1 |
NCT03213847 |
Recruiting |
Superb Microvascular Imaging of Median Nerve in Carpal Tunnel Syndrome: A Novel Technique in Diagnostic Ultrasound |
- Carpal Tunnel Syndrome Bilateral
|
- Device: Superb microvascular imaging (SMI) (Toshiba)
|
Interventional |
Not Applicable |
|
Other |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Diagnostic
|
- Vascular blood flow images from median nerve (enterrapted in carpal tunnel) obtained with Power Doppler and Superb microvascular imaging.
|
80 |
All |
18 Years to 45 Years (Adult) |
NCT03213847 |
SMI001 |
|
October 20, 2017 |
November 20, 2017 |
November 25, 2017 |
July 11, 2017 |
October 31, 2017 |
|
- University of Usak
Uşak, Turkey
|
2 |
NCT02534493 |
Completed Has Results |
Safety and Efficacy of a Novel Carpal Tunnel Tissue Manipulation Device in Treating Carpal Tunnel Syndrome |
|
- Device: Carpal Tunnel Tissue Manipulation Device (CTMD)
|
Interventional |
Not Applicable |
- Pressure Profile Systems, Inc.
|
Industry |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Change in SSS of the BCTQ at 28 Days vs Baseline
- Change in SSS of the BCTQ 2 Month Post-treatment vs Baseline
|
11 |
All |
21 Years to 65 Years (Adult) |
NCT02534493 |
PPS-CTMD-15-001 |
|
April 2015 |
September 2016 |
September 2016 |
August 27, 2015 |
December 2, 2017 |
December 2, 2017 |
- Mission Pain and Spine
Mission Viejo, California, United States
|
3 |
NCT02907671 |
Recruiting |
Effectiveness of Ultrasound Guided Corticoanesthetic Injection in Carpal Tunnel Syndrome |
|
- Procedure: carpal tunnel corticoanesthetic injection
|
Interventional |
Not Applicable |
- Rehabilitace MUDr. Hasan Mezian s.r.o.
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Triple (Participant, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Visual analogue scale
- Michigan Hand Outcomes Measure
- Boston carpal tunnel questionnaire
- Procedural CAS
|
40 |
All |
18 Years to 70 Years (Adult, Senior) |
NCT02907671 |
111 |
|
October 2016 |
October 2018 |
December 2018 |
September 20, 2016 |
April 19, 2018 |
|
- Kamal Mezian
Litoměřice, Czech Republic, Czechia - Kamal Mezian
Litomerice, Czechia
|
4 |
NCT02792790 |
Active, not recruiting |
Carpal Tunnel Syndrome and Amyloid Cardiomyopathy |
- Amyloidosis
- Cardiomyopathy
- Transthyretin Amyloidosis
- (and 2 more...)
|
|
Observational |
|
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Incidence of transthyretin (TTR) amyloidosis in patients undergoing carpal tunnel release surgery
- Cardiac progression of transthyretin (TTR) amyloidosis in carpal tunnel biopsy-positive patients
- Prevalence of abnormal transthyretin (TTR) kinetics in patients undergoing carpal tunnel surgery
- Early transthyretin (TTR) amyloid cardiomyopathy identification in carpal tunnel biopsy-positive patients
|
96 |
All |
50 Years and older (Adult, Senior) |
NCT02792790 |
16-158 |
|
March 2016 |
May 2021 |
May 2021 |
June 8, 2016 |
January 11, 2018 |
|
- Lutheran Hospital
Cleveland, Ohio, United States
|
5 |
NCT01756820 |
Withdrawn |
Single-portal Endoscopic Carpal Tunnel Release Versus Knifelight for Carpal Tunnel Syndrome. A Randomized Control Trial |
|
- Procedure: Single-portal Endoscopic Carpal Tunnel Release (Microaire®)
- Procedure: Knifelight
|
Interventional |
Phase 2 |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Triple (Participant, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Overall Satisfaction
- Complications
- Pain
- (and 6 more...)
|
0 |
All |
35 Years and older (Adult, Senior) |
NCT01756820 |
Ioannina-CTS-HV |
CTS-HV |
January 2013 |
January 2016 |
January 2016 |
December 27, 2012 |
May 11, 2016 |
|
- University Hospital of Ioannina
Ioannina, Greece
|
6 |
NCT03360344 |
Recruiting |
Non-surgical Intervention for Carpal Tunnel Syndrome |
- Carpal Tunnel Syndrome, Susceptibility to
|
- Device: Kinesio 12 inch Tape
- Device: Kinesio 4 inch Tape
- Device: Cock up Splint and Lumbrical exercises
|
Interventional |
Not Applicable |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Participant)
- Primary Purpose: Other
|
- Numerical Pain Rating Scale (NRS Pain) and Visual Analog Scale for Pain (VAS Pain)
- Grip Strength and Pinch Strength
- Boston Carpal Tunnel Questionnaire
|
78 |
All |
18 Years to 99 Years (Adult, Senior) |
NCT03360344 |
L2017 |
|
February 8, 2018 |
June 2018 |
December 2018 |
December 4, 2017 |
March 7, 2018 |
|
- Loma Linda University
Loma Linda, California, United States
|
7 |
NCT03243227 |
Recruiting |
Effectiveness of Neurodynamic Techniques for the Treatment of Carpal Tunnel Syndrome |
|
- Other: Neurodynamic techniques
- Other: Exercise therapy
|
Interventional |
Not Applicable |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Boston Carpal Tunnel Questionnaire
- The Disabilities of the Arm, Shoulder and Hand (DASH) Score
- Pain severity scale
- (and 2 more...)
