| 1 |
NCT00256152 |
Completed |
Asymptomatic Atrial Fibrillation and Stroke Evaluation in Pacemaker Patients and the Atrial Fibrillation Reduction Atrial Pacing Trial |
- Hypertension
- Atrial Fibrillation
|
- Device: AF Suppression Pacing Algorithm
|
Interventional |
Phase 4 |
- St. Jude Medical
- Population Health Research Institute
|
Industry / Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Composite of ischemic stroke & Non-CNS systemic embolism
- Symptomatic or Asymptomatic AT documented by ECG
- Myocardial infarction [MI], Vascular death Composite of stroke, MI or vascular death
|
2580 |
All |
65 Years and older (Adult, Senior) |
NCT00256152 |
CRD291 |
|
September 2004 |
June 2010 |
June 2010 |
November 21, 2005 |
July 30, 2012 |
|
- McMaster University
Hamilton, Ontario, Canada
|
| 2 |
NCT02937077 |
Recruiting |
Atrial Fibrillation in Cryptogenic Stroke and TIA |
- Atrial Fibrillation
- Ischemic Stroke
- TIA
|
- Device: Medtronic Reveal LINQ
|
Observational |
|
- Oslo University Hospital
- Ostfold Hospital Trust
- Haukeland University Hospital
- (and 8 more...)
|
Other |
- Observational Model: Case-Only
- Time Perspective: Prospective
|
- Atrial fibrillation detection rate
- AF detection rate
- Levels of miRNAs related to atrial fibrillation
- (and 8 more...)
|
500 |
All |
18 Years to 80 Years (Adult, Senior) |
NCT02937077 |
2013/2371 |
NOR-FIB |
December 2016 |
June 2018 |
December 2018 |
October 18, 2016 |
February 7, 2017 |
|
- Østfold Hospital Trust
Kalnes, Grålum, Norway - Oslo University Hospital
Oslo, Norway
|
| 3 |
NCT02004509 |
Not yet recruiting |
SILENT - Subclinical AtrIal FibrilLation and StrokE PreveNtion Trial |
|
- Drug: anticoagulant by physician criteria
|
Interventional |
Phase 4 |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Stroke
- Systemic embolism
- Subclinical AF rate
- (and 5 more...)
|
2054 |
All |
18 Years and older (Adult, Senior) |
NCT02004509 |
SILENT |
SILENT |
February 2015 |
October 2020 |
October 2020 |
December 9, 2013 |
September 9, 2014 |
|
|
| 4 |
NCT03466125 |
Active, not recruiting |
Characterization and Prediction of Atrial Fibrillation-caused Adverse Events After Hospital Discharge for Cardiac Surgery |
- Atrial Fibrillation
- Stroke, Acute
- Death
|
- Procedure: Cardiac surgery
|
Observational |
|
- Brigham and Women's Hospital
- Beth Israel Deaconess Medical Center
- Massachusetts General Hospital
- (and 7 more...)
|
Other |
- Observational Model: Cohort
- Time Perspective: Retrospective
|
- Recurrent atrial fibrillation
- Acute ischemic stroke
- Mortality
|
50000 |
All |
20 Years and older (Adult, Senior) |
NCT03466125 |
2017P002261/PHS |
MATRICeS |
January 1, 2018 |
December 31, 2019 |
December 31, 2019 |
March 15, 2018 |
March 15, 2018 |
|
- Brigham and Women's Hospital
Boston, Massachusetts, United States
|
| 5 |
NCT02014896 |
Recruiting |
Ischemia Care Biomarkers of Acute Stroke Etiology (BASE) |
- Ischemic Stroke
- Atrial Fibrillation
- Transient Ischemic Attacks
- (and 4 more...)
|
- Other: Biomarker blood draw
|
Observational |
|
|
Industry |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Cardioembolic and large vessel stroke stiology
- TIA differentiation from non ischemic events (TNE).
- Cryptogenic stroke
- (and 2 more...)
|
1400 |
All |
18 Years and older (Adult, Senior) |
NCT02014896 |
ISCH01 |
BASE |
December 2013 |
March 2018 |
December 2018 |
December 18, 2013 |
August 11, 2017 |
|
- Dignity Health Mercury San Juan
Sacramento, California, United States - Zuckerberg San Francisco General Hospital (UCSF)
San Francisco, California, United States - University of California San Francisco Medical Center Hospital
San Francisco, California, United States - (and 19 more...)
|
| 6 |
NCT01325545 |
Completed |
Detection of Occult Paroxysmal Atrial Fibrillation After Stroke Using Prolonged Ambulatory Cardiac Monitoring |
- Stroke
- Atrial Fibrillation
|
- Other: Mobile cardiac rhythm monitoring
|
Observational |
|
|
Other / Industry |
- Observational Model: Case Control
- Time Perspective: Prospective
|
- Detection of Atrial Fibrillation
- Time to first episode of atrial fibrillation
- Atrial Fibrillation Load
- (and 3 more...)
