| 1 |
NCT01304576 |
Completed |
Orientation Agnosia: Clinical and Anatomical Study |
- Cerebrovascular Disorders
- Brain Lesions
|
- Behavioral: Neuropsychological testing
- Other: MRI
|
Interventional
|
Not Applicable |
- University Hospital, Rouen
|
Other |
- Allocation: Non-Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Screening
|
- orientation agnosia evaluation
- associated clinical symptoms especially apraxia
|
34 |
All |
18 Years to 80 Years (Adult, Older Adult) |
NCT01304576 |
2009/126/HP
number ID RCB 2009-A01005-52 |
AGNORIENT |
September 2010 |
December 2013 |
December 2013 |
February 25, 2011 |
September 3, 2014 |
|
- CHU de Rouen - Hôpitaux de Rouen
Rouen, Haute-Normandie, France
|
|
| 2 |
NCT03482947 |
Recruiting |
TAP vs Caudal Block Using Dexmedetomidine/ Bupivacaine for Post Operative Analgesia |
|
- Drug: ultrasonography-guided TAP block
- Drug: Caudal epidural block
|
Interventional
|
Not Applicable |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Triple (Participant, Care Provider, Investigator)
- Primary Purpose: Prevention
|
- Postoperative pain
- Postoperative analgesia
|
80 |
All |
2 Years to 8 Years (Child) |
NCT03482947 |
TAP/ECB |
|
April 1, 2018 |
October 1, 2018 |
November 1, 2018 |
March 29, 2018 |
May 4, 2018 |
|
- Assiut governorate
Assiut, Egypt
|
|
| 3 |
NCT03389789 |
Completed |
Newborn Cortical Response to Pain and Non Pharmacological Analgesia |
|
- Other: Oral glucose solution + maternal holding
- Other: Breastfeeding
- Other: Oral glucose solution
- Other: Oral expressed breastmilk
|
Interventional
|
Not Applicable |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Supportive Care
|
- Cortical oxy-haemoglobin increase
- Neonatal Infant Pain Scale (NIPS)
|
80 |
All |
up to 3 Days (Child) |
NCT03389789 |
RC 50/11 |
|
November 2, 2016 |
May 31, 2017 |
May 31, 2017 |
January 4, 2018 |
January 5, 2018 |
|
|
|
| 4 |
NCT03258879 |
Not yet recruiting |
Comparison of Labor Analgesia Between Modified Combined Spinal-Epidural and Dural Puncture Epidural Techniques |
- To Determine the Onset of Analgesia (Numerical Rating Scale for Pain = 1) in Minutes
|
- Procedure: Modified CSE
- Procedure: Dural puncture epidural
|
Interventional
|
Not Applicable |
- Western University, Canada
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Triple (Participant, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Comparison of the onset of effective analgesia between the study techniques
- Comparison of block quality between the study techniques
- Comparison of the incidence of pruritus between the study techniques
- Comparison of the incidence of fetal bradycardia between the study techniques
|
80 |
Female |
18 Years to 40 Years (Adult) |
NCT03258879 |
10017388 |
|
January 2018 |
August 2018 |
August 2018 |
August 23, 2017 |
November 14, 2017 |
|
|
|
| 5 |
NCT03221491 |
Completed |
Comparison of Patient-Controlled Analgesia With Different Background Infusion |
- Patient-Controlled Analgesia
|
- Device: Patient-Controlled Analgesia(PCA)
|
Interventional
|
Not Applicable |
- Weifeng Tu
- Guangzhou General Hospital of Guangzhou Military Command
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Participant, Outcomes Assessor)
- Primary Purpose: Health Services Research
|
- Dezocine consumption by patient-controlled analgesia
- The incidence rates of postoperative nausea and vomiting (PONV)
- Change in ramsay sedation score
- Change in pain score
|
90 |
All |
18 Years to 65 Years (Adult, Older Adult) |
NCT03221491 |
Different Background Infusion |
|
July 1, 2016 |
June 30, 2017 |
June 30, 2017 |
July 18, 2017 |
July 21, 2017 |
|
- Guangzhou General Hospital of Guangzhou Military Command
Guangzhou, Guangdong, China
|
|
| 6 |
NCT03203967 |
Completed |
Epidural Morphine for Postoperative Analgesia After Total Knee Arthroplasty |
- Adult Patients
- Total Knee Arthroplasty
- Epidural Analgesia
- (and 2 more...)
|
- Procedure: Epidural morphine
- Procedure: Epidural placebo
- Procedure: Single femoral nerve block
- Drug: Intravenous morphine analgesia
|
Interventional
|
Not Applicable |
- Peking University First Hospital
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Supportive Care
|
- Percent of patients with moderate to severe pain (Numeric Rating Scale pain score of 4 or higher)
- NRS pain scores (at rest and with movement) at various timepoints after surgery
- Cumulative morphine consumption
- (and 7 more...)
