47 studies found for:    MPDL3280A
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Rank Status Study
1 Not yet recruiting MPDL3280A-treatment-IST-UMCG
Conditions: Bladder Cancer;   Non Small Cell Lung Cancer;   Breast Cancer
Intervention: Drug: MPDL3280A
2 Not yet recruiting Preoperative MPDL3280A in Transitional Cell Carcinoma of the Bladder
Condition: Bladder Cancer
Intervention: Drug: MPDL3280A
3 Recruiting A Study of MPDL3280A Administered in Combination With Bevacizumab and/or With Chemotherapy in Participants With Locally Advanced or Metastatic Solid Tumors
Condition: Cancer
Interventions: Drug: Bevacizumab;   Drug: Carboplatin;   Drug: FOLFOX;   Drug: MPDL3280A;   Drug: Nab-paclitaxel;   Drug: Paclitaxel;   Drug: Pemetrexed
4 Not yet recruiting MPDL3280A-imaging-IST-UMCG
Conditions: Breast Cancer;   Bladder Cancer;   Non Small Cell Lung Cancer
Intervention: Other: 89Zr-MPDL-3280A-PET scans
5 Recruiting Triple-Negative First-Line Study: Neoadjuvant Trial of Nab-Paclitaxel and MPDL3280A, a Pdl-1 Inhibitor in Patients With Triple Negative Breast Cancer
Condition: Breast Cancer
Interventions: Drug: MPDL3280A;   Drug: Nab-paclitaxel
6 Recruiting MPDL3280A With Chemoradiation for Lung Cancer
Conditions: Lung Cancer;   Non-Small Cell Lung Cancer
Interventions: Drug: MPDL3280A;   Drug: Carboplatin;   Drug: Paclitaxel;   Radiation: Radiation Therapy
7 Recruiting A Pilot Study of MPDL3280A and HIGRT in Metastatic NSCLC
Condition: Non-small Cell Lung Cancer
Interventions: Drug: MPDL3280A;   Radiation: Hypofractionated Radiotherapy
8 Recruiting A Study to Assess the Safety and Tolerability of MPDL3280A in Combination With Other Immune-modulating Therapies in Patients With Locally Advanced or Metastatic Solid Tumors
Condition: Solid Cancers
Interventions: Drug: Interferon alfa-2b;   Drug: Ipilimumab;   Drug: MPDL3280A
9 Not yet recruiting MPDL3280A and Stereotactic Ablative Radiotherapy in Patients With Non-small Cell Lung Cancer
Conditions: Recurrent Non-Small Cell Lung Carcinoma;   Stage IV Non-Small Cell Lung Cancer
Interventions: Drug: Anti-PD-L1 Monoclonal Antibody MPDL3280A;   Radiation: Stereotactic Body Radiation Therapy
10 Not yet recruiting Study of MPDL3280A in Bladder Cancer
Condition: Carcinoma, Transitional Cell
Interventions: Drug: MPDL3280A Dose Level 1;   Drug: MPDL3280A Dose Level 2;   Drug: MPDL3280A Dose Level 3
11 Recruiting A Study of Atezolizumab (MPDL3280A) Compared With Gemcitabine + Cisplatin or Carboplatin in Patients With Stage IV Squamous Non-Small Cell Lung Cancer [IMpower111]
Condition: Non-Squamous Non-Small Cell Lung Cancer
Interventions: Drug: Atezolizumab (MPDL3280A);   Drug: Carboplatin;   Drug: Cisplatin;   Drug: Gemcitabine
12 Recruiting A Study of Intravenous RO6895882 and MPDL3280A Combination in Patients With Locally Advanced and/or Metastatic Solid Tumors
Condition: Solid Cancers
Interventions: Drug: MPDL3280A;   Drug: RO6895882
13 Recruiting A Study of RO7009789 in Combination With MPDL3280A in Patients With Locally Advanced and Metastatic Solid Tumors
Condition: Solid Cancers
Interventions: Drug: MPDL3280A;   Drug: RO7009789
14 Recruiting A Phase 1b Study of Atezolizumab (MPDL3280A, Anti-PD-L1 Antibody) in Combination With Vemurafenib or Vemurafenib Plus Cobimetinib in Participants With Previously Untreated BRAFV600-Mutation Positive Metastatic Melanoma
Condition: Malignant Melanoma
Interventions: Drug: Atezolizumab;   Drug: Cobimetinib;   Drug: Vemurafenib
15 Recruiting A Phase 1b/2 Study of Safety and Efficacy of Rociletinib in Combination With MPDL3280A in Patients With Advanced or Metastatic EGFR-mutant NSCLC
Condition: Non-small Cell Lung Cancer
Interventions: Drug: Rociletinib;   Drug: MPDL3280A
16 Recruiting A Single-Arm Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Immunogenicity, and Preliminary Efficacy of MPDL3280A (Anti-PD-L1 Antibody) in Pediatric and Young Adult Participants With Solid Tumors
Condition: Solid Tumor
Intervention: Drug: MPDL3280A
17 Not yet recruiting Phase 2 Study of MPDL3280A Combined With CDX-1401 in NY-ESO 1 (+) IIIB, IV or Recurrent Non-Small Cell Lung Cancer
Condition: Non-Small Cell Lung Cancer
Interventions: Drug: CDX-1401;   Drug: MPDL3280A
18 Recruiting A Phase 1b Study of MPDL3280A (an Engineered Anti-PDL1 Antibody) in Combination With Cobimetinib in Patients With Locally Advanced or Metastatic Solid Tumors
Condition: Neoplasms
Interventions: Drug: Cobimetinib;   Drug: MPDL3280A
19 Recruiting A Study of RO5509554 and MPDL3280A Administered in Combination in Patients With Advanced Solid Tumors
Condition: Solid Cancers
Interventions: Drug: MPDL3280A;   Drug: RO5509554
20 Recruiting A Study of Atezolizumab (MPDL3280A) in Combination With Epacadostat (INCB024360) in Subjects With Previously Treated Stage IIIB or Stage IV Non-Small Cell Lung Cancer
Condition: Non-small Cell Lung Cancer
Interventions: Drug: atezolizumab;   Drug: epacadostat

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Indicates status has not been verified in more than two years