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3749 studies found for:    5-HT
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Rank Status Study
1 Completed
Has Results
Fosaprepitant + 5HT3 Receptor Antagonists + Dexamethasone in Germ Cell Tumors
Condition: Chemotherapy-Induced Nausea and Vomiting
Interventions: Drug: Fosaprepitant;   Drug: Dexamethasone;   Drug: 5HT3
2 Recruiting Cerebral Pharmacodynamic Effects of 5-HT1B Receptor Stimulation
Condition: Healthy Volunteers
Intervention: Drug: Sumatriptan
3 Completed Evaluation of [11C]Cimbi-36 as an Agonist PET Radioligand for Imaging of 5-HT2A Receptors
Condition: Healthy
Interventions: Drug: Citalopram and Pindolol;   Other: Placebo;   Dietary Supplement: Acute tryptophan depletion
4 Completed Determine Central 5-HT1B Receptor Occupancy of ZOMIG® Rapimelt (Zolmitriptan) in Healthy Male Volunteers
Condition: Migraine
Interventions: Drug: Rapimelt;   Drug: [11C]AZ10419369
5 Unknown  Effects of Different Kinds, Different Doses of 5-HT3 Receptor Antagonists on Prevention of Hypotension
Conditions: Hypotension;   Shivering;   Nausea and Vomiting;   Vasopressor
Interventions: Drug: ramosetron;   Drug: ondansetron;   Drug: placebo
6 Recruiting Investigation of Serotonin Receptor Binding in the Migraine Brain Using Positron Emission Tomography
Condition: Migraine Without Aura
Intervention: Other: PET scan with two different 5-HT receptor ligands
7 Withdrawn Imaging Serotonin 5HT1A Receptors in Patients With Major Depressive Disorder
Conditions: Major Depression;   Unipolar Depression;   Depression;   Anxiety Disorder
Intervention: Other: Antidepressant (SSRI)
8 Completed Evaluation of [18F]MPPF as a Brain Tracer of Serotonin Receptor 5HT1a
Condition: Parkinson Disease
Intervention: Drug: [18F]MPPF
9 Active, not recruiting Investigating Serotonin Signalling in IBD Patients
Condition: Inflammatory Bowel Disease
10 Recruiting 5-HT3 Antagonists (Antiemetics) and Cardiac Safety
Condition: Adverse Reaction to Other Drugs and Medicines
Intervention: Drug: Ondansetron
11 Completed Positron Emission Tomography (PET) Study Investigating Dopamine and Serotonin Receptor Occupancy After Multiple Oral Dosing of Lu AF35700
Condition: Schizophrenia
Intervention: Drug: Lu AF35700
12 Not yet recruiting Treatment Outcome in Major Depressive Disorder
Condition: Major Depressive Disorder
Interventions: Drug: Escitalopram;   Drug: Duloxetine
13 Active, not recruiting 5HT3 Antagonists to Treat Opioid Withdrawal and to Prevent the Progression of Physical Dependence
Conditions: Opioid Withdrawal;   Physical Dependence
Intervention: Drug: Ondansetron
14 Completed Investigation of Serotonin Neurotransmission in MDMA Users Using Combinated Dexfenfluramine Challenge and PET Imaging
Conditions: Amphetamine-Related Disorders;   Amphetamine Abuse
Intervention: Drug: dexfenfluramine
15 Completed Neurobiological and Neurocognitive Disturbances in First-episode Schizophrenia
Condition: Schizophrenia
Intervention: Drug: quetiapine
16 Completed Tryptophan, Serotonin and Kynurenine in Septic Shock
Condition: Shock, Septic
17 Completed PET Imaging of Brain 5-HT(1A) Receptors Using [(11)C](-)-RWAY
Condition: Healthy Volunteers
Intervention: Drug: [11C] (-)-RWAY
18 Completed A Study To Examine The Distribution Of PF-05212377 In The Brain Of Healthy Volunteer Subjects Using Positron Emission Tomography And A Radioactive Tracer Following Oral Administration Of One Dose Of PF-05212377
Condition: Healthy
Intervention: Drug: PF-05212377
19 Completed An Investigation of the Antidepressant Efficacy of the 5-HT2A Antagonist, M100907, in Combination With Citalopram in Treatment Resistant Depression
Condition: Depressive Disorder
Intervention: Drug: MDL100.907
20 Completed SPECT Study With SB-773812 In Schizophrenic Patients
Condition: Schizophrenia
Intervention: Drug: SB773812 (risperidone)

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Indicates status has not been verified in more than two years