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11 studies found for:    Hoffmann-La Roche SMA
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Rank Status Study
1 Recruiting A Study to Evaluate Long Term Safety, Tolerability, and Effectiveness of Olesoxime in Patients With Spinal Muscular Atrophy
Condition: Spinal Muscular Atrophy
Intervention: Drug: Olesoxime
2 Completed Ability of Muscle Imaging and Motor Function Measure (MFM) to Detect Changes in Disease Progression in Ambulant Spinal Muscular Atrophy Patients Compared to Healthy Volunteers.
Condition: Healthy Volunteer, Muscular Atrophy, Spinal
Intervention:
3 Recruiting A Study of RO7034067 in Adult and Pediatric Participants With Spinal Muscular Atrophy
Condition: Spinal Muscular Atrophy
Intervention: Drug: RO7034067
4 Completed A Study to Collect Blood Samples From Patients With Spinal Muscular Atrophy for Biomarker Analysis
Condition: Muscular Atrophy, Spinal
Intervention:
5 Recruiting A Study to Investigate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Efficacy of RO7034067 in Infants With Type1 Spinal Muscular Atrophy (Firefish)
Condition: Muscular Atrophy, Spinal
Intervention: Drug: RO7034067
6 Recruiting A Study to Investigate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Efficacy of RO7034067 in Type 2 and 3 Spinal Muscular Atrophy Participants (Sunfish)
Condition: Muscular Atrophy, Spinal
Interventions: Drug: Placebo;   Drug: RO7034067
7 Terminated A Study of RO6885247 in Adult and Pediatric Patients With Spinal Muscular Atrophy (MOONFISH)
Condition: Muscular Atrophy, Spinal
Interventions: Drug: RO6885247;   Drug: placebo
8 Completed Safety and Efficacy of Olesoxime (TRO19622) in 3-25 Years SMA Patients.
Conditions: Spinal Muscular Atrophy Type II;   Spinal Muscular Atrophy Type III Non Ambulant
Interventions: Drug: Olesoxime;   Drug: Placebo
9 Completed A Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of RO7034067 (RG7916) Given by Mouth in Healthy Volunteers
Condition: Spinal Muscular Atrophy
Interventions: Drug: Itraconazole;   Other: Placebo;   Drug: RO7034067
10 Recruiting Study for Participants With Ulcerative Colitis Previously Enrolled in Etrolizumab Phase II/III Studies
Condition: Ulcerative Colitis
Intervention: Drug: Etrolizumab
11 Recruiting A Study Comparing the Efficacy and Safety of Etrolizumab With Adalimumab and Placebo in Participants With Moderate to Severe Ulcerative Colitis (UC) in Participants Naive to Tumor Necrosis Factor (TNF) Inhibitors (Study #1)
Condition: Ulcerative Colitis
Interventions: Drug: Adalimumab;   Other: Adalimumab Placebo;   Drug: Etrolizumab;   Other: Etrolizumab Placebo

Study has passed its completion date and status has not been verified in more than two years.