| 1 |
NCT02622360 |
Enrolling by invitation |
Speech and Short-term Memory Functions in Dyslexia: a Combined MEG and EEG Study |
|
|
Observational |
|
- Helsinki University
- Helsinki University Central Hospital
- Karolinska Institutet
|
Other |
- Observational Model: Case-Control
- Time Perspective: Retrospective
|
- Magnetic mismatch negativity brain responses to speech sound changes
- Magnetoencephalographic amplitude envelope inter-subject correlation during listening to complex real-life speech
- Event-related brain responses to pseudowords
- (and 2 more...)
|
200 |
All |
18 Years to 45 Years (Adult) |
NCT02622360 |
12345 |
SMeDy |
July 2015 |
December 2019 |
December 2020 |
December 4, 2015 |
March 3, 2017 |
|
- Laboratory of CBRU, Institute of Behavioural Sciences, University of Helsinki
Helsinki, Uusimaa, Finland
|
| 2 |
NCT01012778 |
Completed |
Implementation of Climb Up Program for Children With Attention Deficit Hyperactivity Disorder (ADHD) and Dyslexia in a School in India |
- Attention Deficit Hyperactivity Disorder
- Dyslexia
|
- Behavioral: Climb Up ADHD and Dyslexia Program
|
Interventional |
Phase 1
Phase 2 |
|
Other |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Changes in ADHD scores using Vanderbilt
- Improvement in self-care as assessed by improvement in dental Decayed, Missing and Filled Teeth (DMFT) scores
- Improvement in speed and accuracy of reading samples for children with Dyslexia
|
76 |
All |
6 Years to 11 Years (Child) |
NCT01012778 |
NAJMDKV2007 |
ClimbUp |
May 2007 |
August 2015 |
August 2015 |
November 13, 2009 |
August 4, 2015 |
|
- MDKV Schools
Najibabad, UP, India
|
| 3 |
NCT03285789 |
Not yet recruiting |
Dyslexics' Visual Attention Field |
|
- Other: Passing tests in dyslexics with reduced eva
- Other: Passing tests in controls
|
Interventional |
Not Applicable |
|
Other |
- Allocation: Non-Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Other
|
- Respond time in visual search in different condition of view (full view or reduced view) with separable feature.
- respond time in function of the distractors' number
- visual exploration of the scene
- (and 2 more...)
|
63 |
All |
8 Years to 12 Years (Child) |
NCT03285789 |
69HCL17_0333 |
|
March 1, 2018 |
March 2, 2020 |
March 2, 2020 |
September 18, 2017 |
February 23, 2018 |
|
- U1028 INSERM - CNRS UMR 5292 Equipe ImpAct
Bron, France
|
| 4 |
NCT02879786 |
Completed |
Study of Hierarchy of Afferents in Postural Control of Children With Dyslexia |
|
- Other: Posturographic tests
- Other: Questionnaire of motion sickness susceptibility
|
Interventional |
Not Applicable |
- Central Hospital, Nancy, France
|
Other |
- Allocation: Non-Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Diagnostic
|
- Score of evaluation of motion sickness susceptibility
- Score of equilibrium evaluated with posturographic test
|
68 |
All |
8 Years to 13 Years (Child) |
NCT02879786 |
2011-A00139-32 |
EQUIDYS |
July 2011 |
June 2015 |
June 2015 |
August 26, 2016 |
August 26, 2016 |
|
- Centre de Référence pour les Troubles des Apprentissages - Hôpital d'Enfants - CHU de Nancy
Vandoeuvre lès Nancy, France
|
| 5 |
NCT03364010 |
Recruiting |
Dyslexia, Motor Control and Proprioception |
|
- Behavioral: Evaluation of proprioception
- Behavioral: Evaluation of motor learning
- Behavioral: Evaluation of written language
|
Interventional |
Not Applicable |
- Institut National de la Santé Et de la Recherche Médicale, France
|
Other |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Basic Science
|
- Evaluation of proprioception through velocity perception
- Evaluation of proprioception through position perception
- Motor learning
- (and 3 more...)
|
163 |
All |
10 Years to 12 Years (Child) |
NCT03364010 |
C17-14
2017-A01547-46 |
|
January 4, 2018 |
March 15, 2019 |
October 15, 2019 |
December 6, 2017 |
January 8, 2018 |
|
- Inserm U1093
Dijon, Bourgogne, France
|
| 6 |
NCT02345876 |
Active, not recruiting |
Maturation of Auditory Processing in Children With Dyslexia Compared to Average-reading Children |
|
|
Observational |
|
|
Other |
- Observational Model: Case-Control
- Time Perspective: Prospective
|
- Change of The Asymmetry Index of the efferent system at 2 years interval
- Change in the level of reading skill
- Change in the percentage of correct answers obtained during a speech perception test in silence and noise.
