44 studies found for:    OKT3
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Rank Status Study
1 Unknown  Oral OKT3 in Combination With Beta-D-Glucosylceramide
Condition: Healthy
Interventions: Drug: OKT3;   Drug: OKT3, GC;   Drug: GC
2 Unknown  Oral OKT3 for the Treatment of Active Ulcerative Colitis
Condition: Ulcerative Colitis
Intervention: Drug: Oral OKT3
3 Active, not recruiting Haploidentical Hematopoietic Stem Cell Transplantation Using A Novel Clofarabine Containing Conditioning Regimen For Patients With Refractory Hematologic Malignancies
Condition: Hematologic Malignancies
Interventions: Drug: Clofarabine;   Procedure: Stem Cell Transplantation, Hematopoietic;   Other: OKT3;   Drug: Thiotepa;   Drug: Melphalan;   Drug: Mycophenolate mofetil;   Drug: Rituximab;   Other: G-CSF
4 Completed Donor Peripheral Stem Cell Transplant and Donor Natural Killer Cell Transplant After Total-Body Irradiation, Thiotepa, Fludarabine, and Muromonab-CD3 in Treating Patients With Leukemia or Other Blood Diseases
Conditions: Graft Versus Host Disease;   Leukemia;   Myelodysplastic Syndromes
Interventions: Biological: muromonab-CD3;   Biological: natural killer cell therapy;   Drug: fludarabine phosphate;   Drug: methotrexate;   Drug: thiotepa;   Genetic: gene expression analysis;   Other: flow cytometry;   Other: immunologic technique;   Procedure: allogeneic hematopoietic stem cell transplantation;   Procedure: in vitro-treated peripheral blood stem cell transplantation;   Radiation: total-body irradiation
5 Completed Safety and Efficacy of Oral Administration of Anti-CD3 Monoclonal Antibody (mAb)in Patients With the Metabolic Syndrome
Condition: Nonalcoholic Steatohepatitis
Intervention: Drug: OKT3
6 Completed Study of Muromonab-CD3 and Cyclosporine in Patients With Giant Cell Myocarditis
Condition: Myocarditis
Interventions: Drug: Muromonab-CD3;   Drug: Cyclosporine
7 Completed Phase II Randomized Study of Muromonab-CD3, Cyclosporine, Methylprednisolone, and Prednisone in Patients With Giant Cell Myocarditis
Conditions: Myocarditis;   Giant Cell Myocarditis
Interventions: Drug: Cyclosporine;   Drug: methylprednisolone;   Drug: Muromonab-CD3;   Drug: prednisone
8 Unknown  Monoclonal Antibody Plus Cyclophosphamide in Treating Patients With Metastatic Cancer
Condition: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: Biological: antibody therapy;   Biological: biological therapy;   Biological: muromonab-CD3;   Drug: cyclophosphamide
9 Active, not recruiting HLA-Nonidentical Stem Cell and Natural Killer Cell Transplantation for Children Less the Two Years of Age With Hematologic Malignancies
Conditions: Acute Myeloid Leukemia;   Acute Lymphocytic Leukemia;   Myelodysplasia;   Chronic Myeloid Leukemia;   Histiocytosis
Interventions: Drug: Chemotherapy and antibodies;   Device: Miltenyi Biotec CliniMACS;   Procedure: Allogeneic stem cell transplantation
10 Completed Biological Therapy in Treating Women With Stage IV Breast Cancer
Condition: Breast Cancer
Interventions: Biological: Aldesleukin;   Biological: Sargramostim;   Biological: therapeutic autologous lymphocytes
11 Terminated Cultured White Cells Plus Interleukin-2 to Treat Advanced Kidney Cancer
Condition: Kidney Neoplasms
Interventions: Drug: IL-2 (interleukin-2);   Drug: OKT3;   Drug: Cyclophosphamide;   Drug: Fludarabine;   Drug: Mesna
12 Completed Vaccine Treatment in Combination With IL-2 and Treated Lymphocytes for Advanced Melanoma
Condition: Melanoma
Interventions: Drug: IL-2;   Drug: gp100:209-217;   Drug: OKT3;   Drug: rF-go 100P209;   Drug: Montanide ISA 51
13 Active, not recruiting Allogeneic Stem Cell Transplantation in Children and Adolescents With Acute Lymphoblastic Leukaemia
Condition: Lymphoblastic Leukemia, Acute, Childhood;
Interventions: Drug: VP16;   Radiation: TBI;   Drug: VP16, ATG;   Drug: Fludarabine, OKT3, Treosulfan, Thiotepa
14 Active, not recruiting ALL-SCT BFM International- HSCT in Children and Adolescents With ALL
Condition: Lymphoblastic Leukemia, Acute, Childhood;
Interventions: Drug: VP16;   Radiation: TBI;   Drug: VP16, ATG;   Drug: Fludarabine, OKT3, Treosulfan, Thiotepa
15 Recruiting Activated T Cells Armed With GD2 Bispecific Antibody in Children and Young Adults With Neuroblastoma and Osteosarcoma
Conditions: Desmoplastic Small Round Cell Tumor;   Disseminated Neuroblastoma;   Metastatic Childhood Soft Tissue Sarcoma;   Metastatic Ewing Sarcoma/PNET;   Metastatic Osteosarcoma;   Recurrent Adult Soft Tissue Sarcoma;   Recurrent Childhood Soft Tissue Sarcoma;   Recurrent Ewing Sarcoma/PNET;   Recurrent Melanoma;   Recurrent Neuroblastoma;   Recurrent Osteosarcoma
Interventions: Biological: IL-2;   Biological: GD2Bi-aATC;   Biological: GM-CSF;   Other: laboratory evaluations of immune responses
16 Completed Treated T Cells Followed by a Stem Cell Transplant in Treating Patients With Multiple Myeloma
Condition: Multiple Myeloma and Plasma Cell Neoplasm
Interventions: Biological: anti-CD3 x anti-CD20 bispecific antibody-armed activated T cells;   Procedure: autologous hematopoietic stem cell transplantation;   Procedure: peripheral blood stem cell transplantation
17 Completed Combination Chemotherapy Followed By Autologous Stem Cell Transplant, and White Blood Cell Infusions in Treating Patients With Non-Hodgkin's Lymphoma
Condition: Lymphoma
Interventions: Biological: therapeutic autologous lymphocytes;   Drug: carmustine;   Drug: cytarabine;   Drug: etoposide;   Drug: melphalan;   Procedure: peripheral blood stem cell transplantation (PBSCT)
18 Withdrawn Donor T Cells, Low-Dose Aldesleukin, and Low-Dose GM-CSF After Donor Stem Cell Transplant in Treating Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma
Condition: Lymphoma
Intervention: Biological: anti-CD3 x anti-CD20 bispecific antibody-armed activated T cells
19 Completed Twins Study of Gene Therapy for HIV Infection
Conditions: Acquired Immunodeficiency Syndrome;   HIV Infection;   Kaposi's Sarcoma
Intervention: Drug: Syngeneic Lymphocytes (CD4+) Cultured with OKT3 (Ortho) and Interleukin-2 (Chiro
20 Terminated Laboratory-Treated Autologous Lymphocytes, Aldesleukin, and Sargramostim (GM-CSF) in Treating Advanced Solid Tumors
Conditions: Neoplasms;   Tumors;   Solid Tumors;   Metastatic Cancer
Intervention: Biological: EGFRBi-armed autologous activated T cells

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Indicates status has not been verified in more than two years