1 |
NCT00891358 |
Completed |
Empowerment Intervention for Young Women - Phase I |
- HIV
- Empowerment
- HIV Infections
|
- Behavioral: Prevention Empowerment Intervention for Young Women
|
Interventional |
Not Applicable |
- University of North Carolina, Chapel Hill
- National Institute on Drug Abuse (NIDA)
- National Institute of Mental Health (NIMH)
|
Other / NIH |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Prevention
|
- Use of focus groups for development/adaptation of a secondary prevention empowerment intervention to reduce sexual risk behavior among young women living with HIV.
|
17 |
Female |
16 Years to 24 Years (Child, Adult) |
NCT00891358 |
ATN 073 |
|
November 2008 |
July 2009 |
April 2013 |
May 1, 2009 |
March 6, 2017 |
|
- USF College of Medicine
Tampa, Florida, United States - Ruth M Rothstein CORE Center/ John H Stroger Jr Hospital
Chicago, Illinois, United States - University of Maryland Medical School
Baltimore, Maryland, United States
|
2 |
NCT02302950 |
Active, not recruiting |
A Retrospective Analysis of Raltegravir Use in Minority HIV Infected Women in Houston, Texas |
|
|
Observational |
|
- The University of Texas Health Science Center, Houston
|
Other |
- Observational Model: Other
- Time Perspective: Retrospective
|
- Assess the efficacy of raltegravir in study participants by measuring CD4 count and viral load
- Capture data on concomitant conditions that may have led to participants switching to raltegravir from medical records (eg. Diabetes mellitus)
- Assess tolerability of raltegravir by capturing symptoms
|
254 |
Female |
18 Years and older (Adult, Senior) |
NCT02302950 |
HSC-MS-14-0559 |
|
September 2014 |
December 2015 |
December 2017 |
November 27, 2014 |
May 22, 2017 |
|
- Thomas Street Clinic
Houston, Texas, United States
|
3 |
NCT03073421 |
Completed |
Positive Pregnancy Program |
- HIV Positive Pregnant Women
|
- Other: Qualitative interview
|
Interventional |
Not Applicable |
- St. Michael's Hospital, Toronto
|
Other |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Health Services Research
|
- Degree of satisfaction with P3 program during antenatal period
- Post-partum degree of satisfaction with P3 program
|
25 |
Female |
Child, Adult, Senior |
NCT03073421 |
12-124 |
P3 |
June 29, 2012 |
September 1, 2016 |
September 1, 2016 |
March 8, 2017 |
March 8, 2017 |
|
|
4 |
NCT00995176 |
Completed |
The Women's HIV SeroIncidence Study (ISIS) |
|
|
Observational |
|
- HIV Prevention Trials Network
- National Institute of Allergy and Infectious Diseases (NIAID)
|
Other / NIH |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Estimation of the overall HIV-1 incidence rate among 2,000 women in the US from defined geographic areas with high HIV prevalence and poverty
- Evaluation of laboratory assays for HIV-1 incidence determination
- Estimation of recruitment and retention rates
- (and 4 more...)
|
2099 |
All |
18 Years and older (Adult, Senior) |
NCT00995176 |
HPTN 064 1U01AI068619 |
|
April 2009 |
March 2011 |
March 2011 |
October 15, 2009 |
January 21, 2016 |
|
- George Washington University
Washington, District of Columbia, United States - The Ponce de Leon Center
Atlanta, Georgia, United States - Hope Clinic of the Emory Vaccine Center
Decatur, Georgia, United States - (and 6 more...)
