97 studies found for:    Adenovirus cancer gene therapy
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Rank Status Study
1 Recruiting Phase 1 Trial of Interleukin 12 Gene Therapy for Locally Recurrent Prostate Cancer
Condition: Prostate Cancer
Intervention: Biological: Ad5-yCD/mutTKSR39rep-hIL12
2 Withdrawn Gene Therapy for Prostate Cancer That Returns After Radiation Therapy
Conditions: Prostatic Neoplasms;   Neoplasm Recurrence, Local
Intervention: Genetic: Ad.hIL-12
3 Completed A Study of an Infectivity Enhanced Suicide Gene Expressing Adenovirus for Ovarian Cancer in Patients With Recurrent Ovarian and Other Selected Gynecologic Cancers
Condition: Ovarian Cancer
Interventions: Genetic: Ad5.SSTR/TK.RGD;   Drug: Ganciclovir (GCV)
4 Completed
Has Results
Randomized Trial of Suicide Gene Therapy and Prostate Cancer
Condition: Prostate Cancer
Interventions: Biological: Ad5-yCD/mutTKSR39rep-ADP;   Radiation: IMRT
5 Completed Gene Therapy in Treating Patients With Advanced Bladder Cancer
Conditions: Recurrent Bladder Cancer;   Stage I Bladder Cancer;   Stage II Bladder Cancer;   Stage III Bladder Cancer;   Stage IV Bladder Cancer;   Transitional Cell Carcinoma of the Bladder
Intervention: Biological: Ad5CMV-p53 gene
6 Terminated Study Combining Suicide Gene Therapy With Chemoradiotherapy in the Treatment of Non-Metastatic Pancreatic Adenocarcinoma
Condition: Pancreatic Cancer
Intervention: Genetic: Ad5-yCD/mutTKSR39rep-ADP
7 Active, not recruiting Vaccination With Autologous Breast Cancer Cells Engineered to Secrete Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) in Metastatic Breast Cancer Patients
Condition: Breast Cancer
Intervention: Biological: Autologous, Lethally Irradiated Breast Cancer Cells
8 Active, not recruiting Autologous Vaccination With Lethally Irradiated, Autologous Breast Cancer Cells Engineered to Secrete GM-CSF in Women With Operable Breast Cancer
Condition: Breast Cancer
Intervention: Biological: Autologous, Lethally Irradiated Breast Cancer Cells
9 Completed Gene Therapy in Treating Patients With Recurrent Malignant Gliomas
Condition: Brain and Central Nervous System Tumors
Interventions: Biological: Ad5CMV-p53 gene;   Procedure: conventional surgery
10 Unknown  Gene Therapy in Treating Women With Metastatic Breast Cancer
Condition: Breast Cancer
Interventions: Biological: adenovirus-mediated human interleukin-12;   Other: enzyme-linked immunosorbent assay;   Other: fluorescence activated cell sorting;   Other: immunohistochemistry staining method;   Other: laboratory biomarker analysis
11 Completed Gene Therapy in Treating Patients With Primary Brain Tumors
Condition: Brain and Central Nervous System Tumors
Interventions: Biological: gene therapy;   Drug: chemotherapy;   Drug: ganciclovir;   Procedure: conventional surgery
12 Terminated Efficacy Study of Recombinant Adenovirus for Non Muscle Invasive Bladder Cancer
Conditions: Transitional Cell Carcinoma;   Bladder Cancer;   Carcinoma in Situ;   Carcinoma in Situ Concurrent With Papillary Tumors
Interventions: Biological: CG0070 adenovirus vector;   Other: Control Arm: Quadruple Choice
13 Not yet recruiting Trial of Stereotactic Body Radiation and Gene Therapy Before Nivolumab for Metastatic Non-Small Cell Lung Carcinoma
Conditions: Lung Squamous Cell Carcinoma Stage IV;   Nonsquamous Nonsmall Cell Neoplasm of Lung
Interventions: Biological: ADV/HSV-tk;   Drug: Valacyclovir;   Radiation: SBRT;   Drug: nivolumab
14 Terminated Gene Therapy in Treating Patients With Cancer of The Liver
Condition: Liver Cancer
Intervention: Biological: Ad5CMV-p53 gene
15 Completed Gene Therapy in Treating Patients With Recurrent or Progressive Brain Tumors
Condition: Brain and Central Nervous System Tumors
Interventions: Biological: recombinant adenovirus-p53 SCH-58500;   Procedure: conventional surgery
16 Terminated Wild Type p53 Adenovirus for Oral Premalignancies
Condition: Mouth Cancer
Intervention: Genetic: INGN 201
17 Active, not recruiting Vaccination With Autologous, Lethally Irradiated Melanoma Cells Engineered by Adenoviral Mediated Gene Transfer to Secrete Granulocyte-Macrophage Stimulating Factor (GMSF)
Condition: Melanoma
Intervention: Biological: Autologous, lethally irradiated melanoma cells
18 Active, not recruiting Gene Therapy for Pleural Malignancies
Conditions: Pleural Mesothelioma;   Metastatic Pleural Effusions
Interventions: Biological: Adenoviral-mediated Interferon-beta;   Biological: SCH 721015
19 Completed Gene Therapy Plus Radiation Therapy in Treating Patients With Non-Small Cell Lung Cancer
Condition: Lung Cancer
Interventions: Biological: Ad5CMV-p53 gene;   Radiation: radiation therapy
20 Unknown  Gene Therapy in Treating Patients With Advanced Recurrent or Persistent Ovarian Cancer or Primary Peritoneal Cancer
Conditions: Ovarian Cancer;   Peritoneal Cavity Cancer
Intervention: Biological: Ad5CMV-p53 gene

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Indicates status has not been verified in more than two years