|
110 |
All |
18 Years to 90 Years (Adult, Older Adult) |
NCT03203967 |
2017[1308] |
|
July 1, 2017 |
April 30, 2018 |
May 30, 2018 |
June 29, 2017 |
June 4, 2018 |
|
- Peking University First Hospital
Beijing, Beijing, China
|
|
| 7 |
NCT03170726 |
Active, not recruiting |
Impact of Preemptive Intravenous Ibuprofen on Intraoperative Analgesia in Third Molar Teeth |
- Preemptive Intravenous Ibuprofen
- Intraoperative Analgesia
|
- Drug: arveles
- Drug: intrafen 800 mg
- Other: plasebos
|
Interventional
|
Not Applicable |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Participant, Investigator)
- Primary Purpose: Treatment
|
- intraoperative pain as assessed by visual analogue scale
- postoperative pain as assessed by visual analogue scale
|
60 |
All |
20 Years to 35 Years (Adult) |
NCT03170726 |
ERZINCAN UNIVERSITY 9 |
|
May 15, 2017 |
October 30, 2017 |
November 15, 2017 |
May 31, 2017 |
May 31, 2017 |
|
- Erzincan University
Erzincan, Turkey
|
|
| 8 |
NCT03126136 |
Not yet recruiting |
Pulse Pressure Variability With Position Before EPIdural Analgesia |
|
|
Interventional
|
Not Applicable |
|
Other |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Diagnostic
|
- Fetal heart rate
- Mode of delivery
- Newborn heart rate, blood pressure, pulse pressure, and cardiac output
- Number of patients with hemodynamic abnormalities
|
900 |
Female |
18 Years and older (Adult, Older Adult) |
NCT03126136 |
2016/31
2016- A00846-45 |
PP-PERI |
November 2017 |
November 2019 |
November 2019 |
April 24, 2017 |
October 12, 2017 |
|
- AP-HP Hopital Antoine Beclere
Clamart, France - Institut Hospitalier Franco-Britannique
Levallois-Perret, France - Institut Mutualiste Montsouris
Paris, France - Hopital Foch
Suresnes, France
|
|
| 9 |
NCT03107559 |
Recruiting |
Perfusion Index and Labor Analgesia |
- perfüsion Index in Removal of the Epidural Analgesia
|
- Diagnostic Test: perfüsion index
|
Observational
|
|
|
Other |
- Observational Model: Case-Control
- Time Perspective: Prospective
|
- relationship between Visual analogue scale and Perfüsion index
- relationship between heart rate and Perfüsion index
- relationship between non-invazive blood pressure and Perfüsion index
|
30 |
Female |
18 Years to 45 Years (Adult) |
NCT03107559 |
ERZINCAN UNIVERSITY pain&pi |
|
May 30, 2017 |
July 15, 2017 |
August 1, 2017 |
April 11, 2017 |
May 23, 2017 |
|
- Erzincan University
Erzincan, Turkey
|
|
| 10 |
NCT03105193 |
Not yet recruiting |
Intravenous and Intraperitoneal Lignocaine for Perioperative Analgesia in Laparoscopic Colon Resections |
- Laparoscopic Colon Resection
- Perioperative Analgesia
|
- Drug: IV Saline bolus and infusion
- Drug: IP Saline bolus and infusion
- Drug: IV lignocaine bolus and infusion
- Drug: IP Lignocaine bolus and infusion
|
Interventional
|
Phase 4 |
- University of Auckland, New Zealand
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Morphine consumption
- Pain scores
- Systemic Inflammatory Response (CRP and WBC)
- (and 5 more...)
|
60 |
All |
16 Years and older (Child, Adult, Older Adult) |
NCT03105193 |
IPL/IVL |
|
December 1, 2017 |
December 1, 2018 |
December 30, 2018 |
April 7, 2017 |
October 31, 2017 |
|
|
|
| 11 |
NCT03060265 |
Not yet recruiting |
Protective Analgesia in Caesarean Section Using Intravenous Paracetamol |
|
- Drug: Paracetamol
- Drug: PLACEBO
|
Interventional
|
Not Applicable |
|
Other |
- Allocation: Randomized
- Intervention Model: Crossover Assignment
- Masking: Triple (Participant, Care Provider, Investigator)
- Primary Purpose: Prevention
|
- The pain intensity level
- side effects
- Postoperative time to administration of first analgesic dose (Time-to-Analgesia; TTA).
- Number of analgesic doses administered in the first 24 hours after surgery.
|
60 |
Female |
18 Years to 40 Years (Adult) |
NCT03060265 |
BnaiZionMC-16-MS-003 |
|
March 2017 |
June 2017 |
December 2017 |
February 23, 2017 |
February 23, 2017 |
|
|
|
| 12 |
NCT03014713 |
Recruiting |
Effect of Dexmedetomidine for Postoperative Intravenous Patient Controlled Analgesia |
- Patient-Controlled Analgesia
|
- Drug: Dezocine
- Drug: Flubiprofen
- Drug: Dexmedetomidine
|
Interventional
|
Phase 4 |
- Weifeng Tu
- Guangzhou General Hospital of Guangzhou Military Command
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Participant, Outcomes Assessor)
- Primary Purpose: Health Services Research
|
- Dezocine consumption by patient-controlled analgesia
- Change in pain score
- Change in ramsay sedation score
- The incidence rates of postoperative nausea and vomiting (PONV)
|
50 |
All |
18 Years to 65 Years (Adult, Older Adult) |
NCT03014713 |
Dexmedetomidine PCA |
|
September 2016 |
December 2017 |
December 2017 |
January 9, 2017 |
January 9, 2017 |
|
- Guangzhou General Hospital of Guangzhou Military Command
Guangzhou, Guangdong, China
|
|
| 13 |
NCT03012971 |
Recruiting |
Dexmedetomidine Supplemented Analgesia and 3-Year Survival After Cancer Surgery |
- Elderly
- Surgery
- Analgesia
- (and 2 more...)
|
- Drug: Dexmedetomidine supplemented morphine analgesia
- Drug: Morphine analgesia
|
Interventional
|
Phase 4 |
- Peking University First Hospital
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Prevention
|
- 3-year overall survival after surgery
- Survival rates at different time-points after surgery
- Duration of recurrence-free survival after surgery
- (and 2 more...)