|
5 |
NCT00067106 |
Completed |
Antiviral Therapy and HIV in the Female Genital Tract |
|
|
Observational |
|
- National Institute of Allergy and Infectious Diseases (NIAID)
|
NIH |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Antiviral Therapy and HIV in the Female Genital Tract
|
130 |
Female |
18 Years to 70 Years (Adult, Senior) |
NCT00067106 |
AI04350 |
|
July 2003 |
March 2007 |
March 2009 |
August 13, 2003 |
May 19, 2015 |
|
- The Miriam Hospital
Providence, Rhode Island, United States
|
6 |
NCT00062634 |
Unknown † |
Education Program to Promote Female Condom Use |
|
- Behavioral: Female condom skills training
|
Interventional |
Not Applicable |
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
|
NIH |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single
- Primary Purpose: Educational/Counseling/Training
|
- percent of sex acts protected by female condoms
- percent of sex acts protected by male or female condoms
|
400 |
Female |
18 Years to 39 Years (Adult) |
NCT00062634 |
HD39118 |
|
June 2003 |
|
August 2005 |
June 12, 2003 |
June 24, 2005 |
|
- Center for AIDS Prevention Studies, University of California, San Francisco
San Francisco, California, United States
|
7 |
NCT02136082 |
Active, not recruiting |
Asha Improving Health and Nutrition of Indian Women With AIDS and Their Children |
|
- Behavioral: Asha Support + Training
- Behavioral: Asha Support + Food
- Behavioral: Asha Support + Training + Food
- Behavioral: Asha Support Only
|
Interventional |
Not Applicable |
- University of California, Los Angeles
- All India Institute of Medical Sciences, New Delhi
|
Other |
- Allocation: Randomized
- Intervention Model: Factorial Assignment
- Masking: None (Open Label)
- Primary Purpose: Prevention
|
- Number of women living with HIV and their oldest child in India.
|
600 |
Female |
18 Years to 50 Years (Adult) |
NCT02136082 |
NIHMS098729 |
Asha II |
August 2013 |
August 2018 |
August 2018 |
May 12, 2014 |
November 7, 2017 |
|
- All India Institute of Medical Sciences (AIIMS)
New Delhi, India
|
8 |
NCT00961272 |
Completed |
Evaluating the Pharmacokinetics of 400 mg Oral Dose of Raltegravir in HIV-Infected Pre-Menopausal Women |
|
|
Observational |
|
- Kristine Patterson, MD
- Merck Sharp & Dohme Corp.
- University of North Carolina, Chapel Hill
|
Other / Industry |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- To describe the pharmacokinetics of raltegravir in cervicovaginal secretions as compared to blood plasma at steady-state in six HIV-positive women.
|
6 |
Female |
18 Years to 49 Years (Adult) |
NCT00961272 |
09-0889 |
|
July 2009 |
February 2010 |
February 2010 |
August 18, 2009 |
February 28, 2014 |
|
- The University of North Carolina at Chapel Hill
Chapel Hill, North Carolina, United States
|
9 |
NCT03033836 |
Recruiting |
Dolutegravir Plus Tenofovir/Lamivudine or Emtricitabine in HIV-1 Infected Transgender Women |
|
|
Interventional |
Phase 4 |
- The Huesped Foundation
- ViiV Healthcare
|
Other / Industry |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Proportion of transgender women retained in care at week 48
- Proportion of individuals with HIV RNA undetectable at week 48
- Percentage of Participants Experiencing Any Treatment-Emergent Laboratory Abnormality
- (and 6 more...)
|
60 |
Female |
18 Years and older (Adult, Senior) |
NCT03033836 |
FH-17 |
TRANSViiV |
December 2015 |
October 2017 |
December 2017 |
January 27, 2017 |
August 10, 2017 |
|
- Fundacion Huesped
Ciudad de Buenos Aires, Buenos Aires, Argentina
|
10 |
NCT00433979 |
Completed |
Study of Pharmacokinetics in HIV-infected Women |
|
- Drug: antiretroviral treatment
|
Observational |
|
- Women's College Hospital
- Canadian Institutes of Health Research (CIHR)
- Women's College Hospital
|
Other |
- Time Perspective: Prospective
|
|
88 |
Female |
18 Years to 65 Years (Adult) |
NCT00433979 |
HHP-79215 |
|
February 2007 |
February 2009 |
February 2009 |
February 12, 2007 |
July 30, 2012 |
|
- Children and Women's Hospital
Vancouver, British Columbia, Canada - St. Paul's Hospital
Vancouver, British Columbia, Canada - Downtown Infectious Diseases Clinic
Vancouver, British Columbia, Canada - (and 12 more...)