- Change in percentage of correctly repeated stimuli which have been heard in both ears (binaural integration with divided attention) or in one indicated ear (binaural separation with selective attention)
|
161 |
All |
6 Years to 11 Years (Child) |
NCT02345876 |
2013-799 |
ASTRAUCOLE |
March 11, 2014 |
June 7, 2019 |
June 7, 2019 |
January 26, 2015 |
March 8, 2018 |
|
- Centre Hospitzlier Le Vinatier
Bron, France - Service ORL CHU Montpied
Clermont-Ferrand, France - Service d'Audiologie et Explorations Orofaciales Centre de Référence des Troubles des Apprentissages
Lyon, France
|
| 7 |
NCT02107534 |
Unknown † |
Group-based Training for Parents of Children With Dyslexia |
- Dyslexia
- Reading Disorder
- Reading Disability
- Developmental Reading Disorder
|
- Behavioral: parent training (dyslexia)
|
Interventional |
Not Applicable |
- University of Heidelberg Medical Center
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Treatment
|
- Change from Baseline in Parenting Stress Index at 12 weeks
- Change in Baseline in Parenting Stress Index at 36 weeks
|
42 |
All |
Child, Adult, Senior |
NCT02107534 |
S-480/2012 |
|
January 2012 |
September 2014 |
October 2014 |
April 8, 2014 |
April 8, 2014 |
|
- University of Heidelberg Medical Center
Heidelberg, Baden-Württemberg, Germany
|
| 8 |
NCT02429739 |
Completed |
Working Memory Training for Children With Dyslexia |
|
- Behavioral: Working memory Training
|
Interventional |
Not Applicable |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Treatment
|
- Reading fluency, comprehension and speed
- Working Memory Capacity
|
32 |
All |
9 Years to 16 Years (Child) |
NCT02429739 |
Sorlandet Hospital 2014/1057 |
|
October 2014 |
April 2016 |
April 2016 |
April 29, 2015 |
April 26, 2016 |
|
- Sorlandet Hospital
Arendal, Aust-Agder, Norway
|
| 9 |
NCT00068835 |
Unknown † |
Using fMRI to Evaluate Instructional Programs for Children With Developmental Dyslexia |
|
- Behavioral: Lindamood-Bell training for dyslexia
|
Interventional |
Not Applicable |
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
|
NIH |
- Allocation: Randomized
- Intervention Model: Factorial Assignment
- Masking: Single
- Primary Purpose: Educational/Counseling/Training
|
|
160 |
All |
8 Years to 12 Years (Child) |
NCT00068835 |
5R01HD037890 |
|
June 2000 |
|
May 2005 |
September 11, 2003 |
June 24, 2005 |
|
- Georgetown University
Washington, District of Columbia, United States
|
| 10 |
NCT00111371 |
Unknown † |
Dopaminergic Enhancement of Learning and Memory in Healthy Adults and Patients With Dyslexia |
|
|
Interventional |
Phase 4 |
- University Hospital Muenster
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double
- Primary Purpose: Treatment
|
- Boost in training success (percent correct) through levodopa as compared to placebo
- Boost in training success (reaction times) through levodopa as compared to placebo
- Increased performance on reading, spelling and writing tests in dyslexic patients treated with levodopa as compared to placebo
- Stability of improvements one month post training
|
100 |
Male |
18 Years to 35 Years (Adult) |
NCT00111371 |
LL-001; Project on Dyslexia |
|
January 2005 |
|
October 2015 |
May 20, 2005 |
December 5, 2014 |
|
- Dept. of Neurology, University Hospital of Muenster
Muenster, North-Rhine Westphalia, Germany
|
| 11 |
NCT01860027 |
Terminated |
Eye Movements and Reading Disabilities |
- Reading Disability
- Dyslexia
|
|
Observational |
|
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Sensitivity and specificity of clinical eye movement devices
- Comparison of eye movement characteristics amongst patients with reading disorders, eye movement abnormalities and control subjects.
|
1 |
All |
7 Years to 13 Years (Child) |
NCT01860027 |
EOMRD |
EOMRD |
December 2013 |
September 2014 |
September 2014 |
May 22, 2013 |
May 20, 2015 |
|
- Scripps Clinic
San Diego, California, United States
|
| 12 |
NCT00254644 |
Completed |
Morphofunctional Imaging and Developmental Dyslexia |
|
- Procedure: Morphological and functional MRI
|
Observational |
|
- University Hospital, Tours
|
Other |
- Observational Model: Case Control
- Time Perspective: Prospective
|
- Cortical thickness
- Average cortical thickness
|
32 |
Male |
18 Years to 35 Years (Adult) |
NCT00254644 |
PHRR04-CH/DYS |
PHR04-CH/DYS |
February 2007 |
February 2008 |
February 2008 |
November 16, 2005 |
January 16, 2017 |
|
|
| 13 |
NCT03119402 |
Recruiting |
Effects of the Combination of RRT With tDCS on Dyslexic Adults |
|
- Behavioral: Rhythmic Reading Training
- Device: Transcranial direct current stimulation
|
Interventional |
Not Applicable |
- Catholic University of the Sacred Heart
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Participant)
- Primary Purpose: Treatment
|
- Text reading speed expressed in syllables per seconds
- Text reading accuracy expressed in number of errors
- Word reading speed expressed in syllables per seconds
- (and 6 more...)
|
20 |
All |
19 Years to 30 Years (Adult) |
NCT03119402 |
RRT+tDCS |
|
April 18, 2017 |
September 4, 2017 |
April 4, 2018 |
April 18, 2017 |
January 25, 2018 |
|
- Catholic University of the Sacred Heart
Milan, Italy
|
| 14 |
NCT02791841 |
Recruiting |
Comparison of Interventions for Developmental Dyslexia |
|
- Behavioral: Rhythmic Reading Training
- Behavioral: Visual Hemispheric-Specific Stimulation + Action Video Games
- Behavioral: Action Video Games
|
Interventional |
Not Applicable |
- Catholic University of the Sacred Heart
- IRCCS Eugenio Medea
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Text reading
- Word reading
- Pseudo-word reading
- (and 5 more...)