|
1200 |
All |
65 Years to 90 Years (Older Adult) |
NCT03012971 |
DEXanalgesiaLT |
|
January 2017 |
December 2023 |
December 2024 |
January 6, 2017 |
February 26, 2018 |
|
- Peking University First Hospital
Beijing, Beijing, China
|
|
| 14 |
NCT03007121 |
Not yet recruiting |
Intrathecal Morphine Analgesia vs. Continuous Epidural Analgesia vs. Systemic Analgesia in Colorectal Surgery. |
- Analgesia, Patient-Controlled
- Epidural Analgesia
- Anesthesia; Spinal
- (and 3 more...)
|
- Drug: Morphine intrathecal
- Drug: Bupivacaine + Sufentanil epidural
- Drug: Morphine intravenous
|
Interventional
|
Phase 4 |
- Charles University, Czech Republic
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Non-inferiority of analgesia with intrathecal morphine 0.3mg compared with epidural mixture bupivacaine 0.125% and sufentanil 0,4ug/ml.
- Better analgesia after intrathecal morphine compared to systemic analgesia with morphine
- Side effects of intrathecal morphine compared to epidural or systemic analgesia
- Pain intensity
|
75 |
All |
18 Years and older (Adult, Older Adult) |
NCT03007121 |
KOLORIT1 |
KOLORIT |
January 2017 |
December 2018 |
December 2018 |
January 2, 2017 |
January 4, 2017 |
|
|
|
| 15 |
NCT02990910 |
Completed
Has Results |
Individualized Analgesia on Respiratory Adverse Events After Adenotonsillectomy |
|
- Drug: personalized opioid analgesia
- Device: conventional opioid analgesia
|
Interventional
|
Not Applicable |
- Children's Hospital of Fudan University
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Prevention
|
- Number of Participants With Respiratory Adverse Events in PACU(Postanesthesia Care Unit).
- Median Survival Time of CHEOPS> 6 in the Two Groups.
|
280 |
All |
3 Years to 10 Years (Child) |
NCT02990910 |
IARA |
|
November 2016 |
February 2017 |
February 2017 |
December 13, 2016 |
September 7, 2017 |
August 9, 2017 |
- Chilren's Hospital of Fudan University
Shanghai, Shanghai, China
|
|
| 16 |
NCT02990364 |
Completed |
Combination Analgesia for Neonatal Circumcision |
|
- Drug: Sucrose
- Drug: Lidocaine
- Drug: EMLA Topical Product
|
Interventional
|
Phase 3 |
- American University of Beirut Medical Center
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Participant, Investigator)
- Primary Purpose: Supportive Care
|
- The Neonatal Infant Pain Scale (NIPS)
- Heart Rate
- Crying Time
- Oxygen Saturation
|
70 |
Male |
up to 3 Days (Child) |
NCT02990364 |
SUR.YE.01 |
|
December 2015 |
December 2016 |
January 2017 |
December 13, 2016 |
June 29, 2017 |
|
|
|
| 17 |
NCT02811991 |
Unknown † |
A PhaseⅡ/ Ⅲ Seamless Study to Evaluate Efficacy and Safety of Paracetamol Injection as Adjuvant to Morphine-based Postoperative Analgesia |
|
- Drug: Paracetamol injection
- Drug: Normal Saline injection
- Drug: Morhpine PCA
|
Interventional
|
Phase 2
Phase 3 |
- Jiangsu HengRui Medicine Co., Ltd.
|
Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Total morphine use in 24 hours
- Pain Intensity VAS AUC(0-24h) at rest
- Pain Intensity VAS AUC(0-24h) at movement
- Incidence of mophine-related ADR
|
348 |
All |
18 Years to 70 Years (Adult, Older Adult) |
NCT02811991 |
HR-DYXAJF-Ⅲ |
|
June 2016 |
December 2017 |
March 2018 |
June 23, 2016 |
June 27, 2016 |
|
- Beijing Chao-Yang Hospital
Beijing, Beijing, China - Beijing Friendship Hospital
Beijing, Beijing, China - Beijing Hospital
Beijing, Beijing, China - (and 13 more...)
|
|
| 18 |
NCT02523235 |
Completed |
Effects of Catheter Location on Postoperative Analgesia for Continuous Adductor Canal and Popliteal-Sciatic Nerve Blocks |
- Post-surgical Pain
- Total Knee Arthroplasty
- Foot/Ankle Surgery
- Catheterization for Postop Analgesia
|
|
Interventional
|
Phase 4 |
- University of California, San Diego
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Participant)
- Primary Purpose: Treatment
|
- Pain (average): Numeric Rating Scale for Pain
- Pain (worst) :Numeric Rating Scale for Pain
- Analgesic use: IV morphine equivalents
- (and 6 more...)
|
117 |
All |
18 Years and older (Adult, Older Adult) |
NCT02523235 |
Prox-Distal Catheter Insertion |
|
August 2015 |
February 2018 |
March 2018 |
August 14, 2015 |
March 12, 2018 |
|
- University California San Diego
San Diego, California, United States
|
|
| 19 |
NCT02264821 |
Completed
Has Results |
Wound Infusion vs Spinal Morphine for Post-caesarean Analgesia |
|
- Drug: ropivacaine infiltration
- Drug: intrathecal morphine
- Drug: placebo
|
Interventional
|
Phase 3 |
- Dr Madeleine Wilwerth
- Brugmann University Hospital
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Triple (Participant, Care Provider, Investigator)
- Primary Purpose: Treatment
|
- Duration of Effective Analgesia
- Morphine Consumption
- Incidence of Morphine Side Effects: Nausea, Vomiting, Pruritus.
