| 101 |
NCT02627131 |
Completed |
Autologous Bone Marrow Stem Cell Therapy for Autism |
|
- Biological: Autologous Bone Marrow Mononuclear Cells
|
Interventional
|
Phase 2 |
|
Other |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Change in Total Score of Childhood Autism Rating Scale (CARS)
- Number of adverse events
|
24 |
All |
3 Years to 16 Years (Child) |
NCT02627131 |
TBG 003 |
|
April 2014 |
December 2015 |
December 2015 |
December 10, 2015 |
December 10, 2015 |
|
- Vinmec International Hospital
Hanoi, Vietnam
|
|
| 102 |
NCT01248728 |
Completed
Has Results |
Omega-3 Fatty Acids For Treatment Of Young Children With Autism (OMG) |
|
- Dietary Supplement: Omega-3 Fatty Acids
- Dietary Supplement: Placebo
|
Interventional
|
Phase 2 |
- Evdokia Anagnostou
- Holland Bloorview Kids Rehabilitation Hospital
- The Hospital for Sick Children
- Anagnostou, Evdokia, M.D.
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Change From Baseline in the Pervasive Developmental Disorder-Behavioral Inventory (PDDBI) - Autism Composite Score
- Change From Baseline in the Behaviour Assessment System for Children (BASC-2) - Externalizing Problems Composite
- Number of Participants Classified as Responders by the Clinical Global Impression - Improvement (CGI-I)
- (and 2 more...)
|
38 |
All |
2 Years to 5 Years (Child) |
NCT01248728 |
09-018 |
|
November 2010 |
December 2013 |
June 2014 |
November 25, 2010 |
May 18, 2016 |
May 18, 2016 |
- Holland Bloorview Kids Rehabilitation Hospital
Toronto, Ontario, Canada
|
|
| 103 |
NCT02940899 |
Recruiting |
Syracuse University Fit Families Program: Autism |
- Autism Spectrum Disorders
|
- Other: Intervention: Syracuse University Fir Families Program (SUFFP)
|
Interventional
|
Not Applicable |
- Syracuse University
- Texas Woman's University
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Supportive Care
|
- Physical Activity
- Motor skills of Parents and Children
- Adaptive behavior
- (and 5 more...)
|
90 |
All |
5 Years to 11 Years (Child) |
NCT02940899 |
28491 |
SUFFP |
January 2015 |
May 2018 |
December 2018 |
October 21, 2016 |
December 2, 2017 |
|
- Syracuse University
Syracuse, New York, United States
|
|
| 104 |
NCT02862340 |
Completed |
Study of the Involvement of 15q11 - q13 Chromosome Region and CYFIP1 Gene in Autism. Attempt a Genotype-phenotype Correlation |
|
|
Interventional
|
Not Applicable |
- Centre Hospitalier Universitaire de Nice
|
Other |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Diagnostic
|
- presence or absence of abnormality in 15q11q13 gene
- phenotype
|
60 |
All |
4 Years to 18 Years (Child, Adult) |
NCT02862340 |
07-PP-01 |
|
January 2008 |
January 2008 |
February 2012 |
August 11, 2016 |
August 11, 2016 |
|
|
|
| 105 |
NCT01614275 |
Active, not recruiting |
Using Web-based Technology to Expand and Enhance Applied Behavioral Analysis Programs for Children With Autism in Military Families |
- Autism Spectrum Disorders
|
- Behavioral: Technology-Enhanced Parent Training
- Behavioral: Technology-Enhanced Tutor Training
- Behavioral: Technology-enhanced Early Intensive Behavioral Intervention
- Behavioral: No-Intervention
|
Interventional
|
Not Applicable |
- University of Nebraska
- State University of New York - Upstate Medical University
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Investigator)
- Primary Purpose: Treatment
|
- Intelligent Quotient: Differential Abilities Scales, Second Edition
- Parent Training: Behavioral Implementation Skills for Play Activities
- Tutor Training: Behavioral Implementation of Work Activities
|
66 |
All |
18 Months to 48 Months (Child) |
NCT01614275 |
059-11
W81XWH-11-1-0444 |
|
May 30, 2012 |
July 1, 2017 |
July 1, 2018 |
June 7, 2012 |
February 7, 2018 |
|
- University of Nebraska Medical Center
Omaha, Nebraska, United States
|
|
| 106 |
NCT01260961 |
Active, not recruiting |
Developing Treatment, Treatment Validation and Treatment Scope in the Setting of an Autism Clinical Trial |
|
- Dietary Supplement: Placebo
- Dietary Supplement: Docosahexanoic Acid
|
Interventional
|
Not Applicable |
- Rutgers, The State University of New Jersey
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Amelioration of phenotypic features of autism
- oxidative stress biomarkers
|
132 |
All |
5 Years to 17 Years (Child) |
NCT01260961 |
0220080189 |
|
November 2010 |
November 2013 |
December 2017 |
December 15, 2010 |
November 29, 2016 |
|
- Rutgers
Piscataway, New Jersey, United States
|
|
| 107 |
NCT00819364 |
Unknown † |
Early Intervention Program for Children With Autism (BCRI Model) |
- Autism
- Autism Spectrum Disorder
|
- Behavioral: BCRI intervention program
- Behavioral: Standard community care
|
Interventional
|
Not Applicable |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Treatment
|
- Psychoeducational Profile-3rd Edition(PEP-3)
- SRS(social response scale) scores and/or C-WYCSI scores at 2-year follow-up. SRS(social response scale) scores and/or C-WYSC scores at 5-year follow-up.