|
11 |
NCT01865786 |
Completed |
A Prospective, Observational Study of Pregnancy Outcomes Among Women Exposed to Truvada for PrEP Indication |
|
|
Observational |
|
|
Industry |
- Observational Model: Cohort
- Time Perspective: Retrospective
|
- Presence or absence of congenital malformations among infants born to HIV-1 uninfected women on FTC/TDF for PrEP
- Pregnancy outcomes in HIV-1 uninfected women who choose to continue or discontinue FTC/TDF for PrEP during their pregnancy as well as HIV-infected women treated with antiretrovirals
|
99 |
Female |
Child, Adult, Senior |
NCT01865786 |
GS-US-276-0101 |
|
January 1, 2013 |
March 13, 2018 |
March 13, 2018 |
May 31, 2013 |
March 30, 2018 |
|
- Antiretroviral Pregnancy Registry
Wilmington, North Carolina, United States
|
12 |
NCT01394133 |
Withdrawn |
Impact of Menstrual Cycle on Antiretroviral Pharmacokinetics in HIV-Infected Women |
|
- Drug: Tenofovir, Emtricitabine, Atazanavir, Ritonavir
|
Observational |
|
- University of Alabama at Birmingham
- National Institute of Allergy and Infectious Diseases (NIAID)
|
Other / NIH |
- Observational Model: Cohort
- Time Perspective: Prospective
|
|
0 |
Female |
21 Years to 40 Years (Adult) |
NCT01394133 |
F10102815 1K23AI074390-01A2 |
|
July 2011 |
April 2013 |
April 2013 |
July 14, 2011 |
April 30, 2013 |
|
- University of Alabama at Birmingham
Birmingham, Alabama, United States
|
13 |
NCT00722670 |
Completed |
Pregnant Women's CoOp |
|
- Behavioral: Woman-focused intervention
- Behavioral: Treatment as Usual
|
Interventional |
Phase 1 |
- RTI International
- National Institute on Drug Abuse (NIDA)
|
Other / NIH |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Prevention
|
- To compare the relative efficacy of the woman-focused intervention in reductions in substance abuse and sexual risk behaviors, maintain retention in drug treatment, reduce violence, and improve prenatal care and ARV treatment adherence (as needed).
- To explore the intervention's potential mechanisms of action and moderating factors that may influence response to the treatment.
|
100 |
Female |
18 Years and older (Adult, Senior) |
NCT00722670 |
R01DA020852 |
|
June 2007 |
February 2009 |
August 2010 |
July 25, 2008 |
May 9, 2013 |
|
- RTI International
RTP, North Carolina, United States
|
14 |
NCT02301507 |
Completed |
Study of Cell Phone SMS to Improve Adherence to ART in HIV Positive Young Women |
|
- Behavioral: cell phone SMS text messaging
|
Interventional |
Not Applicable |
- The University of Texas Health Science Center, Houston
|
Other |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Supportive Care
|
- Improve adherence to care and treatment in HIV infected young women. The outcome measure will be assessed by capturing kept medical appointments.
- assess improvements in stigma and depression in HIV infected women. The outcome measure will be assessed by questionaires.
|
7 |
Female |
18 Years to 40 Years (Adult) |
NCT02301507 |
HSC-MS-14-0692 |
|
November 2014 |
August 2015 |
July 2016 |
November 26, 2014 |
May 23, 2017 |
|
- Thomas Street Health Center
Houston, Texas, United States
|
15 |
NCT01625091 |
Completed Has Results |
Clinical Trial to Reduce Drinking in Women With HIV |
|
- Drug: Naltrexone
- Drug: Placebo
|
Interventional |
Phase 3 |
- University of Florida
- Florida International University
- University of Miami
- (and 2 more...)
|
Other / NIH |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Number of Participants Who Quit Hazardous Drinking
- Number of Binge Drinking Days
- Drinking Problems (SIP-2R Score)
- Craving for Alcohol
|
194 |
Female |
18 Years and older (Adult, Senior) |
NCT01625091 |
86-2012-N U01AA020797-01 |
WHATIF |
December 2012 |
July 2016 |
July 2016 |
June 21, 2012 |
April 6, 2018 |
August 2, 2017 |
- University of Miami
Coral Gables, Florida, United States - Florida International University
Miami, Florida, United States
|
16 |
NCT02920827 |
Completed |
Safety and Pharmacokinetic Trial in Healthy HIV-Negative Women to Assess the Delivery of Dapivirine From a Vaginal Ring |
|
- Combination Product: Dapivirine Vaginal Ring
- Combination Product: Placebo vaginal ring
|
Interventional |
Phase 1 |
- International Partnership for Microbicides, Inc.
|
Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Participant, Investigator)
- Primary Purpose: Prevention
|
- Safety: To assess the safety and tolerability of the dapivirine vaginal ring, the endpoint was the proportion of women on the dapivirine or placebo ring experiencing specific, protocol-defined safety events during the study (see description).
