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63 studies found for:    Holden Comprehensive Cancer Center | Open Studies
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Study Details
Participant Details
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Rank Status Study
1 Recruiting A Phase 2 Trial of High-Dose Ascorbate in Glioblastoma Multiforme
Condition: Glioblastoma Multiforme
Interventions: Drug: Temozolomide;   Radiation: radiation therapy;   Drug: Ascorbic Acid
2 Not yet recruiting Study to Evaluate the Safety of Combining Two Radionuclide Therapies to Treat Mid-gut Neuroendocrine Tumors
Conditions: Neuroendocrine Tumor, Malignant;   Neuroendocrine Tumor Gastrointestinal, Hormone-Secreting
Interventions: Drug: 90Y-DOTA-3-Tyr-Octreotide;   Drug: 131I-MIBG
3 Recruiting Pharmacological Ascorbate for Lung Cancer
Condition: Carcinoma, Non-Small-Cell Lung
Interventions: Drug: Paclitaxel;   Drug: Carboplatin;   Drug: Ascorbic Acid
4 Recruiting Dose Escalation Phase I/II Study of Lovastatin With High-Dose Cytarabine for Refractory or Relapsed AML
Condition: Acute Myeloid Leukemia
Intervention: Drug: Lovastatin and Cytarabine
5 Recruiting Decitabine and Gemcitabine for Pancreatic Cancer and Sarcoma
Conditions: Pancreatic Ductal Adenocarcinoma;   Sarcoma
Interventions: Drug: Decitabine;   Drug: Gemcitabine
6 Recruiting Rituximab With or Without Yttrium Y-90 Ibritumomab Tiuxetan in Treating Patients With Untreated Follicular Lymphoma
Conditions: Stage I Grade 1 Follicular Lymphoma;   Stage I Grade 2 Follicular Lymphoma;   Stage II Grade 1 Contiguous Follicular Lymphoma;   Stage II Grade 1 Non-Contiguous Follicular Lymphoma;   Stage II Grade 2 Contiguous Follicular Lymphoma;   Stage II Grade 2 Non-Contiguous Follicular Lymphoma;   Stage III Grade 1 Follicular Lymphoma;   Stage III Grade 2 Follicular Lymphoma;   Stage IV Grade 1 Follicular Lymphoma;   Stage IV Grade 2 Follicular Lymphoma
Interventions: Other: Laboratory Biomarker Analysis;   Other: Quality-of-Life Assessment;   Biological: Rituximab;   Radiation: Yttrium Y-90 Ibritumomab Tiuxetan
7 Not yet recruiting A Phase 2 Trial of High-dose Ascorbate for Pancreatic Cancer
Conditions: Pancreatic Neoplasms;   Cancer of Pancreas;   Cancer of the Pancreas;   Neoplasms, Pancreatic;   Pancreas Cancer;   Pancreas Neoplasms;   Adenocarcinoma
Interventions: Drug: Gemcitabine;   Drug: nab-paclitaxel;   Drug: Ascorbic Acid
8 Not yet recruiting A Phase 2 Study Adding Ascorbate to Chemotherapy and Radiation Therapy for NSCLC
Conditions: Carcinoma, Non-Small-Cell Lung;   Non-Small Cell Lung Cancer;   Nonsmall Cell Lung Cancer;   Non-Small-Cell Lung Carcinoma;   NSCLC
Interventions: Drug: Radiation Therapy;   Drug: Paclitaxel;   Drug: Carboplatin;   Drug: Ascorbic Acid
9 Not yet recruiting Retinoid 9cUAB30 in Producing a Biologic Effect in Patients With Early Stage Breast Cancer
Conditions: Early-Stage Breast Carcinoma;   Estrogen Receptor Negative;   Estrogen Receptor Positive;   Grade 2 Invasive Breast Carcinoma;   Grade 3 Invasive Breast Carcinoma;   HER2/Neu Negative;   HER2/Neu Positive
Interventions: Other: Laboratory Biomarker Analysis;   Drug: Retinoid 9cUAB30;   Procedure: Therapeutic Conventional Surgery
10 Recruiting Cholecalciferol in Improving Survival in Patients With Newly Diagnosed Cancer With Vitamin D Insufficiency
Conditions: Aggressive Non-Hodgkin Lymphoma;   Anaplastic Large Cell Lymphoma;   Angioimmunoblastic T-Cell Lymphoma;   Chronic Lymphocytic Leukemia;   Diffuse Large B-Cell Lymphoma;   Enteropathy-Associated T-Cell Lymphoma;   Hepatosplenic T-Cell Lymphoma;   Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma;   Mediastinal (Thymic) Large B-Cell Lymphoma;   Nasal Type Extranodal NK/T-Cell Lymphoma;   Peripheral T-Cell Lymphoma, Not Otherwise Specified;   Primary Cutaneous Anaplastic Large Cell Lymphoma;   Refractory Anaplastic Large Cell Lymphoma;   Small Lymphocytic Lymphoma;   Subcutaneous Panniculitis-Like T-Cell Lymphoma
