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70 studies found for:    GIST | Open Studies
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Rank Status Study
1 Recruiting A Randomised Trial of Imatinib Alternating With Regorafenib Compared to Imatinib Alone for the First Line Treatment of Advanced Gastrointestinal Stromal Tumour (GIST)
Condition: Gastrointestinal Stromal Tumour
Interventions: Drug: Regorafenib;   Drug: imatinib
2 Recruiting A Study to Evaluate the Safety of Intuvax Administered Intra-tumorally in Patients With Gastrointestinal Stromal Tumors
Condition: Gastrointestinal Stromal Tumor
Intervention: Biological: Intuvax (suspension for intratumoral injection)
3 Recruiting GIST: Assessment of Tumor Mutations and TKI Plasma Exposure
Condition: Gastro-intestinal Stromal Tumor
Interventions: Procedure: Vena puncture for blood collection;   Procedure: Tumor biopsy
4 Recruiting SSG XXV: The Stop-GIST Trial; Discontinuation of Imatinib in Patients With Oligo-metastatic GIST
Condition: Gastrointestinal Stromal Tumor
Intervention: Other: Discontinuation of imatinib
5 Recruiting Circulating Cell-free Tumor DNA in the Plasma of Patients With Gastrointestinal Stromal Tumors (GIST)
Condition: Gastrointestinal Stromal Tumor (GIST)
Intervention: Other: Vena puncture for blood collection
6 Not yet recruiting Long Outcome of Endoscopic Submucosal Dissection for Small Gastrointestinal Stromal Tumors (<2cm)
Condition: GIST
Intervention: Procedure: ESD
7 Recruiting Surgery for Locally Unresectable Advanced GISTs Without Metastasis After Imatinib Therapy
Condition: Gastrointestinal Stromal Tumor
Intervention:
8 Recruiting MEK162 in Combination With Imatinib Mesylate in Patients With Untreated Advanced Gastrointestinal Stromal Tumor (GIST)
Condition: Gastrointestinal Stromal Tumor (GIST)
Interventions: Drug: MEK162;   Drug: Imatinib Mesylate (Gleevec®; STI571; NSC #716051);   Other: Blood draws;   Procedure: biopsy
9 Recruiting A Study of AUY922 for GIST(Gastrointestinal Stromal Tumor) Patients
Condition: Gastrointestinal Stromal Tumor
Intervention: Drug: AUY922
10 Recruiting Ph II CABOGIST in GIST
Condition: Metastatic Gastrointestinal Stromal Tumor
Intervention: Drug: cabozantinib
11 Recruiting Single Agent Regorafenib in First-line for Metastatic/Unresectable KIT/PDGFR Wild Type GIST
Condition: Gastrointestinal Stromal Tumors
Intervention: Drug: regorafenib
12 Not yet recruiting MITIGATE-NeoBOM: A Study to Evaluate 68Ga- NeoBOMB1 in Patients With Advanced TKI-treated GIST Using PET/CT
Condition: Gastrointestinal Stromal Tumors
Intervention: Drug: 68Ga-NeoBOMB1, 2-vial kit
13 Recruiting A Phase II Trial of the Mitogen Activated Protein Kinase Kinase (MEK1/2) Inhibitor Selumetinib (AZD6244 Hydrogen Sulfate) in Patients With Neurofibromatosis Type 1 (NF1) Mutated Gastrointestinal Stromal Tumors (GIST)
Conditions: Neoplasms, Nerve Tissue;   Neurofibromatosis 1;   Heredodegenerative Disorders, Nervous System;   Peripheral Nervous System Diseases
Intervention: Drug: Selumetinib (AZD6244 hyd sulfate)
14 Recruiting Phase 1 Study of BLU-285 in Patients With Gastrointestinal Stromal Tumors (GIST) and Other Relapsed and Refractory Solid Tumors
Conditions: Gastrointestinal Stromal Tumors (GIST);   Other Relapsed or Refractory Solid Tumors
Intervention: Drug: BLU-285
15 Recruiting Regorafenib in GIST With Secondary C-KIT Exon 17 Mutation
Condition: Gastrointestinal Stromal Tumour (GIST)
Intervention: Drug: regorafenib
16 Recruiting Imatinib Dose Escalation to 800 mg/Day in Korean Patients With Metastatic or Unresectable GIST Harboring KIT Exon 9 Mutation
Condition: Gastrointestinal Stromal Tumors
Intervention: Drug: imatinib
17 Recruiting Randomized Trial of Crenolanib in Subjects With D842V Mutated GIST
Condition: GIST With D842V Mutated PDGFRA Gene
Interventions: Drug: Crenolanib;   Drug: Placebo
18 Not yet recruiting Efficacy of Ferric Carboxymaltose in Patients With Gastrointestinal Stromal Tumor (GIST) Receiving Systemic Therapy
Conditions: Malignant Neoplasms of Mesothelial and Soft Tissue;   Gastrointestinal Stromal Tumor With Neurogenic Differentiation
Interventions: Drug: Ferric Carboxymaltose;   Dietary Supplement: Iron Supplements;   Behavioral: Questionnaire
19 Recruiting A Clinical Trial Evaluating the Efficacy and Safety of Dasatinib in Refractory Metastatic GIST
Condition: Gastrointestinal Stromal Tumor
Intervention: Drug: dasatinib
20 Recruiting A Study of Sunitinib In Young Patients With Advanced Gastrointestinal Stromal Tumor
Condition: Gastrointestinal Stromal Tumors
Interventions: Drug: sunitinib malate dose escalation;   Drug: sunitinib malate

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Study has passed its completion date and status has not been verified in more than two years.