|
100 |
All |
18 Years and older (Adult, Senior) |
NCT03243227 |
47/2016/2256 |
|
July 1, 2017 |
July 1, 2018 |
July 1, 2018 |
August 8, 2017 |
October 25, 2017 |
|
- The University of Jordan
Amman, Jordan
|
8 |
NCT03061149 |
Completed |
The Effectiveness of Physical Therapy Modalities in Carpal Tunnel Syndrome |
|
- Other: Low-level laser therapy
- Other: Ultrasound treatment
|
Interventional |
Not Applicable |
- Poznan University of Medical Sciences
|
Other |
- Allocation: Non-Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Investigator)
- Primary Purpose: Treatment
|
- The measurement of hand grip strength in patients with carpal tunnel syndrome after physical therapy
|
70 |
All |
35 Years to 60 Years (Adult) |
NCT03061149 |
1029/08 |
|
March 30, 2009 |
February 15, 2014 |
November 12, 2016 |
February 23, 2017 |
February 23, 2017 |
|
- Poznan University of Medical Sciences
Poznan, Poland
|
9 |
NCT03132051 |
Recruiting |
Sonographic Evaluation of Patients With Carpal Tunnel Syndrome Following Steroid Injection |
|
|
Interventional |
Not Applicable |
- Taipei Veterans General Hospital, Taiwan
|
Other |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Cross sectional area
- flattening ratio
- Boston Carpal Tunnel Questionnaire (BQ)
- (and 4 more...)
|
54 |
All |
18 Years to 80 Years (Adult, Senior) |
NCT03132051 |
2016-07-006A; 2012-05-021A |
|
April 2013 |
February 2018 |
February 2018 |
April 27, 2017 |
April 27, 2017 |
|
- Teipei Veterans General Hospital
Taipei, Taiwan
|
10 |
NCT03476486 |
Completed |
A Pilot Study to Evaluate the Effectiveness of Ultrasound Guided Looped Thread Carpal Tunnel Release |
|
- Procedure: Thread carpal tunnel release
|
Interventional |
Phase 2 |
|
Other |
- Allocation: Non-Randomized
- Intervention Model: Single Group Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Treatment
|
- Early recovery
- Boston Carpal Tunnel Questionnaire
- Hand sensation
- (and 4 more...)
|
20 |
|
Child, Adult, Senior |
NCT03476486 |
Pro00060817 |
|
May 20, 2016 |
January 20, 2018 |
January 20, 2018 |
March 26, 2018 |
March 26, 2018 |
|
|
11 |
NCT01949493 |
Completed |
Non-surgical Treatment of Carpal Tunnel Syndrome by Means of Mechanical Traction |
|
- Device: mechanical traction
- Other: Care as usual
|
Interventional |
Not Applicable |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Change from baseline in symptom severity and functional status on the Boston Carpal Tunnel Questionnaire (BCTQ) at 12 months
- Change from baseline in quality of life on abbreviated version of the World Health Organisation Quality of Life (WHOQOL-BREF)
- Change from baseline in absenteeism from work
- Change from baseline in health care related resource utilization
|
181 |
All |
18 Years to 80 Years (Adult, Senior) |
NCT01949493 |
NL44692.008.13 |
MT-CTS |
October 2013 |
June 2016 |
June 2016 |
September 24, 2013 |
December 9, 2016 |
|
- Viecuri Medisch Centrum
Venlo, Limburg, Netherlands
|
12 |
NCT01887145 |
Completed |
Comparison of Long-term Outcomes Following Endoscopic or Open Surgery for Carpal Tunnel Syndrome |
|
- Procedure: Endoscopic surgery
- Procedure: Open surgery
|
Interventional |
Not Applicable |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Change in CTS symptom severity score
- Rate of repeat surgery
- Change in CTS functional status score
- (and 2 more...)
|
124 |
All |
25 Years to 60 Years (Adult) |
NCT01887145 |
HLM-CTSRCT-2 |
|
September 2013 |
November 2014 |
January 2015 |
June 26, 2013 |
May 6, 2015 |
|
|
13 |
NCT02575729 |
Completed |
Sonography-guided Steroid Injection for Carpal Tunnel Syndrome |
- Carpal Tunnel Syndrome(CTS)
|
|
Interventional |
Phase 3 |
- Chang Gung Memorial Hospital
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Participant)
- Primary Purpose: Treatment
|
- QuickDASH
- Chinese version of Boston symptom and function scale for carpal tunnel syndrome, SS & FS
- Record the neurological symptoms perceived by patient after injection according to their describtion
- (and 4 more...)