|
33 |
All |
8 Years to 12 Years (Child) |
NCT02791841 |
RRT-VHSS-AVG |
|
January 2016 |
June 2017 |
April 2018 |
June 7, 2016 |
January 25, 2018 |
|
- Unit of Child Psychopathology, Scientific Institute IRCCS 'Eugenio Medea'
Bosisio Parini, Italy
|
| 15 |
NCT01930500 |
Completed |
The Effectiveness of Neuropsychological Rehabilitation in Young Dyslexic Adults |
|
- Behavioral: Individual neuropsychological rehabilitation
- Behavioral: Group based neuropsychological rehabilitation
|
Interventional |
Not Applicable |
- Rehabilitation Foundation, Finland
- Helsinki University Central Hospital
- Social Insurance Institution, Finland
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Treatment
|
- Subjective cognitive performance
- Subjective reading related performance
- Objective cognitive performance
- (and 4 more...)
|
120 |
All |
18 Years to 35 Years (Adult) |
NCT01930500 |
Luki-40211 |
|
November 2012 |
November 2015 |
December 2017 |
August 29, 2013 |
April 11, 2018 |
|
- Rehabilitation Foundation
Helsinki, Malminkartano, Finland
|
| 16 |
NCT00716274 |
Completed
Has Results |
Effects of Atomoxetine on Brain Activation During Attention & Reading Tasks in Participants With ADHD & Comorbid Dyslexia |
- Attention Deficit Hyperactivity Disorder
- Dyslexia
|
- Drug: Atomoxetine
- Drug: Placebo
|
Interventional |
Phase 4 |
|
Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Participant, Investigator)
- Primary Purpose: Treatment
|
- Change From Baseline to Endpoint in Functional Magnetic Resonance Imaging (fMRI) Activation in Participants With Dyslexia Alone (Pseudoword Rhyming and Semantic-category Tasks)
- Change From Baseline to Endpoint in fMRI Activation in Participants With Dyslexia Alone (Stroop Attention Tasks)
- Change From Baseline to Endpoint in fMRI Activation in Participants With Attention Deficit Hyperactivity Disorder (ADHD) or ADHD + Dyslexia (Stroop Attention Tasks)
- (and 55 more...)
|
110 |
All |
10 Years to 16 Years (Child) |
NCT00716274 |
12212
B4Z-US-LYEI |
|
September 2008 |
July 2016 |
July 2016 |
July 16, 2008 |
February 7, 2018 |
February 7, 2018 |
- Yale University School of Medicine
New Haven, Connecticut, United States
|
| 17 |
NCT02393729 |
Completed |
Functional MRI Study in Children With a Developmental Coordination Disorder (DCD) and/or Developmental Dyslexia (DD) |
- Developmental Dyslexia
- Developmental Coordination Disorder
|
- Behavioral: Neuropsychological assessment
- Other: MRI Study
|
Interventional |
Not Applicable |
- University Hospital, Toulouse
|
Other |
- Allocation: Non-Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Other
|
- difference in the level of brain activity
- The level of brain activity obtained by fMRI
- The performance of subjects
|
65 |
All |
8 Years to 12 Years (Child) |
NCT02393729 |
10 155 02
N°RCB : 2010-A00909-30 |
FMRI-DCD-DD |
January 2011 |
September 2013 |
September 2013 |
March 19, 2015 |
May 12, 2017 |
|
- Hôpital des Enfants
Toulouse, France
|
| 18 |
NCT02217696 |
Recruiting |
Prediction and Intervention in Developmental Dyslexia |
|
- Other: Computerized reading training
|
Interventional |
Not Applicable |
|
Other |
- Allocation: Randomized
- Intervention Model: Crossover Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Basic Science
|
- Changes in reading and spelling performance
- Developmental and training induced changes in functional brain activation and brain structure
- Accuracy of prediction on reading performance outcome
|
110 |
All |
5 Years to 9 Years (Child) |
NCT02217696 |
LEXI SNF32003B_141201/1
32003B_141201/1 |
LEXI |
July 2013 |
July 2018 |
July 2018 |
August 15, 2014 |
August 15, 2014 |
|
- University Clinics for Child and Adolescent Psychiatry, University of Zurich
Zurich, Switzerland
|
| 19 |
NCT00607919 |
Completed
Has Results |
Treatment of ADHD With Atomoxetine in Children & Adolescents With ADHD & Comorbid Dyslexia |
- Attention Deficit Hyperactivity Disorder
- Dyslexia
|
- Drug: Atomoxetine
- Drug: Placebo
|
Interventional |
Phase 4 |
|
Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Participant, Investigator)
- Primary Purpose: Treatment
|
- Change From Baseline in Attention-Deficit/Hyperactivity Disorder Rating Scale (ADHDRS) Total Score - Parent Version at Week 16 Endpoint
- Change From Baseline in Attention-Deficit/Hyperactivity Disorder Rating Scale (ADHDRS) Total and Subscores - Parent Version at Week 16 Endpoint
- Change From Baseline in Attention-Deficit/Hyperactivity Disorder Rating Scale (ADHDRS) Total and Subscores - Teacher Version at Week 16 Endpoint
- (and 18 more...)
|
209 |
All |
10 Years to 16 Years (Child) |
NCT00607919 |
11672
B4Z-US-LYEB |
|
March 2008 |
November 2010 |
February 2011 |
February 6, 2008 |
December 15, 2011 |
December 15, 2011 |
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
Irvine, California, United States - For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
Palo Alto, California, United States - For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
San Francisco, California, United States - (and 13 more...)
