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157 studies found for:    Brain and Spinal Tumors
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Rank Status Study
21 Active, not recruiting Dose Escalation/De-escalation Study of Pre-operative Stereotactic Radiosurgery for Brain Metastases(RAD 1002)
Condition: Brain Metastases
Intervention: Radiation: Stereotactic Radiosurgery
22 Completed DepoCyt Therapy in Patients With Neoplastic Meningitis From Lymphoma or a Solid Tumor
Condition: Meningeal Neoplasms
Interventions: Drug: Intrathecal (injected into the spinal fluid) DepoCyt;   Drug: Intrathecal methotrexate;   Drug: Intrathecal cytarabine (also known as ara-C)
23 Enrolling by invitation Eligibility Screening for a NCI Pediatric Oncology Branch Research Study
Conditions: Ewing Sarcoma;   Osteosarcoma;   Neuroblastoma;   Acute Lymphoblastic Leukemia;   Neurofibromatosis Type 1
Intervention:
24 Recruiting A Trial of Poly-ICLC in the Management of Recurrent Pediatric Low Grade Gliomas
Condition: Brain Tumors
Intervention: Drug: Poly ICLC
25 Terminated Intrathecal Gemcitabine to Treat Neoplastic Meningitis, IT Gemcitabine
Conditions: Meningitis;   Neoplasms
Intervention: Drug: Gemcitabine
26 Active, not recruiting Radiation Therapy, Temozolomide, and Lomustine in Treating Young Patients With Newly Diagnosed Gliomas
Conditions: Brain Tumors;   Central Nervous System Tumors
Interventions: Drug: lomustine;   Drug: temozolomide;   Procedure: adjuvant therapy;   Radiation: radiation therapy
27 Completed
Has Results
Erlotinib and Radiation Therapy in Treating Young Patients With Newly Diagnosed Glioma
Condition: Brain and Central Nervous System Tumors
Intervention: Drug: Erlotinib hydrochloride
28 Completed Collection of Tumor Tissue, Blood and Spinal Fluid From Patients With Brain or Spine Tumors
Condition: Primary or Metastatic Central Nervous System (CNS) Tumor
Intervention:
29 Active, not recruiting
Has Results
Bevacizumab and Irinotecan in Treating Young Patients With Recurrent, Progressive, or Refractory Glioma, Medulloblastoma, Ependymoma, or Low Grade Glioma
Conditions: Childhood Cerebral Anaplastic Astrocytoma;   Childhood Oligodendroglioma;   Childhood Spinal Cord Neoplasm;   Recurrent Childhood Brain Stem Glioma;   Recurrent Childhood Ependymoma;   Recurrent Childhood Medulloblastoma
Interventions: Biological: Bevacizumab;   Radiation: Fludeoxyglucose F-18;   Drug: Irinotecan Hydrochloride
30 Terminated (11C)dLop as a Marker of P-Glycoprotein Function in Patients With Gliomas
Conditions: Low Grade Glioma;   Glioblastoma Multiforme;   Anaplastic Astrocytoma;   Anaplastic Oligodendroglioma;   Oligoastrocytoma
Intervention:
31 Recruiting A Phase I Study of Mebendazole for the Treatment of Pediatric Gliomas
Conditions: Pilomyxoid Astrocytoma;   Pilocytic Astrocytoma;   Glioma, Astrocytic;   Optic Nerve Glioma;   Pleomorphic Xanthoastrocytoma;   Glioblastoma Multiforme;   Anaplastic Astrocytoma;   Gliosarcoma;   Diffuse Intrinsic Pontine Glioma;   DIPG;   Low-grade Glioma;   Brainstem Glioma
Interventions: Drug: Mebendazole;   Drug: Vincristine;   Drug: Carboplatin;   Drug: Temozolomide;   Drug: Bevacizumab;   Drug: Irinotecan
32 Completed Combination Antibody Therapy for Relapsed Lymphoma and Chronic Lymphocytic Leukemia
Conditions: Diffuse Large B-Cell Lymphoma;   Follicular Lymphoma;   Chronic Lymphocytic Leukemia;   Mantle Cell Lymphoma;   Small Lymphocytic Lymphoma
Interventions: Biological: Apolizumab;   Biological: Rituximab
33 Completed Phase 1 Intrathecal Topotecan for Neoplastic Meningitis
Condition: Neoplastic Meningitis