|
132 |
All |
18 Years and older (Adult, Senior) |
NCT01325545 |
08-003788 |
|
April 2009 |
March 2011 |
March 2011 |
March 29, 2011 |
December 23, 2011 |
|
|
| 7 |
NCT02606890 |
Completed |
Stroke Lesion Pattern on MRI and Atrial Fibrillation |
- Stroke
- Atrial Fibrillation
|
|
Observational |
|
- Charite University, Berlin, Germany
|
Other |
- Observational Model: Cohort
- Time Perspective: Retrospective
|
- Lesion pattern on Magnetic Resonance Imaging in acute stroke patients
- Lesion pattern on Magnetic Resonance Imaging in acute stroke patients (DWI only)
|
1000 |
All |
18 Years and older (Adult, Senior) |
NCT02606890 |
AGNO_001 |
SLPAF |
August 2015 |
October 2016 |
December 2016 |
November 17, 2015 |
December 8, 2016 |
|
|
| 8 |
NCT02204267 |
Active, not recruiting |
Impact of Standardized MONitoring for Detection of Atrial Fibrillation in Ischemic Stroke |
- Stroke
- Atrial Fibrillation
|
- Other: prolonged ECG monitoring
- Device: ECG
|
Interventional |
Not Applicable |
- Charite University, Berlin, Germany
- Bayer Healthcare Pharmaceuticals, Inc./Bayer Schering Pharma
|
Other / Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Diagnostic
|
- Number of patients on oral anticoagulation (NOAC or VKA)
- Number of stroke patients with newly detected atrial fibrillation
|
3470 |
All |
18 Years and older (Adult, Senior) |
NCT02204267 |
MonDAFIS
EA2/033/14 |
MonDAFIS |
December 2014 |
December 2018 |
December 2019 |
July 30, 2014 |
October 12, 2017 |
|
- Charité Universitaetsmedizin Berlin
Berlin, Germany
|
| 9 |
NCT01160406 |
Completed |
Screening for Atrial Fibrillation, After Ischemic Stroke |
- Atrial Fibrillation
- Stroke
|
|
Observational |
|
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
|
250 |
All |
Child, Adult, Senior |
NCT01160406 |
KI-DSAB-2010 |
|
June 2007 |
November 2010 |
November 2010 |
July 12, 2010 |
June 27, 2011 |
|
- Halmstad hospital
Halmstad, Halland, Sweden - South hospital
Stockholm, Sweden - Danderyds hospital AB
Stockholm, Sweden
|
| 10 |
NCT01858779 |
Unknown † |
Know Your Pulse Post Stroke-Measurement of Peripheral Pulse for Detection of Atrial Fibrillation After Ischemic Stroke |
- Stroke
- Atrial Fibrillation
|
- Behavioral: Measurement of peripheral pulse
- Device: 72h holter ECG
|
Observational |
|
- University of Erlangen-Nürnberg Medical School
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Number of newly detected cases of atrial fibrillation
- Comparison of detection rates by MPP and by serial holter ECG (3 months, 6 months)
- Timepoint of detection of atrial fibrillation by MPP or holter ECG
- (and 2 more...)
|
300 |
All |
50 Years and older (Adult, Senior) |
NCT01858779 |
DE-ER-KYP |
|
May 2013 |
April 2015 |
October 2015 |
May 21, 2013 |
June 3, 2013 |
|
- Universitätsklinikum Erlangen; Dept. of Neurology
Erlangen, Bavaria, Germany
|
| 11 |
NCT02641678 |
Completed |
Follow-up of Kryptogenic Stroke Patients With Implantable vs. Non-invasive Devices to Detect Atrial Fibrillation. |
- Atrial Fibrillation
- Stroke
|
- Device: Implantation of cardiac monitor
|
Observational |
|
- University Hospital Muenster
- European Union
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- To determine the prevalence of undiagnosed AF in stroke patients undergoing the diagnostic standard (24h-ECG)
- Diagnostic accuracy of the automated software based ECG analysis in comparison to the "gold-standard" the implanted cardiac monitor
|
106 |
All |
18 Years and older (Adult, Senior) |
NCT02641678 |
TRACK-AF |
TRACK-AF |
March 2013 |
December 2014 |
June 2015 |
December 29, 2015 |
January 21, 2016 |
|
|
| 12 |
NCT02725944 |
Recruiting |
Prediction and Detection of Occult Atrial Fibrillation in Patients After Acute Cryptogenic Stroke and TIA |
- Cerebrovascular Stroke
- Atrial Fibrillation
|
- Device: Implantation of ICRM
|
Observational |
|
- University Hospital, Akershus
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Detection of paroxysmal atrial fibrillation
|
250 |
All |
18 Years and older (Adult, Senior) |
NCT02725944 |
2014/1260 D (REK) |
PROACTIA |
May 2016 |
June 2018 |
December 2018 |
April 1, 2016 |
January 9, 2018 |
|
- Loreta Skrebelyte-Strøm
Oslo, Akershus, Norway
|
| 13 |
NCT02216370 |
Recruiting |
Detection of Occult Paroxysmal AF in Cryptogenic Stroke or TIA Patients Using an Implantable Loop Recorder and Correlation With Genetic Markers. |
- Cryptogenic Stroke or TIA
- Atrial Fibrillation
|
|
Observational |
|
- University Hospital, Martin
|
Other |
- Observational Model: Case Control
- Time Perspective: Prospective
|
- Documented Atrial Fibrillation after episode of cryptogenic stroke / TIA Documented genetic mutation PITX2 and ZFHX3
- Time to documented Atrial Fibrillation Reccurent stroke or TIA Stroke Secondary Prevention Therapy changes within 12 months Neuroimaging Changes ( brain CT/ MRI)
|
125 |
All |
18 Years to 65 Years (Adult) |
NCT02216370 |
NRRXT0001 |
|
April 2014 |
June 2018 |
June 2018 |
August 13, 2014 |
August 13, 2014 |
|
- Faculty Hospital Nitra
Nitra, Slovakia
|
| 14 |
NCT03126214 |
Recruiting |
Improving Stroke Prevention in Atrial Fibrillation Through Pharmacist Prescribing |
- Atrial Fibrillation
- Stroke
|
|
Interventional |
Phase 4 |
- University of Alberta
- Heart and Stroke Foundation of Canada
- Canadian Stroke Prevention Intervention Network
|
Other |
- Allocation: Randomized
- Intervention Model: Crossover Assignment
- Masking: None (Open Label)
- Primary Purpose: Prevention
|
- Optimal Oral Anticoagulant (OAC) Therapy for Atrial Fibrillation Stroke Prevention
- Prevalence of AF
- Patient Satisfaction with Pharmacists Services
- (and 2 more...)