|
39 |
All |
18 Years to 80 Years (Adult, Senior) |
NCT02575729 |
NMRPG8A0051 |
|
August 2011 |
July 2014 |
July 2014 |
October 15, 2015 |
October 15, 2015 |
|
|
14 |
NCT02101294 |
Completed Has Results |
Study Protocol for CTS and Keyboard Controlled Randomized Trial |
|
- Device: Interossei Lumbricals Neuro Interface
- Device: Standard QWERTY keyboard
|
Interventional |
Not Applicable |
|
Other |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Prevention
|
- Length of Time Typing QWERTY Prior to Experiencing Symptoms of CTS (Carpal Tunnel Syndrome)
- Length of Time Typing FingerRelief Prior to Experiencing Symptoms of CTS
- Measurement of Wrist Swelling Following Cessation of QWERTY Typing
- Measurement of Increase in Wrist Swelling Following FingerRelief Typing
|
31 |
All |
12 Years to 85 Years (Child, Adult, Senior) |
NCT02101294 |
1997-01 |
|
January 1997 |
July 2008 |
July 2008 |
April 2, 2014 |
September 29, 2014 |
September 29, 2014 |
- Finger Relief
Springfield, Virginia, United States
|
15 |
NCT02587728 |
Recruiting |
Carpal Tunnel/Amyloidosis Blood Sample Study |
- Carpal Tunnel Syndrome
- Amyloidosis
|
|
Observational |
|
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Number of Participants Identified with Amyloidosis
|
500 |
All |
18 Years and older (Adult, Senior) |
NCT02587728 |
20140503 |
|
February 24, 2016 |
November 2020 |
November 2020 |
October 27, 2015 |
February 7, 2018 |
|
- University of Miami
Miami, Florida, United States
|
16 |
NCT03196817 |
Active, not recruiting |
Non-surgical Treatment of Carpal Tunnel Syndrome: Night Splint Versus Local Corticosteroid Infiltration |
|
- Drug: betamethasone dipropionate, betamethasone disodium phosphate and lidocaine 2%
- Device: Wrist splinting
|
Interventional |
Phase 4 |
|
Other |
- Allocation: Randomized
- Intervention Model: Crossover Assignment
- Masking: Single (Investigator)
- Primary Purpose: Treatment
|
- Remission of symptoms
- Boston Questionnaire (Levine)
- Visual Analogue Scale - EVA Pain Evaluation
- Graham Criteria - CTS-6
|
84 |
All |
40 Years and older (Adult, Senior) |
NCT03196817 |
HAMJQ01 |
|
August 1, 2016 |
May 1, 2017 |
December 2017 |
June 23, 2017 |
August 14, 2017 |
|
- Jesus Queiroz junior
São Paulo, Brazil
|
17 |
NCT01972165 |
Completed |
Comparison of Subjective Outcomes and Changes of Ultrasonographic Morphology of Median Nerves of Mini-open and Endoscopic Carpal Tunnel Release in Patients With Idiopathic Carpal Tunnel Syndrome |
- Idiopathic Carpal Tunnel Syndrome
|
- Procedure: Mini-incision carpal tunnel release
- Procedure: Endoscopic carpal tunnel release
|
Interventional |
Not Applicable |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Change of the Boston Carpal Tunnel Questionnaire (BCTQ)
- Change of the Disabilities of the Arm, Shoulder, and Hand (DASH) questionnaire
|
67 |
All |
27 Years to 82 Years (Adult, Senior) |
NCT01972165 |
1-2011-0072 |
|
November 2011 |
July 2013 |
July 2013 |
October 30, 2013 |
October 30, 2013 |
|
- Department of Orthopedic Surgery,Severance Hospital, Yonsei University Health System
Seoul, Korea, Republic of
|
18 |
NCT00987571 |
Completed |
Carpal Tunnel Syndrome: Case Reports and Analysis - Ultrasound Imaging and Pathomechanics of Median Nerve Compression |
|
|
Observational |
|
- EMG Labs of Arizona Arthritis & Rheumatology Associates
|
Other |
- Observational Model: Case Control
- Time Perspective: Prospective
|
- Median nerve compressive narrowing on ultrasound imaging in carpal tunnel syndrome patients
- No median nerve compressive narrowing in normal subjects
|
4 |
All |
18 Years to 90 Years (Adult, Senior) |
NCT00987571 |
CTS-US Med N JAOA |
|
April 2009 |
September 2009 |
September 2009 |
October 1, 2009 |
October 1, 2009 |
|
|
19 |
NCT03031054 |
Recruiting |
The Effect of Hyaluronic Acid for Carpal Tunnel Syndrome |
|
- Procedure: Sono-guided injection with hyaluronic acid
- Procedure: Sono-guided injection with normal saline
|
Interventional |
Not Applicable |
- Tri-Service General Hospital
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Participant, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Change from baseline of pain on 2nd week, 1st, 3rd, 6th month and one year after injection
- Change from baseline of severity of symptoms and functional status on 2nd week, 1st, 3rd, 6th month and one year after injection
- Change from baseline of cross-sectional area of the median nerve on 2nd week, 1st, 3rd, 6th month and one year after injection
- (and 2 more...)
|
60 |
All |
20 Years to 80 Years (Adult, Senior) |
NCT03031054 |
HA for CTS |
|
March 1, 2017 |
May 1, 2019 |
May 1, 2019 |
January 25, 2017 |
April 24, 2018 |
|
- Department of Physical Medicine and Rehabilitation, Tri-Service General Hospital
Tai Chung Municipality, Neihu District, Taiwan - Department of Physical Medicine and Rehabilitation, Tri-Service General Hospital
Taipei, Neihu District, Taiwan
|
20 |
NCT02991001 |
Completed |
The Effect of Hydrodissection for Carpal Tunnel Syndrome |
|
- Procedure: Ultrasound-guided hydrodissection
- Procedure: Placebo ultrasound-guided injection
- Device: Ultrasound
- Drug: Normal Saline
|
Interventional |
Not Applicable |
- Tri-Service General Hospital
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Participant, Investigator)
- Primary Purpose: Treatment
|
- Change from baseline of pain on 2nd week, 1st, 2nd and 3rd month after injection
- Change from baseline of severity of symptoms and functional status on 2nd week, 1st, 2nd and 3rd month after injection
- Change from baseline of cross-sectional area of the median nerve on 2nd week, 1st, 2nd and 3rd month after injection
- (and 2 more...)