|
200 |
All |
up to 30 Months (Child) |
NCT00819364 |
2007024 |
|
August 2009 |
August 2013 |
August 2016 |
January 9, 2009 |
August 11, 2009 |
|
|
|
| 108 |
NCT03538431 |
Not yet recruiting
New |
Improving Driving in Young People With Autism Spectrum Disorders |
|
|
Interventional
|
Phase 4 |
- Massachusetts General Hospital
- Massachusetts Institute of Technology
|
Other |
- Allocation: Randomized
- Intervention Model: Crossover Assignment
- Masking: Single (Investigator)
- Primary Purpose: Other
|
|
24 |
All |
18 Years to 24 Years (Adult) |
NCT03538431 |
2018-P-000900 |
|
June 15, 2018 |
June 15, 2020 |
June 15, 2020 |
May 28, 2018 |
May 28, 2018 |
|
- Massachusetts General Hospital
Boston, Massachusetts, United States
|
|
| 109 |
NCT03003221 |
Recruiting |
Improving Dental Care and Oral Health in Children With Autism Spectrum Disorder |
|
- Behavioral: AIR-P Dental Toolkit
- Behavioral: Parent Training
|
Interventional
|
Not Applicable |
- Rachel Fenning
- Massachusetts General Hospital
- Nationwide Children's Hospital
- (and 3 more...)
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Treatment
|
- Frequency of tooth brushing at home
- Child oral health according to standardized measures from visual exam
- Child behavior during tooth brushing at home according to questionnaire
- (and 3 more...)
|
85 |
All |
3 Years to 13 Years (Child) |
NCT03003221 |
2016-3043 |
|
December 2016 |
March 2019 |
September 2019 |
December 26, 2016 |
January 5, 2017 |
|
- University of California Irvine
Irvine, California, United States - Nationwide Children's Hospital
Columbus, Ohio, United States
|
|
| 110 |
NCT01238250 |
Recruiting |
Online Study of Individuals With Genetic Changes and Features of Autism: Simons Variation in Individuals Project (Simons VIP) |
- 16p11.2 Deletions
- 16p11.2 Duplications
- 1q21.1 Deletions
- (and 54 more...)
|
|
Observational
|
|
- Simons VIP Connect
- Geisinger Clinic
- Columbia University
- (and 7 more...)
|
Other |
- Observational Model: Family-Based
- Time Perspective: Prospective
|
- 1. Baseline comprehensive collection of the medical, behavioral, and learning features of individuals with documented genetic changes associated with features of autism and developmental delay
- Longitudinal (long-term) comprehensive collection of the medical, behavioral, and learning features of individuals with documented genetic changes associated with features of autism and developmental delay
|
5000 |
All |
Child, Adult, Older Adult |
NCT01238250 |
2011-0320
Simons VIP Connect |
|
October 2010 |
July 2018 |
July 2018 |
November 10, 2010 |
December 21, 2017 |
|
- Geisinger Health System
Danville, Pennsylvania, United States
|
|
| 111 |
NCT03222375 |
Recruiting |
SQUED™ Series 28.1 Home-use and Treatment of Autowave Reverberator of Autism |
- Autistic Disorder
- Autism Spectrum Disorder
- Child Development Disorders, Pervasive
- (and 5 more...)
|
- Device: SQUED™ series 28.1 home-use
|
Observational
|
|
- American Federation of Medical Synergetics
- Clinic of Synergetics, Department of Neurology/Neuropsychology WOMS
- Institute of Medical Synergetics, Department of Cognitive Neurology WOMS
- (and 7 more...)
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- SQUED™ software of patient
|
80 |
All |
1 Month to 21 Years (Child, Adult) |
NCT03222375 |
SQUED™ series 28.1 home-use |
SQUED™ |
September 26, 2017 |
September 2022 |
December 2027 |
July 19, 2017 |
November 28, 2017 |
|
- World Autism Center, American Federation of Medical Synergetics, Department of Neurology; Cognitive Neurology/Neuropsychology WOMS
Louisville, Kentucky, United States - Clinic of Synergetics, Department of Neurology; Cognitive Neurology/Neuropsychology of the World Organization of Medical Synergetics
Lviv, Solonka Village, Urozayna Street 41, Ukraine
|
|
| 112 |
NCT03294668 |
Not yet recruiting |
KONTAKT Australia a Social Skills Group Training for Adolescents on the Autism Spectrum |
|
- Behavioral: KONTAKT Australia
- Other: Super Chef
|
Interventional
|
Not Applicable |
- Curtin University
- Autism Association of Western Australia
- Karolinska Institutet
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Change in the Goal Attainment Scale (GAS)
- Change in the Social responsiveness scale - Second Edition (SRS-2)
- Change in the Emotion Regulation and Social Skills Questionnaire (ERSSQ)
- (and 7 more...)
|
96 |
All |
12 Years to 17 Years (Child) |
NCT03294668 |
HRE2017-0245 |
|
October 1, 2017 |
February 10, 2018 |
December 25, 2018 |
September 27, 2017 |
September 27, 2017 |
|
|
|
| 113 |
NCT03164746 |
Completed |
Treatment by Therapeutic Body Wraps in Children and Adolescents Suffering From Autism With Severe Injurious Behavior. |
|
- Other: Dry sheet Therapeutic body wraps
- Other: WET sheet Therapeutic body wraps
|
Interventional
|
Not Applicable |
- University Hospital, Lille
- Ministry of Health, France
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Investigator, Outcomes Assessor)
- Primary Purpose: Supportive Care
|
- Aberrant Behavior Checklist (ABC) irritability score
- ABC hyperactivity score
- ABC lethargy score
- (and 6 more...)