|
192 |
Female |
18 Years and older (Adult, Older Adult) |
NCT02264821 |
Apcisaal 01 |
Apcisaal |
February 2012 |
August 2014 |
August 2014 |
October 15, 2014 |
June 9, 2015 |
June 9, 2015 |
- Centre Hospitalier Universitaire Brugmann
Bruxelles, Belgium
|
|
| 20 |
NCT02104934 |
Completed |
A Randomised Controlled Trial Comparing Single Shot Adductor Canal Block With Local Infiltration Analgesia for Postoperative Analgesia After Total Knee Arthroplasty |
- Analgesia in Total Knee Arthroplasty
|
- Procedure: Adductor Canal Block
|
Interventional
|
Not Applicable |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Participant, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Morphine consumption in the first 24 hours
- Pain Scores
- Morphine Consumption
- (and 3 more...)
|
40 |
All |
45 Years to 85 Years (Adult, Older Adult) |
NCT02104934 |
CGHLIAACB2013 |
|
March 2014 |
December 2015 |
March 2016 |
April 7, 2014 |
April 25, 2017 |
|
- Changi General Hospital
Singapore, Singapore
|
|
| 21 |
NCT02099877 |
Completed |
μ-opioid Receptor Polymorphism and Opioid Analgesia |
- Pharmacogenetic and Duration of Labor Fentanyl Analgesia
|
|
Observational
|
|
- American University of Beirut Medical Center
|
Other |
- Observational Model: Other
- Time Perspective: Prospective
|
- Duration of epidural fentanyl
- VAS at request for analgesia
- Cervical dilation at request for analgesia
- Incidence of pruritus, nausea, and vomiting.
|
250 |
Female |
18 Years to 45 Years (Adult) |
NCT02099877 |
ANES.SS.11 |
|
October 2013 |
June 2017 |
June 2017 |
March 31, 2014 |
February 21, 2018 |
|
- American University of Beirut
Beirut, Lebanon
|
|
| 22 |
NCT01886014 |
Completed |
The Effect of Oxytocin on Placebo Analgesia: an Experimental Study in Healthy Volunteers |
- Mechanisms and Modulators of Placebo Analgesia in Healthy Volunteers
|
- Drug: Oxytocin
- Other: placebo
|
Interventional
|
Not Applicable |
- Universitätsklinikum Hamburg-Eppendorf
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Triple (Participant, Investigator, Outcomes Assessor)
- Primary Purpose: Basic Science
|
- Placebo analgesic responses
- pain rating on the control site
|
80 |
Male |
18 Years to 40 Years (Adult) |
NCT01886014 |
placebo_oxy |
|
January 2012 |
September 2012 |
September 2012 |
June 25, 2013 |
June 26, 2013 |
|
- Department of Neurology, University Medical Center Hamburg-Eppendorf
Hamburg, Germany
|
|
| 23 |
NCT01882530 |
Terminated |
Non-opioid Analgesic Combination With Morphine for Postoperative Analgesia. |
|
- Drug: Paracetamol
- Drug: Nefopam
- Drug: Ketoprofen
- Drug: Morphine
|
Interventional
|
Phase 4 |
- Rennes University Hospital
|
Other |
- Allocation: Randomized
- Intervention Model: Factorial Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Morphine consumption (mg), accumulated over 24 hours, measured by patient controlled analgesia (PCA).
- Morphine consumption (mg) measured by patient controlled analgesia (PCA).
- Incidence of side effects associated with morphine: nausea, vomiting, sedation, urinary retention, pruritus.
- (and 3 more...)
|
223 |
All |
18 Years and older (Adult, Older Adult) |
NCT01882530 |
130505A-32 |
OCTOPUS |
July 23, 2013 |
January 16, 2016 |
January 16, 2016 |
June 20, 2013 |
February 6, 2018 |
|
- Karine Nouette-Gaulain
Bordeaux, France - Marcel Chauvin
Boulogne, France - Hawa Keita-Meyer
Colombes, France - (and 16 more...)
|
|
| 24 |
NCT01739270 |
Unknown † |
Dexamethasone Added to Levobupivacaine Improves Postoperative Analgesia |
- Brachial Plexus Anesthesia
- Analgesia
|
- Procedure: supraclavicular brachial plexus block
|
Interventional
|
Not Applicable |
- University Hospital Dubrava
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Investigator)
- Primary Purpose: Treatment
|
- duration of analgesia
- postoperative analgesic consumption
|
55 |
All |
18 Years to 80 Years (Adult, Older Adult) |
NCT01739270 |
0911 |
|
October 2012 |
January 2013 |
|
December 3, 2012 |
July 29, 2015 |
|
- Clinical Hospital Dubrava
Zagreb, Croatia
|
|
| 25 |
NCT01553435 |
Unknown † |
Effect of N-methyl D-aspartate (NMDA) Receptor Antagonist Dextromethorphan on Opiods Analgesia and Tolerance in Pediatric Intensive Care Unit Patients |
- Pain
- Opioid Tolerance
- Analgesia Tolerance
|
- Drug: Dextromethorphan
- Drug: Placebo
|
Interventional
|
Not Applicable |
- King Abdullah International Medical Research Center
|
Other |
- Allocation: Randomized
- Intervention Model: Single Group Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Supportive Care
|
- Effect of N-methyl D-aspartate (NMDA) receptor antagonist Dextromethorphan on Opiods analgesia and tolerance in Pediatric Intensive Care Unit Patients
|
36 |
All |
2 Years to 14 Years (Child) |
NCT01553435 |
RC 09-120 |
|
January 2011 |
January 2015 |
|
March 14, 2012 |
April 14, 2015 |
|
- King Abdul Aziz Medical City
Riyadh, Central, Saudi Arabia
|
|
| 26 |
NCT01280084 |
Completed |
Labour Analgesia and Movement in Babies |
- Labour Analgesia and Neonate Activity
|
|
Observational
|
|
- University of British Columbia
|
Other |
- Observational Model: Case Control
- Time Perspective: Prospective
|
- Neonates' mobile and immobile time in 24 hours
- Neonates' number of mobile and immobile bouts in 24 hours
- Total activity score
- (and 2 more...)
