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25 studies found for:    CASR
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Rank Status Study
1 Unknown  Regulation of Vitamin D Receptor (VDR),Calcium Sensing Receptor (CaSR), Cyclin D1,Ki67 and Proliferating Cell Nuclear Antigen (PCNA) in Primary Hyperparathyroidism
Condition: Primary Hyperparathyroidism (PHPT)
2 Completed Study of the Influence of the Expression of the Calcium-sensitive Receptor (CaSR) by Monocytes in the Synovial Liquid on Structural Alterations in Patients Diagnosed With Rheumatoid Arthritis in the Previous Two Years
Condition: Arthritis, Rheumatoid
Intervention: Biological: blood
3 Completed The Expression of Matrix Metalloproteinase 13, Tissue Inhibitor of Metalloproteinases 3, and Calcium-sensing Receptor in Human Trabecular Meshwork
Condition: Open-angle Glaucoma
Intervention: Procedure: trabeculectomy
4 Recruiting Lipid and Glycogen Metabolism in Patients With Impaired Glucose Tolerance and Calcium Sensing Receptor Mutations
Conditions: Type 2 Diabetes Mellitus;   Prediabetes (Insulin Resistance, Impaired Glucose Tolerance);   Familiar Hypocalcuric Hypercalcemia;   Healthy Volunteers;   Type 1 Diabetes Mellitus
Interventions: Device: 1H/ 13C and 31P Magnetic Resonance Spectroscopy;   Other: Meal Tolerance Test;   Other: Hyperglycemic-hyperinsulinemic clamp
5 Completed The Study of Efficacy and Safety of REGPARA Drug in Dialysis Patients Have High Blood Levels of Parathyroid
Condition: Hyperparathyroidism, Secondary
Intervention: Drug: calcium sensing receptor agonist
6 Completed
Has Results
A Study to Determine the Effects of NPSP795 on the Calcium-sensing Receptor in Subjects With Autosomal Dominant Hypocalcemia as Measured by PTH Levels and Blood Calcium Concentrations
Condition: Autosomal Dominant Hypocalcemia (ADH)
Intervention: Drug: NPSP795
7 Recruiting New Transporting Solution in Parathyroid Allotransplantation
Condition: Parathyroid Allotransplantation
Intervention: Drug: BAVU Solution
8 Completed An Adaptive Phase I Study to Evaluate the Safety, Efficacy and Dose Responses of Ronacaleret in Healthy Human Volunteers
Condition: Bone Marrow Transplantation
Interventions: Drug: Ronacaleret (100mg tablet);   Drug: Placebo
9 Unknown  Parathyroid Hormone (PTH) Homeostasis in Bartter Syndrome
Conditions: Hypocalcemia;   Hypercalcemia
10 Recruiting University of Wisconsin Solution Versus New Parathyroid Transport Solution for Parathyroid Allotransplantation
Condition: Parathyroid Allotransplantation
Intervention: Combination Product: NPT and UW Solution
11 Recruiting Recombinant Human rhPTH(1-34) VS Association Alfacalcidol/Hydrochlorothiazide in Autosomal Dominant Hypocalcemia
Condition: Autosomal Dominant Hypocalcemia
Interventions: Drug: Teriparatide;   Drug: Thiazide;   Drug: Potassium sparing diuretic;   Drug: Alfacalcidol
12 Completed Study in Healthy Volunteers, to Evaluate the Safety, Efficacy and Dose Responses of SB-751689 (Ronacaleret)
Condition: Transplantation, Stem Cell
Interventions: Drug: Ronacaleret 100 mg;   Drug: Ronacaleret 400 mg;   Drug: Plerixafor
13 Completed A Study To Investigate The Metabolism And Excretion Of 14C SB-751689 Given To Healthy Males And Postmenopausal Women
Condition: Osteoporosis
Intervention: Drug: SB-751689
14 Completed A Study to Estimate the Effect of Formulation on the Relative Absorption of SB-751689 Administered to Healthy Women
Condition: Osteoporosis
Intervention: Drug: SB-751689 oral tablets (400 mg)
15 Completed To Estimate Relative Bioavailability of 5 Formulations of Ronacaleret Given to Healthy Postmenopausal Females
Condition: Osteoporosis
Intervention: Drug: Ronacaleret
16 Completed The Effects of Peroxisome Proliferators Activated Receptor-Gamma (PPAR-γ) Agonists on Certain Biochemical and Inflammatory Markers in Metabolic Syndrome
Condition: Metabolic Syndrome
Interventions: Drug: Pioglitazone;   Drug: Telmisartan
17 Completed The Effect of Cinacalcet on Gastric Acid Output in Healthy Subjects
Condition: Healthy
Intervention: Drug: cinacalcet
18 Not yet recruiting Treatment of Primary Hyperparathyroidism With Denosumab and Cinacalcet.
Conditions: Primary Hyperparathyroidism;   Parathyroid Adenoma;   Parathyroid Hyperplasia
Interventions: Drug: Cinacalcet 30 mg Tablet;   Drug: Denosumab Inj 60 mg/ml;   Other: Placebo tablets;   Other: Saline Injection (Placebo)
19 Completed Study of the Effect of Alendronate on Vascular Calcification and Arterial Stiffness in Chronic Kidney Disease
Conditions: Vascular Calcification;   Arteriosclerosis
Interventions: Drug: Alendronate;   Drug: Placebo
20 Completed CR9112792, a Follow-up of Study CR9108963
Condition: Osteoporosis
Intervention: Procedure: DXA

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Study has passed its completion date and status has not been verified in more than two years.