|
48 |
All |
5 Years to 18 Years (Child, Adult) |
NCT03164746 |
2007/0715
2007-A01376-47
DGS 2008-0070 |
PACKING |
December 2007 |
December 2014 |
December 2014 |
May 24, 2017 |
May 24, 2017 |
|
- Centre de Santé Mentale Angevin
Angers, France - Centre Hospitalier d'Arras
Arras, France - Centre Hospitalier Robert Ballanger
Aulnay-sous-Bois, France - (and 10 more...)
|
|
| 114 |
NCT02184390 |
Completed |
Parenting Your Young Child With Autism: A Web-Based Tutorial |
|
- Other: On LIne Parent Training Tutorial
|
Interventional
|
Not Applicable |
- Center for Psychological Consultation
- National Institute of Mental Health (NIMH)
|
Other / NIH |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Prevention
|
- System Usability Scale
- Autism Knowledge Test
|
104 |
All |
18 Months to 6 Years (Child) |
NCT02184390 |
5R44MH086936 |
|
May 2013 |
May 2015 |
September 2015 |
July 9, 2014 |
February 3, 2016 |
|
- Center for Psychological Consulation
Madison, Wisconsin, United States
|
|
| 115 |
NCT02627508 |
Recruiting |
Pilot Trial of Pregnenolone in Autism |
- Autism Spectrum Disorder
- Autism
|
- Drug: Pregnenolone
- Drug: Placebo
|
Interventional
|
Phase 2 |
- Stanford University
- Simons Foundation
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Change from baseline in parent rated Aberrant Behavior Checklist Irritability (ABC-I) score during treatment
- Change from baseline in parent rated Aberrant Behavior Checklist (ABC) scores during treatment
- Change from baseline in parent rated Sensory Profile Questionnaire (SPQ) scores during treatment
- (and 9 more...)
|
40 |
All |
14 Years to 25 Years (Child, Adult) |
NCT02627508 |
IRB-34762 |
|
January 29, 2016 |
December 2019 |
December 2019 |
December 11, 2015 |
May 21, 2018 |
|
- Stanford University School of Medicine
Stanford, California, United States
|
|
| 116 |
NCT01333072 |
Completed |
Biomarkers in Autism of Aripiprazole and Risperidone Treatment (BAART) |
|
- Drug: Aripiprazole
- Drug: Risperidone
|
Interventional
|
Phase 4 |
- Medical University of South Carolina
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Supportive Care
|
- To identify phenotypic and genetic traits that predict response to aripiprazole and risperidone in Autistic Disorder
|
82 |
All |
6 Years to 17 Years (Child) |
NCT01333072 |
R01HD062550-01A1 |
BAART |
July 2011 |
August 2015 |
August 2015 |
April 11, 2011 |
March 16, 2016 |
|
- Medical University of South Carolina
Charleston, South Carolina, United States
|
|
| 117 |
NCT01225198 |
Completed |
Vitamin/Mineral Supplement for Children and Adults With Autism |
|
- Dietary Supplement: Multi-Vitamin/Mineral Supplement
- Other: Liquid Placebo
|
Interventional
|
Phase 2 |
- Arizona State University
- Autism Research Institute
- Legacy Foundation
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Oxidative Stress
- Parent Global Impressions - Revised
|
143 |
All |
3 Years to 60 Years (Child, Adult) |
NCT01225198 |
AutismVitaminStudy2008 |
|
May 2008 |
February 2009 |
February 2009 |
October 20, 2010 |
October 20, 2010 |
|
- Arizona State University
Tempe, Arizona, United States
|
|
| 118 |
NCT02007447 |
Suspended |
Oxytocin in Adolescents With Autism Spectrum Disorders |
|
- Drug: OCYTOCINA - SPRAY NASAL
|
Interventional
|
Phase 2
Phase 3 |
- University of Sao Paulo General Hospital
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- SOCIAL SKILLS
- REPETITIVE BEHAVIOR
|
30 |
Male |
12 Years to 18 Years (Child, Adult) |
NCT02007447 |
CAAE 10922213.7.0000.0068 |
OXYASD |
June 2015 |
August 2015 |
May 4, 2018 |
December 10, 2013 |
May 11, 2018 |
|
- Institute os Psychiatry, Clinical Hospital at São Paulo
São Paulo, Brazil
|
|
| 119 |
NCT01493609 |
Completed |
A Clinical Trial of a New Computer Based Intervention for Children With Autism. |
|
- Behavioral: Click-East app
|
Interventional
|
Early Phase 1 |
- University of Edinburgh
- NHS Lothian
- Newcastle University
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Treatment
|
- Autism Diagnostic Observation Schedule - Change (ADOS-C)
|
54 |
All |
15 Months to 6 Years (Child) |
NCT01493609 |
2010/C/PMLD/03
NCF/36343 |
Click-East |
February 2012 |
June 2013 |
June 2013 |
December 16, 2011 |
November 25, 2013 |
|
- University of Edinburgh
Edinburgh, Midlothian, United Kingdom - Clinical Research Facility, Royal Hospital for Sick Children
Edinburgh, Midlothian, United Kingdom
|
|
| 120 |
NCT02472860 |
Completed |
Feasibility and Effectiveness of Computerized Cognitive Training in Adolescents With Autism Spectrum Disorder |
|
- Behavioral: Targeted Cognitive Training (TCT)
- Other: Youth Appropriate Online Games
|
Interventional
|
Not Applicable |
- Massachusetts General Hospital
- Deborah Munroe Noonan Memorial Research Fund
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Cambridge Neuropsychological Test Automated Battery (CANTAB)