|
40 |
Female |
19 Years and older (Adult, Older Adult) |
NCT01280084 |
H10-02900 |
LAMB |
February 2011 |
August 2011 |
August 2011 |
January 20, 2011 |
February 14, 2012 |
|
- British Columbia Women's Hospital
Vancouver, British Columbia, Canada
|
|
| 27 |
NCT01261689 |
Completed |
The Randomised Epidural Analgesia in Term Delivering Women Trial (TREAT) |
- Analgesia, Epidural
- Instrumental Delivery
- Maternal Outcome
- Neonatal Outcome
|
- Drug: Ropivacaine/ Sufentanil according to local hospital protocol
- Other: Care-as usual pain treatment
|
Interventional
|
Not Applicable |
- Maastricht University Medical Center
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Supportive Care
|
- instrumental delivery
- start labour
- Oxytocin use
- (and 18 more...)
|
488 |
Male |
18 Years and older (Adult, Older Adult) |
NCT01261689 |
TREAT01 |
TREAT |
September 2008 |
November 2013 |
November 2013 |
December 16, 2010 |
November 27, 2013 |
|
- Atrium Medical Centre Parkstad
Heerlen, Limburg, Netherlands - Maastricht University Medical Centre
Maastricht, Limburg, Netherlands
|
|
| 28 |
NCT00954317 |
Unknown † |
Do Epidurals Placed at a Lower Level Improve Labor Analgesia? |
|
- Procedure: epidural placed low
- Procedure: high epidural
|
Interventional
|
Not Applicable |
- Royal Victoria Hospital, Canada
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Participant)
- Primary Purpose: Treatment
|
- Number of epidural medication boluses required
- Labour progress
|
100 |
Female |
18 Years and older (Adult, Older Adult) |
NCT00954317 |
SDR-08-052 |
|
September 2009 |
January 2014 |
January 2014 |
August 7, 2009 |
November 30, 2012 |
|
- Royal Victoria Hospital
Montreal, Quebec, Canada
|
|
| 29 |
NCT00800826 |
Completed |
The Combination Effect of Dexmedetomidine and Morphine in Postoperative Patient-Controlled Analgesia |
- Analgesia, Patient-Controlled
- Analgesia, Postoperative
|
|
Interventional
|
Phase 4 |
- National Taiwan University Hospital
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Triple (Participant, Investigator, Outcomes Assessor)
- Primary Purpose: Health Services Research
|
|
150 |
All |
18 Years to 65 Years (Adult, Older Adult) |
NCT00800826 |
950910 |
|
November 2006 |
|
April 2008 |
December 2, 2008 |
December 2, 2008 |
|
|
|
| 30 |
NCT00791024 |
Completed |
Development of a New Method for Analgesia |
|
- Drug: CRC-Pharma 001
- Drug: lidocaine suspension
|
Interventional
|
Phase 1
Phase 2 |
- Ove Andersen
- University of Copenhagen
- Hvidovre University Hospital
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Investigator)
- Primary Purpose: Supportive Care
|
- VAS score
- Questionnaire( examiner and patient)
|
126 |
All |
18 Years to 70 Years (Adult, Older Adult) |
NCT00791024 |
CRC06 |
|
November 2008 |
November 2009 |
January 2010 |
November 14, 2008 |
August 26, 2015 |
|
- Copenhagen University, Hvidovre Hospital
Hvidovre, Denmark
|
|
| 31 |
NCT00762554 |
Unknown † |
Depodur vs Fentanyl Infusion for Post-C/S Analgesia |
|
- Drug: Depodur
- Drug: Fentanyl
|
Interventional
|
Not Applicable |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Treatment
|
- Degree of analgesia (measured on a 10-point scale)
- Frequency of minor side effects, such as pruritis or nausea.
