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73 studies found for:    FANCA
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Rank Status Study
1 Recruiting Clinical Phase II Trial to Evaluate CD34+ Cells Mobilization and Collection in Patients With Fanconi Anemia for Subsequent Transduction With a Lentiviral Vector Carring FANCA Gene. FANCOSTEM-1
Condition: Fanconi Anemia
Interventions: Drug: filgrastim;   Drug: plerixafor
2 Completed Oxandrolone for the Treatment of Bone Marrow Aplasia in Fanconi Anemia
Condition: Fanconi Anemia
Intervention: Drug: Oxandrolone
3 Recruiting Hematopoietic Stem Cell Transplantation in High Risk Patients With Fanconi Anemia
Condition: Fanconi Anemia
Interventions: Biological: anti-thymocyte globulin;   Biological: filgrastim;   Drug: busulfan;   Drug: cyclophosphamide;   Drug: fludarabine phosphate;   Drug: methylprednisolone;   Biological: Hematopoietic stem cell transplantation
4 Terminated Gene Function in Bone Marrow Cells From Patients With Fanconi Anemia and From Healthy Participants
Condition: Fanconi Anemia
Interventions: Genetic: microarray analysis;   Procedure: biopsy
5 Recruiting Gene Therapy for Fanconi Anemia
Condition: Fanconi Anemia
Interventions: Biological: Genetically Engineered Hematopoietic Stem Progenitor Cells;   Procedure: Harvest Procedure;   Other: Laboratory Biomarker Analysis
6 Recruiting Cytoxan, Fludara, and Antithymocyte Globulin Conditioning Followed By Stem Cell Transplant in Treating Fanconi Anemia
Condition: Fanconi Anemia
Interventions: Biological: anti-thymocyte globulin;   Drug: cyclophosphamide;   Drug: fludarabine phosphate;   Procedure: hematopoietic stem cell transplantation;   Drug: methylprednisolone;   Drug: filgrastim;   Drug: cyclosporine;   Drug: Mycophenolate Mofetil
7 Recruiting Quercetin in Children With Fanconi Anemia; a Pilot Study
Condition: Fanconi Anemia
Intervention: Drug: Quercetin (dietary supplement)
8 Completed Multicenter Transplant Study for Fanconi Anemia
Condition: Fanconi Anemia
Interventions: Drug: Chemotherapy;   Biological: Miltenyi CliniMACS
9 Recruiting Mobilization and Collection of Peripheral Blood Stem Cells in Patients With Fanconi Anemia Using G-CSF and Plerixafor
Condition: Fanconi Anemia
Interventions: Drug: G-CSF;   Drug: Plerixafor
10 Enrolling by invitation Unrelated HSCT in Patients With Fanconi Anemia
Condition: Fanconi Anemia
Intervention: Biological: CD34+ selected cells
11 Completed Mobilization and Collection of Peripheral Blood Stem Cells in Patients With Fanconi Anemia Using G-CSF and AMD3100
Condition: Fanconi Anemia
Interventions: Drug: AMD3100;   Device: AmCell CliniMACs
12 Completed Cyclophosphamide in Treating Patients Who Are Undergoing a Donor Bone Marrow Transplant for Fanconi's Anemia
Condition: Fanconi Anemia
Interventions: Drug: cyclophosphamide;   Drug: cyclosporine;   Drug: methotrexate;   Procedure: allogeneic bone marrow transplantation;   Procedure: nonmyeloablative allogeneic hematopoietic stem cell transplantation
13 Completed Pilot Study of Etanercept (Enbrel) in Children With Fanconi Anemia
Condition: Fanconi Anemia
Intervention: Drug: Etanercept
14 Active, not recruiting Hematopoietic Stem Cell Transplant for Fanconi Anemia
Condition: Fanconi Anemia
Intervention: Device: CliniMACs device
15 Completed Tissue Sample Collection From Patients With Fanconi Anemia
Conditions: Fanconi Anemia;   Unspecified Adult Solid Tumor, Protocol Specific;   Unspecified Childhood Solid Tumor, Protocol Specific
Interventions: Other: biologic sample preservation procedure;   Procedure: biopsy
16 Terminated Safety and Efficacy Trial of Danazol in Patients With Fanconi Anemia or Dyskeratosis Congenita
Conditions: Fanconi Anemia;   Dyskeratosis Congenita
Intervention: Drug: danazol
17 Completed Identification of de Novo Fanconi Anemia in Younger Patients With Newly Diagnosed Acute Myeloid Leukemia
Conditions: Childhood Acute Erythroleukemia (M6);   Childhood Acute Megakaryocytic Leukemia (M7);   Childhood Acute Minimally Differentiated Myeloid Leukemia (M0);   Childhood Acute Monoblastic Leukemia (M5a);   Childhood Acute Monocytic Leukemia (M5b);   Childhood Acute Myeloblastic Leukemia With Maturation (M2);   Childhood Acute Myeloblastic Leukemia Without Maturation (M1);   Childhood Acute Myelomonocytic Leukemia (M4);   Childhood Myelodysplastic Syndromes;   Chronic Myelomonocytic Leukemia;   de Novo Myelodysplastic Syndromes;   Fanconi Anemia;   Refractory Anemia;   Refractory Anemia With Excess Blasts;   Refractory Anemia With Excess Blasts in Transformation;   Refractory Anemia With Ringed Sideroblasts;   Secondary Myelodysplastic Syndromes;   Untreated Childhood Acute Myeloid Leukemia and Other Myeloid Malignancies
Intervention: Other: laboratory biomarker analysis
18 Completed Gene Therapy for the Treatment of Fanconi's Anemia Type C
Conditions: Fanconi's Anemia;   Pancytopenia
Intervention: Drug: Transduced CD34+ Cells
19 Terminated
Has Results
Stem Cell Transplantation for Fanconi Anemia
Condition: Fanconi Anemia
Interventions: Procedure: Hematopoietic Stem Cell Transplant;   Procedure: Thymic Shielding During Radiation;   Procedure: Total Body Irradiation;   Drug: Cyclophosphamide, Fludarabine
20 Completed Bone Marrow Cell Gene Transfer in Individuals With Fanconi Anemia
Condition: Fanconi Anemia
Intervention: Genetic: Retrovirus Construct

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