|
370 |
All |
65 Years and older (Adult, Senior) |
NCT03126214 |
0024466 |
PIAAF Rx |
November 15, 2017 |
May 1, 2019 |
September 1, 2019 |
April 24, 2017 |
November 1, 2017 |
|
- University of Alberta
Edmonton, Alberta, Canada
|
| 15 |
NCT02180542 |
Completed |
Atrial Fibrillation and Premature Atrial Complexes in Patients With Ischemic Stroke. |
- Stroke
- Atrial Fibrillation
- Premature Atrial Complexes
|
|
Observational |
|
- Odense University Hospital
- University of Southern Denmark
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- time to death and recurrent stroke
- Time to death, recurrent stroke and atrial fibrillation
- Left atrial volume and function estimated by echocardiography
|
264 |
All |
18 Years and older (Adult, Senior) |
NCT02180542 |
Pacific |
Pacific |
March 2012 |
August 2015 |
October 2016 |
July 2, 2014 |
October 11, 2017 |
|
- Department of Medical Research, OUH, Svendborg
Svendborg, Funen, Denmark
|
| 16 |
NCT02961348 |
Recruiting |
TIMING of Oral Anticoagulant Therapy in Acute Ischemic Stroke With Atrial Fibrillation |
- Ischemic Stroke
- Atrial Fibrillation
|
- Other: Early start of NOAC
- Other: Late start of NOAC
|
Interventional |
Not Applicable |
- Uppsala University
- The Swedish Stroke Register (Riksstroke)
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Prevention
|
- Composite outcome of recurrent ischemic stroke, symptomatic intracerebral hemorrhage, or all-cause mortality
- Recurrent acute ischemic stroke
- Symptomatic intracerebral hemorrhage (S-ICH)
- (and 3 more...)
|
3000 |
All |
18 Years and older (Adult, Senior) |
NCT02961348 |
U-2015-341
2015-00881 |
|
February 15, 2017 |
May 2019 |
December 2020 |
November 10, 2016 |
October 19, 2017 |
|
- Alingås Hospital
Alingsås, Sweden - Enköping Hospital
Enköping, Sweden - Mälarsjukhuset Hospital
Eskilstuna, Sweden - (and 17 more...)
|
| 17 |
NCT01410396 |
Completed |
Occult Paroxysmal Atrial Fibrillation in Patients With Non-cardioembolic Ischemic Stroke of Determined Mechanism |
- Atrial Fibrillation
- Stroke
|
|
Observational |
|
- Northwestern University
- LifeWatch Services, Inc.
|
Other / Industry |
- Observational Model: Case Control
- Time Perspective: Prospective
|
- Detection of any episode of AF >30 seconds during 21 days of mobile outpatient cardiac telemetry
- Recurrent ischemic stroke
|
49 |
All |
50 Years and older (Adult, Senior) |
NCT01410396 |
Lifewatch |
|
April 2010 |
May 2012 |
May 2013 |
August 5, 2011 |
August 15, 2013 |
|
- Northwestern University
Chicago, Illinois, United States
|
| 18 |
NCT01550042 |
Active, not recruiting |
Extended Rhythm SCreening for AtRial Fibrillation in Cryptogenic Stroke Patients |
- Atrial Fibrillation
- Stroke
|
|
Observational |
|
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Documented Atrial Fibrillation (AF)
- Time to documented AF
- Recurrent stroke
|
50 |
All |
18 Years and older (Adult, Senior) |
NCT01550042 |
NL36491.044.11
P11-25 |
SCARF |
September 2011 |
April 2015 |
April 2017 |
March 9, 2012 |
July 7, 2016 |
|
- Medisch Spectrum Twente / Thoraxcenter
Enschede, OV, Netherlands
|
| 19 |
NCT02344901 |
Completed |
ReAl-life Multicentre Survey Evaluating Stroke Prevention Strategies (RAMSES) |
- Thrombotic Stroke
- Atrial Fibrillation and Flutter
|
|
Observational |
|
- Muğla Sıtkı Koçman University
|
Other |
- Observational Model: Cohort
- Time Perspective: Cross-Sectional
|
- The number of patients with non-valvular atrial fibrillation receiving appropriate oral anticoagulant for stroke prevention
- creatinine clearance of patients
- time in therapeutic range of warfarin using patients
- (and 2 more...)
|
6273 |
All |
18 Years and older (Adult, Senior) |
NCT02344901 |
RAMSES |
RAMSES |
February 2015 |
April 2015 |
May 2015 |
January 26, 2015 |
September 23, 2015 |
|
- Adana Numune Education and Research Hospital
Adana, Turkey - Ankara Kecioren Education and Research Hospital
Ankara, Turkey - Diskapi Yidirim Beyazit Education and Research Hospital
Ankara, Turkey - (and 59 more...)
|
| 20 |
NCT03258645 |
Not yet recruiting |
This Study Uses the SITS Registry to Find Out When Patients With a Heart Rhythm Disorder (Atrial Fibrillation) Start Treatment With Dabigatran After They Had a Stroke |
|
|
Observational |
|
- Boehringer Ingelheim
- SITS international, Karolinska University Hospital, Stockholm, Sweden
|
Industry / Other |
- Observational Model: Case-Only
- Time Perspective: Retrospective
|
- timing of dabigatran treatment initiation after a first ever ischaemic stroke (index event) in NVAF patients
- Description of baseline characteristics for patients treated with dabigatran according to time of dabigatran initiation
- Description of self-reported factors important for physician's decision when to initiate dabigatran and which dabigatran dose is used in the post-ischemic stroke setting for secondary prevention of stroke and safety in NVAF
|
1000 |
All |
18 Years and older (Adult, Senior) |
NCT03258645 |
1160.235 |
|
May 31, 2018 |
July 31, 2018 |
July 31, 2018 |
August 23, 2017 |
April 4, 2018 |
|
|
| 21 |
NCT02635685 |
Active, not recruiting |
Clinical Decision Support for Stroke Prevention in Atrial Fibrillation |
- Cardiovascular Disease
- Atrial Fibrillation
- Stroke
|
- Other: Clinical Decision Support tool
|
Interventional |
Not Applicable |
- University Hospital, Linkoeping
- Linkoeping University
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Prevention
|
- Adherence to guidelines defined as the percentage of patients with atrial fibrillation and CHA2DS2VASc ≥ 1, (not only female gender) that are prescribed anticoagulant therapy (ATC-code B01A).