|
34 |
All |
20 Years to 80 Years (Adult, Senior) |
NCT02991001 |
Hydrodissection for CTS |
|
January 1, 2017 |
April 15, 2018 |
April 15, 2018 |
December 13, 2016 |
April 24, 2018 |
|
- Department of Physical Medicine and Rehabilitation, Tri-Service General Hospital
Taipei, Neihu District, Taiwan
|
21 |
NCT02609113 |
Completed Has Results |
Static Magnetic Therapy for Carpal Tunnel Syndrome |
|
- Device: Strong Magnetic Wristband
- Device: Weaker Magnetic Wristband
|
Interventional |
Not Applicable |
- Wake Forest University Health Sciences
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Participant, Investigator)
- Primary Purpose: Treatment
|
- Change in Boston Carpal Tunnel Questionnaire (BCTQ) Score at 6 Weeks
- Change in Echogenicity (Hyper or Hypo) on the Median Nerve Ultrasound at 6 Weeks
- Change in Cross-sectional Area as Measured in mm2 on Median Nerve Ultrasound at 6 Weeks
- Change in Vascularity (Normal or Abnormal) as Measured on Median Nerve Ultrasound at 6 Weeks
|
22 |
All |
18 Years and older (Adult, Senior) |
NCT02609113 |
CTS-MAG-22 |
ATTRACT |
August 2015 |
October 21, 2016 |
October 21, 2016 |
November 20, 2015 |
January 16, 2018 |
January 16, 2018 |
- Wake Forest Baptist Health
Winston-Salem, North Carolina, United States
|
22 |
NCT03072290 |
Recruiting |
Corticosteroid Injection in Carpal Tunnel Syndrome |
|
- Drug: Triamcinolone Acetonide
- Drug: lidocaine hydrochloride
|
Interventional |
Not Applicable |
- Taipei Veterans General Hospital, Taiwan
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Participant, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Change from Baseline in the scores on the Boston Carpal Tunnel Questionnaire (BQ).
- Change from Baseline in Median nerve distal motor latency
- Change from Baseline in sensory nerve conduction velocity
- (and 2 more...)
|
60 |
All |
18 Years and older (Adult, Senior) |
NCT03072290 |
2016-07-006A |
|
March 2017 |
June 2018 |
September 2018 |
March 7, 2017 |
March 7, 2017 |
|
- Taipei veteran general hospital
Taipei, Taiwan
|
23 |
NCT03499158 |
Completed New |
Terminal Latency Index, Residual Latency and Median Ulnar F Latency Difference in Carpal Tunnel Syndrome |
|
- Other: nerve conduction study
|
Observational |
|
- ASLIHAN UZUNKULAOGLU
- Baskent University
- Ufuk University
|
Other |
- Observational Model: Other
- Time Perspective: Retrospective
|
|
160 |
All |
18 Years to 90 Years (Adult, Senior) |
NCT03499158 |
KA15/280 |
|
January 1, 2016 |
March 1, 2016 |
March 2, 2016 |
April 17, 2018 |
April 17, 2018 |
|
|
24 |
NCT02990962 |
Completed |
The Effect of Perineural Injection Therapy Versus Steroid in Patients With Carpal Tunnel Syndrome |
|
- Drug: 5% dextrose
- Drug: 1cc 2% Xylocaine+4cc Triamcinolone (40mg)
|
Interventional |
Not Applicable |
- Tri-Service General Hospital
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Participant, Investigator)
- Primary Purpose: Treatment
|
- Change from baseline of pain on 2nd week, 1st, 2nd, 3rd and 6 month after the treatment.
- Change from baseline of severity of symptoms and functional status on 2nd week, 1st, 2nd, 3rd and 6 month after the treatment.
- Change from baseline of cross-sectional area of the median nerve on 2nd week, 1st, 2nd, 3rd and 6 month after the treatment.
- Change from baseline of nerve conduction velicity on 2nd week, 1st, 2nd, 3rd and 6 month after the treatment.
|
54 |
All |
20 Years to 80 Years (Adult, Senior) |
NCT02990962 |
PIT for CTS |
|
December 2016 |
April 1, 2018 |
April 1, 2018 |
December 13, 2016 |
April 24, 2018 |
|
- Department of Physical Medicine and Rehabilitation, Tri-Service General Hospital
Taipei, Neihu District, Taiwan
|
25 |
NCT02278289 |
Completed |
Comparative Effectiveness of Ultrasound and Paraffin Therapy in Patients With Carpal Tunnel Syndrome: A Randomized Trial |
|
- Device: ultrasound
- Procedure: paraffin therapy
|
Interventional |
Not Applicable |
- Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation
- National Science Council, Taiwan
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- functional status scale of the Boston carpal tunnel syndrome questionnaire
- symptom severity scale of the Boston carpal tunnel syndrome questionnaire
- pain scale
- (and 4 more...)
|
60 |
All |
18 Years and older (Adult, Senior) |
NCT02278289 |
BuddhistTCGHTaipei |
|
January 2010 |
December 2011 |
December 2011 |
October 29, 2014 |
October 29, 2014 |
|
|
26 |
NCT02382328 |
Completed |
Alpha Lipoic Acid on Clinical and Electrophysiological Recovery in Carpal Tunnel Syndrome Undergoing Surgical Release |
|
- Drug: alpha lipoic acid
- Drug: Placebo
|
Interventional |
Phase 2 |
- Hospital Civil de Guadalajara
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Participant, Investigator)
- Primary Purpose: Treatment
|
- median nerve sensory latency (using nerve conduction studies to determine median sensory latency.)
