States - International Clinical Research
Overland Park, Kansas, United States
|
| 47 |
NCT02600286 |
Recruiting |
Ulipristal Acetate In Disease Charcot-Marie-Tooth Type of 1A |
|
- Drug: EllaOne
- Drug: EllaOne placebo
|
Interventional |
Phase 2 |
- University Hospital, Strasbourg, France
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Triple (Participant, Care Provider, Investigator)
- Primary Purpose: Treatment
|
- Analysis of the effectiveness of Ellaone. This will be assessed by the production of RNA PMP22 using skin biopsy.
|
45 |
Male |
18 Years to 70 Years (Adult, Senior) |
NCT02600286 |
6100 |
UPACOMT |
October 23, 2015 |
October 23, 2018 |
October 23, 2018 |
November 9, 2015 |
May 17, 2017 |
|
- Département de Neurologie Centre de Référence des Maladies Neuromusculaires Grand Est (CERNEST) Hôpital de Hautepierre
Strasbourg, France
|
| 48 |
NCT00266214 |
Terminated |
Safety and Efficacy of Lidoderm (Lidocaine Patch 5%) in Treating Moderate to Severe Pain Associated With Carpal Tunnel Syndrome |
|
|
Interventional |
Phase 3 |
|
Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Participant, Investigator)
- Primary Purpose: Treatment
|
- Worst daily pain intensity score
- Average daily pain intensity score
- Levine CTS Symptom Severity and Functional Status Scales
- (and 4 more...)
|
210 |
All |
18 Years and older (Adult, Senior) |
NCT00266214 |
EN3272-301 |
|
November 2005 |
January 2007 |
January 2007 |
December 16, 2005 |
June 14, 2011 |
|
- PPD
Austin, Texas, United States
|
| 49 |
NCT02666443 |
Recruiting |
Low Dose Dexamethasone in Supraclavicular Blocks |
- Rheumatoid Arthritis
- Osteoarthritis
- Nerve Entrapment
- Ligament Injury
|
- Drug: Control intervention (no dexamethasone)
- Drug: Peri-neural Dexamethasone 1 mg
- Drug: Intravenous Dexamethasone 1 mg
|
Interventional |
Not Applicable |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Time to first sensation of pain at the surgical site.
- duration of motor blockade
- morphine or morphine equivalent usage in the first 48 h postoperatively
- (and 3 more...)
|
306 |
All |
18 Years to 80 Years (Adult, Senior) |
NCT02666443 |
REB13-1350 |
|
September 2016 |
February 2020 |
February 2021 |
January 28, 2016 |
September 7, 2016 |
|
- South Health Campus
Calgary, Alberta, Canada
|
| 50 |
NCT02115009 |
Unknown † |
The Sacroiliac Joint With SIJ Nerve Entrapments and Chronic Low Back Pain |
|
|
Observational |
|
- Carmel Medical Center
- Tel Aviv University
|
Other |
- Observational Model: Case Control
- Time Perspective: Prospective
|
- Percentage of the recruited participants
|
200 |
All |
20 Years to 50 Years (Adult) |
NCT02115009 |
CMC-13-0072-CTIL |
SARA31143 |
June 2014 |
December 2016 |
December 2017 |
April 15, 2014 |
May 6, 2014 |
|
|
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