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130 studies found for:    Immunodeficiency NOT AIDS | Open Studies
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Rank Status Study
21 Recruiting Establishing Fibroblast-Derived Cell Lines From Skin Biopsies of Patients With Immunodeficiency or Immunodysregulation Disorders
Conditions: Lymphohistiocytosis, Hemophagocytic;   Common Variable Immunodeficiency;   Severe Combined Immunodeficiency
Intervention:
22 Recruiting Immune Regulation in Patients With Common Variable Immunodeficiency and Related Syndromes
Condition: CVID
Intervention:
23 Recruiting Study to Investigate Efficacy, Safety and Pharmacokinetics of BT595 in Subjects With PID
Condition: Immunodeficiency Primary
Intervention: Biological: BT595
24 Not yet recruiting Post-Authorization Safety, Tolerability and Immunogenicity Evaluation of HyQvia in Pediatric PIDD Subjects
Condition: Primary Immunodeficiency Diseases (PID)
Interventions: Biological: HYQVIA;   Biological: KIOVIG;   Biological: Cuvitru
25 Recruiting Allogeneic Hematopoietic Stem Cell Transplant for Patients With Primary Immune Deficiencies
Conditions: SCID;   Omenn's Syndrome;   Reticular Dysgenesis;   Wiskott-Aldrich Syndrome;   Bare Lymphocyte Syndrome;   Common Variable Immunodeficiency;   Chronic Granulomatous Disease;   CD40 Ligand Deficiency;   Hyper IgM Syndrome;   X-linked Lymphoproliferative Disease;   Hemophagocytic Lymphohistiocytosis;   Griscelli Syndrome;   Chediak-Higashi Syndrome;   Langerhan's Cell Histiocytosis
Interventions: Drug: Alemtuzumab 0.3 mg;   Drug: Cyclophosphamide;   Drug: Busulfan;   Biological: Stem Cell Transplantation;   Drug: Fludarabine phosphate 40 mg;   Drug: Melphalan;   Drug: Alemtuzumab 0.2 mg;   Drug: Fludarabine phosphate 30 mg;   Drug: MESNA
26 Recruiting Gene Transfer for Severe Combined Immunodeficiency, X-linked (SCID-X1) Using a Self-inactivating (SIN) Gammaretroviral Vector
Condition: Severe Combined Immunodeficiency
Intervention: Biological: Gene transfer
27 Not yet recruiting Improving the Diagnosis of Common Variable Immune Deficiency
Condition: Common Variable Immune Deficiency (CVID)
Intervention:
28 Recruiting TCR Alpha/Beta Depletion for HSCT From Haploidentical and Unrelated Donors in the Treatment of PID
Conditions: Primary Immune Deficiency Disorder;   Hematopoietic Stem Cell Transplantation
Intervention: Other: Biological: TCR alfa beta T cell depletion
29 Not yet recruiting Clinical Trial to Assess the Efficacy of Rituximab and Azathioprine in the Treatment of Granulomatous and Lymphocytic Interstitial Lung Disease (GLILD) in Adult Patients With Common Variable Immunodeficiency (CVID)
Condition: Granulomatous and Lymphocytic Interstitial Lung Disease
Interventions: Drug: Rituximab (RTX) and Azathioprine (AZA);   Drug: Placebo Administration
30 Recruiting EZN-2279 in Patients With ADA-SCID
Conditions: ADA-SCID;   Adenosine Deaminase Deficiency;   Severe Combined Immunodeficiency
Interventions: Biological: EZN-2279;   Biological: Adagen
31 Recruiting Autologous Cryopreserved CD34+ Hematopoietic Cells Transduced With EFS-ADA Lentivirus for ADA SCID
Condition: Severe Combined Immunodeficiency Due to ADA Deficiency
Intervention: Biological: Infusion of autologous cryopreserved EFS-ADA LV CD34+ cells
32 Recruiting Study of Efficacy of CDZ173 in Patients With APDS/PASLI
Condition: Activated PI3Kdelta Syndrome (APDS); p110delta-activating Mutation Causing Senescent T Cells, Lymphadenopathy and Immunodeficiency (PASLI)
Intervention: Drug: CDZ173
33 Recruiting A Phase 3, Multinational, Multicenter, Open-Label Study of ProMetic BioTherapeutics IVIG
Condition: Primary Immunodeficiency
Interventions: Biological: Immune Globulin (Human) Intravenous;   Biological: Commercial Immune Globulin Intravenous
34 Available Expanded Access Protocol Thymus Transplantation
Conditions: Poor Thymic Function;   Immunodeficiency;   Athymia;   Immunoreconstitution;   Thymus Transplantation;   Low T Cell Numbers
Interventions: Biological: Thymus Transplantation;   Procedure: Blood Draw;   Drug: Rabbit Anti-Thymocyte Globulin and Cyclosporine or Tacrolimus
35 Recruiting Study of Octanorm Subcutaneous IG in Patients With PID
Condition: Primary Immune Deficiency Disorder
Intervention: Biological: octanorm 16.5%
36 Available cliniMACs HUD for T Cell Depletion
Condition: x Linked Combined Immunodeficiency
Intervention: Device: CliniMACs
37 Recruiting Octagam 5% Versus Comparator Post Marketing Trial
Condition: Primary Immune Deficiency Disorder
Interventions: Biological: Octagam 5%;   Biological: Other marketed IVIG product
38 Recruiting Sequential Cadaveric Lung and Bone Marrow Transplant for Immune Deficiency Diseases
Conditions: Severe Combined Immunodeficiency (SCID);   Immunodeficiency With Predominant T-cell Defect, Unspecified;   Severe Chronic Neutropenia;   Chronic Granulomatous Disease (CGD);   Hyper IgE Syndromes;   Hyper IgM Deficiencies;   Wiskott-Aldrich Syndrome;   Mendelian Susceptibility to Mycobacterial Disease;   Common Variable Immune Deficiency (CVID)
Intervention: Biological: CD3/CD19 negative allogeneic hematopoietic stem cells
39 Recruiting Magnesium Supplementation in People With XMEN Syndrome
Conditions: X-linked Immunodeficiency With Magnesium Defect;   Epstein-Barr Virus (EBV) Infection and Neoplasia
Interventions: Drug: Magnesium L-threonate;   Drug: Placebo;   Drug: Magnesium Sulfate (MgSO)
40 Recruiting Screening Protocol for Genetic Diseases of Lymphocyte Homeostasis and Programmed Cell Death
Condition: Primary Immune Deficiency
Intervention:

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Study has passed its completion date and status has not been verified in more than two years.