|
29 |
All |
13 Years to 17 Years (Child) |
NCT02472860 |
2015P000610 |
MGHTCT |
June 2015 |
August 2, 2017 |
August 2, 2017 |
June 16, 2015 |
March 27, 2018 |
|
|
|
| 121 |
NCT00095420 |
Completed |
Relationship Training for Children With Autism and Their Peers |
|
- Behavioral: Social skills training targeting children with autism
- Behavioral: Social skills training of peers without autism
- Behavioral: Combination treatment of social skills/education about autism
- Behavioral: Usual training
|
Interventional
|
Not Applicable |
- University of California, Los Angeles
- National Institute of Mental Health (NIMH)
|
Other / NIH |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
|
- Social network involvement of autistic children
|
60 |
All |
6 Years to 11 Years (Child) |
NCT00095420 |
U54MH068172
DDTR BD-DD |
|
September 2003 |
June 2008 |
June 2008 |
November 5, 2004 |
May 14, 2013 |
|
- University of California, Los Angeles
Los Angeles, California, United States
|
|
| 122 |
NCT01474993 |
Completed
Has Results |
Sulforaphane-rich Broccoli Sprout Extract for Autism |
|
- Drug: Sulforaphane-rich Broccoli Sprout Extract
- Drug: Placebo
|
Interventional
|
Phase 2 |
- Andrew Zimmerman
- Johns Hopkins University
- University of Massachusetts, Worcester
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Change From Screening/Baseline in Social Responsiveness Scale (SRS) at 4 Weeks, 10 Weeks, 18 Weeks and 22 Weeks
- Change From Screening/Baseline in Aberrant Behavior Checklist (ABC) at 4 Weeks, 10 Weeks, 18 Weeks and 22 Weeks
- Ohio Autism Clinical Global Impression Scale - Severity (OACIS-S) Scale at 4 Weeks, 10 Weeks, 18 Weeks and 22 Weeks
- (and 9 more...)
|
44 |
Male |
13 Years to 30 Years (Child, Adult) |
NCT01474993 |
2011P002221 |
|
December 2011 |
November 2013 |
November 2013 |
November 18, 2011 |
June 6, 2018 |
November 24, 2014 |
- Lurie Center for Autism, MassGeneral Hospital for Children
Lexington, Massachusetts, United States
|
|
| 123 |
NCT03162445 |
Completed |
Bone Mass Accrual in Children With Autism Spectrum Disorder |
- Autism Spectrum Disorder
- Bone Diseases, Developmental
|
|
Observational
|
|
- Massachusetts General Hospital
|
Other |
- Observational Model: Case-Control
- Time Perspective: Cross-Sectional
|
|
49 |
Male |
8 Years to 17 Years (Child) |
NCT03162445 |
2009P002422 |
|
January 11, 2010 |
January 2016 |
January 2016 |
May 22, 2017 |
May 22, 2017 |
|
|
|
| 124 |
NCT02280746 |
Unknown † |
Gluten for Autism Spectrum Disorders |
- Autism Spectrum Disorders
|
|
Interventional
|
Not Applicable |
- Medical University of Warsaw
- Nutricia Foundation
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- The extent of autistic symptoms based on the Autism Diagnostic Observation Schedule - 2 (ADOS-2)
- The severity of symptoms based on a Social Communication Questionnaire (SCQ)
- Presentation of gastrointestinal (GI) functional disorders (evaluation based on a parent-report form - Rome III diagnostic questionnaire
- (and 4 more...)
|
70 |
All |
3 Years to 6 Years (Child) |
NCT02280746 |
RG 8/2013 |
|
September 2014 |
December 2015 |
December 2015 |
October 31, 2014 |
October 31, 2014 |
|
- Medical University of Warsaw
Warsaw, Poland
|
|
| 125 |
NCT02382172 |
Completed |
Social Cognition and Interaction Training for Autism |
|
- Behavioral: Social Cognition and Interaction Training for Autism (SCIT-A)
- Other: Treatment as Usual (TAU)
|
Interventional
|
Not Applicable |
- University of North Carolina, Chapel Hill
- North Carolina Translational and Clinical Sciences Institute
- Carolina Institute for Developmental Disabilities
|
Other |
- Allocation: Non-Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Other
|
- Change in visual attention from baseline as measured by the Tobii Eye Tracking Paradigm
- Change in patient social skills as measured by the Social Responsiveness Scale (SRS)
- Change in patient social cognition as measured by the Hinting Task
- Change in patient social cognition as measured by the Penn Emotion Recognition Task-40 (ER40)
|
44 |
All |
10 Years to 69 Years (Child, Adult, Older Adult) |
NCT02382172 |
14-2804 |
SCIT-A |
January 2015 |
January 2017 |
January 2017 |
March 6, 2015 |
April 25, 2017 |
|
- Carolina Institute for Developmental Disabilities
Carrboro, North Carolina, United States
|
|
| 126 |
NCT01643720 |
Completed |
Emotion Regulation in Preschoolers With Autism and Their Parents |
- Autism Spectrum Disorders
|
|
Observational
|
|
|
Other |
- Observational Model: Case Control
- Time Perspective: Prospective
|
- Emotion regulation(ER)strategies during emotion eliciting episodes
- Salivary hormone levels: Cortisol and Oxytocin of both parent and child
|
80 |
All |
3 Years to 6 Years (Child) |
NCT01643720 |
MMC1013010kCTIL |
|
November 2010 |
May 2011 |
May 2011 |
July 18, 2012 |
April 8, 2015 |
