2528 studies found for:    PD-1
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Rank Status Study
21 Recruiting Oligomeric Alpha-synuclein in Multiple System Atrophy
Condition: Multiple System Atrophy (MSA)
Intervention:
22 Recruiting A Phase II Study of Anti-PD-1 Antibody (MK-3475) in Relapsed/Refractory Chronic Lymphocytic Leukemia (CLL) and Other Low Grade B Cell Non-Hodgkin Lymphoma
Conditions: Chronic Lymphocytic Leukemia;   Other Low-grade B-cell Non-Hodgkin Lymphomas
Intervention: Biological: Pembrolizumab
23 Recruiting A Dose Escalation and Cohort Expansion Study of Anti-CD27 (Varlilumab) and Anti-PD-1 (Nivolumab) in Advanced Refractory Solid Tumors
Conditions: Non-small Cell Lung Cancer;   Melanoma;   Malignant Melanoma of Head and Neck;   Ovarian Carcinoma;   Colon Cancer
Intervention: Drug: Combination of varlilumab and nivolumab
24 Recruiting Study to Evaluate the Effectiveness, Safety and Tolerability of Nivolumab in Subjects With Advanced Liver Cancer Anti-PD-1 HCC (Anti-Programmed-Death-1 Hepatocellular Carcinoma)
Condition: Hepatocellular Carcinoma
Intervention: Biological: Nivolumab
25 Not yet recruiting Nivolumab in Treating Patients With Persistent, Recurrent, or Metastatic Cervical Cancer
Conditions: Cervical Adenocarcinoma;   Cervical Adenosquamous Carcinoma;   Cervical Squamous Cell Carcinoma;   Recurrent Cervical Carcinoma;   Stage IVA Cervical Cancer;   Stage IVB Cervical Cancer
Interventions: Biological: Nivolumab;   Other: Laboratory Biomarker Analysis
26 Withdrawn CT-011 and p53 Genetic Vaccine for Advanced Solid Tumors
Conditions: Breast Cancer;   Colon Cancer;   Pancreatic Cancer;   Sarcoma;   Ovarian Cancer
Interventions: Biological: p53: 264-272 peptide;   Drug: CT-011
27 Recruiting Study of REGN2810 (Anti-PD-1) in Patients With Advanced Malignancies
Condition: Advanced Malignancies
Interventions: Drug: REGN2810;   Radiation: Hypofractionated radiotherapy;   Drug: Cyclophosphamide
28 Recruiting Anti-PD-1 Monoclonal Antibody in Advanced, Trastuzumab-resistant, HER2-positive Breast Cancer
Condition: Metastatic Breast Cancer
Intervention: Drug: MK-3475
29 Active, not recruiting Phenylbutyrate Response as a Biomarker for Alpha-synuclein Clearance From the Brain
Condition: Parkinson's Disease
Intervention: Drug: Glycerol Phenylbutyrate
30 Recruiting Alpha-synuclein in Cerebrospinal Fluid to Differentiate Alzheimer's Disease From Lewy Body Disease.
Condition: "Alzheimer's Disease" and "Lewy Body Disease"
Interventions: Other: MRI;   Procedure: lumbar puncture;   Behavioral: neuropsychological tests
31 Recruiting Anti PD1 Antibody in Diffuse Intrinsic Pontine Glioma and Relapsed Glioblastoma Multiforme
Condition: Malignant Gliomas
Intervention: Biological: CT-011
32 Not yet recruiting Study of PDR001 in Patients With Advanced Malignancies
Conditions: Melanoma;   NSCLC;   Gastric Cancer;   Esophageal Adenocarcinoma;   Colorectal Cancer;   Anal Cancer;   Other Solid Tumors
Intervention: Biological: PDR001
33 Active, not recruiting PH 1 Biomarker Study of Nivolumab and Ipilimumab and Nivolumab in Combination With Ipilimumab in Advanced Melanoma
Conditions: Advanced Melanoma;   Metastatic Melanoma
Interventions: Biological: Nivolumab;   Drug: Ipilimumab
34 Not yet recruiting Pembrolizumab in Treating Patients With Malignant Mesothelioma
Conditions: Biphasic Mesothelioma;   Epithelioid Mesothelioma;   Peritoneal Malignant Mesothelioma;   Pleural Biphasic Mesothelioma;   Pleural Epithelioid Mesothelioma;   Pleural Malignant Mesothelioma;   Pleural Sarcomatoid Mesothelioma;   Recurrent Peritoneal Malignant Mesothelioma;   Recurrent Pleural Malignant Mesothelioma;   Sarcomatoid Mesothelioma
Interventions: Biological: Pembrolizumab;   Other: Laboratory Biomarker Analysis;   Other: Pharmacogenomic Study
35 Not yet recruiting Study of Pembrolizumab (MK-3475) Versus Placebo After Complete Resection of High-Risk Stage III Melanoma (MK-3475-054/KEYNOTE-054)
Condition: Melanoma
Interventions: Biological: pembrolizumab;   Other: placebo
36 Not yet recruiting Phase Ib and Phase II Studies of MK-3475 in Combination + for Renal Cell Carcinoma:
Condition: Clear Cell Renal Carcinoma
Interventions: Drug: MK-3475;   Drug: Bevacizumab
37 Recruiting Biomarkers in Parkinsonian Syndromes
Conditions: Parkinsonian Syndromes;   Parkinson's Disease;   Multiple System Atrophy;   Progressive Supranuclear Palsy
Interventions: Other: CSF, blood and urine sampling;   Other: clinical measures of disease severity and progression
38 Recruiting A Phase II Study of the Anti-PD1 Antibody Pembrolizumab (MK-3475) in Patients With Advanced Sarcomas
Conditions: Soft Tissue Sarcoma;   Bone Sarcoma
Intervention: Drug: Pembrolizumab
39 Unknown  Usefulness of α-synuclein as a Marker for Early Diagnosis of Parkinson's Disease in Skin Biopsy.
Conditions: Parkinson Disease;   Parkinsonian Disorders
Intervention: Procedure: Biopsy of skin
40 Recruiting Gemcitabine and CT-011 for Resected Pancreatic Cancer
Conditions: Pancreatic Neoplasms;   Cancer of the Pancreas;   Neoplasms Pancreatic;   Pancreatic Cancer;   Pancreas Cancer
Interventions: Biological: CT-011;   Drug: Gemcitabine

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Indicates status has not been verified in more than two years