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713 studies found for:    Camptothecin
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Rank Status Study
1 Completed Phase I and Pharmacology Study of Camptothecin-20-O-Propionate Hydrate (CZ48) in Patients With Solid Tumors or Lymphoma
Conditions: Advanced Solid Tumors;   Lymphomas
Intervention: Drug: Camptothecin-20-O-Propionate Hydrate (CZ48)
2 Enrolling by invitation Safety Study of Camptothecin-20-O-Propionate Hydrate (CZ48)
Conditions: Malignant Lymphoma of Extranodal and/or Solid Organ Site;   Solid Tumor
Intervention: Drug: CZ48
3 Completed Aerosolized Liposomal Camptothecin in Patients With Metastatic or Recurrent Cancer of the Endometrium or the Lung
Conditions: Corpus Uteri;   Lung Cancer
Intervention: Drug: 9-NC in aerosol reservoir
4 Completed Study of Aerosolized Liposomal 9-Nitro-20 (S)- Camptothecin (L9NC)
Conditions: Lung Diseases;   Cancer
Intervention: Drug: Liposomal 9-Nitrocamptothecin
5 Terminated Topotecan Hydrochloride or Cyclodextrin-Based Polymer-Camptothecin CRLX101 in Treating Patients With Recurrent Small Cell Lung Cancer
Conditions: Extensive Stage Small Cell Lung Cancer;   Recurrent Small Cell Lung Cancer
Interventions: Drug: topotecan hydrochloride;   Drug: cyclodextrin-based polymer-camptothecin CRLX101
6 Recruiting Trial of CRLX101, a Nanoparticle Camptothecin With Olaparib in People With Relapsed/Refractory Small Cell Lung Cancer
Conditions: Solid Tumors;   Small Cell Lung Carcinoma;   Carcinoma, Non-Small-Cell Lung;   Lung Neoplasms
Interventions: Drug: CRLX101;   Drug: olaparib
7 Completed Polyglutamate Camptothecin in Treating Patients With Advanced Cancer
Condition: Unspecified Adult Solid Tumor, Protocol Specific
Intervention: Drug: polyglutamate camptothecin
8 Withdrawn Pharmacology Study of Aerosolized Liposomal
Conditions: Lung Diseases;   Cancer
Intervention: Drug: L9NC: Liposomal 9-Nitro-20 (S)-Camptothecin
9 Terminated Efficacy of Pegamotecan (PEG-Camptothecin) in Localized or Metastatic Cancer of the Stomach or Gastroesophageal Junction
Conditions: Cancer of Stomach;   Gastroesophageal Cancer
Intervention: Drug: Pegamotecan
10 Completed Phase II Study of Aerosolized Liposomal 9-Nitro-20 (S)- Camptothecin (L9NC)
Conditions: Corpus Uteri;   Endometrial Cancer
Intervention: Drug: 9-NC in aerosol reservoir
11 Completed Pharmacology Study of Aerosolized Liposomal 9-Nitro-20 (S)-Camptothecin (L9NC)
Conditions: Corpus Uteri;   Endometrial Cancer
Intervention:
12 Completed Pilot Trial of CRLX101 in Treatment of Patients With Advanced or Metastatic Stomach, Gastroesophageal, or Esophageal Cancer That Cannot be Removed by Surgery
Conditions: Adenocarcinoma of the Esophagus;   Adenocarcinoma of the Gastroesophageal Junction;   Diffuse Adenocarcinoma of the Stomach;   Intestinal Adenocarcinoma of the Stomach;   Mixed Adenocarcinoma of the Stomach;   Recurrent Esophageal Cancer;   Recurrent Gastric Cancer;   Squamous Cell Carcinoma of the Esophagus;   Stage IIIB Esophageal Cancer;   Stage IIIB Gastric Cancer;   Stage IIIC Esophageal Cancer;   Stage IIIC Gastric Cancer;   Stage IV Esophageal Cancer;   Stage IV Gastric Cancer
Interventions: Drug: cyclodextrin-based polymer-camptothecin CRLX101;   Other: Laboratory biomarker analysis;   Other: Pharmacological studies
13 Completed Aerosol L9-NC and Temozolomide in Ewing's Sarcoma
Condition: Ewing's Sarcoma
Interventions: Drug: Temozolomide;   Drug: L9-NC
14 Completed ST1968 Intravenous (Weekly) in Solid Tumors
Condition: Solid Tumors
Intervention: Drug: ST1968
15 Unknown  Study of AR-67 in Adult Patients With Recurrence of Glioblastoma Multiforme (GBM) or Gliosarcoma
Conditions: Glioblastoma Multiforme;   GBM;   Gliosarcoma
Intervention: Drug: AR-67 (7-t-butyldimethylsiltyl-10-hydroxy-camptothecin)
16 Completed Study of CRLX101 (Formerly Named IT-101) in the Treatment of Advanced Solid Tumors
Conditions: Cancer;   Solid Tumor
Intervention: Drug: Camptothecin (CPT) conjugated to a linear, cyclodextrin-based polymer
17 Suspended Efficacy and Safety Evaluation of Pegamotecan (PEG-camptothecin) in Advanced or Metastatic Soft Tissue Sarcoma
Condition: Sarcoma, Soft Tissue
Intervention: Drug: Pegamotecan
18 Completed High Dose Camptothecin-11 (CPT-11) in Recurrent Unresectable Malignant Glioma
Condition: Malignant Glioma
Intervention: Drug: Irinotecan (Camptosar, CPT-11)
19 Completed Phase I/II CT 2106 and 5-FU/FA in Colorectal Cancer
Condition: Colorectal Cancer
Interventions: Drug: CT-2106;   Drug: Folinic acid;   Drug: 5-FU (fluorouracil)
20 Completed A Phase 2 Study of CRLX101 in Patients With Advanced Non-Small Cell Lung Cancer
Condition: Non-Small Cell Lung Cancer
Interventions: Drug: CRLX101;   Other: Best Supportive Care

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Study has passed its completion date and status has not been verified in more than two years.