|
- Brill Mental Health Center
Tel Aviv, Israel
|
|
| 127 |
NCT01836562 |
Unknown † |
A Clinical Trial to Study the Safety and Efficacy of Bone Marrow Derived Autologous Cells for the Treatment of Autism |
|
- Biological: STEM CELL THERAPY
|
Interventional
|
Phase 1
Phase 2 |
|
Other |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Improvement in childhood autism rating scale
- Improvement in perfusion of brain with PET scan report
|
100 |
All |
3 Years to 70 Years (Child, Adult, Older Adult) |
NCT01836562 |
00105 |
BMCA |
September 2014 |
June 2016 |
June 2016 |
April 22, 2013 |
September 17, 2014 |
|
- Chaitanya Hospital
Pune, Maharashtra, India
|
|
| 128 |
NCT00498173 |
Completed
Has Results |
Effectiveness of Atomoxetine in Treating ADHD Symptoms in Children and Adolescents With Autism |
|
- Drug: Atomoxetine
- Drug: Placebo
|
Interventional
|
Phase 3 |
- Massachusetts General Hospital
- National Institute of Mental Health (NIMH)
|
Other / NIH |
- Allocation: Randomized
- Intervention Model: Sequential Assignment
- Masking: Triple (Participant, Care Provider, Investigator)
- Primary Purpose: Treatment
|
- ADHD Rating Scale (ADHDRS)-Home Version Total Score (Randomized Phase)
- ADHD Rating Scale (ADHDRS)-Home Version Inattention and Hyperactivity Scores (Randomized Phase)
- Aberrant Behavior Checklist (ABC) (Randomized Phase)
- (and 12 more...)
|
60 |
All |
5 Years to 15 Years (Child) |
NCT00498173 |
R01MH077600
DDTR B2-NDA |
|
July 2007 |
October 2015 |
October 2015 |
July 9, 2007 |
August 14, 2017 |
August 14, 2017 |
- Christian Sarkine Autism Treatment Center at Riley Hospital for Children
Indianapolis, Indiana, United States - Lurie Center - MassGeneral Hospital
Lexington, Massachusetts, United States
|
|
| 129 |
NCT01881750 |
Unknown † |
Pivotal Response Group Treatment for Parents of Young Children With Autism |
|
- Behavioral: Pivotal Response Training
- Behavioral: Parent Education Group
|
Interventional
|
Not Applicable |
- Stanford University
- Autism Speaks
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Change from Baseline in communication during parent-child and clinician-child interactions at 6, 12, and 24 weeks
- Parenting Stress Index
- Family Empowerment Scale
- (and 4 more...)
|
50 |
All |
2 Years to 6 Years (Child) |
NCT01881750 |
SU-11022010-7151 |
|
September 2010 |
September 2013 |
September 2013 |
June 20, 2013 |
June 20, 2013 |
|
- Stanford University School of Medicine
Stanford, California, United States
|
|
| 130 |
NCT02695693 |
Active, not recruiting |
RCT of TeachTown in Autism Support Classrooms: Innovation and Exnovation |
|
- Behavioral: TeachTown
- Behavioral: Discrete Trial Training
- Behavioral: Pivotal Response Training
- Behavioral: Teaching in Functional Routines
|
Interventional
|
Not Applicable |
- University of Pennsylvania
- National Institute of Mental Health (NIMH)
- School District of Philadelphia
|
Other / NIH |
- Allocation: Randomized
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Differential Abilities Scale, 2nd Edition
- Bracken School Readiness Assessment, 3rd Edition
|
212 |
All |
5 Years to 9 Years (Child) |
NCT02695693 |
R01MH106175 |
|
April 2015 |
June 2017 |
March 2019 |
March 1, 2016 |
August 9, 2017 |
|
|
|
| 131 |
NCT03310775 |
Enrolling by invitation |
A Research on the Effect of Korean Version of PEERS Social Skills Training for Young Adults (PEERS-YA-K) With Autism Spectrum Disorder |
- Autism Spectrum Disorder
- Autism
|
- Behavioral: Parent-assisted social skills training program for young adult with ASD
|
Interventional
|
Not Applicable |
- Seoul National University Hospital
|
Other |
- Allocation: Randomized
- Intervention Model: Sequential Assignment
- Masking: Double (Participant, Care Provider)
- Primary Purpose: Treatment
|
- Change from baseline in Autism Diagnostic Observation Schedule(ADOS) at 4 month
- Change from baseline in Test of Adolescent Social Skills Knowledge(TASSK) at 4 month
- Change from baseline in Korean Version of the Social Skills Rating System (K-SSRS) at 4 month
- (and 3 more...)
|
48 |
All |
18 Years to 35 Years (Adult) |
NCT03310775 |
B-1611-371-303 |
|
November 9, 2016 |
October 30, 2018 |
October 30, 2018 |
October 16, 2017 |
October 16, 2017 |
|
|
|
| 132 |
NCT02708069 |
Completed |
e-Unstuck:Interactive e-Learning Software for Parents to Support Executive Functioning and Behavior Regulation in Children With Autism Spectrum Disorder |
|
- Other: e-Unstuck
- Other: Unstuck and On Target
|
Interventional
|
Not Applicable |
- 3-C Institute for Social Development
- Children's National Health System
|
Industry / Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Supportive Care
|
- Change from baseline in parental knowledge of executive function and the Unstuck and On Target (UOT) intervention as measured on the UOT Knowledge Questionnaire.