- cross sectional area of median nerve (sonographic measurement to determine cross sectional area of median nerve.)
|
40 |
All |
18 Years and older (Adult, Senior) |
NCT02382328 |
265/14 |
|
February 2016 |
June 2016 |
July 2016 |
March 6, 2015 |
August 9, 2016 |
|
- Antiguo Hospital Civil de Guadalajara Fray Antonio Alcalde
Guadalajara, Jalisco, Mexico
|
27 |
NCT02652390 |
Completed |
Local Steroid Injection vs Placebo in Carpal Tunnel Syndrome |
|
- Drug: Methylprednisolone 80 mg
- Drug: Methylprednisolone 40 mg
- Other: Saline
|
Interventional |
Phase 4 |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Proportion of patients who have had carpal tunnel release surgery on the study
- Symptom severity score
- Palmar pain score
- (and 3 more...)
|
111 |
All |
18 Years to 70 Years (Adult, Senior) |
NCT02652390 |
HLM_CTS_2 |
|
February 2016 |
October 2016 |
October 2016 |
January 11, 2016 |
September 27, 2017 |
|
|
28 |
NCT00981565 |
Completed |
Mild Carpal Tunnel Syndrome |
|
- Procedure: open carpal tunnel release
- Other: Night-cast
|
Interventional |
Not Applicable |
- North Karelia Central Hospital
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Change in Symptom Severity Score
- Pain Visual Analogue Scale (VAS)
- Change in electroneuromyography
|
88 |
All |
18 Years to 65 Years (Adult) |
NCT00981565 |
NKCH-Surg-005 |
|
September 2009 |
September 2011 |
June 2012 |
September 22, 2009 |
October 18, 2012 |
|
- North-Carelia Central Hospital
Joensuu, Finland - Kuopio University Hospital
Kuopio, Finland - Central Hospital of Mikkeli
Mikkeli, Finland
|
29 |
NCT02495298 |
Completed |
Fascial Manipulation on the Treatment of Carpal Tunnel Syndrome |
|
- Procedure: Fascial Manipulation
- Procedure: Sham Fascial Manipulation
|
Interventional |
Phase 2 |
- Marta Imamura
- University of Sao Paulo
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Triple (Participant, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Change from baseline in pain on the VAS score for pain at 10 days after the end of the treatment.
- Change from baseline in pain on the VAS score for pain at 3 months after the end of the treatment.
- Change from baseline in function on BCTQ score for function at 10 days and 3 months after the end of the treatment.
- (and 2 more...)
|
14 |
All |
18 Years to 65 Years (Adult) |
NCT02495298 |
Fascial Manipulation on CTS |
|
August 2013 |
December 2013 |
April 2014 |
July 13, 2015 |
October 5, 2016 |
|
- Instituto de Medicina Fisica e Reabilitacao HCFMUSP
Sao Paulo, Brazil
|
30 |
NCT02809261 |
Completed |
The Effect of Perineural Injection Therapy in Patients With Carpal Tunnel Syndrome |
|
- Procedure: Ultrasound-guided perineural injection with 5% dextrose
- Procedure: Ultrasound-guided perineural injection with normal saline
- Drug: Normal Saline
- Drug: 5% Dextrose
|
Interventional |
Not Applicable |
- Tri-Service General Hospital
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Participant, Investigator)
- Primary Purpose: Treatment
|
- Change from baseline of pain on 2nd, 4th, 8th, 12th, 16th and 24th weeks after treatment.
- Change from baseline in severity of symptoms and functional status on 2nd, 4th, 8th, 12th, 16th and 24th weeks after treatment.
- Change from baseline in cross-sectional area of the median nerve on 2nd, 4th, 8th, 12th, 16th and 24th weeks after treatment.
|
60 |
All |
20 Years to 85 Years (Adult, Senior) |
NCT02809261 |
TSGHIRB No: 2-105-05-033 |
|
May 1, 2016 |
March 30, 2017 |
March 30, 2017 |
June 22, 2016 |
December 19, 2017 |
|
- Department of Physical Medicine and Rehabilitation, Tri-Service General Hospital
Taipei, Neihu District, Taiwan
|
31 |
NCT03427983 |
Recruiting |
Hydrodissection as a Treatment for Carpal Tunnel Syndrome |
|
- Procedure: Hydrodissection
- Procedure: Regular Injection
|
Interventional |
Not Applicable |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Triple (Participant, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Tolerance
- Clinical Severity of Carpal Tunnel Syndrome
- Overall Pain
- Additional Treatment
|
20 |
All |
21 Years to 80 Years (Adult, Senior) |
NCT03427983 |
17-009840 |
|
March 8, 2018 |
July 31, 2018 |
January 1, 2019 |
February 9, 2018 |
March 22, 2018 |
|
- Mayo Clinic in Rochester
Rochester, Minnesota, United States
|
32 |
NCT01789645 |
Active, not recruiting |
Physical Therapy in Carpal Tunnel Syndrome |
|
- Other: Conservative group
- Procedure: Surgical group
|
Interventional |
Not Applicable |
- Universidad Rey Juan Carlos
- Hospital Universitario Fundación Alcorcón
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Treatment
|
- Changes in the intensity of pain symptoms between baseline and follow-up periods
- Changes in patients self-perceived improvement between baseline and follow-up periods
- Changes in function between baseline and follow-up periods
- Changes in severity of the symptoms between baseline and follow-up periods
|
120 |
Female |
18 Years to 65 Years (Adult) |
NCT01789645 |
PI01223 |
|
February 2013 |
January 2014 |
August 2018 |
February 12, 2013 |
October 31, 2017 |
|
- Universidad Rey Juan Carlos - Hospital Universitario Fundación Alcorcon
Alcorcon, Madrid, Spain
|
33 |
NCT02698085 |
Completed |
Diacutaneous Fibrolysis on Carpal Tunnel Syndrome |
|
- Other: Actual Diacutaneous Fibrolysis
- Other: Sham Diacutaneous Fibrolysis
|
Interventional |
Not Applicable |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Participant, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Intensity symptoms pre-intervention with a visual analogic scale
- Intensity symptoms post-intervention with a visual analogic scale
- Intensity symptoms after month with a visual analogic scale
- (and 7 more...)
