30 studies found for:    Heart valve disease OR valve stenosis OR regurgitation | Open Studies | NIH, U.S. Fed
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Rank Status Study
1 Recruiting New Techniques to Evaluate Mitral Regurgitation
Condition: Mitral Valve Regurgitation
Intervention:
2 Recruiting Safety of Ataciguat in Patients With Moderate Calcific Aortic Valve Stenosis
Condition: Aortic Valve Stenosis
Interventions: Drug: Ataciguat;   Drug: Placebo
3 Unknown  POsition of Leads in Advanced heaRt Failure: the POLAR Study
Conditions: Cardiac Resynchronization Therapy;   Heart Failure
Interventions: Procedure: Postero-lateral;   Procedure: Antero-Lateral
4 Recruiting A Study Evaluating the Effects of Ataciguat (HMR1766) on Aortic Valve Calcification
Condition: Aortic Valve Stenosis
Interventions: Drug: Ataciguat (HMR1766);   Other: Placebo Comparator: Matching Placebo
5 Not yet recruiting Evaluating the Benefit of Concurrent Tricuspid Valve Repair During Mitral Surgery
Conditions: Mild Tricuspid Regurgitation;   Moderate Tricuspid Regurgitation;   Tricuspid Regurgitation
Interventions: Procedure: TV Annuloplasty;   Procedure: MVS Alone
6 Recruiting Transcaval Access for Transcatheter Aortic Valve Replacement in People With No Good Options for Aortic Access
Condition: Aortic Valve Stenosis
Intervention: Procedure: CA-TAVR
7 Recruiting Cardiovascular Disease Screening
Conditions: Congenital Heart Disease;   Atherosclerosis;   Myocardial Ischemia;   Myocardial Infarction;   Acquired Heart Disease
Intervention:
8 Unknown  Infective Endocarditis in Developing Countries, a Prospective, Observational, Multicentre Study
Condition: Infective Endocarditis
Intervention:
9 Recruiting Comparison of Nexium Versus Secretol in the Healing and Controlling of Symptoms in GERD Patients With Severe EE.
Conditions: Gastroesophageal Reflux Disease (GERD);   Heartburn;   Indigestion
Interventions: Drug: Secretol;   Drug: Nexium
10 Recruiting Williams Syndrome (WS) and Supravalvular Aortic Stenosis (SVAS) DNA and Tissue Bank
Conditions: Williams Syndrome;   Supravalvular Aortic Stenosis;   Cardiovascular Disease
Intervention:
11 Recruiting Neuroprotection in Patients Undergoing Aortic Valve Replacement
Conditions: Aortic Stenosis;   Brain Infarction;   Cerebrovascular Accident;   Stroke
Interventions: Device: Embol-X Embolic Protection Device;   Device: CardioGard Cannula
12 Recruiting WS-SAVE Study (Williams Syndrome Skin and Vessel Elasticity Study)
Conditions: Williams Syndrome;   Cardiovascular Disease;   Multisystem Developmental Disorder;   Elastin Gene Deletion;   Hypertension
Intervention:
13 Recruiting Exercise in Genetic Cardiovascular Conditions
Conditions: Hypertrophic Cardiomyopathy;   Long QT Syndrome
Intervention:
14 Recruiting Radiation-Free Heart Catheterization Using MRI
Conditions: Aortic Coarctation;   Cardiomyopathy;   Atrial Septal Defect;   Aortic Stenosis;   Post Heart Transplant Catheter Procedure;   Patent Ductus Arteriosus
Interventions: Procedure: MRI guided cardiac catheterization;   Device: Magnetic resonance imaging
15 Recruiting Defining the Brain Phenotype of Children With Williams Syndrome
Condition: Williams Syndrome
Intervention:
16 Recruiting HCMR - Novel Markers of Prognosis in Hypertrophic Cardiomyopathy
Condition: Hypertrophic Cardiomyopathy
Intervention: Other: None - this is an observational study
17 Recruiting Valsartan for Attenuating Disease Evolution In Early Sarcomeric HCM
Condition: Hypertrophic Cardiomyopathy
Interventions: Drug: Valsartan;   Drug: Placebo
18 Recruiting Genotype-Phenotype Associations in Pediatric Cardiomyopathy (PCM GENES)
Conditions: Dilated Cardiomyopathy;   Hypertrophic Cardiomyopathy;   Restrictive Cardiomyopathy
Intervention:
19 Recruiting Hypertrophic Regression With N-Acetylcysteine in HCM
Condition: Hypertrophic Cardiomyopathy
Interventions: Drug: N-acetylcysteine;   Drug: Placebo
20 Recruiting Metabolic Effects of Non-nutritive Sweeteners
Condition: Obesity
Interventions: Dietary Supplement: Sucralose;   Other: Water;   Dietary Supplement: glucose load

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Indicates status has not been verified in more than two years