60 studies found for:    Periventricular Leukomalacia
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Rank Status Study
21 Unknown  Magnesium Sulfate to Prevent Brain Injury in Premature Infants
Conditions: Brain Injuries;   Cerebral Palsy
Intervention: Drug: magnesium sulfate
22 Completed
Has Results
Fluconazole Prophylaxis for the Prevention of Candidiasis in Infants Less Than 750 Grams Birthweight
Condition: Candidiasis
Interventions: Drug: fluconazole;   Drug: placebo
23 Completed
Has Results
NIV Strategies for RDS in Preterm Infants. NIV (Non Invasive Ventilation), RDS (Respiratory Distress Syndrome)
Condition: RDS of Prematurity
Interventions: Device: NSIPPV;   Device: BiPAP
24 Active, not recruiting
Has Results
Surfactant Positive Airway Pressure and Pulse Oximetry Trial
Conditions: Infant, Newborn, Diseases;   Other Preterm Infants;   Infant, Small for Gestational Age;   Premature Birth;   Bronchopulmonary Dysplasia;   Retinopathy of Prematurity
Interventions: Drug: Surfactant;   Device: Continuous Positive Airway Pressure (CPAP);   Drug: Supplemental oxygen with target saturation of 85 to 89%;   Drug: Supplemental oxygen with target saturation of 91 to 95%
25 Completed Liberal Versus Restrictive Transfusion Guidelines for Preterm Infants
Conditions: Infant, Premature;   Anemia;   Intracranial Hemorrhages;   Leukomalacia, Periventricular;   Apnea
Intervention: Procedure: Red blood cell transfusion guidelines
26 Terminated
Has Results
Feasibility Study of Aerosolized Surfaxin in the Prevention of Respiratory Distress Syndrome (RDS) in Premature Infants
Condition: Respiratory Distress Syndrome
Intervention: Drug: Aerosolized lucinactant
27 Recruiting Indomethacin PK and PD Therapy in Pregnancy
Conditions: Premature Labor;   Pregnancy;   Premature Birth
28 Recruiting Maternal Omega-3 Supplementation to Reduce Bronchopulmonary Dysplasia
Conditions: Bronchopulmonary Dysplasia;   Child Development;   Neonatal and Perinatal Conditions
Interventions: Dietary Supplement: DHA-rich algal oil;   Dietary Supplement: Placebo
29 Completed Pentoxifylline and Late Onset Sepsis in Preterm Infants
Condition: Neonatal Late Onset Sepsis
Interventions: Drug: Pentoxifylline (PTX);   Drug: Placebo
30 Completed High Versus Low Dose of Caffeine for Apnea of Prematurity
Conditions: Apnea;   Preterm Infants
Intervention: Drug: Caffeine citrate
31 Enrolling by invitation The Effects of Probiotic Supplementation on Extremely Low Birthweight Infants
Condition: Feeding Tolerance
Interventions: Dietary Supplement: Probiotic Supplemented Group;   Dietary Supplement: Control Group
32 Completed Umbilical Cord Milking on the Reduction of Red Blood Cell Transfusion Rates in Infants
Condition: Prematurity
Intervention: Procedure: Umbilical Cord Milking
33 Terminated Delayed Umbilical Cord Clamping Versus Cord Milking in Preterm Neonate
Condition: Premature Birth
Interventions: Procedure: Delayed cord clamping;   Procedure: Milking of the cord
34 Completed Safety and Efficacy Study of Ibuprofen l-Lysine Solution in Premature Infants for Treatment of PDA
Condition: Patent Ductus Arteriosus
Intervention: Drug: ibuprofen l-lysine iv solution (NeoProfen (R) )
35 Completed Antenatal Betamethasone Compared to Dexamethasone - "BETACODE TRIAL"
Conditions: Respiratory Distress Syndrome;   Intraventricular Hemorrhage;   Neonatal Mortality
Intervention: Drug: Betamethasone(Celestone soluspan) and Dexamethasone
36 Unknown  Use of Blended Oxygen for Delivery Room Resuscitation of Very Low Birth Weight Infants
Conditions: Prematurity;   Oxidant Injury
Intervention: Procedure: Titration of oxygen in delivery room
37 Completed Consequences of Parenteral Nutrition Photoprotection on Oxidant Related Diseases Among Extremely Low Birth Weight Infants
Condition: Infant, Premature
Interventions: Device: photoprotected  bags,  tubing, syringes;   Device: standard tubing and bags
38 Completed Omega-3 Fatty Acid Supplementation to Prevent Preterm Birth in High Risk Pregnancies
Condition: Preterm Birth
Intervention: Drug: 17 alpha-Hydroxyprogesterone Caproate and Omega-3 fish oils
39 Completed Trial of Aggressive Versus Conservative Phototherapy in Infants <1,000 Grams Birth Weight
Conditions: Hyperbilirubinemia, Neonatal;   Jaundice, Neonatal;   Infant, Newborn;   Infant, Low Birth Weight;   Infant, Small for Gestational Age;   Infant, Premature
Interventions: Procedure: Aggressive Phototherapy 501-750g;   Procedure: Aggressive Phototherapy 751-1000g;   Procedure: Conservative Phototherapy 501-750g;   Procedure: Conservative Phototherapy 751-1000g
40 Terminated Minimal Breathing Support and Early Steroids to Prevent Chronic Lung Disease in Extremely Premature Infants (SAVE)
Conditions: Bronchopulmonary Dysplasia;   Respiratory Distress Syndrome;   Infant, Newborn;   Infant, Low Birth Weight;   Infant, Small for Gestational Age;   Infant, Premature
Interventions: Procedure: Minimal mechanical ventilation management;   Procedure: Routine mechanical ventilation management;   Drug: Dexamethasone;   Drug: Placebo

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Indicates status has not been verified in more than two years