- Reduction av thromboembolism. This will be analyzed through the electronic medical journal by identifying the patients with new (since commencement of the study) diagnosis of thromboembolism. ICD-10 codes I63-64, G45, I75 will be analyzed.
- Analysis of physician acceptance of a clinical decision tool in the primary care setting with questionnaires to randomly assigned general physicians.
- (and 2 more...)
|
442105 |
All |
Child, Adult, Senior |
NCT02635685 |
2015/398-32 |
CDS-AF |
January 11, 2016 |
January 11, 2017 |
January 11, 2023 |
December 21, 2015 |
October 26, 2017 |
|
- The County of Östergötland
Linköping, Sweden
|
| 22 |
NCT02610803 |
Completed |
Paroxysmal Atrial Fibrillation in Patients With Acute Ischemic Stroke |
- Ischemic Stroke
- Paroxysmal Atrial Fibrillation
- Premature Atrial Complexes
|
|
Observational |
|
- Odense University Hospital
|
Other |
- Observational Model: Cohort
- Time Perspective: Retrospective
|
- Time to death or recurrent stroke
- Number of patients diagnosed with atrial fibrillation by 48 hours' continuous inpatient cardiac telemetry
- Number of patients diagnosed with runs of premature atrial complexes by 48 hours' continuous cardiac telemetry
- (and 2 more...)
|
863 |
All |
18 Years and older (Adult, Senior) |
NCT02610803 |
HISPACs |
|
September 2014 |
September 2015 |
October 2015 |
November 20, 2015 |
November 20, 2015 |
|
- Department of Medical Research, OUH, Svendborg
Svendborg, Funen, Denmark
|
| 23 |
NCT01581502 |
Unknown † |
SAMURAI-NVAF Study: Anticoagulant Therapy for Japanese Stroke Patients With Nonvalvular Atrial Fibrillation (NVAF) |
- Stroke, Acute
- Atrial Fibrillation
|
- Other: This is an observational study.
|
Observational |
|
- Ministry of Health, Labour and Welfare, Japan
|
Other |
- Observational Model: Case-Only
- Time Perspective: Prospective
|
- Ischemic events
- major bleeding
- modified Rankin Scale
- Modification of anticoagulant medication
|
1000 |
All |
Child, Adult, Senior |
NCT01581502 |
samurai2011
samurai nvaf 2011 |
SAMURAI-NVAF |
September 2011 |
March 2016 |
December 2016 |
April 20, 2012 |
September 2, 2015 |
|
- National Hospital Organization Nagoya Medical Center
Nagoya, Aichi, Japan - Toyota Memorial Hospital
Toyota, Aichi, Japan - Brain Attack Center Ota Memorial Hospital
Fukuyama, Hiroshima, Japan - (and 13 more...)
|
| 24 |
NCT02232022 |
Completed |
Occult Paroxysmal Atrial Fibrillation in Non-Cryptogenic Ischemic Stroke |
|
- Device: Reveal LINQ Insertable Cardiac Monitor
|
Interventional |
Not Applicable |
|
Other |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Diagnostic
|
- The incidence of paroxysmal atrial fibrillation (AF) in ischemic stroke patients who have a presumed known stroke etiology other than atrial fibrillation
- Percentage of patients who are diagnosed with AF who are changed to anticoagulant therapy.
- Duration and frequency of AF episodes.
- (and 2 more...)
|
54 |
All |
41 Years and older (Adult, Senior) |
NCT02232022 |
14-336 |
|
September 1, 2014 |
September 28, 2017 |
September 28, 2017 |
September 4, 2014 |
November 14, 2017 |
|
- North Shore University Hospital
Manhasset, New York, United States - Long Island Jewish Medical Center
New Hyde Park, New York, United States
|
| 25 |
NCT02339493 |
Recruiting |
Electronic Alerts for Stroke Prevention in Patients With Atrial Fibrillation or Atrial Flutter |
- Atrial Fibrillation
- Stroke
|
- Other: Computer Electronic Alert
|
Interventional |
Not Applicable |
- Brigham and Women's Hospital
- Daiichi Sankyo, Inc.
|
Other / Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Participant)
- Primary Purpose: Prevention
|
- Frequency of stroke or systemic embolism at 3 months after randomization
- Stroke defined clinically as a sudden onset focal neurological deficit in a location consistent with the territory of a major cerebral artery and will be categorized as ischemic, hemorrhagic, or unspecified.
- Systemic embolism defined as an acute vascular occlusion of an extremity or organ as documented by means of imaging, surgery, or autopsy.
