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59 studies found for:    CML | Canada
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Rank Status Study
1 Recruiting Allogeneic SCT for CML, TKI Failure After TKI Failure
Condition: Chronic Myeloid Leukemia
Intervention:
2 Terminated Chromosome Abnormalities in Chronic Myeloid Leukemia (CML) on Imatinib. GIST Patients on Imatinib
Conditions: Chronic Myeloid Leukemia;   Gastrointestinal Stromal Cell Tumors;   Chromosome Abnormality
Intervention: Procedure: bone marrow aspiration
3 Completed Study Comparing Standard Dose and High-dose Imatinib Mesylate in Patients With Chronic Phase Philadelphia Chromosome Positive (Ph+) Chronic Myelogenous Leukemia (CML)
Condition: Chronic Myelogenous Leukemia
Intervention: Drug: imatinib mesylate
4 Unknown  A Study Investigating the Predictive Value of Philadelphia Positive Stem Cell Properties in Newly Diagnosed Patients With Chronic Myeloid Leukemia in Chronic Phase Receiving Treatment With Imatinib
Condition: Chronic Myeloid Leukemia
Intervention: Procedure: Stem Cell and Mutational Assay
5 Recruiting Phase I/II Study of Nilotinib/Ruxolitinb Therapy for TKI Resistant Ph-Leukemia
Conditions: Chronic Phase Chronic Myeloid Leukemia;   Accelerated Phase Chronic Myeloid Leukemia;   Blastic Phase Chronic Myeloid Leukemia;   Philadelphia Positive Acute Lymphoblastic Leukemia;   Resistant to Tyrosine Kinase Inhibitor Therapy
Interventions: Drug: Nilotinib;   Drug: Ruxolitinib
6 Completed Safety and Efficacy of Obatoclax Mesylate (GX15-070MS) for the Treatment of Hematological Malignancies
Condition: Hematological Malignancies
Intervention: Drug: Obatoclax mesylate (GX15-070MS)
7 Terminated Proof of Concept Trial of Gleevec (Imatinib) in Active Diffuse Scleroderma
Condition: Scleroderma
Interventions: Drug: Imatinib mesylate;   Other: Placebo
8 Completed Investigating Intracellular and Plasma Imatinib Levels in Chronic Myeloid Leukemia
Condition: Chronic Myeloid Leukemia
Intervention:
9 Completed A Study of Oral AMN107 in Adults With Chronic Myelogenous Leukemia (CML) or Other Blood Related Cancers
Conditions: Chronic Myelogenous Leukemia;   Acute Lymphoblastic Leukemia (Philadelphia Chromosome Positive);   Hypereosinophilic Syndrome;   Systemic Mastocytosis
Intervention: Drug: Nilotinib
10 Active, not recruiting A Phase II Study of Dasatinib in Children and Adolescents With Newly Diagnosed Chronic Phase CML or With Ph+ Leukemias Resistant or Intolerant to Imatinib
Condition: Leukemia
Intervention: Drug: Dasatinib
11 Recruiting Treatment-free Remission Accomplished With Dasatinib in Patients With CML
Condition: Chronic Myeloid Leukemia
Intervention: Drug: Dasatinib
12 Active, not recruiting Ponatinib for Chronic Myeloid Leukemia (CML) Evaluation and Ph+ Acute Lymphoblastic Leukemia (ALL)
Conditions: Chronic Myeloid Leukemia;   Ph+ Acute Lymphoblastic Leukemia
Intervention: Drug: Ponatinib
13 Recruiting Bosutinib Treatment Extension Study Only For Subjects With Chronic Myeloid Leukemia (CML) Who Have Previously Participated In Bosutinib Studies B1871006 Or B1871008
Condition: Chronic Myeloid Leukemia
Intervention: Drug: bosutinib
14 Active, not recruiting
Has Results
A Study of Imatinib Versus Nilotinib in Adult Patients With Newly Diagnosed Philadelphia Chromosome Positive (Ph+) Chronic Myelogenous Leukemia in Chronic Phase (CML-CP)
Condition: Myelogenous Leukemia, Chronic
Interventions: Drug: nilotinib;   Drug: imatinib
15 Completed
Has Results
Dasatinib Combination Therapy With the Smoothened (SMO) Inhibitor BMS-833923 in Chronic Myeloid Leukemia (CML)
Condition: Leukemia
Interventions: Drug: Dasatinib;   Drug: BMS-833923
16 Completed
Has Results
Homoharringtonine (Omacetaxine Mepesuccinate) in Treating Patients With Chronic Myeloid Leukemia (CML) With the T315I BCR-ABL Gene Mutation
Condition: Chronic Myeloid Leukemia
Intervention: Drug: Omacetaxine mepesuccinate
17 Completed
Has Results
Open Label Study of Subcutaneous Homoharringtonine (Omacetaxine Mepesuccinate) in Patients With Advanced CML
Condition: Chronic Myeloid Leukemia
Intervention: Drug: Omacetaxine mepesuccinate
18 Active, not recruiting Treatment-free Remission After Achieving Sustained MR4.5 on Nilotinib (ENESTop)
Condition: Chronic Myeloid Leukemia
Intervention: Drug: nilotinib
19 Completed
Has Results
Compare Bosutinib To Imatinib In Subjects With Newly Diagnosed Chronic Phase Philadelphia Chromosome Positive CML
Condition: Chronic Myeloid Leukemia
Interventions: Drug: Bosutinib;   Drug: imatinib
20 No longer available Oral Nilotinib in Adults With Chronic Myeloid Leukemia (CML) in Blast Crisis Who Are Imatinib Resistant or Intolerant
Condition: Chronic Myelogenous Leukemia
Intervention: Drug: nilotinib

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Study has passed its completion date and status has not been verified in more than two years.