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274 studies found for:    5-HT2A
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Rank Status Study
1 Completed Evaluation of [11C]Cimbi-36 as an Agonist PET Radioligand for Imaging of 5-HT2A Receptors
Condition: Healthy
Interventions: Drug: Citalopram and Pindolol;   Other: Placebo;   Dietary Supplement: Acute tryptophan depletion
2 Completed Neurobiological and Neurocognitive Disturbances in First-episode Schizophrenia
Condition: Schizophrenia
Intervention: Drug: quetiapine
3 Completed A Study To Examine The Distribution Of PF-05212377 In The Brain Of Healthy Volunteer Subjects Using Positron Emission Tomography And A Radioactive Tracer Following Oral Administration Of One Dose Of PF-05212377
Condition: Healthy
Intervention: Drug: PF-05212377
4 Completed SPECT Study With SB-773812 In Schizophrenic Patients
Condition: Schizophrenia
Intervention: Drug: SB773812 (risperidone)
5 Completed An Investigation of the Antidepressant Efficacy of the 5-HT2A Antagonist, M100907, in Combination With Citalopram in Treatment Resistant Depression
Condition: Depressive Disorder
Intervention: Drug: MDL100.907
6 Completed A Dose-Ranging Study of JNJ-40411813 in Healthy Male Volunteers
Condition: Healthy
Intervention: Drug: JNJ-40411813
7 Recruiting SYN120 a Dual 5-HT6/5-HT2A Antagonist Proof of Concept Study to Evaluate Its Safety, Tolerability and Efficacy in Parkinson's Disease Dementia (SYNAPSE)
Condition: Parkinson's Disease Dementia (PDD)
Interventions: Drug: SYN120;   Drug: Placebo
8 Completed The Role of 5-HT2A Receptor in the Perception of Self and Personal Meaning in Healthy Volunteers
Condition: Healthy
Interventions: Drug: Placebo;   Drug: LSD;   Drug: Ketanserin
9 Completed Trazodone for SSRI-sexual Dsyfunction
Condition: Sexual Dysfunction
Interventions: Drug: Trazodone;   Drug: Placebo
10 Completed Neuronal Correlates of Altered States of Consciousness
Condition: Healthy
Interventions: Drug: LSD;   Drug: Placebo
11 Completed ACP-103 to Treat Parkinson's Disease
Conditions: Parkinson's Disease;   Dyskinesias
Interventions: Drug: Intravenous Levodopa;   Drug: ACP-103
12 Completed Investigation of Serotonin Neurotransmission in MDMA Users Using Combinated Dexfenfluramine Challenge and PET Imaging
Conditions: Amphetamine-Related Disorders;   Amphetamine Abuse
Intervention: Drug: dexfenfluramine
13 Completed Effect of Atypical Antipsychotic Drugs Olanzapine and Amisulpride on Glucose Metabolism
Conditions: Schizophrenia;   Diabetes;   Insulin Resistance
Interventions: Procedure: Glucose clamp technique;   Drug: Amisulpride;   Drug: Olanzapine;   Drug: Placebo
14 Completed Predicting Medication Response in Obsessive Compulsive Disorder
Condition: Obsessive Compulsive Disorder
Interventions: Drug: clomipramine;   Drug: escitalopram;   Drug: duloxetine
15 Recruiting [11C]Cimbi-36 Dosimetry
Condition: Healthy
Interventions: Drug: [11C]Cimbi-36;   Drug: [11C]Cimbi-36-5
16 Completed
Has Results
PET Trial to Assess the Receptor Occupancy of Brexpiprazole in Adult Subjects With Schizophrenia
Condition: Schizophrenia
Intervention: Drug: Brexpiprazole 1mg to 4mg
17 Completed Safety and Efficacy of APD356 in the Treatment of Obesity
Condition: Obesity
Intervention: Drug: APD356
18 Completed Safety and Efficacy of APD356 in the Treatment of Obesity
Condition: Obesity
Intervention: Drug: APD356
19 Completed
Has Results
Dose-Finding Safety and Efficacy Trial of Org50081 (Esmirtazapine) in the Treatment of Vasomotor Symptoms (46101/P06459/MK-8265-012)
Conditions: Menopause;   Vasomotor Symptoms
Interventions: Drug: esmirtazapine;   Drug: Placebo
20 Completed Evaluate the Analgesic Efficacy and Safety of VVZ-149 Injection for Post-operative Pain Following Gastrectomy
Condition: Post-Operative Pain
Interventions: Drug: VVZ-149 injections;   Drug: Placebo

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Indicates status has not been verified in more than two years