|
300 |
Female |
18 Years to 45 Years (Adult) |
NCT00762554 |
goodman-1 |
|
October 2008 |
June 2009 |
June 2009 |
September 30, 2008 |
September 30, 2008 |
|
- University Hospitals Case Medical Center
Cleveland, Ohio, United States
|
|
| 32 |
NCT00713726 |
Completed |
Tramadol Versus Fentanyl for Post-Operative Analgesia in Newborn Infants |
- Pain
- Neonatal Infections
- Analgesia
|
- Drug: FentanyL
- Drug: Tramadol
|
Interventional
|
Phase 3 |
- Federal University of São Paulo
- Albert B. Sabin Vaccine Institute
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Pain assessment wuth CRIES and NFCS pain scales during the first 72 hours after surgical procedure
- Time between surgical procedure and successful extubation
- Time between surgical procedure and achievement of 100 mL/kg of enteral feeding
|
160 |
All |
up to 28 Days (Child) |
NCT00713726 |
1386/06 |
|
January 2006 |
July 2008 |
July 2008 |
July 11, 2008 |
July 11, 2008 |
|
- Albert Sabin Hospital
Fortaleza, Ceará, Brazil
|
|
| 33 |
NCT00487084 |
Completed
Has Results |
Effect of Timing on Efficacy of Morphine Analgesia After 2-chloroprocaine Anesthesia |
|
- Drug: Morphine-CP-saline (MCS)
- Drug: saline-2CP-morphine (SCM)
- Drug: saline-lidocaine-morphine (SLM)
|
Interventional
|
Not Applicable |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Participant, Investigator)
- Primary Purpose: Treatment
|
- Duration of Continuing Analgesia
- Supplemental Analgesia in First 90 Minutes
- Verbal Rating Score (0 to 10) for Pain (VRPS)
- Supplemental Analgesia in First 48 Hours
|
136 |
Female |
18 Years to 60 Years (Adult) |
NCT00487084 |
0524-021 |
|
August 2004 |
September 2008 |
September 2008 |
June 15, 2007 |
April 14, 2014 |
April 18, 2011 |
- Northwestern University
Chicago, Illinois, United States
|
|
| 34 |
NCT00436345 |
Terminated
Has Results |
Pharmacoeconomic Consequences Of Analgesia in the Intensive Care Unit (ICU) |
|
- Drug: Remifentanil
- Drug: Propofol
|
Interventional
|
Phase 3 |
|
Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Duration of Time on Mechanical Ventilation (Intent-to-Treat Population)
- Duration of Time on Mechanical Ventilation (Modified-Intent-to-Treat Population)
- Duration of Time on Mechanical Ventilation (Per-Protocol Population)
- (and 22 more...)
|
39 |
All |
18 Years and older (Adult, Older Adult) |
NCT00436345 |
108701 |
|
November 2007 |
August 2008 |
September 2008 |
February 19, 2007 |
May 30, 2017 |
May 18, 2010 |
- GSK Investigational Site
Catanzaro, Calabria, Italy - GSK Investigational Site
Napoli, Campania, Italy - GSK Investigational Site
Ferrara, Emilia-Romagna, Italy - (and 3 more...)
|
|
| 35 |
NCT00421720 |
Terminated |
A Study Comparing Two Analgesia/Sedation Regimens, Remifentanil/Propofol Versus Sufentanil/Propofol In Mechanically Ventilated Intensive Care Patients Requiring Analgesia And Sedation. |
|
- Drug: Sufentanil
- Drug: Remifentanil
|
Interventional
|
Phase 4 |
|
Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Comparison of ventilation and weaning times: - Time from initiation of analgesia/sedation using the investigational substance and extubation ("ventilation time") - Time from the start of weaning to extubation ("weaning time")
- ICU length of stay; accuracy of analgesia/sedation; drug consumption of analgesics/sedatives; clinical course; incidence of pneumonia/delirium; infection markers; bowel movement; ventilation parameters; vital signs; resource utilization; safety
|
164 |
All |
18 Years and older (Adult, Older Adult) |
NCT00421720 |
USA107212
EudraCT: 2006-001276-20 |
|
January 2007 |
|
|
January 12, 2007 |
April 3, 2018 |
|
- GSK Clinical Trials Call Center
Bonn, Germany - GSK Clinical Trials Call Center
Dresden, Germany - GSK Clinical Trials Call Center
Heidelberg, Germany - (and 7 more...)
|
|
| 36 |
NCT00337597 |
Completed |
Continuous Regional Analgesia After Total Knee Arthroplasty |
|
- Other: Glucose 5%
- Other: NaCl 0.9%
|
Interventional
|
Phase 3 |
- Nantes University Hospital
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Participant, Investigator)
- Primary Purpose: Treatment
|
- Characteristics of electrolocation of nerve during insertion of the exploring needle and of the stimulating catheter
- Efficacy of post-operative analgesia
|
50 |
All |
18 Years to 90 Years (Adult, Older Adult) |
NCT00337597 |
BRD 05/7-F |
|
May 2006 |
July 2007 |
December 2007 |
June 16, 2006 |
July 21, 2008 |
|
- Departemental Hospital of la Roche sur Yon
La Roche sur Yon, France - Nantes University Hospital
Nantes, France
|
|
| 37 |
NCT00200564 |
Unknown † |
Ketamine and Postoperative Analgesia in Children |
|
|
Interventional
|
Phase 4 |
- Nantes University Hospital
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single
|
- Area under the curve of pain scores (CHEOPS) measured
- Evaluation by the parents and nurses of the quality of analgesia with a visual analogue scale graded from 0 to 10
- Number of painful episodes requiring additional boluses of nalbuphine
- (and 4 more...)
|
74 |
All |
6 Months to 6 Years (Child) |
NCT00200564 |
BRD/03/12-H |
|
February 2004 |
|
|
September 20, 2005 |
October 23, 2007 |
|
- Nantes University Hospital
Nantes, France
|
|
| 38 |
NCT03240965 |
Recruiting |
Changes in Sensitivity, Taste and Smell in Stroke Patients |
|
- Diagnostic Test: FEES (flexible endoscopic evaluation of swallowing)
- Other: Sensitivity threshold
- Diagnostic Test: Taste-/smell-test
- Diagnostic Test: Neuropsychological testing
|
Observational
|
|
|
Other |
- Observational Model: Case-Only
- Time Perspective: Prospective
|
- Dysphagia
- Neuropsychological deficits
- Lesion site
- (and 2 more...)