|
| 20 |
NCT00245804 |
Completed |
Developmental Dyslexia and Functional Maturation of Auditory Cortex |
- Developmental Reading Disorder
- Dyslexia
|
|
Observational |
|
- University Hospital, Tours
|
Other |
- Observational Model: Case Control
- Time Perspective: Prospective
|
|
60 |
All |
8 Years to 25 Years (Child, Adult) |
NCT00245804 |
PHRR02/CH/DYS-AUT |
DYS-AUT |
March 2003 |
|
February 2005 |
October 28, 2005 |
June 30, 2010 |
|
- University Hospital of Tours
Tours, France
|
| 21 |
NCT03448237 |
Enrolling by invitation |
Orthophonic and / or Proprioceptive Treatment of Developmental Dyslexia. |
|
- Other: Speech Therapy
- Other: Proprioceptive treatment
|
Interventional |
Not Applicable |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Change from baseline C index ( Alouatte-R test) at 9 months
- Change from baseline TL index ( Alouatte-R test) at 9 months
- Change from baseline M index ( Alouatte-R test) at 9 months
- (and 11 more...)
|
39 |
All |
9 Years to 14 Years (Child) |
NCT03448237 |
Scalab 2015-024EL
ID RCB : 2015-A01792-47 |
Pro-Pho-Dys |
February 17, 2018 |
May 2019 |
September 2019 |
February 28, 2018 |
February 28, 2018 |
|
- Scalab CNRS 9193
Villeneuve-d'Ascq, Haut De France, France
|
| 22 |
NCT02316873 |
Completed |
Rhythm and Music to Rehabilitate Reading Disorders |
|
- Behavioral: Music training
- Behavioral: Visual arts
|
Interventional |
Not Applicable |
- Aix Marseille Université
- WHO Collaborating Centre for Maternal and Child Health, Trieste
- University of Roma La Sapienza
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Pseudoword reading test
- Reading text
- Phonological awareness
- Word reading
|
48 |
All |
8 Years to 11 Years (Child) |
NCT02316873 |
ReMus R-11-85 |
ReMus |
September 2011 |
June 2013 |
December 2013 |
December 15, 2014 |
December 15, 2014 |
|
|
| 23 |
NCT00191048 |
Completed |
Treatment With Atomoxetine Hydrochloride in Children and Adolescents With ADHD |
- Attention-Deficit/Hyperactivity Disorder
- Comorbid Dyslexia
|
|
Interventional |
Phase 4 |
|
Industry |
- Allocation: Non-Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- To assess the effect of atomoxetine,given for approximately 16 weeks, in the treatment of ADHD with Dyslexia as measured by the ADHDRS-IV-Parent:Inv
- To assess the effect of atomoxetine on educational testing, working memory,and adaptive functioning throughout 16 weeks.
|
105 |
All |
10 Years to 16 Years (Child) |
NCT00191048 |
7975
B4Z-US-LYCE |
|
October 2003 |
|
March 2006 |
September 19, 2005 |
January 26, 2007 |
|
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician
Rolling Hills Estate, California, United States - For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician
Maitland, Florida, United States - For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician
Miami, Florida, United States - (and 5 more...)
|
| 24 |
NCT03199092 |
Active, not recruiting |
Rhythmic Reading Training Compared to 'Abilmente' Method |
|
- Behavioral: RRT+sat
- Behavioral: Abilmente
|
Interventional |
Not Applicable |
- Catholic University of the Sacred Heart
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Text reading accuracy expressed in number of errors change
- Text reading speed expressed in syllables per seconds change
- Word reading speed expressed in syllables per seconds change
- (and 3 more...)
|
32 |
All |
9 Years to 13 Years (Child) |
NCT03199092 |
RRT-Abilmente |
|
June 26, 2017 |
October 12, 2017 |
April 2018 |
June 26, 2017 |
January 25, 2018 |
|
- Catholic University of the Sacred Heart
Milan, Italy - Studio Abilmente
Milan, Italy
|
| 25 |
NCT00624234 |
Completed
Has Results |
Neurobiology and Treatment of Reading Disability in NF-1 |
- Neurofibromatosis Type 1
- Reading Disabilities
|
- Behavioral: Tutoring Program I
- Behavioral: Tutoring Program II
|
Interventional |
Not Applicable |
- Vanderbilt University
- National Institute of Neurological Disorders and Stroke (NINDS)
|
Other / NIH |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Participant)
- Primary Purpose: Treatment
|
- Change From Baseline in WJ-III Basic Reading Normative Update (Woodcock Johnson Psychoeducational Battery - 3rd Edition; WJ-III NU) Standard Score at 15 Hours
- Neuroimaging Data
|
184 |
All |
8 Years to 17 Years (Child) |
NCT00624234 |
R01NS049096
NF1-R01 |
|
February 2006 |
March 2013 |
January 2017 |
February 27, 2008 |
April 13, 2017 |
April 10, 2017 |
- Vanderbilt University, Vanderbilt University Institute of Imaging Science
Nashville, Tennessee, United States
|
| 26 |
NCT02964884 |
Recruiting |
Interventions for Reading Disabilities in NF1 |
- Neurofibromatosis Type 1
- Learning Disability
- Reading Disability
- NF1
|
- Drug: Lovastatin
- Behavioral: reading tutoring intervention
- Drug: Placebo Oral Tablet
- Behavioral: Other Academic "sham" tutoring
|
Interventional |
Phase 2 |
- Vanderbilt University
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
|
Other / NIH |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Triple (Participant, Care Provider, Investigator)
- Primary Purpose: Treatment
|
- Woodcock Johnson Tests of Achievement IV
- Woodcock Reading Mastery Test-III
- Test of Word Reading Efficiency-2
- (and 7 more...)
