Comment Period Extended to 3/23/2015 for Notice of Proposed Rulemaking (NPRM) for FDAAA 801 and NIH Draft Reporting Policy for NIH-Funded Trials
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25 studies found for:    Lennox-Gastaut Syndrome

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Rank Status Study
1 Unknown † Melatonin Versus Placebo in the Lennox-Gastaut Syndrome: Neurophysiological and Neuropsychological Effects
Condition: Lennox-Gastaut Syndrome
Interventions: Drug: melatonin;   Drug: placebo
2 Active, not recruiting European Registry of Anti-Epileptic Drug Use in Patients With Lennox-Gastaut Syndrome (LGS)
Condition: Lennox-Gastaut Syndrome
Intervention:
3 Completed
Has Results 		Safety and Effectiveness of Open-Label Clobazam in Subjects With Lennox-Gastaut Syndrome
Condition: Lennox-Gastaut Syndrome
Intervention: Drug: Clobazam
4 Completed
Has Results 		A Placebo-Controlled, Double-Blind Comparative Study of E2080 in Lennox-Gastaut Syndrome Patients (Study E2080-J081-304)
Condition: Lennox-Gastaut Syndrome
Interventions: Drug: Rufinamide (E2080);   Drug: Placebo
5 Not yet recruiting An Open Label Extension Study of Cannabidiol (GWP42003-P) in Children and Young Adults With Dravet or Lennox-Gastaut Syndromes
Conditions: Epilepsy;   Dravet Syndrome;   Lennox-Gastaut Syndrome
Intervention: Drug: GWP42003-P
6 Not yet recruiting A Study to Investigate the Efficacy and Safety of Cannabidiol (GWP42003-P; CBD) as Adjunctive Treatment for Seizures Associated With Lennox-Gastaut Syndrome in Children and Adults
Conditions: Epilepsy;   Lennox-Gastaut Syndrome
Interventions: Drug: GWP42003-P;   Drug: Placebo control
7 Not yet recruiting A Study to Investigate the Efficacy and Safety of Cannabidiol (GWP42003-P; CBD) as Adjunctive Treatment for Seizures Associated With Lennox-Gastaut Syndrome in Children and Adults
Conditions: Epilepsy;   Lennox-Gastaut Syndrome
Interventions: Drug: GWP42003-P;   Drug: Placebo Control
8 Active, not recruiting Study of Rufinamide in Pediatric Subjects 1 to Less Than 4 Years of Age With Lennox-Gastaut Syndrome Inadequately Controlled With Other Anti-epileptic Drugs
Condition: Lennox-Gastaut Syndrome
Interventions: Drug: Rufinamide;   Drug: Any other approved AED
9 Not yet recruiting Cannabidiol Oral Solution as an Adjunctive Therapy for Treatment of Subjects With Inadequately Controlled Lennox-Gastaut Syndrome
Condition: Lennox-Gastaut Syndrome
Interventions: Drug: Cannabidiol Oral Solution;   Drug: Placebo Solution
10 Completed Phase III Randomized, Double-Blind, Placebo-Controlled Study of Oral Topiramate for Lennox-Gastaut Syndrome
Condition: Lennox-Gastaut Syndrome
Intervention: Drug: topiramate
11 Completed
Has Results 		Clobazam in Patients With Lennox-Gastaut Syndrome
Conditions: Epilepsy;   Epilepsy, Generalized;   Seizures
Interventions: Drug: Clobazam Low Dose;   Drug: Clobazam Medium Dose;   Drug: Clobazam High Dose;   Drug: Placebo
12 Completed A Study of the Efficacy and Safety of Topiramate as an add-on Therapy in the Treatment of Epilepsy Patients With Lennox-Gastaut Syndrome
Conditions: Epilepsy;   Seizures
Intervention: Drug: topiramate
13 Completed
Has Results 		Clobazam in Subjects With Lennox-Gastaut Syndrome
Conditions: Epilepsy;   Epilepsy, Generalized;   Seizures
Interventions: Drug: Clobazam Low Dose;   Drug: Clobazam High Dose
14 Completed Ketogenic Diet for Child Epilepsy and Seizure Control
Conditions: Epilepsy;   Seizures;   Lennox-Gastaut Syndrome
Intervention: Behavioral: Ketogenic diet
15 Completed A Study of the Safety of Topiramate Given in Combination With Other Medications in Adults and Children With Seizures
Conditions: Seizures;   Epilepsy
Intervention: Drug: Topiramate
16 Terminated
Has Results 		Long-term, Open-label Safety Extension Study of Retigabine/Ezogabine in Pediatric Subjects (>= 12 Years Old) With POS or LGS
Condition: Epilepsy
Intervention: Drug: retigabine/ezogabine
17 Recruiting Post-marketing Surveillance of Long-term Administration of Inovelon Tablets in Patients With Lennox-Gastaut Syndrome
Condition: Lennox-Gastaut Syndrome
Intervention: Drug: Rufinamide
18 Active, not recruiting Epilepsy Phenome/Genome Project
Conditions: Epilepsy;   Localization-related Epilepsy;   Infantile Spasms;   Lennox-Gastaut Syndrome;   Polymicrogyria;   Periventricular Heterotopias
Intervention:
19 Completed A Long Term Extension Study of E2080 in Lennox-Gastaut Patients
Condition: Lennox-Gastaut Syndrome
Intervention: Drug: E2080
20 Not yet recruiting Cannabidiol Oral Solution as an Adjunctive Treatment for Treatment-resistant Seizure Disorder
Condition: Seizures
Intervention: Drug: Cannabidiol Oral Solution
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† Indicates status has not been verified in more than two years