- (and 2 more...)
|
1000 |
All |
21 Years and older (Adult, Senior) |
NCT02339493 |
2014P002317 |
|
May 2016 |
June 2017 |
December 2017 |
January 15, 2015 |
November 3, 2016 |
|
- Brigham and Women's Hospital
Boston, Massachusetts, United States
|
| 26 |
NCT02958943 |
Not yet recruiting |
Electronic Alerts for Stroke Prevention in Atrial Fibrillation |
- Atrial Fibrillation
- Stroke
|
- Behavioral: On-screen electronic alert
|
Interventional |
Not Applicable |
- Brigham and Women's Hospital
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Investigator)
- Primary Purpose: Treatment
|
- frequency of prescription of anticoagulation in high-risk AF patients in the outpatient setting who are not being prescribed anticoagulation
- major bleeding (as defined by the ISTH bleeding classification system)
- frequency of stroke, systemic embolism, and all-cause mortality
|
400 |
All |
18 Years and older (Adult, Senior) |
NCT02958943 |
2016D005336 |
|
January 2017 |
December 2019 |
|
November 8, 2016 |
November 8, 2016 |
|
- Brigham and Women's Hospital
Boston, Massachusetts, United States
|
| 27 |
NCT02485873 |
Completed |
Real-Life Evidence on Stroke Prevention in SPAF |
- Atrial Fibrillation (Prevention of Stroke)
|
- Drug: Rivaroxaban (Xarelto, BAY59-7939)
- Drug: Vitamin K antagonists
|
Observational |
|
|
Industry |
- Observational Model: Cohort
- Time Perspective: Retrospective
|
- Time to first occurrence of any of the following: Ischemic stroke (IS), Transient ischemic attack (TIA), Intracerebral hemorrhage (IH), Other non-traumatic intracranial hemorrhage including subdural hemorrhage, Myocardial infarction (MI)
- Time to first occurrence of IS
- Time to first occurrence of TIA
- (and 9 more...)
|
8607 |
All |
18 Years and older (Adult, Senior) |
NCT02485873 |
18073
DBOX 2014/00799 |
RELIEF |
May 2015 |
September 2015 |
September 2015 |
June 30, 2015 |
November 11, 2015 |
|
|
| 28 |
NCT01855035 |
Active, not recruiting |
Finding Atrial Fibrillation in Stroke - Evaluation of Enhanced and Prolonged Holter Monitoring |
|
- Other: prolonged ECG monitoring
- Other: standard care
|
Interventional |
Not Applicable |
- Institut fuer anwendungsorientierte Forschung und klinische Studien GmbH
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Prevention
|
- number of atrial fibrillation/flutter
- number of atrial fibrillation (/flutter) within 12 months after patient's inclusion
- number of atrial fibrillation (/flutter) without hospitalisation
- (and 11 more...)
|
400 |
All |
60 Years and older (Adult, Senior) |
NCT01855035 |
Find-AF randomised |
|
May 2013 |
August 2017 |
October 2017 |
May 16, 2013 |
February 27, 2017 |
|
- Dept. of Cardiology and Pneumology, University Medical Center Goettingen
Goettingen, Germany - Clinic and Policlinic for Neurology, University of Mainz
Mainz, Germany - Dept. of Neurology, Nordwest-Hospital Sanderbusch
Sande, Germany - Dept. of Neurology, HSK, Dr. Horst-Schmidt-Hospital
Wiesbaden, Germany
|
| 29 |
NCT02374359 |
Unknown † |
Atrial Tachycardia as a Predictor of Atrial Fibrillation, Stroke and Mortality in Cryptogenic Stroke |
- Cryptogenic Stroke
- Atrial Fibrillation
- Atrial Tachycardia
|
|
Observational |
|
|
Other |
- Observational Model: Cohort
- Time Perspective: Retrospective
|
- ischemic stroke
- atrial fibrillation
- cardiovascular mortality
- global mortality
|
210 |
All |
Child, Adult, Senior |
NCT02374359 |
CPTCAR-EP201501 |
|
January 2015 |
February 2015 |
February 2015 |
February 27, 2015 |
February 27, 2015 |
|
- Corporacio Sanitaria Parc Tauli
Sabadell, Barcelona, Spain
|
| 30 |
NCT01924065 |
Active, not recruiting |
Risk of Stroke and Silent Cerebrovascular Thromboembolism After Cardioversion of Atrial Fibrillation |
- Atrial Fibrillation
- Cardioversion
- Cerebrovascular Stroke
|
- Procedure: Cardioversion
- Drug: Oral Anticoagulant
|
Interventional |
Phase 3 |
- Suleyman Demirel University
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Ischemic stroke or silent cerebral thromboemboli
- Any clinical thromboembolic or hemorrhagic event or death
|
108 |
All |
18 Years to 85 Years (Adult, Senior) |
NCT01924065 |
ozaydin291 |
AFTER-CV |
August 2013 |
August 2017 |
August 2018 |
August 16, 2013 |
November 30, 2017 |
|
- Suleyman Demirel University
Isparta, Mediterranean Region, Turkey
|
| 31 |
NCT03479073 |
Recruiting
New |
Risk Factors of Stroke or Systemic Embolism After Atrial Fibrillation Ablation |
|
|
Observational |
|
- Korea University Guro Hospital
- Hanmi Pharmaceutical Company Limited
|
Other / Industry |
- Observational Model: Cohort
- Time Perspective: Retrospective
|
- Incidence of stroke or systemic embolism
|
3500 |
All |
Child, Adult, Senior |
NCT03479073 |
KUGH17098-001 |
|
May 17, 2017 |
June 15, 2018 |
September 15, 2018 |
March 27, 2018 |
March 27, 2018 |
|
- Korea University Anam Hospital
Seoul, Korea, Republic of - Korea University Guro Hospital
Seoul, Korea, Republic of - Seoul National University Hospital
Seoul, Korea, Republic of
|
| 32 |
NCT01025947 |
Unknown † |
"Cryptogenic Stroke and Atrial Fibrillation Detection Through Implantable Loop Recorder (ILR)" |
- Atrial Fibrillation
- Stroke
|
|
Observational |
|
- University of Valencia
- Hospital Universitario Virgen de la Arrixaca
- Universidad de Murcia
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- First AF episode detected by the implantable loop recorder in patients that had a cryptogenic stroke. An AF episode will be considered an AF episode that lasts at least 2 minutes.
