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29 studies found for:    Multiple System Atrophy with Orthostatic Hypotension

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Multiple System Atrophy with Orthostatic Hypotension (29 records)
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Rank Status Study
1 Completed Efficacy of Therapeutic Interventions for Orthostatic Hypotension in Parkinson's Disease and Multiple System Atrophy
Conditions: Parkinson's Disease;   Multiple System Atrophy;   Orthostatic Hypotension
Interventions: Drug: Fludrocortisone;   Drug: Domperidone;   Behavioral: Conservative Measures for Orthostatic Hypotension
2 Recruiting Efficacy of L-threo DOPS on Orthostatic Hypotension Symptoms and Other Non-motor Symptoms in Patients With MSA
Condition: Multiple System Atrophy
Interventions: Drug: L-Threo DOPS;   Drug: placebo
3 Unknown † Fipamezole in Neurogenic Orthostatic Hypotension
Conditions: Symptomatic Neurogenic Orthostatic Hypotension (NOH);   Parkinson's Disease;   Multiple System Atrophy
Interventions: Drug: Placebo;   Drug: Fipamezole
4 Completed Norepinephrine Transporter Blockade as a Pathological Biomarker in Neurogenic Orthostatic Hypotension
Conditions: Orthostatic Hypotension;   Pure Autonomic Failure;   Multiple System Atrophy;   Parkinson's Disease
Intervention:
5 Completed
Has Results 		Open-Label Clinical Study of Droxidopa in Patients With Neurogenic Orthostatic Hypotension (NOH)
Conditions: Neurogenic Orthostatic Hypotension;   Non-Diabetic Autonomic Neuropathy;   Multiple System Atrophy;   Dopamine Beta Hydroxylase Deficiency
Interventions: Drug: Droxidopa;   Drug: Placebo
6 Recruiting Norepinephrine Transporter Blockade, Autonomic Failure
Condition: Multiple System Atrophy (MSA)
Interventions: Drug: Atomexetine;   Drug: Placebo
7 Completed
Has Results 		A Clinical Study for Patients With Neurogenic Orthostatic Hypotension (NOH) Using Droxidopa
Conditions: Symptomatic Neurogenic Orthostatic Hypotension (NOH);   Non-diabetic Neuropathy;   Primary Autonomic Failure;   Dopamine Beta Hydroxylase Deficiency
Interventions: Drug: Placebo;   Drug: Droxidopa
8 Completed Fluoxetine in Multiple System Atrophy Patients
Condition: Multiple System Atrophy
Intervention: Drug: FLUOXETINE
9 Completed
Has Results 		Clinical Study of Droxidopa in Patients With Neurogenic Orthostatic Hypotension (NOH)
Conditions: Symptomatic Neurogenic Orthostatic Hypotension (NOH);   Non-diabetic Neuropathy;   Primary Autonomic Failure;   Dopamine Beta Hydroxylase Deficiency
Interventions: Drug: Placebo;   Drug: Droxidopa
10 Recruiting Sustained Effect of Droxidopa in Symptomatic Neurogenic Orthostatic Hypotension
Condition: Symptomatic Neurogenic Orthostatic Hypotension
Interventions: Drug: Droxidopa capsules;   Drug: Placebo capsules
11 Unknown † Acetylcholinesterase Inhibition and Orthostatic Hypotension in SC I
Condition: Hypotension, Postural
Intervention: Drug: Pyridostigmine Bromide
12 Completed
Has Results 		A Study for Patients With Neurogenic Orthostatic Hypotension
Condition: Hypotension, Orthostatic
Intervention: Drug: Midodrine Hydrochloride
13 Recruiting Hemodynamic Mechanisms of Abdominal Compression in the Treatment of Orthostatic Hypotension in Autonomic Failure
Conditions: Orthostatic Hypotension;   Pure Autonomic Failure;   Multiple System Atrophy;   Autonomic Failure
Interventions: Other: Abdominal compression;   Other: Sham abdominal compression;   Drug: Placebo pill;   Drug: midodrine
14 Terminated A Phase IV Study in Subjects With Neurogenic Orthostatic Hypotension
Condition: Hypotension, Orthostatic
Intervention: Drug: midodrine hydrochloride (ProAmatine®)
15 Completed Droxidopa in Treating Patients With Neurogenic Hypotension
Conditions: Shy-Drager Syndrome;   Orthostatic Hypotension
Intervention: Drug: droxidopa
16 Recruiting Sporadic Degenerative Ataxia With Adult Onset: Natural History Study
Condition: Late Onset Sporadic Cerebellar Ataxia
Intervention:
17 Recruiting Natural History Study of Synucleinopathies
Condition: Patients With Synucleinopathies
Intervention:
18 Unknown † Investigation of the Serotoninergic System in Multiple System Atrophy: a Positron Emission Tomography (PET) Study
Condition: Multiple System Atrophy
Interventions: Radiation: PET (Positron Emission Tomography) Study;   Other: Brain MRI (magnetic resonance imaging);   Drug: Fluoxétine / Placebo
19 Recruiting Overnight Trials With Heat Stress in Autonomic Failure Patients With Supine Hypertension
Conditions: Hypertension;   Pure Autonomic Failure;   Multiple System Atrophy;   Autonomic Failure
Interventions: Device: Heating pad;   Device: Sham control
20 Recruiting Reduction in Splanchnic Capacitance Contributes to Sympathetically Dependent Hypertension in Autonomic
Conditions: Multiple System Atrophy;   Orthostatic Hypotension;   Supine Hypertension
Interventions: Drug: Trimethaphan;   Drug: Placebo
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† Study has passed its completion date and status has not been verified in more than two years.