|
120 |
All |
8 Years to 20 Years (Child, Adult) |
NCT02964884 |
161159
1R01HD089474-01 |
|
November 2016 |
November 2020 |
June 2022 |
November 16, 2016 |
February 6, 2018 |
|
- Vanderbilt University
Nashville, Tennessee, United States
|
| 27 |
NCT00061412 |
Completed |
Comprehensive Program to Improve Reading and Writing Skills in At-Risk and Dyslexic Children |
- Dyslexia
- Learning Disorders
|
- Behavioral: Comprehensive program to improve reading and writing skills
|
Interventional |
Not Applicable |
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
|
NIH |
- Allocation: Randomized
- Intervention Model: Factorial Assignment
- Masking: Single
- Primary Purpose: Treatment
|
|
2500 |
All |
6 Years and older (Child, Adult, Senior) |
NCT00061412 |
2P50HD33812-6 |
|
December 1995 |
|
November 2005 |
May 28, 2003 |
September 28, 2006 |
|
- University of Washington
Seattle, Washington, United States
|
| 28 |
NCT00191906 |
Completed
Has Results |
Comparison of Atomoxetine and Placebo in Children With Attention-Deficit/Hyperactivity Disorder (ADHD) and/or Reading Disorder (RD) |
- Attention Deficit Hyperactivity Disorder
- Reading Disorder
|
- Drug: Atomoxetine Hydrochloride
- Drug: placebo
|
Interventional |
Phase 4 |
|
Industry |
- Allocation: Randomized
- Intervention Model: Crossover Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Stop Signal Reaction Time (SSRT) as Derived From the Stop Signal Reaction Time Paradigm
- Change From Baseline in Mean Stop Signal Reaction Time Comparison of ADHD-C to Normal Control Group in >=10 Year Old Subset
- Change From Baseline in Mean Stop Signal Reaction Time Comparison of ADHD-C+RD and RD to Reading Disordered Control Group in >=10 Year Old Subset
- (and 13 more...)
|
121 |
All |
8 Years to 12 Years (Child) |
NCT00191906 |
7955
B4Z-MC-LYCK |
|
April 2005 |
December 2007 |
December 2007 |
September 19, 2005 |
May 25, 2010 |
April 6, 2010 |
- For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
Gent, Belgium - For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
Almere, Netherlands - For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
Amsterdam, Netherlands - (and 2 more...)
|
| 29 |
NCT01133847 |
Completed
Has Results |
Interventions for Children With Attention and Reading Disorders |
- Attention Deficit Hyperactivity Disorder
- Reading Disabilities
|
- Drug: Methylphenidate
- Behavioral: Intensive reading instruction
- Behavioral: Parent Training
- (and 3 more...)
|
Interventional |
Phase 4 |
- The University of Texas Health Science Center, Houston
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
- Children's Hospital Medical Center, Cincinnati
|
Other / NIH |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Treatment
|
- Swanson, Nolan, and Pelham Checklist for DSM-IV (SNAP)- Parent Rating of Inattention
- Swanson, Nolan, and Pelham Checklist for DSM-IV (SNAP)- Parent Rating of Hyperactivity-impulsivity
- Swanson, Nolan, and Pelham Checklist for DSM-IV (SNAP)- Teacher Rating of Inattention
- (and 8 more...)
|
222 |
All |
7 Years to 12 Years (Child) |
NCT01133847 |
HSC-MS-09-0531
R01HD060617 |
ICARD |
November 2010 |
June 2015 |
June 2015 |
May 31, 2010 |
April 11, 2017 |
April 11, 2017 |
- Cincinnati Children's Hospital Medical Center
Cincinnati, Ohio, United States - University of Texas Health Science Center
Houston, Texas, United States
|
| 30 |
NCT00065832 |
Completed |
Reading Problems in Children Living in Urban Areas |
|
- Behavioral: Reading Instruction
|
Interventional |
Phase 3 |
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
|
NIH |
- Allocation: Non-Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Prevention
|
|
1400 |
All |
5 Years to 8 Years (Child) |
NCT00065832 |
5R01HD30995-9 |
|
July 1993 |
|
June 2002 |
August 4, 2003 |
June 3, 2015 |
|
|
| 31 |
NCT02397967 |
Completed |
Reading Disability in Children With NF1 |
|
- Other: Neuropsychological assessments
|
Interventional |
Not Applicable |
- University Hospital, Toulouse
|
Other |
- Allocation: Non-Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Screening
|
- Phonological deficits evaluated by the metaphonological capabilities including a subtraction test and phonemic Acronym test and memory capacity with phonological phonological memory test.