- Change from baseline in parental stress on the Parenting Stress Index, Fourth Edition, Short Form (PSI-4-SF).
- Change from baseline in parental self-efficacy on the Parenting Sense of Competence Scale.
- Change from baseline in child executive function as measured on the Behavior Rating of Executive Function (BRIEF)
|
97 |
All |
Child, Adult, Older Adult |
NCT02708069 |
1R44MH109193 |
e-Unstuck |
March 1, 2017 |
February 28, 2018 |
February 28, 2018 |
March 15, 2016 |
March 2, 2018 |
|
- Children's National Health System
Rockville, Maryland, United States - 3C Institute
Durham, North Carolina, United States
|
|
| 133 |
NCT02275455 |
Recruiting |
Design Of WELL Being Monitoring Systems, Application in Autism |
|
- Behavioral: real life situations
|
Interventional
|
Not Applicable |
- University Hospital, Clermont-Ferrand
|
Other |
- Allocation: Non-Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Investigator, Outcomes Assessor)
- Primary Purpose: Prevention
|
- Heart Rate Variability from holter electrocardiogram
- Heart Rate Variability from the heart rate transmitter belt
|
60 |
All |
12 Years to 25 Years (Child, Adult) |
NCT02275455 |
CHU-0213
2014-A00611-46 |
Do Well B |
October 2014 |
December 2016 |
December 2018 |
October 27, 2014 |
July 26, 2016 |
|
- University Hospital of Clermont-Ferrand (CHU), France
Clermont-Ferrand, France
|
|
| 134 |
NCT02998684 |
Completed |
Learning Enhancement Through Neurostimulation in Autism |
|
- Device: Active Transcranial Direct Current Stimulation
- Device: Sham Transcranial Direct Current Stimulation
- Behavioral: PEERS Social Skills Training
|
Interventional
|
Not Applicable |
- Medical University of South Carolina
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
|
Other / NIH |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Triple (Participant, Care Provider, Investigator)
- Primary Purpose: Treatment
|
- Test of Adolescent Social Skills Knowledge (TASSK)
- Social Responsiveness Scale (SRS)
- Percent signal change in regions of interest
|
25 |
All |
14 Years to 17 Years (Child) |
NCT02998684 |
Pro00056912 |
LENS |
July 2016 |
July 2017 |
July 2017 |
December 20, 2016 |
May 3, 2018 |
|
- Medical Univeristy of South Carolina
Charleston, South Carolina, United States
|
|
| 135 |
NCT02646696 |
Completed |
Reliability Study Using Electrodermal Activity to Measure Sensory Processing in Children With and Without Autism Spectrum Disorder |
|
- Other: Sensory Challenge Protocol
|
Observational
|
|
- Barpak Geriatric Health Services, Inc. d/b/a Barpak Occupational Therapy
|
Other |
- Observational Model: Case Control
- Time Perspective: Prospective
|
- Electrodermal Activity in response to sensation
|
32 |
Male |
4 Years to 11 Years (Child) |
NCT02646696 |
Barpak-01-EDA |
|
January 2013 |
April 2014 |
May 2014 |
January 6, 2016 |
January 6, 2016 |
|
|
|
| 136 |
NCT01813318 |
Recruiting |
Study of Acamprosate in Autism |
|
- Drug: Acamprosate
- Drug: Placebo
|
Interventional
|
Phase 2
Phase 3 |
- Children's Hospital Medical Center, Cincinnati
- Autism Speaks
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Change from baseline to week 10 on the Social WIthdrawal subscale of ABC
- Change Clinical Global Impression- Improvement
- Change in ABC subscales: Irritability, Stereotypy, Hyperactivity, and Inappropriate Speech from baseline to week 10
|
36 |
All |
5 Years to 17 Years (Child) |
NCT01813318 |
CIN001-Acamprosate in Autism |
|
April 2013 |
February 2018 |
February 2018 |
March 18, 2013 |
July 21, 2017 |
|
- Cincinnati Children's Hospital Medical Center
Cincinnati, Ohio, United States
|
|
| 137 |
NCT02037022 |
Completed |
Pivotal Response Treatment Package for Young Children With Autism |
- Autism Spectrum Disorder (ASD)
- Autism
|
- Behavioral: Pivotal Response Treatment Package (PRT-P)
|
Interventional
|
Not Applicable |
- Stanford University
- National Institute on Deafness and Other Communication Disorders (NIDCD)
|
Other / NIH |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Change from Baseline in communication during parent-child and clinician-child interactions at 6, 12, and 24 weeks
- Change from Baseline on the Preschool Language Scale, 5th Edition (PLS-5) at 12, and 24 weeks
- Change from Baseline on the Sensory Profile Questionnaire at 6, 12, and 24 weeks
- (and 8 more...)