|
60 |
All |
18 Years to 65 Years (Adult) |
NCT02698085 |
C.I.PI14/00086 |
|
April 1, 2016 |
September 1, 2016 |
October 10, 2016 |
March 3, 2016 |
November 21, 2017 |
|
- Sandra Jiménez
Zaragoza, Spain
|
34 |
NCT02054247 |
Completed |
Continuous And Pulsed Ultrasound Treatments On Carpal Tunnel Syndrome |
|
- Device: ultrasound
- Device: pulsed ultrasound
- Device: placebo ultrasound
|
Interventional |
Not Applicable |
- Eskisehir Osmangazi University
|
Other |
- Allocation: Randomized
- Intervention Model: Factorial Assignment
- Masking: Double (Participant, Investigator)
- Primary Purpose: Treatment
|
- Change from baseline in symptom severity with Symptom Severity Scale
- Change from baseline in pain with Visual Analogue Scale
- Change from baseline in functional status with Functional Status Scale
- Chances from baseline median nerve motor and sensory conduction velocity and distal latencies
|
46 |
Female |
Child, Adult, Senior |
NCT02054247 |
clinics-2013-0627 |
|
October 2011 |
June 2013 |
June 2013 |
February 4, 2014 |
February 4, 2014 |
|
|
35 |
NCT02870673 |
Not yet recruiting |
Assessment of the Effectiveness of Ultrasound-guided Acupuncture in the Management of Carpal Tunnel Syndrome |
|
- Drug: SHINCORT
- Drug: XYLOCAINE
- Device: sham electroacupuncture
- Device: electroacupuncture
|
Interventional |
Phase 2 Phase 3 |
- Taipei Medical University Hospital
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Participant, Outcomes Assessor)
- Primary Purpose: Treatment
|
- pain assessed on visual analog scale
- Boston Carpal Tunnel Syndrome Questionaire
- The 6-item CTS symptoms scale
- (and 7 more...)
|
72 |
All |
20 Years and older (Adult, Senior) |
NCT02870673 |
N201605074 |
|
August 2016 |
August 2017 |
September 2017 |
August 17, 2016 |
August 19, 2016 |
|
|
36 |
NCT02708693 |
Completed |
Efficacy of Combined Ultrasound Guided Steroid Injection and Splinting in Patients With Carpal Tunnel Syndrome |
|
- Drug: Triamcinolone Acetonide
- Device: thermoplastic wrist splint
- Drug: lidocaine hydrochloride
|
Interventional |
Not Applicable |
- Taipei Veterans General Hospital, Taiwan
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Participant)
- Primary Purpose: Treatment
|
- Change from Baseline in the scores on the Boston Carpal Tunnel Questionnaire (BQ).
- Change from Baseline in Median nerve distal motor latency
- Change from Baseline in sensory nerve conduction velocity
- (and 5 more...)
|
52 |
All |
18 Years and older (Adult, Senior) |
NCT02708693 |
2012-05-021A |
|
April 2013 |
April 2014 |
June 2014 |
March 15, 2016 |
March 15, 2016 |
|
|
37 |
NCT02218229 |
Completed |
The Effect of Extracorporeal Shock Wave Therapy on Carpal Tunnel Syndrome |
|
|
Interventional |
Not Applicable |
- Tri-Service General Hospital
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Participant, Investigator)
- Primary Purpose: Treatment
|
- Change from baseline of pain on1st, 2nd, 4th, 8th,12th and 16th weeks after treatment.
- Change from baseline in severity of symptoms and functional status on 1st, 2nd, 4th, 8th,12th and 16th weeks after treatment.
- Change from baseline in cross-sectional area of the median nerve on 1st, 2nd, 4th, 8th, 12th and 16th weeks after treatment.
- (and 2 more...)
|
60 |
All |
18 Years to 80 Years (Adult, Senior) |
NCT02218229 |
TSGHIRB: 1-102-05-122 |
|
August 2014 |
May 2017 |
May 2017 |
August 18, 2014 |
October 11, 2017 |
|
- Tri-Service General Hospital, School of Medicine, National Defense Medical Center
Taipei, Neihu, Taiwan
|
38 |
NCT02514317 |
Completed |
Percutaneous Treatment of Carpal Tunnel Syndrome With Scan |
|
- Procedure: percutaneous treatment
- Device: Ultrasound
|
Interventional |
Phase 2 |
- University Hospital, Caen
|
Other |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Pain (visual analogic scale)
- paresthesia
- muscle strength (dynamometer JAMARD)
|
40 |
|
18 Years and older (Adult, Senior) |
NCT02514317 |
11-058 |
ECHOCARPE |
January 2012 |
March 2013 |
April 2013 |
August 3, 2015 |
August 3, 2015 |
|
- University Hospital
Caen, France
|
39 |
NCT03184688 |
Recruiting |
Platelet Rich Plasma for Carpal Tunnel Syndrome |
|
- Procedure: platelet rich plasma
- Drug: Normal saline
|
Interventional |
Not Applicable |
- Tri-Service General Hospital
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Participant, Investigator)
- Primary Purpose: Treatment
|
- Change from baseline of pain on 2nd week, 1st, 3rd, 6th month and one year after the treatment.