- Visual-perceptual performance established from three tests: Test of Identical Forms (Thurstone), Judgment Test of orientation Lines (Benton) and global and partial deferral Tasks (S Valdois).
|
181 |
All |
8 Years to 12 Years (Child) |
NCT02397967 |
08 113 01 |
|
June 2009 |
April 2014 |
April 2014 |
March 25, 2015 |
March 26, 2015 |
|
- Hopital femme-mére-enfant, Hospices civils de lyon
Lyon, France - Hôpital Gui de Chauliac
Montpellier, France - CHU Hôtel-Dieu, Clinic of Dermatology
Nantes, France - (and 3 more...)
|
| 32 |
NCT02872870 |
Completed |
Developmental Language Difficulties: Behavioural and Electrophysiological Studies |
|
- Behavioral: auditory lexical decision task
- Device: electroencephalogram
|
Observational |
|
- Lille Catholic University
- Université de Lille 3
- Université Catholique de Louvain
|
Other |
- Observational Model: Case Control
- Time Perspective: Prospective
|
- Score Alouette reading test
- Score EVALEC reading test
- Score silence reading test
- (and 4 more...)
|
196 |
All |
8 Years and older (Child, Adult, Senior) |
NCT02872870 |
RC-P0020 |
LANGAGE |
March 2012 |
March 2015 |
June 2016 |
August 19, 2016 |
August 19, 2016 |
|
- Université catholique de Louvain (IPSY)
Louvain-la-Neuve, Belgium - Hôpital Saint Vincent de Paul (GHICL)
Lille, France - Université de Lille 3 Charles de Gaulle (URECA)
Villeneuve d'Ascq, France
|
| 33 |
NCT03261661 |
Recruiting |
Improving Response to Intervention in Students With or at Risk of Reading Disabilities |
|
- Behavioral: Reading
- Behavioral: Mindset
- Behavioral: Reading Embedded with Mindset
- Behavioral: Business as Usual
|
Interventional |
Not Applicable |
- Vanderbilt University
- Southern Methodist University
- Florida State University
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Change in Cloze Reading Comprehension
- Change in Passage Reading Comprehension
- Change in Word Reading
- (and 8 more...)
|
864 |
All |
9 Years to 11 Years (Child) |
NCT03261661 |
170686 |
|
August 18, 2017 |
May 31, 2021 |
May 31, 2021 |
August 25, 2017 |
September 11, 2017 |
|
- Vanderbilt University
Nashville, Tennessee, United States - Southern Methodist University
Dallas, Texas, United States
|
| 34 |
NCT00064805 |
Completed |
Therapy for Reading Problems in Adults After Brain Injury |
- Dyslexia, Acquired
- Brain Injuries
- Cerebrovascular Accident
|
- Behavioral: Cognitive Therapy to Improve Reading
|
Interventional |
Not Applicable |
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
|
NIH |
- Allocation: Non-Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Improved accuracy and/or speed of reading individual words aloud.
- Improved accuracy and/or speed of reading text aloud.
|
58 |
All |
18 Years and older (Adult, Senior) |
NCT00064805 |
R01HD036019 |
|
August 2002 |
July 2007 |
July 2007 |
July 15, 2003 |
August 15, 2014 |
|
- Georgetown University Medical Center
Washington, District of Columbia, United States
|
| 35 |
NCT02422732 |
Completed |
Functional Imaging and Reading Deficit in Children With NF1 |
|
- Other: Neuropsychological assessments
- Radiation: morphological and functional MRI (fMRI)
- Genetic: genetic analysis
|
Interventional |
Not Applicable |
- University Hospital, Toulouse
|
Other |
- Allocation: Non-Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Diagnostic
|
- Percentage of children performing in full the protocol functional MRI
- blood flow in milliliters per minute
|
25 |
All |
8 Years to 12 Years (Child) |
NCT02422732 |
08 154 02
2008-A01493-52 |
|
March 2009 |
April 2015 |
April 2015 |
April 21, 2015 |
August 19, 2015 |
|
- CHU Toulouse
Toulouse, France
|
| 36 |
NCT00818428 |
Unknown † |
Randomized Clinical Trial of Phonological Interventions |
- Speech Articulation Disorder
- Developmental Articulation Disorder
- Phonological Impairment
- Dyslexia
|
- Behavioral: Speech Production Intervention
- Behavioral: Speech Perception Intervention
- Behavioral: Articulation Parent Group
- Behavioral: Dialogic Reading Parent Group
|
Interventional |
Phase 2
Phase 3 |
|
Other |
- Allocation: Randomized
- Intervention Model: Factorial Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Prevention
|
- Phonological Awareness (Test d'Analyse Auditive en Français [Auditory Analysis Test in French])
- Articulation Accuracy (Test Francophone de Phonologie, Paul et Rvachew [Test of French Phonology)
- Vocabulary Knowledge (Échelle de Vocabulaire en Image Peabody [Peabody Picture Vocabulary Test - French Edition)
- Phonological Awareness (Test de Conscience Phonologique, Brosseau-Lapre et Rvachew [Phonological Awareness Test - French Version])
|
96 |
All |
48 Months to 71 Months (Child) |
NCT00818428 |
410-2008-0503 |
ECRIP |
November 2008 |
July 2010 |
July 2010 |
January 7, 2009 |
September 23, 2009 |
|
- McGill University
Montreal, Quebec, Canada - Montreal Children's Hospital
Montreal, Quebec, Canada
|
| 37 |
NCT00827268 |
Completed |
Multimodal Treatment of Phonological Alexia: Behavioral & fMRI Outcomes |
- Aphasia
- Stroke
- Dyslexia, Acquired
|
- Behavioral: One-on-one treatment of reading difficulties
|
Interventional |
Not Applicable |
