Comment Period Extended to 3/23/2015 for Notice of Proposed Rulemaking (NPRM) for FDAAA 801 and NIH Draft Reporting Policy for NIH-Funded Trials
2392 studies found for:    Immunodeficiency
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Rank Status Study
21 Active, not recruiting Gene Therapy for X-linked Severe Combined Immunodeficiency
Condition: X-linked Severe Combined Immunodeficiency
Intervention: Other: Gene transfer
22 Withdrawn A Study to Assess the Safety and Effectiveness of Darunavir for Treating Human Immunodeficiency Virus-Type I (HIV-1) Infection in Filipino Patients
Condition: Human Immunodeficiency Virus-Type 1
Intervention: Drug: No intervention
23 Completed Efficacy and Safety of Intravenous Immunoglobulin IVIG-F10 in Patients With Primary Immunodeficiencies (PID)
Conditions: Agammaglobulinemia;   IgG Deficiency;   Common Variable Immunodeficiency
Intervention: Drug: Immunoglobulins Intravenous (Human)
24 Completed Efficacy and Safety of Intravenous Immunoglobulin IgPro10 in Patients With Primary Immunodeficiencies (PID)
Conditions: Agammaglobulinemia;   IgG Deficiency;   Common Variable Immunodeficiency
Intervention: Drug: Immunoglobulins Intravenous (Human)
25 Active, not recruiting Diagnosis and Treatment of Co-infection With Human Immunodeficiency Virus /Latent Tuberculosis Infection (HIV/TBL)
Conditions: Human Immunodeficiency Virus (HIV);   Tuberculosis (TB);   Latent Tuberculosis Infection (LTI)
Intervention: Drug: Isoniazid
26 Not yet recruiting Generalized Neonatal Screening of Severe Combined Immunodeficiencies
Condition: Severe Combined Immunodeficiency, Atypical
Intervention: Biological: SCID screening
27 Completed Transplantation of Hematopoietic Cells in Children With Severe Combined Immunodeficiency Syndrome
Condition: Severe Combined Immunodeficiency
Interventions: Procedure: Stem cell transplant;   Drug: Filgrastim, Alemtuzumab;   Device: Miltenyi CliniMACS
28 Completed Immune System and Gut Abnormalities in Patients With Common Variable Immunodeficiency With and Without Gastrointestinal Symptoms
Condition: Common Variable Immunodeficiency
Intervention:
29 Withdrawn A Study on the Safety and Effectiveness of Rilpivirine Hydrochloride (Edurant) Among Adult Filipino Patients With Human Immunodeficiency Virus Type-I Infection
Condition: Human Immunodeficiency Virus Type 1 (HIV-1) Infection
Intervention: Drug: No intervention
30 Not yet recruiting Clinical Characteristics and Genetic Profiles of Severe Combined Immunodeficiency in China
Condition: Severe Combined Immunodeficiency
Intervention: Genetic: gene sequencing
31 Completed STA-5326 Meslylate to Treat Gut Inflammation Associated With Common Variable Immunodeficiency
Condition: Common Variable Immunodeficiency
Intervention: Drug: STA-5326
32 Completed Safety and Efficacy Study of a 10% Intravenous Immune Globulin Solution in Subjects With Primary Immunodeficiency Disorders
Conditions: Primary Immunodeficiency Disorders;   Immune Thrombocytopenic Purpura (ITP);   Kawasaki Syndrome
Intervention: Procedure: Immune Globulin Intravenous (Human), 10%
33 Terminated Allogeneic Bone Marrow Transplantation in Patients With Primary Immunodeficiencies
Conditions: Immunologic Deficiency Syndromes;   Chediak-Higashi Syndrome;   Common Variable Immunodeficiency;   Graft Versus Host Disease;   X-Linked Lymphoproliferative Syndrome;   Familial Erythrophagocytic Lymphohistiocytosis;   Hemophagocytic Lymphohistiocytosis;   X-linked Agammaglobulinemia;   Wiskott-Aldrich Syndrome;   Chronic Granulomatous Disease;   X-linked Hyper IgM Syndrome;   Severe Combined Immunodeficiency;   Leukocyte Adhesion Deficiency Syndrome;   Virus-Associated Hemophagocytic Syndrome
Interventions: Drug: anti-thymocyte globulin;   Drug: busulfan;   Drug: cyclophosphamide;   Drug: cyclosporine;   Drug: etoposide;   Drug: methotrexate;   Drug: methylprednisolone;   Drug: prednisone;   Procedure: Allogeneic Bone Marrow Transplantation
34 Completed Human Immunodeficiency Virus (HIV) Postexposure Prophylaxis (PEP) With Darunavir/Ritonavir (DRV/r)
Condition: Human Immunodeficiency Virus (HIV)
Interventions: Drug: Darunavir/Ritonavir (DRV/r);   Drug: Lopinavir in fixed combination with Ritonavir;   Drug: Zidovudine;   Drug: NRTIs;   Drug: Efavirenz
35 Active, not recruiting Efficacy and Safety Study of Kedrion IVIG 10% to Treat Subjects With Primary Immunodeficiency (PID)
Conditions: Primary Immunodeficiency;   Agammaglobulinemia;   Hypogammaglobulinemia;   Antibody Deficiency
Intervention: Biological: Kedrion IVIG 10%
36 Recruiting Gamma Globulin Observations and Outcomes Database for Patients With Primary Immunodeficiency Disease (GOOD-SHEPARD-PI)
Condition: Primary Immune Deficiency Disorder
Intervention: Other: Immunoglobulin Therapy
37 Unknown  "Prime Boost" Vaccination Strategy Combining Conjugated Anti- Pneumococcal Vaccine (s0) and Polysaccharide Anti- Pneumococcal Vaccine (s4) Compared to Polysaccharide Anti- Pneumococcal Vaccine Alone (s4) In Patients With Common Variable Immunodeficiency
Condition: Common Variable Immunodeficiency
Interventions: Biological: PPS;   Biological: PnCJ PPS
38 Completed
Has Results
A Study to Find Out How Safe and Effective Gammaplex® is in Young People With Primary Immunodeficiency
Conditions: Primary Immune Deficiency Disorders;   Common Variable Immunodeficiency;   X-linked Agammaglobulinemia;   Hyper-IgM Syndrome;   Wiskott-Aldrich Syndrome
Intervention: Biological: Gammaplex
39 Completed Treatment for Growth Failure in Patients With X-Linked Severe Combined Immunodeficiency: Phase 2 Study of Insulin-Like Growth Factor-1
Conditions: Growth Failure;   X-linked Severe Combined Immunodeficiency (XSCID);   Growth Hormone Resistence
Interventions: Drug: Increlex;   Procedure: Arginine Provocation Test;   Procedure: Clonidine Provocation Test;   Procedure: IGF-1 Generation Test;   Drug: IVIG;   Procedure: Haplo-Identical Bone Marrow Transplant
40 Completed
Has Results
A Study of the Once Daily Combination of Etravirine and Darunavir/Ritonavir As Dual Therapy in Early Treatment-Experienced Patients
Condition: Human Immunodeficiency Virus (HIV)
Interventions: Drug: Etravirine;   Drug: Ritonavir;   Drug: Darunavir

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Indicates status has not been verified in more than two years