|
48 |
All |
2 Years to 5 Years (Child) |
NCT02037022 |
IRB-28314
R21DC013689 |
PRT-P |
November 2013 |
July 28, 2017 |
July 28, 2017 |
January 15, 2014 |
January 26, 2018 |
|
- Stanford University School of Medicine
Stanford, California, United States
|
|
| 138 |
NCT02874690 |
Recruiting |
Stimulant Autism Test |
- Autism Spectrum Disorder
- Attention Deficit Hyperactivity Disorder
|
- Drug: Methylphenidate
- Drug: Placebo
|
Interventional
|
Phase 2 |
- Children's Hospital Medical Center, Cincinnati
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Change in Eye-Tracking: Microsaccades and pupil size using Tobii eye tracker
- Change in Short Interval IntraCortical Inhibition (SICI) using Transcranial Magnetic Stimulation (TMS)
- Change in Resting State Electroencephalogram (EEG)
|
60 |
All |
8 Years to 21 Years (Child, Adult) |
NCT02874690 |
2015-4401 |
SAT |
February 2016 |
October 2018 |
|
August 22, 2016 |
August 25, 2016 |
|
- Cincinnati Children's Hospital Medical Center
Cincinnati, Ohio, United States
|
|
| 139 |
NCT02747056 |
Recruiting |
Study of the Personal Identity in Adults With Autism Spectrum Disorder Without Intellectual Deficiency |
- Autism Spectrum Disorders
|
- Other: clinical, psychological and neuropsychological assessment
- Other: Autobiographical memories Assessment
- Other: Autobiographical memories assessment characteristics
|
Interventional
|
Not Applicable |
- University Hospital, Strasbourg, France
|
Other |
- Allocation: Non-Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Basic Science
|
- The number of details in the memory (A)/The specificity of the memory (B)
- Study A and B: Autistic symptoms questionnaire 1
- Study A and B: Autistic symptoms questionnaire 2
- (and 12 more...)
|
104 |
All |
18 Years to 65 Years (Adult, Older Adult) |
NCT02747056 |
6282 |
TSASDI |
June 2016 |
September 2019 |
December 2019 |
April 21, 2016 |
September 11, 2017 |
|
- Hôpitaux universitaires de Strasbourg
Strasbourg, France
|
|
| 140 |
NCT00760812 |
Completed |
Comparing Parent-Implemented Interventions for Toddlers With Autism Spectrum Disorders |
|
- Behavioral: Early Social Interaction Project- PII
- Behavioral: Early Social Interaction Project- IES
|
Interventional
|
Not Applicable |
- Florida State University
- National Institute of Mental Health (NIMH)
|
Other / NIH |
- Allocation: Randomized
- Intervention Model: Crossover Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Treatment
|
- Child measures of autism symptoms, social communication, developmental level, and adaptive behavior
- Parent report measures of family functioning, daily hassles, and treatment satisfaction
|
82 |
All |
16 Months to 20 Months (Child) |
NCT00760812 |
R01MH077730
1R01MH077730-01A2
1R01MH078165-01A2
DDTR B2-MBA |
|
April 2007 |
May 2013 |
January 2014 |
September 26, 2008 |
February 20, 2014 |
|
- Florida State University
Tallahassee, Florida, United States - University of Michigan
Ann Arbor, Michigan, United States
|
|
| 141 |
NCT00252603 |
Completed |
Galantamine Versus Placebo in Childhood Autism |
|
|
Interventional
|
Phase 3 |
- University of Medicine and Dentistry of New Jersey
- National Alliance for Autism Research
- Rutgers, The State University of New Jersey
|
Other |
- Allocation: Randomized
- Intervention Model: Single Group Assignment
- Masking: Double
- Primary Purpose: Treatment
|
- Autism Diagnostic Observation Schedule-Generic (ADOS-G)- Change from Baseline to Final Visit
- Clinical Global Impression Improvement (CGI)- Change from Baseline to Final Visit
- Aberrant Behavior Checklist (ABC) (hyperactivity/irritability sections)- Change from Baseline to Final Visit
- (and 3 more...)
|
20 |
All |
5 Years to 17 Years (Child) |
NCT00252603 |
4682 |
|
April 2004 |
|
April 2007 |
November 11, 2005 |
January 29, 2007 |
|
- UMDNJ Robert Wood Johnson Medical School - Dept of Psychiatry
Piscataway, New Jersey, United States
|
|
| 142 |
NCT02611921 |
Recruiting |
Study of Intranasal Ketamine for Social Impairment in Autism Spectrum Disorder |
|
- Drug: Ketamine
- Drug: Placebo
|
Interventional
|
Phase 1 |
- Children's Hospital Medical Center, Cincinnati
- Roivant Sciences, Inc.
- Cures Within Reach
|
Other / Industry |
- Allocation: Randomized
- Intervention Model: Crossover Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Change in Social Withdrawal subscale score of the Aberrant Behavior Checklist (ABC)
- Change in the Clinician-rated CGI Improvement scale (CGI-I)
|
24 |
All |
12 Years to 30 Years (Child, Adult) |
NCT02611921 |
2015-2494 |
|
December 2015 |
May 2018 |
December 2018 |
November 23, 2015 |
August 30, 2017 |
|
- Cincinnati Childrens Hospital Medical Center
Cincinnati, Ohio, United States
|
|
| 143 |
NCT02708901 |
Recruiting |
Gut to Brain Interaction in Autism. Role of Probiotics on Clinical, Biochemical and Neurophysiological Parameters |
|
- Dietary Supplement: Vivomixx®
- Dietary Supplement: Placebo
|
Interventional
|
Not Applicable |
- IRCCS Fondazione Stella Maris
- Ministry of Health, Italy
- Istituto di Fisiologia Clinica CNR
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Changes in severity level of ASD symptomatology
- Changes in GI symptomatology
- Changes in Electroencephalogram (EEG) power
- (and 17 more...)
|
100 |
All |
18 Months to 72 Months (Child) |
NCT02708901 |
GR-2011-02348280 |
|
November 2015 |
September 2018 |
November 2018 |
March 15, 2016 |
October 13, 2017 |
|
- IRCCS Stella Maris Foundation
Calambrone, Pisa, Italy
|
|
| 144 |
NCT03204786 |
Recruiting |
Intranasal Vasopressin Treatment in Children With Autism |
- Autism
- Autism Spectrum Disorder
- ASD
|
- Drug: Vasopressin (USP) Injectable Solution [Vasostrict]
- Drug: Placebo
|
Interventional
|
Phase 2 |
- Stanford University
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
|
Other / NIH |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Change from baseline in parent rated Social Responsiveness Scale, Second Edition (SRS-2) total scores during treatment.