Interventions: Dietary Supplement: Cholecalciferol;   Other: Laboratory Biomarker Analysis
11 Recruiting Prophylactic Antibiotic Regimens in Tumor Surgery (PARITY)
Conditions: Infection;   Bone Neoplasms
Interventions: Drug: 24-Hour Prophylactic Cefazolin* Antibiotic Regimen;   Drug: 5-Days Prophylactic Cefazolin* Antibiotic Regimen
12 Recruiting A Phase 1-2 Multi-Center Study Evaluating KTE-C19 in Subjects With Refractory Aggressive Non-Hodgkin Lymphoma (ZUMA-1)
Conditions: Refractory Diffuse Large B Cell Lymphoma;   Refractory Primary Mediastinal B Cell Lymphoma;   Refractory Transformed Follicular Lymphoma;   Relapsed/Refractory Transplant Ineligible Diffuse Large B Cell Lymphoma;   Relapsed/Refractory Transplant Ineligible Primary Mediastinal B Cell Lymphoma;   Relapsed/Refractory Transplant Ineligible Transformed Follicular Lymphoma
Intervention: Biological: KTE-C19
13 Recruiting Study to Evaluate the Safety, Tolerability, and Pharmacodynamics of Investigational Treatments in Combination With Standard of Care Immune Checkpoint Inhibitors in Participants With Advanced Melanoma
Condition: Melanoma
Interventions: Drug: TAK-580;   Drug: TAK-202;   Drug: vedolizumab;   Drug: nivolumab;   Drug: ipilimumab
14 Recruiting Study of Blood Samples From Newborns With Down Syndrome
Condition: Leukemia
Interventions: Genetic: DNA analysis;   Genetic: RNA analysis;   Genetic: cytogenetic analysis;   Genetic: fluorescence in situ hybridization;   Genetic: gene expression analysis;   Genetic: microarray analysis;   Genetic: mutation analysis;   Genetic: polymerase chain reaction;   Genetic: polymorphism analysis;   Other: flow cytometry;   Other: laboratory biomarker analysis;   Other: pharmacological study
15 Recruiting Genetic Testing in Screening Patients With Stage IB-IIIA Non-Small Cell Lung Cancer That Has Been or Will Be Removed by Surgery (The ALCHEMIST Screening Trial)
Conditions: Large Cell Lung Carcinoma;   Lung Adenocarcinoma;   Stage IB Non-Small Cell Lung Carcinoma;   Stage IB Squamous Cell Lung Carcinoma;   Stage IIA Non-Small Cell Lung Carcinoma;   Stage IIA Squamous Cell Lung Carcinoma;   Stage IIB Non-Small Cell Lung Carcinoma;   Stage IIB Squamous Cell Lung Carcinoma;   Stage IIIA Non-Small Cell Lung Cancer;   Stage IIIA Squamous Cell Lung Carcinoma
Interventions: Other: Cytology Specimen Collection Procedure;   Other: Laboratory Biomarker Analysis
16 Recruiting A Safety Study of SGN-CD352A for Patients With Relapsed/Refractory Multiple Myeloma
Condition: Multiple Myeloma
Intervention: Drug: SGN-CD352A
17 Recruiting Enzalutamide for Patients With Androgen Receptor Positive Salivary Cancers
Condition: Salivary Cancer
Intervention: Drug: enzalutamide
18 Recruiting Collecting and Storing Tissue Samples From Patients With Rare or Cutaneous Non-Hodgkin Lymphoma
Conditions: Lymphoma;   Lymphoproliferative Disorder
Interventions: Other: biologic sample preservation procedure;   Other: informational intervention
19 Recruiting S1207 Hormone Therapy With or Without Everolimus in Treating Patients With Breast Cancer
Condition: Breast Cancer
Interventions: Drug: anastrozole;   Drug: everolimus;   Drug: exemestane;   Drug: goserelin acetate;   Drug: letrozole;   Drug: leuprolide acetate;   Drug: tamoxifen citrate;   Other: placebo
20 Recruiting Collecting and Storing Samples of Blood and Tumor Tissue From Patients With Osteosarcoma
Condition: Sarcoma
Intervention: Other: biologic sample preservation procedure

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Study has passed its completion date and status has not been verified in more than two years.