Comment Period Extended to 3/23/2015 for Notice of Proposed Rulemaking (NPRM) for FDAAA 801 and NIH Draft Reporting Policy for NIH-Funded Trials
648 studies found for:    Alexander Disease
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Rank Status Study
21 Recruiting Kappa Opioid Receptor Imaging in Depression (KOR Depression)
Conditions: Major Depressive Disorder;   Anhedonia
Intervention: Other: Positron Emission Tomography (PET) imaging
22 Recruiting Levetiracetam for Alzheimer's Disease-Associated Epileptiform Activity
Condition: Early-onset Alzheimer's Disease
Intervention: Drug: levetiracetam
23 Completed
Has Results
A Study to Evaluate MEDI-524 In Children With Hemodynamically Significant Congenital Heart Disease
Condition: Congenital Heart Disease
Interventions: Biological: Motavizumab;   Biological: Palivizumab
24 Active, not recruiting A Study Comparing Cardiovascular Effects of Ticagrelor and Clopidogrel in Patients With Peripheral Artery Disease
Condition: Peripheral Artery Disease
Interventions: Drug: Ticagrelor;   Drug: Clopidogrel
25 Recruiting A Study to Evaluate the Effect of Long-term Treatment With BELVIQ (Lorcaserin HCl) on the Incidence of Major Adverse Cardiovascular Events and Conversion to Type 2 Diabetes Mellitus in Obese and Overweight Subjects With Cardiovascular Disease or Multiple Cardiovascular Risk Factors
Conditions: Cardiovascular Disease;   High Cardiovascular Risk;   Obesity;   Overweight;   Type 2 Diabetes
Interventions: Drug: APD356-Lorcaserin hydrochloride;   Drug: Placebo
26 Withdrawn Study of the Safety and Effectiveness of Rilonacept (IL-1 Trap) Administered Subcutaneously in Subjects With Non Dialysis-Dependent Chronic Kidney Disease (NDD-CKD) and Anemia
Conditions: Chronic Kidney Disease;   Anemia
Intervention: Drug: Rilonacept
27 Completed Behavioral Activation for Posttraumatic Stress Disorder (PTSD)/ Depression Treatment in Operations Iraqi Freedom and Enduring Freedom (OIF/OEF) Veterans
Conditions: Posttraumatic Stress Disorder;   Depression
Interventions: Behavioral: Behavioral Activation treatment;   Other: Usual VA Treatment for PTSD
28 Not yet recruiting Group Versus Internet-based Cognitive Behavior Therapy for Procrastination
Condition: Procrastination
Interventions: Behavioral: Cognitive behavior group therapy;   Behavioral: Internet-based cognitive behavior therapy
29 Terminated
Has Results
SPD489 Adult Major Depressive Disorder (MDD) Open-label Safety and Tolerability Rollover Extension Study
Condition: Major Depressive Disorder
Intervention: Drug: SPD489 (Lisdexamfetamine dimesylate) + Antidepressant
30 Recruiting An Efficacy and Safety Study of AZD3293 in Early Alzheimer's Disease
Condition: Alzheimer´s Disease
Interventions: Drug: AZD3293;   Drug: Placebo
31 Recruiting Randomized, Placebo Controlled Study Of The Efficacy And Safety Of PF-02545920 In Subjects With Huntington's Disease
Condition: Huntington's Disease
Interventions: Drug: PF-02545920;   Other: Placebo
32 Completed
Has Results
Efficacy and Safety Study of SPD489 in Combination With an Antidepressant in the Treatment of Adults With Major Depressive Disorder
Condition: Major Depressive Disorder
Interventions: Drug: Antidepressant + SPD489 (Lisdexamfetamine dimesylate );   Drug: Antidepressant + Placebo
33 Terminated Safety and Efficacy Study of PB127 Ultrasound Contrast Agent for Diagnosis of Coronary Artery Disease
Condition: Coronary Artery Disease
Intervention: Drug: PB127 for Injectable Suspension
34 Unknown  Psychological Effects of Tai Chi Training
Condition: Attention Deficit Disorder With Hyperactivity
Intervention: Behavioral: Tai Chi training
35 Unknown  Effects of Paliperidone in Posttraumatic Stress Disorder (PTSD)
Condition: Posttraumatic Stress Disorder
Intervention: Drug: Paliperidone
36 Recruiting A Pilot Treatment Study of Insulin-Like Growth Factor-1 (IGF-1) in Autism Spectrum Disorder
Condition: Autism Spectrum Disorder
Interventions: Drug: IGF-1;   Drug: Placebo/saline
37 Terminated
Has Results
One-Year Trial of Oral Ziprasidone in Bipolar Patients With Metabolic Syndrome
Condition: Bipolar Disorder
Intervention: Drug: Ziprasidone HCL (oral)
38 Unknown  A Study for Small Cell Lung Cancer (SCLC) in Extensive Disease Stage
Condition: Small Cell Lung Cancer
Intervention: Drug: Carboplatin plus Irinotecan vs Carboplatin plus Etoposide
39 Completed Randomized Study Comparing Genz-644470, Placebo, and Sevelamer Carbonate in Chronic Kidney Disease Patients on Hemodialysis
Condition: Kidney Failure, Chronic
Interventions: Drug: Genz-644470;   Drug: Placebo;   Drug: Sevelamer carbonate, Renvela
40 Recruiting Study Evaluating TheSafety And Efficacy Of PF-05212377 Or Placebo In Subjects With Alzheimer's Disease With Existing Neuropsychiatric Symptoms On Donepezil
Condition: Alzheimer's Disease
Interventions: Drug: PF-05212377 (SAM-760);   Other: Placebo

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Indicates status has not been verified in more than two years