|
200 |
All |
18 Years and older (Adult, Older Adult) |
NCT03240965 |
GI-149/16 |
5S |
October 1, 2017 |
December 2019 |
December 2019 |
August 7, 2017 |
October 26, 2017 |
|
- Universitätsklinikum Gießen
Gießen, Hessen, Germany
|
|
| 39 |
NCT03389945 |
Recruiting |
Different Spinal Needles Sizes and Dural Puncture Epidural For Labor Analgesia |
- Labor Pain
- Epidural Analgesia
|
- Procedure: 25G Dural Puncture Epidural Block
- Procedure: 27G Dural Puncture Epidural Block
|
Interventional
|
Not Applicable |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Triple (Participant, Investigator, Outcomes Assessor)
- Primary Purpose: Supportive Care
|
- Time to pain ≤ 1 on NRS (0-10)
- Gestational age
- Obstetric history
- (and 22 more...)
|
140 |
Female |
Child, Adult, Older Adult |
NCT03389945 |
922/17 |
|
January 13, 2018 |
December 31, 2018 |
December 31, 2018 |
January 4, 2018 |
May 1, 2018 |
|
- Hospital Clínico Universidad de Chile
Santiago, Metropolitana, Chile - Hospital La Florida
Santiago, Región Metropolitana, Chile
|
|
| 40 |
NCT03366935 |
Recruiting |
Combined Implementation of Dural Puncture Epidural and Programmed Intermittent Epidural Bolus for Labor Analgesia |
- Labor Pain
- Labor Analgesia
|
- Other: EPL and CEI
- Other: DPE and CEI
- Other: DPE and PIEB
|
Interventional
|
Not Applicable |
- Shanghai First Maternity and Infant Hospital
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Participant, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Compare time of onset of labor analgesia among the study groups
- Incidence of side effect
- Sensory block level
- (and 3 more...)
|
120 |
Female |
20 Years to 40 Years (Adult) |
NCT03366935 |
anesthesia dapartment |
|
October 10, 2017 |
May 1, 2018 |
October 10, 2018 |
December 8, 2017 |
December 19, 2017 |
|
- Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine
Shanghai, China
|
|
| 41 |
NCT03314571 |
Not yet recruiting |
Obstetrical Analgesia in the Estaing Hospital Maternity. A Prospective Database to Study the Determinants of Labor Pain and the Resulting Maternal Non Satisfaction. |
- Epidural Analgesia
- Hospital Follow-up
|
- Other: analgesia for labor
|
Observational
|
|
- University Hospital, Clermont-Ferrand
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Maternal satisfaction about analgesia for labor
- Wish for a similar analgesia for future labor.
- Qualitative maternal concerns about analgesia for labor
|
600 |
Female |
18 Years and older (Adult, Older Adult) |
NCT03314571 |
CHU-357
2017-A00814-49 |
AOMHE |
November 2017 |
December 31, 2020 |
December 31, 2020 |
October 19, 2017 |
November 9, 2017 |
|
- CHU Clermont-Ferrand
Clermont-Ferrand, France
|
|
| 42 |
NCT02920489 |
Completed |
Individualized Timing of Analgesia and Effectiveness of Labor Analgesia |
- Labor Pain
- Analgesia, Obstetrical
- Early Medical Intervention
|
- Drug: Individualized epidural analgesia
- Drug: Routine epidural analgesia
|
Interventional
|
Not Applicable |
- Peking University First Hospital
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Prevention
|
- The most severe labor pain score during labor
- Incidence of instrumental delivery
- Incidence of Cesarean delivery
- (and 5 more...)
|
200 |
Female |
18 Years to 36 Years (Adult) |
NCT02920489 |
2016[1094]
ChiCTR-IPR-16007976 |
|
August 2016 |
June 2017 |
July 2017 |
September 30, 2016 |
July 19, 2017 |
|
- Peking University First Hospital
Beijing, Beijing, China
|
|
| 43 |
NCT02516059 |
Completed |
Early Postoperative Administration of Oxycodone +/- Naloxone and Duration of Epidural Analgesia |
- Postoperative Pain Management
- Radical Cystectomy
- Epidural Analgesia
- (and 2 more...)
|
- Drug: oxycodone/naloxone
- Drug: Oxycodone
- Drug: Placebo
- Device: epidural catheter
|
Interventional
|
Phase 4 |
- University Hospital Inselspital, Berne
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Length of stay of the epidural catheter in days
- Pain scores (NRS 0-10) at postoperative day (POD) 1 to POD 7
- Duration of the return of the bowel function in days
|
90 |
All |
18 Years and older (Adult, Older Adult) |
NCT02516059 |
068/15
WUPD 01-14
2015DR4112 |
|
September 14, 2015 |
February 20, 2017 |
February 28, 2017 |
August 5, 2015 |
March 7, 2017 |
|
- Dep of Urology Bern University Hospital
Bern, Switzerland
|
|
| 44 |
NCT01966172 |
Completed |
Multimodal Analgesic Treatment Versus Traditional Morphine Analgesia After Cardiac Surgery |
- Analgesia
- Postoperative Pain
|
- Drug: Ibuprofen
- Drug: Gabapentin
- Drug: Morphine
- Drug: Paracetamol
|
Interventional
|
Phase 4 |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Treatment
|
- Evaluation of analgesic effect by 11-NRS scale
- Additional analgesic consumption
- Hospital stay in days.