- VA Office of Research and Development
|
U.S. Fed |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Change in Real World Reading Skills
|
5 |
All |
18 Years and older (Adult, Senior) |
NCT00827268 |
B6699-W |
|
June 2009 |
December 2011 |
July 2012 |
January 22, 2009 |
November 30, 2017 |
|
- North Florida/South Georgia Veterans Health System
Gainesville, Florida, United States
|
| 38 |
NCT01388881 |
Unknown † |
Effects of Music Education for Children With Reading Difficulties |
- Difficult; Spelling, With Reading Disorder
|
|
Interventional |
Not Applicable |
- Federal University of São Paulo
- Conselho Nacional de Desenvolvimento Científico e Tecnológico
- Instituto ABCD
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Treatment
|
- Changes in Reading abilities
- Changes in Portuguese achievement
|
270 |
All |
8 Years to 10 Years (Child) |
NCT01388881 |
CEP 0433/10 |
|
March 2011 |
June 2011 |
December 2011 |
July 7, 2011 |
July 25, 2011 |
|
- Federal University of São Paulo - Psychiatry Department
São Paulo, Brazil
|
| 39 |
NCT02680223 |
Recruiting |
Efficacy of Coloured Overlays and Lenses for Reading Difficulty |
- Vision Disorders
- Reading Disabilities
|
- Device: Precision tinted lenses
- Device: Non-beneficial tinted lenses
|
Interventional |
Not Applicable |
- City, University of London
|
Other |
- Allocation: Randomized
- Intervention Model: Crossover Assignment
- Masking: Double (Participant, Investigator)
- Primary Purpose: Treatment
|
|
36 |
All |
18 Years to 30 Years (Adult) |
NCT02680223 |
BA_2015 |
|
January 2016 |
April 2018 |
September 2018 |
February 11, 2016 |
August 31, 2017 |
|
- City University London
London, United Kingdom
|
| 40 |
NCT01046760 |
Unknown † |
Scholar Performance and Praxis Assessment in Children With Rolandic Epilepsy |
|
- Behavioral: Language Assessment
|
Observational |
|
- University of Campinas, Brazil
- Fundação de Amparo à Pesquisa do Estado de São Paulo
|
Other |
- Observational Model: Cohort
- Time Perspective: Retrospective
|
- Our data will indicate the group performance in tests of writing, arithmetic and reading.
- Another important aspect was the absence of orofacial apraxia in children with epilepsy.
|
20 |
All |
7 Years to 12 Years (Child) |
NCT01046760 |
21 CFR 50.3. |
|
September 2009 |
February 2011 |
February 2011 |
January 12, 2010 |
October 20, 2010 |
|
- Clinical Hospital
Campinas, São Paulo, Brazil
|
| 41 |
NCT03261076 |
Not yet recruiting |
Reading Remediation and Outcomes in Detention |
- Specific Learning Disorder (MeSH Unique ID: D000067559)
- Dyslexia (MeSH Unique ID: D004410)
- Conduct Disorder (MeSH Unique ID: D019955)
|
- Behavioral: Strategies Enhancing Reading in Older Underperf. Students
|
Interventional |
Not Applicable |
- Baylor College of Medicine
- University of Houston
- Harris County Juvenile Probation Department (HCJPD)
- (and 2 more...)
|
Other |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Change in Reading Skills from pre-intervention (baseline) to the week after intervention
- Change in Decoding Skills from pre-intervention (baseline) to the week after intervention
- Change in Reading Understanding from pre-intervention (baseline) to the week after intervention
- (and 9 more...)
|
192 |
Male |
14 Years to 16 Years (Child) |
NCT03261076 |
H-40232 |
SERIOUS |
February 9, 2018 |
December 31, 2020 |
December 31, 2020 |
August 24, 2017 |
February 12, 2018 |
|
|
| 42 |
NCT00956579 |
Unknown † |
Sensory and Connectivity Abnormalities in Autism and Language Disorders |
- Autism Spectrum Disorder
- Developmental Language Disorders
|
|
Observational |
|
- Massachusetts General Hospital
- Autism Speaks
- Nancy Lurie Marks Family Foundation
|
Other |
- Observational Model: Case Control
- Time Perspective: Prospective
|
|
260 |
All |
6 Years to 45 Years (Child, Adult) |
NCT00956579 |
2005P001768 |
|
September 2005 |
September 2010 |
September 2010 |
August 11, 2009 |
May 4, 2010 |
|
- Martinos Center or Biomedical Imaging
Charlestown, Massachusetts, United States
|
| 43 |
NCT02062619 |
Completed |
Brain Mechanisms Underlying Reading Improvement in Central Alexia |
- Stroke
- Brain Injuries
- Aphasia
|
- Behavioral: Computer-based behavioural word reading therapy
- Other: Real tDCS
- Other: Sham tDCS
|
Interventional |
Not Applicable |
- University College, London
|
Other |
- Allocation: Randomized
- Intervention Model: Crossover Assignment
- Masking: Double (Participant, Investigator)
- Primary Purpose: Treatment
|
- Change in word reading speed and accuracy for trained and untrained words
- Change in spoken word repetition for trained / untrained words
- Change in semantic word matching for trained / untrained words
|
23 |
All |
18 Years and older (Adult, Senior) |
NCT02062619 |
MR/K022563/1 |
|
March 2014 |
July 2016 |
September 2016 |
February 13, 2014 |
November 4, 2016 |
|
- Institute of Neurology, University College London
London, United Kingdom
|
| 44 |
NCT00001246 |
Recruiting |
Brain Imaging of Childhood Onset Psychiatric Disorders, Endocrine Disorders and Healthy Volunteers |
- XXY (Klinefelter)
- Sex Chromosome Variation
- Sex Chromosome Aneuploidy
- (and 8 more...)