Intervention: Drug: Topotecan
34 Completed Chemotherapy and Radiation Therapy After Surgery in Treating Children With Newly Diagnosed Astrocytoma, Glioblastoma Multiforme, Gliosarcoma, or Diffuse Intrinsic Pontine Glioma
Condition: Brain and Central Nervous System Tumors
Interventions: Drug: temozolomide;   Procedure: adjuvant therapy;   Radiation: radiation therapy
35 Not yet recruiting Pembrolizumab In Central Nervous System Metastases
Condition: Brain Metastases
Interventions: Drug: Pembrolizumab;   Radiation: MRI;   Radiation: PET/CT;   Procedure: Stereotactic Radiosurgery
36 Unknown  Combination Chemotherapy and Radiation Therapy With or Without Methotrexate in Treating Young Patients With Newly Diagnosed Gliomas
Condition: Brain and Central Nervous System Tumors
Interventions: Drug: cisplatin;   Drug: etoposide;   Drug: ifosfamide;   Drug: lomustine;   Drug: methotrexate;   Drug: prednisone;   Drug: vincristine sulfate
37 Completed SCH 66336 in Treating Children With Recurrent or Progressive Brain Tumors
Condition: Brain and Central Nervous System Tumors
Intervention: Drug: lonafarnib
38 Completed ABT-888 and Temozolomide in Treating Young Patients With Recurrent or Refractory CNS Tumors
Conditions: Childhood Atypical Teratoid/Rhabdoid Tumor;   Childhood Central Nervous System Germ Cell Tumor;   Childhood Choroid Plexus Tumor;   Childhood Craniopharyngioma;   Childhood Ependymoblastoma;   Childhood Grade I Meningioma;   Childhood Grade II Meningioma;   Childhood Grade III Meningioma;   Childhood High-grade Cerebellar Astrocytoma;   Childhood High-grade Cerebral Astrocytoma;   Childhood Infratentorial Ependymoma;   Childhood Low-grade Cerebellar Astrocytoma;   Childhood Low-grade Cerebral Astrocytoma;   Childhood Medulloepithelioma;   Childhood Mixed Glioma;   Childhood Oligodendroglioma;   Childhood Supratentorial Ependymoma;   Recurrent Childhood Brain Stem Glioma;   Recurrent Childhood Brain Tumor;   Recurrent Childhood Cerebellar Astrocytoma;   Recurrent Childhood Cerebral Astrocytoma;   Recurrent Childhood Ependymoma;   Recurrent Childhood Medulloblastoma;   Recurrent Childhood Pineoblastoma;   Recurrent Childhood Spinal Cord Neoplasm;   Recurrent Childhood Subependymal Giant Cell Astrocytoma;   Recurrent Childhood Supratentorial Primitive Neuroectodermal Tumor;   Recurrent Childhood Visual Pathway and Hypothalamic Glioma
Interventions: Drug: veliparib;   Drug: temozolomide;   Other: pharmacological study;   Other: laboratory biomarker analysis
39 Active, not recruiting
Has Results
Donepezil in Treating Young Patients With Primary Brain Tumors Previously Treated With Radiation Therapy to the Brain
Conditions: Brain and Central Nervous System Tumors;   Cognitive/Functional Effects;   Long-term Effects Secondary to Cancer Therapy in Children;   Neurotoxicity;   Psychosocial Effects of Cancer and Its Treatment;   Radiation Toxicity
Intervention: Drug: Donepezil
40 Completed Study of Systemic and Spinal Chemotherapy Followed by Radiation for Infants With Brain Tumors
Condition: Brain Tumors
Interventions: Drug: Induction therapy (Regimen 1, Course 1, Cycle A1;   Drug: Regimen 1, Course 1, Cycle A2 (Days 22 - 42);   Drug: Cycle B;   Drug: Regimen 1, Course 2;   Drug: Intrathecal Mafosfamide;   Drug: Regimen 1 Course 2, IT mafosfamide;   Drug: Regimen 2, Course 1;   Drug: Regimen 2, Course, 1, Cycle C1;   Drug: Regimen 2, Course 2;   Radiation: radiation therapy

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Study has passed its completion date and status has not been verified in more than two years.