- Change from baseline in Clinical Global Impression (CGI) scores during treatment.
- Change from baseline in Vineland Adaptive Behavior Scales, Third Edition (VABS-3) - Social Skills and Relationships Domain during treatment.
- (and 15 more...)
|
100 |
All |
6 Years to 17 Years (Child) |
NCT03204786 |
IRB-39972
1R01HD091972 |
|
February 20, 2018 |
December 2022 |
February 2023 |
July 2, 2017 |
May 21, 2018 |
|
- Stanford University
Stanford, California, United States
|
|
| 145 |
NCT01727466 |
Completed |
Treatment for Children With Autism and Anxiety |
|
- Behavioral: Facing Your Fears
|
Interventional
|
Not Applicable |
- University of Colorado, Denver
- Autism Speaks
|
Other |
- Intervention Model: Single Group Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Treatment
|
- Change in Clinical Global Impression Scale - Improvement and Severity (CGIS-S; CGIS-I)
- Anxiety Disorders Interview Survey for Children-Parent Version (ADIS-P)
|
50 |
All |
8 Years to 14 Years (Child) |
NCT01727466 |
03-0245 |
|
August 2006 |
September 2009 |
December 2009 |
November 16, 2012 |
November 16, 2012 |
|
|
|
| 146 |
NCT03033784 |
Recruiting |
Autism Oxytocin Brain Project |
- Autism
- Autism Spectrum Disorder
|
- Drug: Oxytocin
- Drug: Placebo
|
Interventional
|
Phase 2 |
- Emory University
- National Institute of Mental Health (NIMH)
|
Other / NIH |
- Allocation: Randomized
- Intervention Model: Crossover Assignment
- Masking: Double (Participant, Investigator)
- Primary Purpose: Treatment
|
- Difference in Resting State Functional Connectivity (rsFC)
- Difference in Blood Oxygen Level Dependent (BOLD) Activity in Response to Social Cues
- Difference in Blood Oxygen Level Dependent (BOLD) Activity in Response to Dynamic Social Cues
- (and 5 more...)
|
80 |
Male |
18 Years to 45 Years (Adult) |
NCT03033784 |
IRB00093455
P50MH100023 |
|
May 10, 2017 |
July 2018 |
July 2018 |
January 27, 2017 |
June 1, 2018 |
|
- Emory University
Atlanta, Georgia, United States
|
|
| 147 |
NCT03195465 |
Active, not recruiting |
The Effect of High Antioxidant Cacao on Behaviors in Children With Autism Spectrum Disorder |
|
- Dietary Supplement: Dark Chocolate
|
Interventional
|
Not Applicable |
|
Other |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Supportive Care
|
- Aberrant Behavior Checklist
- Autism Spectrum Rating Scale
|
23 |
All |
5 Years to 18 Years (Child, Adult) |
NCT03195465 |
5170206 |
|
November 14, 2017 |
July 2018 |
July 2018 |
June 22, 2017 |
March 27, 2018 |
|
- Loma Linda University Health
Loma Linda, California, United States
|
|
| 148 |
NCT02508259 |
Completed |
University of California, San Diego (UCSD) Suramin Treatment Trial for Autism |
- Autism Spectrum Disorders
|
- Drug: Suramin
- Drug: Saline
|
Interventional
|
Phase 1
Phase 2 |
- University of California, San Diego
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Joint social attention
- Receptive language
- Social interaction
- (and 9 more...)
|
10 |
Male |
4 Years to 17 Years (Child) |
NCT02508259 |
15-0134 |
|
May 2015 |
March 2016 |
April 2016 |
July 24, 2015 |
April 27, 2016 |
|
- University of California, San Diego School of Medicine
La Jolla, California, United States
|
|
| 149 |
NCT02423499 |
Recruiting |
Features Emotional Responses in Adults With Autism: Comparison With Bipolar Disorder (REMBAU) |
- Autism Spectrum Disorder
- Bipolar Disorder
|
|
Observational
|
|
- University Hospital, Tours
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Physiological emotional response during emotion elicitation in a laboratory session (Pupil size measured by eye tracking, heart rate, electrodermal response, breath rate) during emotion elicitation in a laboratory session
- Subjective emotional response during emotion elicitation in a laboratory session
- Facial emotional response during emotion elicitation in a laboratory session
- (and 2 more...)
|
90 |
All |
18 Years to 50 Years (Adult) |
NCT02423499 |
PHAO13-ML/REMBAU
2014-A00431-46 |
REMBAU |
May 19, 2015 |
May 2019 |
May 2019 |
April 22, 2015 |
November 1, 2017 |
|
|
|
| 150 |
NCT00695812 |
Unknown † |
The Development of Younger Siblings of Children With Autism Now at 10 Years of Age |
- Autism Spectrum Disorders
|
|
Observational
|
|
- Shaare Zedek Medical Center
- Hebrew University of Jerusalem
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
|
104 |
All |
10 Years to 11 Years (Child) |
NCT00695812 |
Siblings Autism.ctil |
|
September 2008 |
September 2011 |
September 2011 |
June 12, 2008 |
June 12, 2008 |
|
|
|
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