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25 studies found for:    Dravet Syndrome

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Dravet Syndrome (25 records)
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Rank Status Study
1 Available Expanded Access Use of Stiripentol in Dravet Syndrome or Sodium Channel Mutation Epileptic Encephalopathies
Conditions: Dravet Syndrome;   Epileptic Encephalopathies Associated With SCN1A Mutations
Intervention: Drug: Stiripentol
2 No longer available Stiripentol in Dravet Syndrome
Condition: Dravet Syndrome
Intervention: Drug: stiripentol
3 Available Compassionate Use of Stiripentol in Dravet Syndrome
Condition: Dravet Syndrome
Intervention: Drug: Stiripentol
4 Available Treatment Plan to Provide Expanded Access to Stiripentol for Patients With Dravet Syndrome
Condition: Dravet Syndrome
Intervention: Drug: Stiripentol
5 Completed Verapamil as Therapy for Children and Young Adults With Dravet Syndrome
Condition: Dravet Syndrome
Intervention: Drug: Verapamil
6 Completed Antiepileptic Efficacy Study of GWP42003-P in Children and Young Adults With Dravet Syndrome
Conditions: Epilepsy;   Dravet Syndrome
Interventions: Drug: GWP42003-P;   Drug: Placebo control
7 Completed A Dose-ranging Pharmacokinetics and Safety Study of GWP42003-P in Children With Dravet Syndrome
Conditions: Epilepsy;   Dravet Syndrome
Interventions: Drug: GWP42003-P;   Drug: Placebo control
8 Recruiting A Study to Investigate the Efficacy and Safety of Cannabidiol (GWP42003-P) in Children and Young Adults With Dravet Syndrome
Conditions: Epilepsy;   Dravet Syndrome
Interventions: Drug: GWP42003-P;   Drug: Placebo Control
9 Terminated Safety and Tolerability of Clobazam as Adjunctive Therapy in Paediatric Patients Aged ≥1 to ≤16 Years With Dravet Syndrome
Condition: Dravet Syndrome
Intervention: Drug: Clobazam
10 Withdrawn Clobazam as Adjunctive Therapy in Paediatric Patients Aged ≥1 to ≤16 Years With Dravet Syndrome
Condition: Dravet Syndrome
Interventions: Drug: Clobazam;   Drug: Placebo
11 Recruiting Neuronal Excitability of HCN1 Channel Mutations in Dravet Syndrome
Condition: Dravet Syndrome
Intervention: Device: measure of neuronal excitability
12 Enrolling by invitation An Open-Label Extension Trial to Assess the Long-Term Safety of ZX008 (Fenfluramine Hydrochloride HCl) Oral Solution in Children and Young Adults With Dravet Syndrome
Condition: Dravet Syndrome
Intervention: Drug: ZX008 (Fenfluramine Hydrochloride)
13 Recruiting A Trial of Two Fixed Doses of ZX008 (Fenfluramine HCl) in Children and Young Adults With Dravet Syndrome
Conditions: Dravet Syndrome;   Seizure Disorder
Interventions: Drug: ZX008 (Fenfluramine Hydrochloride);   Drug: Matching Placebo
14 Recruiting A Trial of Two Fixed Doses of ZX008 (Fenfluramine HCl) as an Adjunctive Therapy in Children and Young Adults With Dravet Syndrome
Condition: Dravet Syndrome
Interventions: Drug: ZX008 - 0.8 mg/kg/day;   Drug: ZX008 - 0.2 mg/kg/day;   Drug: Placebo
15 Not yet recruiting Cannabidiol Oral Solution as an Adjunctive Therapy for Treatment of Subjects With Inadequately Controlled Dravet Syndrome
Condition: Dravet Syndrome
Interventions: Drug: Cannabidiol Oral Solution;   Drug: Placebo Solution
16 Recruiting Cardiac Arrhythmias in Dravet Syndrome
Condition: Epilepsy
Intervention:
17 Recruiting Genetic Analysis Between Charlotte's Web Responders Versus Non- Responders in a Dravet Population
Condition: Dravet Syndrome
Intervention:
18 Not yet recruiting Ataluren for Nonsense Mutation in CDKL5 and Dravet Syndrome
Condition: Epilepsy
Interventions: Drug: ataluren;   Drug: Placebo
19 Not yet recruiting The Pharmacokinetics of Cannabidiol (CBD) and Its Effects in Children With Severe Epilepsy
Conditions: Dravet Syndrome;   Lennox Gastaut Syndrome
Intervention:
20 Not yet recruiting The Effects of Cannabidiol (CBD) on Electrical and Autonomic Cardiac Function in Children With Severe Epilepsy
Conditions: Lennox-Gastaut Syndrome;   Dravet Syndrome
Interventions: Procedure: 15-Lead ECG;   Drug: Cannabadiol
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† Indicates status has not been verified in more than two years