- Change from baseline in severity of symptoms and functional status on 2nd week, 1st, 3rd, 6th month and one year after the treatment.
- Change from baseline in cross-sectional area of the median nerve on 2nd week, 1st, 3rd, 6th month and one year after the treatment.
- (and 2 more...)
|
30 |
All |
20 Years to 80 Years (Adult, Senior) |
NCT03184688 |
Perineural PRP for CTS |
|
September 8, 2017 |
January 30, 2019 |
January 30, 2019 |
June 14, 2017 |
September 11, 2017 |
|
- Department of Physical Medicine and Rehabilitation, Tri-Service General Hospital
Taipei, Neihu District, Taiwan
|
40 |
NCT02219919 |
Completed |
Nociceptive Gain Processing After Physical Therapy in Carpal Tunnel Syndrome |
|
- Other: Surgical Group
- Other: Physical Therapy Group
|
Interventional |
Not Applicable |
- Universidad Rey Juan Carlos
- Hospital Universitario Fundación Alcorcón
- Hospital San Carlos, Madrid
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Triple (Participant, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Changes in widespread pressure pain thresholds between baseline and follow-up periods
- Changes in heat and cold pain thresholds between baseline and follow-up periods
- Changes in pain intensity between baseline and follow-ups periods
|
100 |
Female |
18 Years to 65 Years (Adult) |
NCT02219919 |
HUFA-12/14 |
|
August 2014 |
May 2016 |
May 2016 |
August 19, 2014 |
May 12, 2016 |
|
- Hospital Universitario Fundación Alcorcon
Alcorcón, Madrid, Spain - Universidad Rey Juan Carlos
Alcorcón, Madrid, Spain
|
41 |
NCT02830828 |
Recruiting |
Studying Finger-thumb Grip in Patients With Carpal Tunnel Syndrome |
|
- Other: Investigation of precision pinch grip control
|
Observational |
|
- Thomas Edward Pidgeon
- University of Birmingham
- University Hospital Birmingham NHS Foundation Trust
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Change in Precision Pinch Grip Force measured during a pinch-hold up activity over time during follow-up
|
35 |
All |
18 Years to 80 Years (Adult, Senior) |
NCT02830828 |
RRK5257 |
|
March 2015 |
September 2017 |
September 2017 |
July 13, 2016 |
June 6, 2017 |
|
- University Hospitals Birmingham Queen Elizabeth
Birmingham, West Midlands, United Kingdom
|
42 |
NCT00701233 |
Active, not recruiting |
Botulinum Toxin for Carpal Tunnel Syndrome |
|
- Drug: Botulinum toxin
- Drug: Corticosteroid injection into Carpal Tunnel
|
Interventional |
Phase 2 |
- University of Minnesota - Clinical and Translational Science Institute
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Visual Analog Scale
- Carpal Tunnel Syndrome Assessment Questionnaire
|
20 |
All |
18 Years and older (Adult, Senior) |
NCT00701233 |
0708M13705 |
|
June 2012 |
May 2018 |
June 2018 |
June 19, 2008 |
June 29, 2017 |
|
- University of Minnesota PM&R Department
Minneapolis, Minnesota, United States
|
43 |
NCT02986828 |
Recruiting |
Platelet Rich Plasma and Hydrodissection for Carpal Tunnel Syndrome |
|
- Drug: platelet rich plasma
- Drug: Normal saline
- Device: Ultrasound
|
Interventional |
Not Applicable |
- Tri-Service General Hospital
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Participant, Investigator)
- Primary Purpose: Treatment
|
- Change from baseline of pain on 2nd week, 1st, 3rd, 6th month and 1 year after injection
- Change from baseline of severity of symptoms and functional status on 2nd week, 1st, 3rd, 6th month and 1 year after injection
- Change from baseline of cross-sectional area of the median nerve on 2nd week, 1st, 3rd, 6th month and 1 year after injection
- (and 2 more...)
