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20 studies found for:    MK-4305
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Rank Status Study
1 Completed A Study to Evaluate Next Day Effects of MK-4305 on Driving Performance (MK-4305-035 AM1)
Condition: Insomnia
Interventions: Drug: MK-4305 40 mg;   Drug: MK-4305 20 mg;   Drug: Zopiclone;   Drug: Grossly Matching Placebo for Zopiclone;   Drug: Matching Placebo for MK-4305
2 Completed
Has Results
Safety and Efficacy Study of Suvorexant in Participants With Primary Insomnia - Study A (MK-4305-028)
Condition: Primary Insomnia
Interventions: Drug: Suvorexant High Dose (HD);   Drug: Suvorexant Low Dose (LD);   Drug: Comparator: Placebo
3 Completed
Has Results
Safety and Efficacy Study of Suvorexant in Participants With Primary Insomnia - Study B (MK-4305-029)
Condition: Primary Insomnia
Interventions: Drug: Suvorexant High Dose (HD);   Drug: Suvorexant Low Dose (LD);   Drug: Comparator: Placebo
4 Recruiting Safety and Efficacy of Suvorexant (MK-4305) for the Treatment of Insomnia in Participants With Alzheimer's Disease (MK-4305-061)
Conditions: Insomnia;   Alzheimer's Disease
Interventions: Drug: Suvorexant 10 mg;   Drug: Suvorexant 20 mg;   Drug: Placebo
5 Completed
Has Results
Pharmacokinetics of Suvorexant in Participants With Hepatic Insufficiency (MK-4305-017)
Conditions: Insomnia;   Hepatic Insufficiency
Intervention: Drug: Suvorexant
6 Completed
Has Results
Phase IIB 2-Period Crossover Polysomnography Study in Participants With Primary Insomnia (MK-4305-006)
Condition: Primary Insomnia
Interventions: Drug: Suvorexant;   Drug: Dose-matched Placebo to Suvorexant
7 Completed
Has Results
Effects of Suvorexant in Patients With Chronic Obstructive Pulmonary Disease (MK-4305-032)
Condition: Insomnia
Interventions: Drug: suvorexant;   Drug: Placebo
8 Completed
Has Results
Pharmacokinetics of Suvorexant in Participants With Impaired Renal Function (MK-4305-023)(COMPLETED)
Condition: Insomnia
Intervention: Drug: Suvorexant
9 Completed
Has Results
A Long Term Safety Study of Suvorexant in Participants With Primary Insomnia (MK-4305-009 AM3)
Condition: Insomnia
Interventions: Drug: Suvorexant;   Drug: Dose-matched Placebo to Suvorexant
10 Completed
Has Results
Effects of Suvorexant in Participants With Obstructive Sleep Apnea (MK-4305-036)
Condition: Sleep Apnea
Interventions: Drug: Suvorexant;   Drug: Matching Placebo
11 Recruiting A Pilot Study of Suvorexant for Insomnia in Parkinson Disease
Condition: Insomnia
Interventions: Drug: Suvorexant;   Drug: Placebo
12 Recruiting Suvorexant in Insomnia Co-morbid With Fibromyalgia
Conditions: Insomnia;   Fibromyalgia
Interventions: Drug: suvorexant;   Drug: placebo
13 Not yet recruiting To Compare the Effectiveness of Suvorexant vs Placebo on Sleep Pressure in Hypertensives With Insomnia
Conditions: Hypertension;   Insomnia
Interventions: Drug: suvorexant;   Other: Placebo
14 Recruiting Efficacy of Suvorexant to Treat Insomnia Related to Bipolar Disorder
Conditions: Insomnia;   Bipolar Disorder
Interventions: Drug: Suvorexant;   Drug: Placebo
15 Not yet recruiting A Six Week, Randomized, Double-Blind Placebo-Controlled, Suvorexant Augmentation Study of Antidepressant Treatment of Major Depressive Disorder With Residual Insomnia
Conditions: Depression;   Major Depressive Disorder;   MDD;   Insomnia
Interventions: Drug: suvorexant;   Drug: Placebo
16 Recruiting Suvorexant and Trauma Related Insomnia
Conditions: Insomnia;   Posttraumatic Stress Disorder
Interventions: Drug: suvorexant;   Other: placebo
17 Recruiting Role of the Orexin Receptor System in Stress, Sleep and Cocaine Use
Conditions: Cocaine Use Disorder;   Anxiety
Interventions: Drug: suvorexant;   Drug: Placebo (for suvorexant)
18 Not yet recruiting Suvorexant and Sleep's Benefits to Therapeutic Exposure for Posttraumatic Stress Disorder
Condition: Posttraumatic Stress Disorder
Interventions: Drug: suvorexant;   Other: placebo
19 Recruiting Examination of the Effectiveness of Suvorexant in Improving Daytime Sleep in Shift Workers
Condition: Sleep Disorder, Shift-Work
Interventions: Drug: Suvorexant;   Drug: Placebo
20 Recruiting The Role of Orexin in Human Panic Disorder
Condition: Panic Disorder
Interventions: Drug: suvorexant;   Drug: placebo

Indicates status has not been verified in more than two years