- All subsequent AF episodes detected by the ILR after primary outcome (AF burden)
- AF episodes detected by external monitoring
- (and 2 more...)
|
100 |
All |
45 Years to 85 Years (Adult, Senior) |
NCT01025947 |
HCUV |
CRYPTONITE |
March 2009 |
March 2013 |
March 2013 |
December 4, 2009 |
June 28, 2010 |
|
- Hospital Universitario Virgen de la Arrixaca
Murcia, Spain - Hospital Clinico Universitario de Valencia
Valencia, Spain
|
| 33 |
NCT02578979 |
Recruiting |
Serial ECG Versus Holter to Detect Atrial Fibrillation in Elderly Ischemic Stroke Patients |
|
- Device: Electrocardiogram
- Device: Holter
|
Interventional |
Not Applicable |
- Chang Gung Memorial Hospital
- National Taiwan University Hospital
- Chiayi Christian Hospital
- Dalin Tzu Chi General Hospital
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Diagnostic
|
- Number of atrial fibrillation detected
|
600 |
All |
65 Years and older (Adult, Senior) |
NCT02578979 |
NMRPD1E0891 |
|
August 2015 |
July 2018 |
July 2018 |
October 19, 2015 |
October 19, 2015 |
|
- Chia-yi Christian Hospital
Chiayi City, Taiwan - Dalin Tzu Chi General Hospital
Chiayi County, Taiwan - Chang Gung Memorial Hospital, Keelung Branch
Keelung, Taiwan - (and 3 more...)
|
| 34 |
NCT01288352 |
Active, not recruiting |
Early Treatment of Atrial Fibrillation for Stroke Prevention Trial |
- Atrial Fibrillation
- Stroke
|
- Other: early standardised rhythm control
|
Interventional |
Phase 4 |
- Atrial Fibrillation Network
- Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK)
- Sanofi
- (and 2 more...)
|
Other / Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Prevention
|
- A composite of cardiovascular death, stroke and hospitalization due to worsening of heart failure or due to acute coronary syndrome.
- Cardiovascular death
- stroke
- (and 8 more...)
|
2789 |
All |
18 Years and older (Adult, Senior) |
NCT01288352 |
AFNET 4 EAST
2010-021258-20 |
EAST |
February 2011 |
June 2019 |
November 2019 |
February 2, 2011 |
February 6, 2017 |
|
- 14 Sites
Different, Belgium - 4 Sites
Different, Czech Republic - 2 Sites
Different, Denmark - (and 8 more...)
|
| 35 |
NCT03148457 |
Recruiting |
Early Versus Late Initiation of Direct Oral Anticoagulants in Post-ischaemic Stroke Patients With Atrial fibrillatioN (ELAN): an International, Multicentre, Randomised-controlled, Two-arm, Assessor-blinded Trial |
|
- Drug: Early treatment with Rivaroxaban (Xarelto®), Dabigatran (Pradaxa®), Apixaban (Eliquis®) or Edoxaban (Lixiana®)
- Drug: Late treatment with Rivaroxaban (Xarelto®), Dabigatran (Pradaxa®), Apixaban (Eliquis®) or Edoxaban (Lixiana®)
|
Interventional |
Not Applicable |
- University Hospital Inselspital, Berne
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Treatment
|
- Composite of major bleeding, recurrent ischaemic stroke, systemic embolism and/or vascular death
- Modified Rankin Scale (mRS)
- Major bleeding
- (and 13 more...)
|
2000 |
All |
18 Years and older (Adult, Senior) |
NCT03148457 |
2017-00588 |
ELAN |
November 6, 2017 |
August 30, 2021 |
October 31, 2021 |
May 11, 2017 |
March 23, 2018 |
|
- Universitätsklinikum Hamburg-Eppendorf
Hamburg, Germany - Dept. of Medicine, University of Thessaly
Larissa, Thessaly, Greece - Dept. of Neurology, Kantonsspital Aarau
Aarau, Aargau, Switzerland - (and 12 more...)
|
| 36 |
NCT02810509 |
Recruiting |
Quality of Anticoagulation With Warfarin in Patient With Atrial Fibrillation for Secondary Stroke Prevention in Korea |
- Atrial Fibrillation
- Stroke
|
|
Observational |
|
|
Other |
- Observational Model: Cohort
- Time Perspective: Retrospective
|
- Time in TTR, the proportion of time in the therapeutic range of INR between 2.0-3.0.
- Proportion of INR in the therapeutic range of 2.0-3.0: numbers of INR within the therapeutic range by the total numbers of INR measured.
|
2217 |
All |
Child, Adult, Senior |
NCT02810509 |
Warfarin TTR-01 |
|
June 2015 |
October 2016 |
December 2017 |
June 23, 2016 |
June 23, 2016 |
|
- Hallym University College of Medicine
Anyang, Korea, Republic of - Dong-A University College of Medicine
Busan, Korea, Republic of - Yeungnam University School of Medicine
Daegu, Korea, Republic of - (and 15 more...)
|
| 37 |
NCT02261766 |
Completed |
Evaluation of 5 Days Holter and 30 Days Thumb-ECG for Detection of Atrial Fibrillation in Stroke Patients |
- Atrial Fibrillation
- Stroke
|
- Device: Holter monitoring and Thumb ECG
|
Interventional |
Not Applicable |
|
Other |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Prevention
|
- Atrial fibrillation detection rate on Thumb-ECG
- Atrial fibrillation detection rate on holtermonitoring
- Time to detection of atrial fibrillation on holter
- Time to detection af atrial fibrillation on thumb-ECG
|
100 |
All |
65 Years and older (Adult, Senior) |
NCT02261766 |
EHOT001 |
EHOT |
August 2012 |
February 2015 |
June 2015 |
October 10, 2014 |
June 24, 2015 |
|
- Department of Neurology, Herlev Hospital
Herlev, Denmark
|
| 38 |
NCT02830152 |
Recruiting |
Prevention of Stroke by Left Atrial Appendage Closure in Atrial Fibrillation Patients After Intracerebral Hemorrhage |
- Atrial Fibrillation
- Stroke
- Intracerebral Hemorrhage
|
- Device: LAAO
- Drug: Medical Therapy
|
Interventional |
Not Applicable |
- Karolinska University Hospital
- St. Jude Medical
|
Other / Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Prevention
|
- Composite endpoint of stroke (ischemic or hemorrhagic), systemic embolism, life-threatening or major bleeding and all-cause mortality
- Number of participants with a device-related complication
- Number of Participants with a device success
- (and 8 more...)