- Pharmacokinetics: assessed by measurement of the concentrations of dapivirine in plasma and in vaginal fluids (collected by Tear Test Strips) before, during and after the trial period.
|
16 |
Female |
18 Years to 40 Years (Adult) |
NCT02920827 |
IPM024 |
|
August 2009 |
April 2010 |
April 2010 |
September 30, 2016 |
September 8, 2017 |
|
- SGS Life Sciences Center
Antwerp, Flanders, Belgium
|
17 |
NCT01749566 |
Completed |
Exploring HIV Entry Blockade as a Pre-exposure Prophylaxis Strategy in Women |
|
|
Interventional |
Phase 1 |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Prevention
|
- Change in female genital tract maraviroc concentration
- Female genital tract HIV target cells
- Female genital tract T cell activation
- Vaginal microbiome
|
31 |
Female |
18 Years and older (Adult, Senior) |
NCT01749566 |
IRB00059752 KL2TR000455 ACTSIKL22012 |
MVC-PREP |
December 2012 |
May 2015 |
May 2015 |
December 13, 2012 |
July 9, 2015 |
|
- Grady Infectious Diseases Program
Atlanta, Georgia, United States
|
18 |
NCT00562874 |
Completed |
Nutrition Intervention in Drug Naive HIV-infected Kenyan Women and Their Children |
|
- Dietary Supplement: Meat Biscuit
- Dietary Supplement: Soy Biscuit
- Dietary Supplement: Wheat Biscuit
|
Interventional |
Not Applicable |
- Indiana University School of Health & Rehabilitation Sciences
- United States Agency for International Development (USAID)
- Moi Univeristy
- (and 4 more...)
|
Other / U.S. Fed |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Participant)
- Primary Purpose: Prevention
|
- The impact of meat intake on mid-upper-arm muscle area; comparisons between groups, of changes from baseline to 3, 6, 9, 12, 15, 18 mos (intervention); 24 mos (6 mos post intervention).
- The impact of meat intake on immune function (CD4 as well as percent of CD4 in the total lymphocyte); change from baseline to 6, 12, 18 mos (intervention), 24 months (6 mos post intervention)will be compared between groups
- The impact of meat intake on opportunistic infection (OI) incidence will be assessed monthly; change over time will be compared between groups from baseline through 18 mos (intervention and at 24 mos (6 mos post intervention).
|
808 |
All |
6 Months and older (Child, Adult, Senior) |
NCT00562874 |
0609-55 PCE-G-98-00036-00 |
HNP |
June 2006 |
June 2012 |
June 2012 |
November 22, 2007 |
April 5, 2013 |
|
- Moi University-Academic Model for the Prevention and Treatment of HIV
Eldoret, Rift Valley Province, Kenya
|
19 |
NCT01454921 |
Completed |
Development of an Empowerment Intervention for Young Women Living With HIV |
|
- Behavioral: Evolution: Young Women Taking Charge and Growing Stronger
|
Interventional |
Phase 2 |
- University of North Carolina, Chapel Hill
- National Institute on Drug Abuse (NIDA)
- National Institute of Mental Health (NIMH)
|
Other / NIH |
- Allocation: Non-Randomized
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Prevention
|
- Compare pre-intervention, immediate post-intervention, and 3-month post-intervention scores on sexual risk and psychological empowerment
- Compare pre-intervention, immediate post-intervention, and 3-month post-intervention scores on self-efficacy, sexual negotiation, relational violence, forgiveness, anger, substance use, life goals and outcomes, and affect regulation
|
43 |
Female |
16 Years to 24 Years (Child, Adult) |
NCT01454921 |
ATN 089 |
|
February 2010 |
October 2011 |
October 2011 |
October 19, 2011 |
February 28, 2017 |
|
- USF College of Medicine
Tampa, Florida, United States - Ruth M Rothstein CORE Center/ John H Stroger Jr Hospital
Chicago, Illinois, United States - University of Maryland Medical School
Baltimore, Maryland, United States
|
20 |
NCT01142817 |
Completed |
Metabolic and Psychological Changes Associated With Menopause Among Women With HIV |
|
|
Observational |
|
- Massachusetts General Hospital
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Bone Mineral Density
- Body Composition
- Lipid Levels
- (and 5 more...)
