823 studies found for:    ALA
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Rank Status Study
1 Not yet recruiting The Use of 5-aminolevulinic Acid (ALA) as an Intraoperative Tumor Marker for Resection of Pediatric Central Nervous System (CNS) Tumors
Condition: Central Nervous System Tumor, Pediatric
Intervention: Drug: 5ALA
2 Active, not recruiting A Study of Aminolevulinic Acid (ALA) to Enhance Visualization and Resection of Malignant Glial Tumors of the Brain
Condition: Glioma
Intervention: Drug: 5-Aminolevuline Acid
3 Completed Use Of The Dietary Supplement 5-ALA And Its Relationship With Sleep And Mood
Conditions: Insomnia;   Nocturnal Awakening;   Irritability;   Coping Behavior;   Stress
Interventions: Dietary Supplement: 5-Aminolevulinic Acid (5-ALA);   Dietary Supplement: Placebo
4 Recruiting Fluorescence and Glioma Heterogeneity
Condition: Malignant Gliomas
Intervention: Procedure: ALA Test group
5 Withdrawn A Study of the Specificity and Sensitivity of 5-ALA Fluorescence in Malignant Brain Tumors
Condition: Brain Neoplasms
Intervention: Drug: 5-aminolevulinic acid
6 Recruiting Safety Study of Aminolevulinic Acid (ALA) to Enhance Visualization and Resection of Tumors of the Brain
Condition: Glioma
Intervention: Drug: 5-Aminolevuline Acid
7 Active, not recruiting Gliadel Wafer and Fluorescence-Guided Surgery With 5-ALA Followed by Radiation Therapy And Temozolomide in Treating Patients With Primary Glioblastoma
Condition: Glioblastoma
Interventions: Drug: 5-ALA;   Drug: Gliadel wafers
8 Recruiting 5-ALA in Recurrent Glioma
Condition: Recurrent Glioma
Intervention: Drug: 5-ala
9 Recruiting Fluorescence-guided Surgery for Low- and High-grade Gliomas
Condition: Glioma
Interventions: Drug: 5-Aminolevulinic acid (ALA);   Drug: Placebo - ascorbic acid
10 Unknown  Safety Study of Aminolevulinic Acid (ALA) to Improve Visibility of Brain Tumors During Surgery
Conditions: Primary Glial Neoplasms of Brain;   Glioblastoma
Intervention: Drug: Aminolevulinic Acid
11 Not yet recruiting Intraoperative MRI and 5-ALA Guidance to Improve the Extent of Resection in Brain Tumor Surgery
Conditions: Primary Malignant Neoplasm of Nervous System;   Glioma;   Glioblastoma;   Metastasis
Interventions: Procedure: Interventional arm;   Procedure: Control arm
12 Withdrawn A Proof of Principle Study of Aminolevulinic Acid (ALA) - Induced Fluorescence Detection in Resectable Non-Small Cell Lung Cancer
Condition: Lung Cancer in Normal and Malignant Tumors
Intervention: Drug: ALA-induced Fluorescence
13 Completed
Has Results
Short-incubation Levulan Photodynamic Therapy Versus Vehicle for Face/Scalp Actinic Keratosis (AK)
Condition: Actinic Keratosis
Interventions: Drug: Broad Area ALA 1-hour incubation;   Drug: Broad Area ALA 2 hour incubation;   Drug: broad area ALA 3-hour incubation;   Drug: Spot ALA 2 hour incubation;   Drug: Vehicle PDT;   Device: Blue Light Treatment
14 Terminated Photodynamic Therapy Mediated by Topical Application of 5- ALA for the Treatment of Actinic Keratoses
Condition: Actinic Keratosis
Interventions: Drug: 5-ALA plus Blu-Light;   Drug: 5-FU, Imiquimod or treatment with cryotherapy
15 Terminated Aminolevulinic Acid During Surgery in Treating Patients With Malignant Brain Tumors
Conditions: Adult Anaplastic Astrocytoma;   Adult Anaplastic Oligodendroglioma;   Adult Giant Cell Glioblastoma;   Adult Glioblastoma;   Adult Gliosarcoma;   Adult Mixed Glioma;   Recurrent Adult Brain Tumor
Interventions: Drug: aminolevulinic acid;   Other: laboratory biomarker analysis;   Procedure: therapeutic conventional surgery
16 Not yet recruiting MUSE Study of Levulan Kerastick
Condition: Keratosis, Actinic
Interventions: Drug: Aminolevulinic Acid  (ALA);   Device: BLU-U
17 Completed Supplementation of Alpha-linolenic Acid (ALA)-Rich Oil in Humans
Conditions: Overweight;   Hypercholesterolemia
Interventions: Dietary Supplement: n-3 PUFA free olive oil;   Dietary Supplement: linseed oil
18 Recruiting More Complete Removal of Malignant Brain Tumors by Fluorescence-Guided Surgery
Conditions: Benign Neoplasms, Brain;   Brain Cancer;   Brain Neoplasms, Benign;   Brain Neoplasms, Malignant;   Brain Tumor, Primary;   Brain Tumor, Recurrent;   Brain Tumors;   Intracranial Neoplasms;   Neoplasms, Brain;   Neoplasms, Intracranial;   Primary Brain Neoplasms;   Primary Malignant Brain Neoplasms;   Primary Malignant Brain Tumors;   Gliomas;   Glioblastoma
Intervention: Drug: 5-ALA (Gliolan)
19 Withdrawn Topical 5-ALA-PDT With Blu-U Therapy Versus Topical 5-ALA With Pulse Dye Laser In Treating Recalcitrant Acne Vulgaris
Condition: Acne Vulgaris
Interventions: Drug: 5-ALA with Blu-U Light;   Drug: 5-ALA with Candela V-beam Pulse Dye Laser
20 Unknown  A Study of Aminolevulinic Acid Used to Enhance Visualization and Surgical Removal of Brain Tumors
Conditions: Malignant Glioma;   Glioma;   Glioblastoma;   Glioblastoma Multiforme;   Astrocytoma
Intervention: Drug: Aminolevulinic Acid

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Indicates status has not been verified in more than two years