- (and 4 more...)
|
180 |
All |
18 Years and older (Adult, Older Adult) |
NCT01966172 |
Smerte1 |
|
March 2007 |
August 2009 |
December 2009 |
October 21, 2013 |
October 21, 2013 |
|
- Rigshospitalet, Copenhagen University Hospital
Copenhagen, Denmark
|
|
| 45 |
NCT01437358 |
Completed |
Epidural Analgesia in Intensive Care Unit (APD-REA: Analgesie PeriDurale en REAnimation) |
- Critical Illness
- Epidural Analgesia
|
- Other: Epidural analgesia
|
Observational
|
|
- University Hospital, Clermont-Ferrand
|
Other |
- Time Perspective: Cross-Sectional
|
- Incidence of epidural analgesia-related complications
|
80 |
All |
18 Years to 95 Years (Adult, Older Adult) |
NCT01437358 |
CHU-0100 |
|
August 2011 |
December 2011 |
January 2012 |
September 20, 2011 |
February 28, 2012 |
|
- CHU Clermont-Ferrand
Clermont-Ferrand, France
|
|
| 46 |
NCT02561715 |
Recruiting |
Lack of Awareness of Symptoms (Anosognosia) in PD: An Observational Study for People With Parkinson's |
|
- Behavioral: Questionnaires
|
Observational
|
|
|
Other |
- Observational Model: Case-Only
- Time Perspective: Prospective
|
- Improvement of ability to recall extent of condition
- Clinician's Rating Scale for Evaluating Impaired Self Awareness and Denial of Disability after Brain Injury adapted for use with PD patients.after Brain Injury, adapted for use with Parkinson's Disease patients
- Patient Generated Index
- (and 7 more...)
|
20 |
All |
18 Years and older (Adult, Older Adult) |
NCT02561715 |
RG_14-096 |
|
August 2015 |
May 2018 |
November 2018 |
September 28, 2015 |
October 25, 2016 |
|
- Queen Elizabeth Hospital
Birmingham, United Kingdom
|
|
| 47 |
NCT01220362 |
Completed |
Effects of Thoracic Epidural Analgesia and Surgery on Lower Urinary Tract Function: A Randomized, Controlled Study |
- Analgesia, Epidural
- Urodynamics
- Urinary Retention
|
- Drug: Bupivacain 0.125%
- Drug: Bupivacain 0.125%/Fentanyl 2mcg/ml
|
Interventional
|
Not Applicable |
- University Hospital Inselspital, Berne
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Participant, Investigator)
|
- Difference in post-void residual between bupivacaine (group 1) and bupivacaine-fentanyl (group 2) after surgery on day 2 or 3, depending on patient mobilisation.
- Difference in post-void residual before and after surgery under segmental blockade.
- Difference in secondary outcomes (see 2.1.2.) between group 1 and group 2 before surgery
- Difference in secondary outcomes (see 2.1.2.) before and after surgery under segmental blockade.
|
40 |
All |
18 Years and older (Adult, Older Adult) |
NCT01220362 |
093/10 |
|
October 2010 |
November 2011 |
November 2011 |
October 13, 2010 |
December 15, 2011 |
|
- Dep. of Anesthesiology and Pain Therapy, University Hospital Bern, 3010 Bern,Switzerland
Bern, BE, Switzerland
|
|
| 48 |
NCT01097499 |
Unknown † |
Low Level Laser (LED) Use to Increase Dental Implant Stability and Post Operative Analgesia |
|
- Device: OsseoPulse device (Light emitting diode technology)
|
Interventional
|
Not Applicable |
- Mount Sinai Hospital, Canada
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Implant stability
- Post-op analgesics
|
60 |
All |
Child, Adult, Older Adult |
NCT01097499 |
MSH-Biolux2010 |
|
April 2010 |
August 2010 |
October 2010 |
April 1, 2010 |
April 1, 2010 |
|
- Mount Sinai Hospital
Toronto, Ontario, Canada
|
|
| 49 |
NCT00860899 |
Completed |
Postoperative Pain and SIRS After Preoperative Analgesia With Clonidine or Levobupivacaine |
- Analgesia
- Pain
- Systemic Inflammatory Stress Response
|
- Drug: clonidine, levobupivacaine
|
Interventional
|
Phase 4 |
- University Hospital Dubrava
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Participant, Investigator)
- Primary Purpose: Treatment
|
- postoperative pain level
- systemic inflammatory stress response
|
42 |
All |
42 Years to 77 Years (Adult, Older Adult) |
NCT00860899 |
1860
1861 |
PPSAPACL |
December 2007 |
October 2008 |
May 2009 |
March 12, 2009 |
November 17, 2011 |
|
- University Hospital Dubrava
Zagreb, Croatia
|
|
| 50 |
NCT00789412 |
Completed |
Surgical Stress Index as a Tool for Monitoring Analgesia and/or Sedation in Critically Ill Patients |
- Analgesia
- Sedation
- Mechanical Ventilation
- (and 4 more...)
|
|
Observational
|
|
- University of Schleswig-Holstein
|
Other |
- Observational Model: Case Control
- Time Perspective: Cross-Sectional
|
|
60 |
All |
18 Years and older (Adult, Older Adult) |
NCT00789412 |
SSI-154-01 |
|
August 2008 |
August 2009 |
October 2009 |
November 11, 2008 |
October 28, 2009 |
|
- Institut für Anästhesiologie und Operative Intensivmedizin, Universitätsklinik Schleswig-Holstein, Campus Kiel
Kiel, Germany
|
|
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