Comment Period Extended to 3/23/2015 for Notice of Proposed Rulemaking (NPRM) for FDAAA 801 and NIH Draft Reporting Policy for NIH-Funded Trials
175 studies found for:    Darunavir OR Prezista[TREATMENT] AND HIV [CONDITION]
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Rank Status Study
1 Completed
Has Results
Genetic Predictors of Variability in the Drug-drug Interaction Between Darunavir/Ritonavir and Pravastatin
Conditions: HIV Infections;   Hyperlipidemia
Interventions: Drug: Pravastatin;   Drug: Darunavir;   Drug: Ritonavir;   Other: Washout
2 Unknown  Pharmacokinetic Study of Pitavastatin and Ritonavir-Boosted Darunavir or Efavirenz
Conditions: Hyperlipidemia;   HIV
Interventions: Drug: Pitavastatin;   Drug: Darunavir;   Drug: Ritonavir;   Drug: Efavirenz
3 Recruiting A Single-arm, Open-label, Study to Assess the Pharmacokinetics of Darunavir/Ritonavir, Etravirine, and Rilpivirine in HIV-1 Infected Pregnant Women
Conditions: HIV;   HIV Infections;   Pregnancy
Interventions: Drug: TMC114 (darunavir);   Drug: ritonavir;   Drug: TMC125 (etravirine);   Drug: TMC278 (rilpivirine)
4 Completed An Observational Study to Evaluate Tolerability of PREZISTA or INTELENCE in HIV-1 Infected Patients
Condition: Human Immunodeficiency Virus (HIV)
Interventions: Drug: darunavir (PREZISTA);   Drug: etravirine (INTELENCE);   Drug: ritonavir;   Drug: Other antiretroviral medications
5 Completed Study in Healthy Males to Measure Darunavir and Etravirine in Blood, Seminal Fluid, and Rectal Tissue
Conditions: HIV/AIDS;   HIV Infections
Interventions: Drug: darunavir;   Drug: Ritonavir;   Drug: Etravirine
6 Unknown  Darunavir/Ritonavir and Rosuvastatin Pharmacokinetic Study
Condition: HIV Infections
Interventions: Drug: darunavir, ritonavir, rosuvastatin;   Drug: rosuvastatin, darunavir, ritonavir
7 Completed
Has Results
Treatment Simplification by Darunavir/Ritonavir 800/100 mg Once a Day Versus a Triple Combination Therapy With Darunavir/Ritonavir
Conditions: HIV Infections;   AIDS Virus;   Human Immunodeficiency Virus;   Acquired Immunodeficiency Syndrome Virus
Intervention: Drug: darunavir (DRV, TMC114)
8 Completed Pharmacokinetics (PK) Study of Once Daily Darunavir/Ritonavir and Twice and Once Daily Raltegravir in HIV-infected Subjects
Condition: HIV Infections
Intervention: Drug: Raltegravir plus Darunavir/ritonavir
9 Completed Post-prandial Lipid Effects of Raltegravir (RAL) vs Ritonavir -Boosted Darunavir (DRV-r) in Anti-retroviral Therapy (ART)- Naive Adults or Adults Recommencing ART.
Conditions: HIV;   Cardiovascular Disease
Interventions: Drug: raltegravir plus truvada;   Drug: Darunavir, ritonavir, tenofovir/emtricitabine (Truvada)
10 Completed Non-interventional Study on Use of Darunavir With Ritonavir in Clinical Practice
Condition: HIV Infections
Intervention: Drug: darunavir/ritonavir plus background regimen
11 Completed A Study to Assess the Bioequivalence of Darunavir When Co-Administrated With Cobicistat Under Fed and Fasted Conditions
Condition: Healthy Participants
Interventions: Drug: darunavir;   Drug: cobicistat
12 Recruiting Switch to Darunavir/r + Maraviroc Quaque Die in Patients With R5 Tropism by Viral DNA Genotyping (GUSTA)
Condition: HIV Infection
Interventions: Drug: Maraviroc, Darunavir/r;   Drug: current antiretroviral therapy with 3 drugs
13 Active, not recruiting A Clinical Trial Comparing the Efficacy of Darunavir/Ritonavir Monotherapy Versus a Triple Combination Therapy Containing Darunavir/Ritonavir and 2 Nucleoside/Nucleotide Reverse Transcriptase Inhibitors in Patients With Undetectable Plasma HIV-1 RNA on Current Treatment
Conditions: Human Immunodeficiency Virus (HIV) Infections;   Acquired Immunodeficiency Syndrome (AIDS) Virus
Interventions: Drug: Darunavir;   Drug: Ritonavir
14 Completed
Has Results
A Study to Compare Brachial Artery Reactivity and Cardiovascular Risk of a Treatment Simplification by Darunavir/Ritonavir (DRV/r) 800/100 mg Versus a Triple Combination Therapy Containing DRV/r in HIV-1 Infected Patients
Condition: Human Immunodeficiency Virus 1
Interventions: Drug: Darunavir(DRV);   Drug: Ritonavir;   Drug: 2 nucleoside reverse transcriptase inhibitors (NRTIs)
15 Completed Study to Evaluate HIV Viremia and Persistence in Acutely HIV-Infected ARV Naïve Patients Treated With Darunavir/Ritonavir and Etravirine
Conditions: Acute HIV Infection;   HIV Infections
Intervention: Drug: Darunavir/Ritonavir and Etravirine
16 Completed TMC114-C202: A Study of Safety, Efficacy, and Tolerability of TMC114 and Low Dose Ritonavir in HIV-1 Infected Patients
Condition: HIV Infections
Interventions: Drug: TMC114/rtv;   Other: Control Group
17 Completed Darunavir Levels, Virological Efficacy, Proviral ADN and Resistances in Patients on Darunavir/Ritonavir Monotherapy
Condition: HIV-infection
Intervention: Drug: Darunavir/ritonavir
18 Completed A Phase 2 Study to Evaluate Pharmacokinetics, Safety and Efficacy of TMC114/Ritonavir (Rtv) in Human Immunodeficiency Virus (HIV)-1 Infected Children and Adolescents
Conditions: HIV-1;   HIV Infections
Interventions: Drug: TMC114;   Drug: Ritonavir
19 Completed
Has Results
Changes in Triglyceride and Other Lipids (Levels of Fats Found in Blood) When Taking Darunavir Compared to Atazanavir in HIV-infected Patients That Have Never Received Treatment
Condition: HIV
Interventions: Drug: ritonavir;   Drug: darunavir;   Drug: emtricitabine [FTC]/tenofovir [TDF];   Drug: atazanavir
20 Not yet recruiting Immune Recovery in Advanced , ARV-naïve, HIV-1-infected Individuals Taking Dolutegravir or Ritonavir-boosted Darunavir
Condition: Acquired Immune Deficiency Syndrome Virus
Interventions: Drug: Dolutegravir;   Drug: Darunavir/r

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Indicates status has not been verified in more than two years