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31 studies found for:    Lennox-Gastaut Syndrome

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Rank Status Study
1 Unknown † Melatonin Versus Placebo in the Lennox-Gastaut Syndrome: Neurophysiological and Neuropsychological Effects
Condition: Lennox-Gastaut Syndrome
Interventions: Drug: melatonin;   Drug: placebo
2 Completed
Has Results 		Transcranial Direct Current Stimulation, Treatment of Childhood Drug-Resistant Lennox-Gastaut Syndrome, A Pilot Study
Condition: Lennox-Gastaut Syndrome
Intervention: Device: tDCS
3 Not yet recruiting Study of Perampanel as Adjunctive Treatment for Inadequately Controlled Seizures Associated With Lennox-Gastaut Syndrome
Condition: Lennox-Gastaut Syndrome (LGS)
Interventions: Drug: Perampanel;   Drug: Placebo
4 Completed European Registry of Anti-Epileptic Drug Use in Patients With Lennox-Gastaut Syndrome (LGS)
Condition: Lennox-Gastaut Syndrome
Intervention:
5 Completed
Has Results 		Safety and Effectiveness of Open-Label Clobazam in Subjects With Lennox-Gastaut Syndrome
Condition: Lennox-Gastaut Syndrome
Intervention: Drug: Clobazam
6 Completed
Has Results 		A Placebo-Controlled, Double-Blind Comparative Study of E2080 in Lennox-Gastaut Syndrome Patients (Study E2080-J081-304)
Condition: Lennox-Gastaut Syndrome
Interventions: Drug: Rufinamide (E2080);   Drug: Placebo
7 Enrolling by invitation An Open Label Extension Study of Cannabidiol (GWP42003-P) in Children and Young Adults With Dravet or Lennox-Gastaut Syndromes
Conditions: Epilepsy;   Dravet Syndrome;   Lennox-Gastaut Syndrome
Intervention: Drug: GWP42003-P
8 Active, not recruiting A Study to Investigate the Efficacy and Safety of Cannabidiol (GWP42003-P; CBD) as Adjunctive Treatment for Seizures Associated With Lennox-Gastaut Syndrome in Children and Adults
Conditions: Epilepsy;   Lennox-Gastaut Syndrome
Interventions: Drug: GWP42003-P;   Drug: Placebo Control
9 Active, not recruiting A Study to Investigate the Efficacy and Safety of Cannabidiol (GWP42003-P; CBD) as Adjunctive Treatment for Seizures Associated With Lennox-Gastaut Syndrome in Children and Adults
Conditions: Epilepsy;   Lennox-Gastaut Syndrome
Interventions: Drug: GWP42003-P;   Drug: Placebo control
10 Completed Study of Rufinamide in Pediatric Subjects 1 to Less Than 4 Years of Age With Lennox-Gastaut Syndrome Inadequately Controlled With Other Anti-epileptic Drugs
Condition: Lennox-Gastaut Syndrome
Interventions: Drug: Rufinamide;   Drug: Any other approved AED
11 Not yet recruiting Cannabidiol Oral Solution as an Adjunctive Therapy for Treatment of Subjects With Inadequately Controlled Lennox-Gastaut Syndrome
Condition: Lennox-Gastaut Syndrome
Interventions: Drug: Cannabidiol Oral Solution;   Drug: Placebo Solution
12 Completed Phase III Randomized, Double-Blind, Placebo-Controlled Study of Oral Topiramate for Lennox-Gastaut Syndrome
Condition: Lennox-Gastaut Syndrome
Intervention: Drug: topiramate
13 Completed
Has Results 		Clobazam in Patients With Lennox-Gastaut Syndrome
Conditions: Epilepsy;   Epilepsy, Generalized;   Seizures
Interventions: Drug: Clobazam Low Dose;   Drug: Clobazam Medium Dose;   Drug: Clobazam High Dose;   Drug: Placebo
14 Completed A Study of the Efficacy and Safety of Topiramate as an add-on Therapy in the Treatment of Epilepsy Patients With Lennox-Gastaut Syndrome
Conditions: Epilepsy;   Seizures
Intervention: Drug: topiramate
15 Recruiting Trial to Assess Vagus Nerve Stimulation Therapy in Children With Lennox-Gastaut Syndrome
Condition: Lennox-Gastaut Syndrome
Intervention: Device: PINS Vagus Nerve Stimulator
16 Completed
Has Results 		Clobazam in Subjects With Lennox-Gastaut Syndrome
Conditions: Epilepsy;   Epilepsy, Generalized;   Seizures
Interventions: Drug: Clobazam Low Dose;   Drug: Clobazam High Dose
17 Not yet recruiting The Pharmacokinetics of Cannabidiol (CBD) and Its Effects in Children With Severe Epilepsy
Conditions: Dravet Syndrome;   Lennox Gastaut Syndrome
Intervention:
18 Completed Ketogenic Diet for Child Epilepsy and Seizure Control
Conditions: Epilepsy;   Seizures;   Lennox-Gastaut Syndrome
Intervention: Behavioral: Ketogenic diet
19 Terminated
Has Results 		Long-term, Open-label Safety Extension Study of Retigabine/Ezogabine in Pediatric Subjects (>= 12 Years Old) With POS or LGS
Condition: Epilepsy
Intervention: Drug: retigabine/ezogabine
20 Completed A Study of the Safety of Topiramate Given in Combination With Other Medications in Adults and Children With Seizures
Conditions: Seizures;   Epilepsy
Intervention: Drug: Topiramate
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† Indicates status has not been verified in more than two years