1164 studies found for:    BCR
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Rank Status Study
1 Recruiting Phase II Front-line Ponatinib in Adult Philadelphia+/BCR-ABL+ Acute Lymphoblastic Leukemia.
Conditions: Philadelphia Positive;   BCR-ABL Positive;   Acute Lymphoblastic Leukemia
Intervention: Drug: Ponatinib
2 Recruiting Front-line Nilotinib Treatment of BCR-ABL+ Chronic Myeloid Leukaemia in Chronic Phase
Conditions: Chronic Phase Philadelphia Positive;   BCR-ABL Positive;   Chronic Myeloid Leukaemia
Intervention:
3 Terminated Pharmacokinetic Profile of Vincristine Administered With Imatinib for Bcr-Abl Positive Acute Lymphoblastic Leukemia (ALL) Compared to That Without Imatinib for Bcr-Abl Negative ALL
Condition: Acute Lymphoblastic Leukemia
Intervention:
4 Completed Nilotinib in Newly Diagnosed Adult Philadelphia Chromosome and /or BCR-ABL Positive Chronic Myeloid Leukaemia in Chronic Phase
Condition: Leukemia, Myeloid
Intervention: Drug: Nilotinib
5 Active, not recruiting Philadelphia Chromosome Positive CML Patients Without Optimal Response or Tolerance to Bcr-Abl TKI
Conditions: Leukemia;   Leukemia, Myeloid;   Leukemia, Myelogenous, Chronic, BCR-ABL Positive;   Philadelphia Chromosome;   Hematologic Diseases
Intervention: Drug: Radotinib
6 Active, not recruiting Nilotinib in PH+, BCR-, ABL+ CML Patients
Condition: Chronic Myeloid Leukemia
Intervention: Drug: Nilotinib
7 Recruiting Nilotinib-Chemotherapy in CML Myeloid BP or Bcr-abl(+) AML
Conditions: Chronic Myeloid Leukemia in Myeloid Blast Crisis;   Untreated Adult Acute Myeloid Leukemia
Intervention: Drug: Nilotinib+AD induction
8 Recruiting Treatment of Acute Lymphoblastic Leukemia Ph '(BCR / ABL) Positive Patients Aged > 55 Years
Condition: Acute Lymphoblastic Leukemia Ph Positive
Interventions: Drug: Dexamethasone;   Drug: Methotrexate;   Drug: Vincristine
9 Completed Study of Imatinib-Combined Chemotherapy for BCR-ABL-Positive Acute Lymphoblastic Leukemia (ALL)
Condition: Acute Lymphoblastic Leukemia
Interventions: Drug: imatinib;   Drug: cyclophosphamide;   Drug: daunorubicin;   Drug: vincristine;   Drug: prednisolone;   Drug: methotrexate;   Drug: cytarabine;   Drug: dexamethasone
10 Completed Safety Assessment of a Multipeptide-gene Vaccine in CML
Condition: Leukemia, Myeloid, Chronic
Interventions: Biological: Bcr-abl multipeptide vaccine;   Genetic: Cytokine gene adjuvant
11 Active, not recruiting Hyper-CVAD Plus Dasatinib in Philadelphia/BCR-ABL Positive ALL
Conditions: Acute Lymphoblastic Leukemia;   Leukemia
Interventions: Drug: Cyclophosphamide;   Drug: Vincristine;   Drug: Doxorubicin;   Drug: Dexamethasone;   Drug: Dasatinib;   Drug: Methotrexate;   Drug: Ara-C
12 Active, not recruiting Hyper-CVAD and Ponatinib in Ph-Positive and/or BCR-ABL Positive Acute Lymphoblastic Leukemia (ALL)
Condition: Leukemia
Interventions: Drug: Cyclophosphamide;   Drug: Mesna;   Drug: Doxorubicin;   Drug: Vincristine;   Drug: Dexamethasone;   Drug: Ponatinib;   Drug: G-CSF (Filgrastim);   Drug: Rituximab;   Drug: Methotrexate;   Drug: Cytarabine;   Drug: Solu-medrol ( Methyl Prednisolone);   Drug: Citrovorum (Leucovorin);   Drug: Prednisone;   Drug: Pegfilgrastim (Neulasta)
13 Unknown  TKI Therapy Based on Molecular Monitoring in Allogeneic-HSCT Recipients With Philadelphia Chromosome-positive Acute Lymphoblastic Leukemia
Conditions: Philadelphia Chromosome Positive Acute Lymphocytic Leukemia;   Stem Cell Transplantation;   Minimal Residual Disease
Intervention: Drug: TKI
14 Completed
Has Results
Homoharringtonine (Omacetaxine Mepesuccinate) in Treating Patients With Chronic Myeloid Leukemia (CML) With the T315I BCR-ABL Gene Mutation
Condition: Chronic Myeloid Leukemia
Intervention: Drug: Omacetaxine mepesuccinate
15 Not yet recruiting ACY-1215 in Combination With BCR Pathway Inhibitors in Relapsed CLL
Condition: Recurrent Chronic Lymphoid Leukemia
Interventions: Drug: ACY-1215;   Drug: Ibrutinib;   Drug: Idelalisib
16 Recruiting Front-line Treatment of BCR-ABL+ Chronic Myeloid Leukemia (CML) With Dasatinib
Condition: Chronic Myeloid Leukemia
Intervention: Behavioral: Dasatinib discontinuation
17 Recruiting Transvaginal Treatment of Symptomatic Cystocele Grade II-III
Condition: Cystocele
Intervention: Device: cystocele repair with biomesh soft prolaps and endofast reliant
18 Terminated
Has Results
Vaccine Therapy in Treating Patients With Chronic Phase Chronic Myelogenous Leukemia
Condition: Leukemia
Interventions: Biological: bcr-abl peptide vaccine;   Genetic: reverse transcriptase-polymerase chain reaction
19 Completed A Study of Gleevec in Patients With Idiopathic Myelofibrosis or Chronic Myelomonocytic Leukemia (CMML)
Conditions: Myelofibrosis;   Myeloid Metaplasia;   Agnogenic Myeloid Metaplasia;   Chronic Myelomonocytic Leukemia
Intervention: Drug: Imatinib mesylate
20 Recruiting Combination Chemotherapy With or Without Blinatumomab in Treating Patients With Newly Diagnosed BCR-ABL-Negative B Lineage Acute Lymphoblastic Leukemia
Conditions: Adult B Acute Lymphoblastic Leukemia;   Untreated Adult Acute Lymphoblastic Leukemia
Interventions: Procedure: Allogeneic Hematopoietic Stem Cell Transplantation;   Biological: Blinatumomab;   Drug: Cyclophosphamide;   Drug: Cytarabine;   Drug: Daunorubicin Hydrochloride;   Drug: Dexamethasone;   Drug: Etoposide;   Other: Laboratory Biomarker Analysis;   Drug: Mercaptopurine;   Drug: Methotrexate;   Drug: Pegaspargase;   Drug: Prednisone;   Drug: Vincristine Sulfate

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Indicates status has not been verified in more than two years