|
|
Observational |
|
- National Institute of Mental Health (NIMH)
- National Institutes of Health Clinical Center (CC)
|
NIH |
- Observational Model: Cohort
- Time Perspective: Cross-Sectional
|
- Volumetric MRI Data
- Cognitive Data
|
6000 |
All |
3 Years and older (Child, Adult, Senior) |
NCT00001246 |
890006
89-M-0006 |
|
January 10, 1989 |
|
|
November 4, 1999 |
April 2, 2018 |
|
- National Institutes of Health Clinical Center, 9000 Rockville Pike
Bethesda, Maryland, United States
|
| 45 |
NCT02607384 |
Active, not recruiting |
The Baltimore Reading and Eye Disease Study |
- Refractive Error
- Visual Impairment
- Convergence Insufficiency
- Reading Disabilities
|
- Behavioral: Eyeglass wearing
- Behavioral: Orthoptic exercises
- Other: Specialist referral
|
Interventional |
Not Applicable |
|
Other |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Other
|
- Prevalence of refractive error and convergence insufficiency among students who perform poorly on reading tests as measured by the Woodcock-Johnson III Tests of Achievement and Gray Oral Reading Test 4 (GORT-4).
- Association between refractive error and convergence insufficiency and reading ability as measured by the Woodcock-Johnson III Tests of Achievement and Gray Oral Reading Test 4 (GORT-4).
- Effect of correction of refractive error and orthoptic exercises on reading ability as measured by the Woodcock-Johnson III Tests of Achievement and Gray Oral Reading Test 4 (GORT-4).
|
400 |
All |
Child, Adult, Senior |
NCT02607384 |
IRB00032063 |
BREDS |
November 2014 |
July 2016 |
December 2018 |
November 18, 2015 |
March 2, 2018 |
|
|
| 46 |
NCT02068261 |
Unknown † |
Working Memory Training in Adults With Substance Abuse and Executive Function Deficits. |
- Substance Abuse
- Executive Dysfunction
- Anxiety
- (and 3 more...)
|
- Behavioral: Computerized Cogmed working memory training
- Behavioral: Treatment as usual
|
Interventional |
Phase 2 |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Treatment
|
- Change from baseline in substance abuse measured with Substance abuse scales in Adult Self Report (ASR; ASEBA).
- Change from baseline in Adult Self Report (ASR; ASEBA) Attention problems scale.
- Change from baseline in Adult Self Report (ASR; ASEBA) Internalizing index.
- (and 8 more...)
|
100 |
All |
18 Years to 70 Years (Adult, Senior) |
NCT02068261 |
RA02 |
|
January 2014 |
December 2016 |
December 2016 |
February 21, 2014 |
October 23, 2015 |
|
- Psychiatric Research Centre
Örebro, Sweden
|
| 47 |
NCT02482350 |
Recruiting |
App-delivered Therapy for Arabic Readers With Hemianopic Alexia |
|
- Behavioral: Reading Training
|
Interventional |
Not Applicable |
- University College London Hospitals
|
Other |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Improvement of reading speed
- Patients will report improvement in static text reading (newspapers, books, letters, etc.) as a function of quality activity of daily living.
- Decrease in the number of fixations
- Decrease in average fixation durations
|
13 |
All |
26 Years to 81 Years (Adult, Senior) |
NCT02482350 |
150817 |
|
July 2015 |
January 2018 |
January 2018 |
June 26, 2015 |
October 25, 2017 |
|
- The Wellington Hospital
London, United Kingdom
|
| 48 |
NCT02127931 |
Active, not recruiting |
Predictive Executive Functioning Models Using Interactive Tangible-Graphical Interface Devices in Adults |
- Attention Deficit Hyperactivity Disorder
|
|
Interventional |
Not Applicable |
|
Industry |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Diagnostic
|
|
100 |
All |
18 Years to 65 Years (Adult) |
NCT02127931 |
|
|
March 2014 |
February 2017 |
|
May 1, 2014 |
August 1, 2016 |
|
- Macalester College
St. Paul, Minnesota, United States
|
| 49 |
NCT01711372 |
Unknown † |
Predictive Executive Functioning Models Using Interactive Tangible-Graphical Interface Devices |
- Attention Deficit Hyperactivity Disorder
|
|
Interventional |
Not Applicable |
|
Industry |
- Allocation: Non-Randomized
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Diagnostic
|
|
34 |
All |
6 Years to 17 Years (Child) |
NCT01711372 |
131209-12 |
|
June 2012 |
December 2015 |
|
October 22, 2012 |
March 13, 2015 |
|
- Groves Academy
St Louis Park, Minnesota, United States - Egli Assessment
Waconia, Minnesota, United States - Senders Pediatrics
Cleveland, Ohio, United States
|
| 50 |
NCT00919906 |
Completed |
My Scrivener® - Measuring Effectiveness and Dose Response in Children |
- Asperger's Syndrome
- Dyslexia
- Cerebral Palsy
- (and 4 more...)
|
|
Interventional |
Phase 1
Phase 2 |
|
Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Treatment
|
- Beery Motor Coordination Subtest
- Print Tool and Cursive Tool
- Deviations from desired 3-D writing path
- Brief Assessment of Fine Motor Skills
|
176 |
All |
5 Years to 19 Years (Child, Adult) |
NCT00919906 |
002
#H133S070082 |
|
April 2009 |
September 2010 |
September 2010 |
June 12, 2009 |
October 28, 2010 |
|
- Susan Palsbo
Eugene, Oregon, United States
|
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