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78 studies found for:    CXCR4
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Rank Status Study
1 Suspended Imaging CXCR4 Expression in Subjects With Cancer Using 64 Cu-Plerixafor
Condition: Cancer
Intervention: Drug: 64-Cu-plerixafor
2 Recruiting Correlation of CXCR4 Expression in Premature Infants With a Diagnosis of Autism at 24 Months
Conditions: Autism Spectrum Disorder;   Complication of Prematurity
Intervention:
3 Recruiting Autologous CD4 T-Cells in HIV (C34-CXCR4)
Condition: Hiv
Intervention: Biological: Autologous CD4 T-Cells
4 Completed Safety Study of a Chemokine Receptor (CXCR4) Antagonist in Multiple Myeloma Patients
Condition: Multiple Myeloma
Intervention: Drug: BKT140
5 Completed CXCR4 Antagonism for Cell Mobilisation and Healing in Acute Myocardial Infarction (CATCH-AMI)
Condition: Large Reperfused ST-Elevation Myocardial Infarction
Interventions: Drug: POL6326;   Drug: Placebo
6 Completed Anti-CXCR4 (BMS-936564) Alone and in Combination With Lenalidomide/Dexamethasone or Bortezomib/Dexamethasone in Relapsed/Refractory Multiple Myeloma
Condition: Multiple Myeloma
Interventions: Biological: Anti-CXCR4 (BMS-936564);   Biological: Lenalidomide;   Biological: Dexamethasone;   Biological: Bortezomib
7 Withdrawn Imatinib and BL-8040 (Novel Anti CXCR4 Antagonist) for Improving Molecular Response in Chronic Myelogenous Leukemia
Condition: Chronic Myeloid Leukemia
Intervention: Drug: BL-8040
8 Completed A Trial to Establish the Feasibility of Combining Either the Tyrosine Kinase Inhibitor AC220,CXCR4 Inhibitor Plerixafor or HSP90 Inhibitor Ganetespib With Chemotherapy in Older Patients With Acute Myeloid Leukaemia and High Risk Myelodysplastic Syndrome.
Conditions: Acute Myeloid Leukaemia;   High Risk Myelodysplastic Syndrome
Interventions: Drug: Plerixafor;   Drug: AC220;   Drug: Ganetespib
9 Recruiting Chemo Sensitization Before Hematopoietic Stem Cell Transplantation in Patients With Acute Leukemia in Complete Remission
Conditions: Acute Myeloid Leukemia;   Acute Lymphoid Leukemia
Interventions: Drug: Busulfan;   Drug: Cyclophosphamide;   Drug: CXCR4 Antagonist;   Procedure: Hematopoietic Stem Cell Transplantation
10 Completed First in Human Study to Determine the Safety, Tolerability and Preliminary Efficacy of an Anti-CXCR4 Antibody in Subjects With Acute Myelogenous Leukemia and Selected B-cell Cancers
Conditions: Acute Myelogenous Leukemia;   Diffuse Large B-Cell Leukemia;   Chronic Lymphocytic Leukemia;   Follicular Lymphoma
Intervention: Drug: BMS-936564 (Anti-CXCR4)
11 Unknown  The Role of SDF-1/CXCR4 in Metastasis of Oral Squamous Cell Carcinoma
Condition: Oral Cancer
Intervention:
12 Completed Auto-immunity in Lupus Patients After Influenza Vaccine
Condition: Systemic Lupus Erythematosus (SLE)
Intervention: Drug: Vaccine
13 Unknown  The Role of Stromal Cell-Derived Factor-1 (SDF-1)/CXC Chemokine Receptor 4 (CXCR4) in Metastasis of Laryngeal and Hypopharyngeal Squamous Cell Carcinoma
Conditions: Laryngeal Cancer;   Hypopharyngeal Cancer;   Metastasis
Intervention:
14 Terminated First in Man Study of ALX-0651, a Nanobody Inhibiting CXCR4
Condition: Healthy Volunteers
Interventions: Biological: ALX-0651;   Biological: Placebo
15 Completed
Has Results
AMD 3100 for Treatment of Myelokathexis
Condition: Neutropenia
Intervention: Drug: AMD3100 or plerixafor
16 Unknown  Studies on the Significance of CXCR4-CXCL12 on Leukemic Cells Passing Through"Marrow-Blood Barrier"
Conditions: Acute Myelocytic Leukemia;   Acute Lymphocytic Leukemia
Intervention:
17 Recruiting A Study of LY2510924 and Durvalumab in Participants With Solid Tumors
Condition: Solid Tumor
Interventions: Drug: LY2510924;   Drug: Durvalumab
18 Unknown  Prognostic Potential of Cell Surface Markers and Pim Kinases in Multiple Myeloma
Condition: Multiple Myeloma
Intervention:
19 Completed Safety and Activity of the Oral HIV Entry Inhibitor AMD11070 in HIV Infected Patients
Condition: HIV Infections
Intervention: Drug: AMD11070
20 Recruiting Plerixafor Versus G-CSF in the Treatment of People With WHIM Syndrome
Conditions: Myelokathexis;   WHIMS;   Neutropenia;   Warts
Interventions: Drug: Plerixafor;   Drug: G-CSF

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Study has passed its completion date and status has not been verified in more than two years.