|
750 |
All |
18 Years and older (Adult, Senior) |
NCT02830152 |
STROKECLOSE |
|
May 3, 2017 |
May 2022 |
May 2030 |
July 12, 2016 |
May 18, 2017 |
|
- Sahlrenska University Hospital
Göteborg, Sweden - Danderyd Hospital
Stockholm, Sweden
|
| 39 |
NCT02784717 |
Recruiting |
Xarelto on Prevention of Stroke and Non-central Nervous System Systemic Embolism in Patients With Non-valvular Atrial Fibrillation in China: A Non-interventional Study |
|
- Drug: Rivaroxaban (Xarelto, BAY 59-7939)
|
Observational |
|
- Bayer
- Janssen Scientific Affairs, LLC
|
Industry |
- Observational Model: Case-Only
- Time Perspective: Prospective
|
- Number of Major bleeding events
- Number of Symptomatic thromboembolic events
- Number of Non-major bleeding
- (and 3 more...)
|
6000 |
All |
18 Years and older (Adult, Senior) |
NCT02784717 |
16819
XA1207CN |
XASSURE |
May 11, 2016 |
June 30, 2021 |
August 30, 2021 |
May 27, 2016 |
April 5, 2018 |
|
|
| 40 |
NCT02156765 |
Unknown † |
China Atrial Fibrillation Screening in Acute Ischemic Stroke Patients |
- Atrial Fibrillation
- Stroke
|
|
Observational |
|
- yongjun wang
- Ministry of Science and Technology of the People´s Republic of China
|
Other |
- Time Perspective: Prospective
|
- Accumulated detection rate of AF
|
3000 |
All |
18 Years and older (Adult, Senior) |
NCT02156765 |
TTYY-20140410 |
CRIST |
October 2013 |
March 2015 |
March 2015 |
June 5, 2014 |
June 5, 2014 |
|
- Beijing Stroke Association
Beijing, Beijing, China
|
| 41 |
NCT02129920 |
Unknown † |
RELAXED: Recurrent Embolism Lessened by Rivaroxaban for Acute Ischemic Stroke |
- Stroke, Acute
- Atrial Fibrillation
|
- Other: This is an observational study
|
Observational |
|
- Japan Cardiovascular Research Foundation
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Recurrent ischemic stroke and major bleeding
- ischemic stroke and transient ischemic attack
- Composite cardiovascular events
- (and 10 more...)
|
2000 |
All |
20 Years and older (Adult, Senior) |
NCT02129920 |
M25-113 |
RELAXED |
February 2014 |
May 2016 |
May 2016 |
May 2, 2014 |
May 2, 2014 |
|
- Japan Cardiovascular Research Foundation
Suita, Osaka, Japan
|
| 42 |
NCT01606995 |
Completed |
Xarelto for Prevention of Stroke in Patients With Atrial Fibrillation |
|
- Drug: Rivaroxaban (Xarelto, BAY59-7939)
|
Observational |
|
- Bayer
- Janssen Research & Development, LLC
|
Industry |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Adjudicated major bleeding events
- Safety variables will be summarized using descriptive statistics based on adverse events collection
- All cause mortality
- (and 2 more...)
|
6784 |
All |
18 Years and older (Adult, Senior) |
NCT01606995 |
15914
XA1101 |
XANTUS |
June 2012 |
March 2015 |
March 2015 |
May 28, 2012 |
January 23, 2017 |
|
- Many Locations, Austria
- Many Locations, Belgium
- Many Locations, Canada
- (and 18 more...)
|
| 43 |
NCT01750788 |
Completed |
Xarelto for Prevention of Stroke in Patients With Atrial Fibrillation in Asia |
|
- Drug: Rivaroxaban (Xarelto, BAY59-7939)
|
Observational |
|
- Bayer
- Janssen Research & Development, LLC
|
Industry |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Adjudicated major bleeding events
- Safety variables will be summarized using descriptive statistics based on adverse events collection
- All cause mortality
- (and 8 more...)
|
2297 |
All |
18 Years and older (Adult, Senior) |
NCT01750788 |
16371
XA1205 |
XANAP |
January 13, 2013 |
October 12, 2015 |
October 12, 2015 |
December 17, 2012 |
September 21, 2017 |
|
- Many Locations, Hong Kong
- Many Locations, India
- Many Locations, Indonesia
- (and 8 more...)
|
| 44 |
NCT02455102 |
Completed |
Electronic Warning System for Atrial Fibrillation |
|
- Other: Electronic warning alert
|
Interventional |
Not Applicable |
- University Hospital Inselspital, Berne
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Participant)
- Primary Purpose: Prevention
|
- Rate of initiation of adequate measures to prevent stroke (oral anticoagulant prescription) by physician in charge
- Use of the CHA2DS2VASc score calculation tool by the physician in charge
- Rate of correct evaluation of the CHA2DS2VASC Score through the calculation tool by physician in charge
|
1707 |
All |
18 Years and older (Adult, Senior) |
NCT02455102 |
022/14 |
|
September 2014 |
October 2015 |
October 2015 |
May 27, 2015 |
December 22, 2015 |
|
- Swiss Cardiovascular Center, Inselspital, University of Bern
Bern, Switzerland
|
| 45 |
NCT01927445 |
Completed |
Improving Stroke Prevention Therapy for Patients With Atrial Fibrillation in Primary Care |
|
- Other: quality improvement toolkit
|
Interventional |
Not Applicable |
- Sunnybrook Health Sciences Centre
- Heart and Stroke Foundation of Ontario
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Health Services Research
|
- Proportion of patients with AF receiving guideline-concordant stroke prevention therapy
- proportion of patients taking warfarin in therapeutic range
- proportion of patients taking a novel anticoagulant with appropriate dosing
- (and 3 more...)
