Comment Period Extended to 3/23/2015 for Notice of Proposed Rulemaking (NPRM) for FDAAA 801 and NIH Draft Reporting Policy for NIH-Funded Trials
219 studies found for:    Coma
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Rank Status Study
21 Terminated Intrathecal Baclofen Therapy and Paroxysmal Dysautonomia in Severe Brain-Injured Patients
Conditions: Traumatic Brain Injury;   Cerebral Anoxia;   Coma;   Hypertonia;   Dysautonomia
Intervention: Drug: baclofen (drug)
22 Completed Microcirculatory Perfusion in Patients With Coma After Out-of-hospital Cardiac Arrest
Condition: Cardiac Arrest
Intervention: Device: microcirculation by SDF and NIRS, in 33 and 36 degrees
23 Completed
Has Results
Visual Performance Investigation of Two Toric Soft Contact Lenses
Conditions: Refractive Error;   Astigmatism;   Myopia;   Hyperopia
Interventions: Device: Lotrafilcon B toric contact lens;   Device: Comfilcon A toric contact lens
24 Completed Mechanical Ventilation in Brain-injured Patients
Conditions: Brain-injury;   Stroke;   Subarachnoid Haemorrhage;   Traumatic Brain Injury;   Structural Coma
Intervention: Other: Pass recommendations on ventilation factors and extubation
25 Recruiting The MENDSII Study, Maximizing the Efficacy of Sedation and Reducing Neurological Dysfunction and Mortality in Septic Patients With Acute Respiratory Failure
Conditions: Sepsis;   Delirium;   Impaired Cognition
Interventions: Drug: Dexmedetomidine;   Drug: Propofol
26 Terminated
Has Results
Use of Conivaptan (Vaprisol) for Hyponatremic Neuro-ICU Patients
Condition: Hyponatremia
Intervention: Drug: Conivaptan
27 Completed
Has Results
Transcranial Direct Current Stimulation in Patients With Disorders of Consciousness
Conditions: Vegetative State;   Minimally Conscious State;   Disorders of Consciousness
Interventions: Device: Anodal tDCS;   Device: sham tDCS
28 Completed FOUR Score in Children With Non-traumatic Impairment of Consciousness
Condition: Impaired Consciousness
Intervention:
29 Completed Pilot Clinical Study of the LRS ThermoSuit™ System in Post Arrest Patients
Conditions: Heart Arrest;   Coma
Intervention: Device: ThermoSuit(R) System
30 Recruiting Finding the Optimal Cooling tempeRature After Out-of-HoSpiTal Cardiac Arrest
Condition: Out-Of-Hospital Cardiac Arrest.
Interventions: Device: Target Temperature Management of 34°C;   Device: Target Temperature Management of 32°C;   Device: Target Temperature Management of 33°C
31 Completed
Has Results
Effectiveness of Amantadine Hydrochloride for Treatment of Severe Traumatic Brain Injury (TBI)
Condition: Traumatic Brain Injury
Interventions: Drug: Amantadine Hydrochloride;   Drug: Placebo
32 Recruiting Pilot Study For Hypothermia Treatment In Hyperammonemic Encephalopathy In Neonates And Very Young Infants
Conditions: Urea Cycle Disorders;   Organic Acidemias
Interventions: Other: Therapeutic Hypothermia;   Other: Standard of care therapy
33 Suspended Antibiotic Prophylaxis for Early Ventilator-associated Pneumonia in Neurological Patients
Condition: Ventilator Associated Pneumonia
Interventions: Drug: Sultamicillin;   Drug: Physiologic Sodium Chloride Solution as placebo
34 Terminated Outcomes Associated With Application of a Normothermia Protocol in Patients With Severe Neurological Insult and Fever
Conditions: Subarachnoid Hemorrhage;   Severe Traumatic Brain Injury
Interventions: Drug: Acetaminophen;   Other: Usual Care;   Drug: Ibuprofen;   Other: Physical Cooling Measures;   Device: Cooling Blanket;   Device: Hydrogel Cooling Pads
35 Active, not recruiting Rehabilitation of Patients After Subarachnoid Hemorrhage
Condition: SAH
Intervention: Other: Early multidisciplinary rehabilitation
36 Unknown  Evaluation of the Efficacy and Safety of Inhaled Nitric Oxide as Adjunctive Treatment for Cerebral Malaria in Children
Condition: Cerebral Malaria
Interventions: Drug: inhaled nitric oxide;   Drug: Placebo
37 Unknown  Vagus Nerve Stimulation to Augment Recovery From Minimally Conscious or Persistently Vegetative States After Traumatic Brain Injury
Conditions: Minimally Conscious States Due to Traumatic Brain Injury;   Persistently Vegetative States Due to Traumatic Brain Injury
Interventions: Device: Vagus nerve stimulation;;   Device: No stimulation
38 Completed Improved ICU Outcomes With Protocolized Management of Analgesia, Sedation and Delirium
Condition: Critical Care
Intervention: Other: protocol
39 Unknown  Acupuncture for Severe Head Injury
Condition: Head Injury
Interventions: Other: acupuncture;   Other: laser acupuncture;   Other: control
40 Unknown  Effectiveness and Safety of Angongniuhuang Pill on Restoring Consciousness for Patients Who Have Suffered From a Stroke
Conditions: Stroke;   Acute Ischemic Stroke
Interventions: Drug: Angongniuhuang Pill;   Drug: placebo

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Indicates status has not been verified in more than two years