Comment Period Extended to 3/23/2015 for Notice of Proposed Rulemaking (NPRM) for FDAAA 801 and NIH Draft Reporting Policy for NIH-Funded Trials
647 studies found for:    Alexander Disease
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Rank Status Study
1 Recruiting Cardiopulmonary Rehabilitation for Adolescents and Adults With Congenital Heart Disease
Conditions: Congenital Heart Disease;   Heart Defects, Congenital
Interventions: Other: Cardiopulmonary rehabilitation;   Other: Standard of care
2 Recruiting Autologous Bone Marrow Mononuclear Cells in the Combined Treatment of Coronary Heart Disease
Condition: Ischemic Heart Disease
Intervention: Procedure: coronary artery bypass grafting with administration of autologous bone marrow stem cells
3 Recruiting Observational Study of the Genetic Architecture of Neutrophil-Mediated Inflammatory Skin Diseases
Conditions: Other Specified Inflammatory Disorders of Skin or Subcutaneous Tissue;   Pyoderma Gangrenosum;   Erosive Pustular Dermatosis of the Scalp;   Sweet's Syndrome;   Behcet's Disease;   Bowel-associated Dermatosis-arthritis Syndrome;   Pustular Psoriasis;   Acute Generalized Exanthematous Pustulosis;   Keratoderma Blenorrhagicum;   Sneddon-Wilkinson Disease;   IgA Pemphigus;   Amicrobial Pustulosis of the Folds;   Infantile Acropustulosis;   Transient Neonatal Pustulosis;   Neutrophilic Eccrine Hidradenitis;   Rheumatoid Neutrophilic Dermatitis;   Neutrophilic Urticaria;   Still's Disease;   Erythema Marginatum;   Unclassified Periodic Fever Syndromes / Autoinflammatory Syndromes;   Dermatitis Herpetiformis;   Linear IgA Bullous Dermatosis;   Bullous Systemic Lupus Erythematosus;   Inflammatory Epidermolysis Bullosa Aquisita;   Neutrophilic Dermatosis of the Dorsal Hands (Pustular Vasculitis);   Small Vessel Vasculitis Including Urticarial Vasculitis;   Erythema Elevatum Diutinum;   Medium Vessel Vasculitis
Intervention: Procedure: Collection of biological samples
4 Recruiting Stability and Balance in Locomotion Through Exercise
Condition: Parkinson's Disease
Interventions: Behavioral: treadmill walking;   Device: Treadmill
5 Recruiting Pharmacologically Active Constituents of Chocolate and Their Symptomatic Effects in Patients With Idiopathic Parkinson's Disease
Condition: Parkinson Disease
Interventions: Dietary Supplement: Dark chocolate (85% cocoa);   Dietary Supplement: White chocolate (0% cocoa)
6 Unknown  Effects of Chocolate on Motor Symptoms of Parkinson's Disease
Condition: Parkinson's Disease
Intervention: Dietary Supplement: Chocolate
7 Recruiting Kappa Opioid Receptor Imaging in Post-traumatic Stress Disorder (PTSD)
Conditions: Post-traumatic Stress Disorder (PTSD);   Trauma
Intervention: Other: Positron emission tomography (PET) imaging
8 Recruiting Lisdexamfetamine Dimesylate in Residual Symptoms and Cognitive Impairment in Major Depressive Disorder.
Condition: Major Depressive Disorder
Intervention: Drug: Lisdexamfetamine Dimesylate  20-50 mg
9 Recruiting Home Therapy With VPRIV in Gaucher's Disease
Condition: Gaucher's Disease
Intervention:
10 Recruiting Deep Brain Stimulation (DBS) for the Treatment of Parkinson's Disease
Condition: Parkinson's Disease
Intervention: Device: Deep Brain Stimulation
11 Recruiting SAD/MAD Study to Assess Safety, Tolerability, PK & PD of MEDI1814 in Subjects With Mild-Moderate Alzheimer's Disease
Conditions: Mild-Moderate Alzheimer's Disease;   Healthy Elderly
Interventions: Biological: MEDI1814 for IV injection;   Biological: MEDI1814 for Subcutaneous Injection;   Biological: IV Placebo;   Biological: Placebo for Subcutaneous Injection
12 Not yet recruiting Meditation and Stretching for Post Treatment Lyme Disease Syndrome
Condition: Post Treatment Lyme Disease Syndrome
Intervention: Behavioral: Kundalini Yoga
13 Recruiting CB1 Receptor PET Imaging Reveals Gender Differences in PTSD
Condition: Post-traumatic Stress Disorder (PTSD)
Intervention: Other: Positron emission tomography (PET) imaging
14 Recruiting A mGlu2/3 Agonist in the Treatment of PTSD
Condition: Post-traumatic Stress Disorder
Interventions: Drug: Pomaglumetad Methionil 160mg;   Drug: Pomaglumetad Methionil 40mg;   Drug: Placebo
15 Recruiting Removal of Cytokines During Extracorporeal Circulation in Cardiac Surgery
Conditions: Coronary Artery Disease;   Heart Valve Diseases
Intervention: Device: CytoSorb device
16 Recruiting Ticagrelor Antiplatelet Therapy to Reduce Graft Events and Thrombosis
Condition: Saphenous Vein Graft Disease
Interventions: Drug: Aspirin;   Drug: Ticagrelor
17 Recruiting CASA: Care and Support Access in HIV Disease
Condition: HIV/AIDS
Intervention: Other: CASA Education
18 Terminated Clopidogrel and the Optimization of Gastrointestinal Events (COGENT-1)
Conditions: Acute Coronary Syndrome;   Myocardial Infarction;   Coronary Artery Disease;   Percutaneous Coronary Intervention
Interventions: Drug: CGT-2168 (clopidogrel 75 mg/omeprazole 20 mg) and aspirin;   Drug: Plavix (clopidogrel 75 mg) and aspirin
19 Completed Phase II Study With CC-10004 in Psoriatic Arthritis
Condition: Psoriatic Arthritis
Interventions: Drug: CC-10004;   Drug: Matching Placebo
20 Recruiting Executive Functioning in TBI From Rehabilitation to Social Reintegration: COMPASS
Conditions: Traumatic Brain Injury;   Post-Traumatic Stress Disorder
Interventions: Behavioral: Experimental - COMPASS;   Behavioral: Control - COMPASS

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