|
5000 |
All |
18 Years and older (Adult, Senior) |
NCT01927445 |
G-13-0001873 |
|
August 2014 |
April 2017 |
June 2017 |
August 22, 2013 |
October 5, 2017 |
|
- Institute for Clinical Evaluative Sciences
Toronto, Ontario, Canada
|
| 46 |
NCT01944397 |
Unknown † |
A CALIBER Study: Risk Factors for Stroke, Heart Failure, and Myocardial Infarction in Atrial Fibrillation |
- Atrial Fibrillation
- Heart Failure
- Stroke
- Myocardial Infarction
|
|
Observational |
|
- University College, London
- London School of Hygiene and Tropical Medicine
- St Bartholomews and The Royal London Hospital
|
Other |
- Observational Model: Cohort
- Time Perspective: Retrospective
|
- Stroke (ischaemic, haemorrhagic, and NOS)
- Myocardial infarction
- Heart failure
- (and 2 more...)
|
125000 |
All |
30 Years and older (Adult, Senior) |
NCT01944397 |
CALIBER-12-03-PROG-18
086091/Z/08/Z
RP-PG-0407-10314
G0902393 |
|
December 2011 |
December 2013 |
December 2014 |
September 17, 2013 |
September 17, 2013 |
|
- University College London
London, United Kingdom
|
| 47 |
NCT02142413 |
Active, not recruiting |
HEart and BRain Interfaces in Acute Ischemic Stroke |
- Stroke
- Atrial Fibrillation
|
|
Observational |
|
- Charite University, Berlin, Germany
- Center for Stroke Research Berlin
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Stroke aetiology
- Atrial fibrillation
- Stroke localization and cardiac dysfunction
- Outcome
|
368 |
All |
18 Years and older (Adult, Senior) |
NCT02142413 |
EA2/033/14 |
HEBRAS |
May 2014 |
February 2017 |
March 2018 |
May 20, 2014 |
May 16, 2017 |
|
- Charité, University Medicine Berlin
Berlin, Germany
|
| 48 |
NCT03147911 |
Active, not recruiting |
Clinical and Laboratory Predictors Associated With Stroke or Systemic Embolism in Low Risk Atrial Fibrillation Patients |
|
|
Observational |
|
- Korea University Guro Hospital
- Samjin Pharmaceutical Co., Ltd.
|
Other / Industry |
- Observational Model: Cohort
- Time Perspective: Retrospective
|
- The novel risk stratification regarding stroke or systemic embolism in order to discriminate true low-risk patients from low-risk patients based on a CHA2DS2-VASc score.
- The prevalence of patients with a CHA2DS2-VASc score of 0 or 1 among patients who have a AF-related thromboembolism.
|
1181 |
All |
18 Years and older (Adult, Senior) |
NCT03147911 |
KUGH17012 (CLASS-AF) |
CLASS-AF |
April 6, 2017 |
February 20, 2018 |
June 1, 2018 |
May 10, 2017 |
March 7, 2018 |
|
- Korea University Ansan Hospital
Ansan, Korea, Republic of - Pusan National University Hospital
Busan, Korea, Republic of - Kosin University Gospel Hospital
Busan, Korea, Republic of - (and 6 more...)
|
| 49 |
NCT02147444 |
Unknown † |
Evaluation of Effectiveness and Safety of Xa Inhibitor for the Prevention of Stroke And Systemic Embolism in a Nationwide Cohort of Japanese Patients Diagnosed as Non-valvular Atrial Fibrillation |
- Non-valvular Atrial Fibrillation
|
|
Observational |
|
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Combinations of symptomatic stroke (ischemic or hemorrhagic) and systemic embolism
- Clinically significant hemorrhagic events (massive hemorrhage in accordance with the ISTH classification)
- Combinations of symptomatic stroke (ischemic or hemorrhagic), systemic embolism, myocardial infarction and cardiovascular death
- (and 10 more...)
|
7000 |
All |
20 Years and older (Adult, Senior) |
NCT02147444 |
EXPAND study
UMIN000009376 |
EXPAND |
November 2012 |
June 2016 |
|
May 26, 2014 |
May 26, 2014 |
|
- Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine
Sendai, Miyagi, Japan
|
| 50 |
NCT02960880 |
Completed |
Real-world Comparative Effectiveness of Stroke Prevention in Patients With Atrial Fibrillation Treated With Rivaroxaban vs. Vitamin k Antagonists |
|
- Drug: Rivaroxaban (Xarelto, BAY597939)
- Drug: Phenprocoumon (branded and generics)
|
Observational |
|
- Bayer
- Janssen Research & Development, LLC
|
Industry |
- Observational Model: Cohort
- Time Perspective: Retrospective
|
- Risk of ischemic stroke estimated as the number of hospitalizations with the ICD-10-GM diagnosis
- Risk of intracranial hemorrhage (ICH) estimated as the number of hospitalizations with the ICD-10-GM diagnosis
- Risk of ischemic stroke or ICH estimated as the number of hospitalizations with the respective ICD-10-GM diagnosis
- (and 3 more...)
|
99999 |
All |
18 Years and older (Adult, Senior) |
NCT02960880 |
18735 |
|
October 15, 2016 |
December 31, 2016 |
December 31, 2016 |
November 10, 2016 |
December 26, 2017 |
|
- Multiple Locations, Germany
|
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