Comment Period Extended to 3/23/2015 for Notice of Proposed Rulemaking (NPRM) for FDAAA 801 and NIH Draft Reporting Policy for NIH-Funded Trials
216 studies found for:    Cerebral Atrophy
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Rank Status Study
21 Recruiting Efficacy, Safety and Tolerability of Andrographolides Versus Placebo in Patients With Progressive Forms of MS
Conditions: Primary Progressive Multiple Sclerosis;   Multiple Sclerosis, Secondary Progressive
Interventions: Drug: Andrographolides;   Drug: placebo
22 Recruiting Safety, Tolerability and Activity Study of Ibudilast in Subjects With Progressive Multiple Sclerosis
Conditions: Multiple Sclerosis, Primary Progressive;   Multiple Sclerosis, Secondary Progressive
Interventions: Drug: ibudilast;   Drug: Placebo
23 Recruiting Double Blind Placebo-Controlled Phase I/II Clinical Trial of Idebenone in Patients With Primary Progressive Multiple Sclerosis (IPPoMS)
Condition: Primary Progressive Multiple Sclerosis
Intervention: Drug: Idebenone
24 Terminated
Has Results
Safety and Neuroprotective Effects of Polyphenon E in MS; Phase II
Condition: Multiple Sclerosis
Interventions: Drug: Polyphenon E;   Other: Placebo
25 Completed Safety Study of Natalizumab to Treat Multiple Sclerosis (MS)
Conditions: Relapsing-Remitting Multiple Sclerosis;   Secondary Progressive Multiple Sclerosis
Interventions: Drug: natalizumab;   Other: standard of care
26 Recruiting Amyloid-related Imaging Abnormalities (Microbleeds) in Atypical AD
Conditions: Atypical Alzheimers Disease;   Logopenic Variant of Primary Progressive Aphasia (LPA);   Posterior Cortical Atrophy (PCA)
Intervention: Drug: C-11 PiB
27 Terminated Flupirtine as Oral Treatment in Multiple Sclerosis
Condition: Relapsing Remitting Multiple Sclerosis
Interventions: Drug: Flupirtine;   Drug: Placebo
28 Recruiting Progression Rate of MSA Under EGCG Supplementation as Anti-Aggregation-Approach
Condition: Multiple System Atrophy
Interventions: Drug: EGCG as putative neuroprotective agent;   Drug: Placebo
29 Recruiting The PACO Study ("Personnalité Alzheimer COmportement")
Condition: Alzheimer Disease
Intervention: Behavioral: questioning
30 Recruiting Oculomotor Testing in the Differential Diagnosis of Dementia
Conditions: Lewy Body Disease;   Alzheimer's Disease
Intervention: Other: oculomotor measurements
31 Completed Does Glaucoma Cause Loss of Brain Function?
Condition: Glaucoma
Intervention:
32 Not yet recruiting Automated Brain Morphometry for Dementia Diagnosis
Condition: Dementia
Interventions: Device: Brain Morphometry;   Other: Standard radiological assessment
33 Recruiting Cohort Study to Investigate the Association Between Changes in Brain Volume and Postoperative Cognitive Dysfunction
Conditions: Postoperative Cognitive Dysfunction;   Delirium;   Dementia
Intervention:
34 Completed Efficacy, Safety and Tolerability of Atorvastatin 40 mg in Patients With Relapsing-remitting Multiple Sclerosis Treated With Interferon-beta-1b
Condition: Relapsing-remitting Multiple Sclerosis
Interventions: Drug: Interferon beta-1b group;   Drug: Interferon beta-1b/Atorvastatin group
35 Completed Evaluation of Autologous Mesenchymal Stem Cell Transplantation (Effects and Side Effects) in Multiple Sclerosis
Condition: Multiple Sclerosis
Interventions: Biological: intravenous injection of mesenchymal stem cells;   Biological: injection of cell free media
36 Active, not recruiting Lipoic Acid for Secondary Progressive Multiple Sclerosis (MS)
Condition: Multiple Sclerosis, Chronic Progressive
Interventions: Drug: lipoic acid;   Drug: Placebo
37 Terminated
Has Results
Assessment Study of Steroid Effect in Relapsing Multiple Sclerosis Subjects Treated With Glatiramer Acetate
Condition: Relapsing Remitting Multiple Sclerosis
Interventions: Drug: Glatiramer Acetate;   Drug: Placebo;   Drug: Prednisone
38 Completed Clinical Findings in General Paresis
Condition: General Paresis
Intervention:
39 Unknown  Head Circumference Growth in Children Who Develop Multiple Sclerosis Later in Life
Condition: Multiple Sclerosis
Intervention:
40 Recruiting MS-SMART: Multiple Sclerosis-Secondary Progressive Multi-Arm Randomisation Trial
Condition: Secondary Progressive Multiple Sclerosis
Interventions: Drug: Amiloride;   Drug: Riluzole;   Drug: Fluoxetine;   Drug: Placebo

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Indicates status has not been verified in more than two years