|
30 |
All |
20 Years to 80 Years (Adult, Senior) |
NCT02986828 |
PRP and hydrodissection |
|
December 2016 |
December 2018 |
December 2018 |
December 8, 2016 |
December 19, 2017 |
|
- Department of Physical Medicine and Rehabilitation, Tri-Service General Hospital
Taipei, Neihu District, Taiwan
|
44 |
NCT02553811 |
Completed |
Diagnosis of Carpal Tunnel Syndrome: Effectiveness of Diagnostic Tests. Clinical Trial of Accuracy |
- Carpal Tunnel Syndrome
- Compression Neuropathy, Carpal Tunnel
- Median Neuropathy, Carpal Tunnel
|
- Diagnostic Test: accuracy diagnostic
|
Interventional |
Not Applicable |
- Federal University of São Paulo
|
Other |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Diagnostic
|
- Accuracy of the ultrasonography (US)
- Accuracy of the electromyograph (EMG)
- Life quality
- Improvement in severity of symptoms and functional status of the patients
|
115 |
Female |
40 Years to 80 Years (Adult, Senior) |
NCT02553811 |
244468 |
DCTS |
October 2015 |
June 2016 |
October 2016 |
September 18, 2015 |
July 14, 2017 |
|
- Hospital Regional do Vale do Paraiba
Taubate, São Paulo, Brazil
|
45 |
NCT02233660 |
Completed |
The Role of the Cervical Spine in Carpal Tunnel Syndrome |
|
- Other: Physical Therapy Group
- Procedure: Surgical Group
|
Interventional |
Not Applicable |
- Universidad Rey Juan Carlos
- Hospital Universitario Fundación Alcorcón
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Changes in hand function between baseline and follow-up periods
- Changes in active cervical range of motion between baseline and follow-up periods
- Changes in pinch grip force between baseline and follow-up periods
|
100 |
Female |
18 Years to 65 Years (Adult) |
NCT02233660 |
HUFA PI -12/0023 |
|
September 2014 |
March 2016 |
March 2016 |
September 8, 2014 |
March 15, 2016 |
|
- Hospital Universitario Fundación Alcorcon
Alcorcon, Madrid, Spain - Universidad Rey Juan Carlos
Alcorcon, Madrid, Spain
|
46 |
NCT00803257 |
Completed |
Effect of Lumbrical Stretching on Carpal Tunnel Syndrome |
|
- Other: Lumbrical splint and Lumbrical exercises
|
Interventional |
Not Applicable |
- University of Pittsburgh
- Arthritis Foundation
|
Other |
- Allocation: Randomized
- Intervention Model: Factorial Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Treatment
|
- Carpal Tunnel Syndrome Symptom Severity and Functional Status Scale (CTS-SSFS)
|
124 |
All |
18 Years and older (Adult, Senior) |
NCT00803257 |
07030166 |
|
March 2008 |
January 2011 |
January 2011 |
December 5, 2008 |
June 13, 2012 |
|
- University of Pittsburgh
Pittsburgh, Pennsylvania, United States
|
47 |
NCT02696161 |
Completed |
Platelet Rich Plasma and Perineural Injection Therapy for Carpal Tunnel Syndrome |
|
- Other: platelet rich plasma
- Other: 5% dextrose
|
Interventional |
Not Applicable |
- Tri-Service General Hospital
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Participant, Investigator)
- Primary Purpose: Treatment
|
- Change from baseline of pain on 2nd, 4th, 8th, 12th, 16th and 24th weeks after treatment.
- Change from baseline in severity of symptoms and functional status on 2nd, 4th, 8th, 12th, 16th and 24th weeks after treatment.
- Change from baseline in cross-sectional area of the median nerve on 2nd, 4th, 8th, 12th, 16th and 24th weeks after treatment.
- (and 2 more...)
|
43 |
All |
20 Years to 80 Years (Adult, Senior) |
NCT02696161 |
PRP for CTS |
|
February 1, 2016 |
July 31, 2017 |
July 31, 2017 |
March 2, 2016 |
April 25, 2018 |
|
- Department of Physical Medicine and Rehabilitation, Tri-Service General Hospital
Taipei, Neihu District, Taiwan
|
48 |
NCT03299361 |
Completed |
Diffusion Tensor Imaging of the Median Nerve Before and After Carpal Tunnel Corticosteroid Injection in Patients With Carpal Tunnel Syndrome: Feasibility Study |
|
- Other: Magnetic resonance image (MRI)
|
Observational |
|
- Tri-Service General Hospital
|
Other |
- Observational Model: Case-Only
- Time Perspective: Prospective
|
- Inter-scan change of DTI at baseline and 2 weeks after injection
- Correlation of Inter-scan change of DTI with symptoms relief
|
12 |
All |
Child, Adult, Senior |
NCT03299361 |
TSGHIRB 1-105-05-056 |
|
May 26, 2016 |
December 31, 2016 |
March 7, 2017 |
October 3, 2017 |
October 3, 2017 |
|
|
49 |
NCT02217293 |
Completed |
Efficacy of Pulsed Radiofrequency of the Median Nerve Under Ultrasound Guidance in Patients With Carpal Tunnel Syndrome |
|
- Device: Pulsed Radiofrequency
|
Interventional |
Not Applicable |
- Tri-Service General Hospital
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Treatment
|
- Change from baseline of pain on1st, 4th, 8th and 12th weeks after treatment.
- Change from baseline in severity of symptoms and functional status on 1st, 4th, 8th and 12th weeks after treatment.
- Change from baseline in cross-sectional area of the median nerve on 1st, 4th, 8th and 12th weeks after treatment.
- (and 2 more...)
|
44 |
All |
18 Years to 80 Years (Adult, Senior) |
NCT02217293 |
TSGHIRB: 1-101-05-049 |
|
November 2012 |
September 2013 |
September 2013 |
August 15, 2014 |
August 15, 2014 |
|
- Tri-Service General Hospital, School of Medicine, National Defense Medical Center
Taipei, Neihu, Taiwan
|
50 |
NCT03180125 |
Recruiting |
Hyaluronic Acid Hydro-dissection Use in Idiopathic Carpal Tunnel Syndrome Guided by Ultrasonic Study |
|
- Drug: Sodium Hyaluronate
- Device: ultrasound
- Drug: Sodium Hyaluronate and 1% lidocain
- Drug: Corticosteroid and 1%lidocain
|
Interventional |
Phase 1 |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Investigator)
- Primary Purpose: Treatment
|
- neuropathic pain VAS
- nerve conduction study
|
50 |
All |
18 Years and older (Adult, Senior) |
NCT03180125 |
Hyaluronic injection |
|
August 15, 2017 |
October 1, 2017 |
March 2018 |
June 8, 2017 |
February 20, 2018 |
|
- Assiut governorate
Assiut, Egypt
|