|
66 |
Female |
45 Years to 52 Years (Adult) |
NCT01142817 |
2009P-001315 |
|
June 2010 |
May 2013 |
May 2013 |
June 11, 2010 |
August 7, 2013 |
|
- Massachusetts General Hospital
Boston, Massachusetts, United States
|
21 |
NCT01111721 |
Completed |
Project POWER, Adapting Project SAFE: Reducing STD/HIV Risk in Women Prisoners |
|
- Behavioral: Project POWER HIV Risk-reduction Intervention
- Behavioral: NC DOC Standard of Care for STIs
|
Interventional |
Not Applicable |
- University of North Carolina, Chapel Hill
- Centers for Disease Control and Prevention
|
Other / U.S. Fed |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Prevention
|
- STI Infection Rate
- Number of unprotected sex acts as a measure of enacting sexual protective practices.
|
598 |
Female |
18 Years and older (Adult, Senior) |
NCT01111721 |
09-1433 5UR6PS000670 |
POWER |
March 2009 |
December 2012 |
December 2012 |
April 28, 2010 |
March 14, 2013 |
|
- North Carolina Correctional Institution for Women
Raleigh, North Carolina, United States - Fountain Correctional Center for Women
Rocky Mount, North Carolina, United States
|
22 |
NCT00840905 |
Completed |
A Study to Examine the Human Papillomavirus Types Exposure in Women From Southern Africa and Brasil |
|
|
Observational |
|
- Cynthia S Firnhaber
- Merck Sharp & Dohme Corp.
- University of Witwatersrand, South Africa
|
Other / Industry |
- Observational Model: Cohort
- Time Perspective: Retrospective
|
- To determine the seroprevalence of HPV types 6,11,16,18 in HIV serOpositive women for Botswana, South Africa and Brazil
|
487 |
Female |
18 Years and older (Adult, Senior) |
NCT00840905 |
Merck P0806 |
|
February 2009 |
March 2010 |
December 2010 |
February 11, 2009 |
November 7, 2012 |
|
- Shahin Lockman
Habarone, Botswana - Fundacao Oswaldo Cruz
Rio De Janeiro, Brazil - University of Witwatersrand/Helen Joseph Hospital
Johannesburg, South Africa
|
23 |
NCT00933140 |
Completed |
Anal HPV Infection and Abnormal Cytology in HIV-infected Women |
- Cervical Cancer Screening
- HIV Infections
|
|
Observational |
|
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Primary objective is to determine the rate of anal cytologic and histologic abnormalities in HIV infected women at Boston Medical Center.
- Identify risk factors for anal cytologic and histologic abnormalities in HIV infected women at BMC
|
100 |
Female |
18 Years to 64 Years (Adult) |
NCT00933140 |
H-25758 |
|
October 2006 |
September 2009 |
September 2009 |
July 7, 2009 |
November 17, 2015 |
|
- Boston Medical Center
Boston, Massachusetts, United States
|
24 |
NCT00246610 |
Completed |
Safety Of VIRACEPT® 625mg Administered To HIV-Infected Women During Pregnancy |
|
- Drug: Nelfinavir mesylate, 625 mg
|
Interventional |
Phase 4 |
|
Industry |
- Allocation: Non-Randomized
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Presence or absence of at least one adverse event related to or possibly related to nelfinavir of Grade 2 or greater severity as defined by the DAIDS Table for Grading of Severity of Adult Adverse Experiences in the gastrointestinal or hepatic category
- Development of primary or active site protease and nucleoside reverse transcriptase inhibitor-associated resistance mutations assessed using standard HIV genotype test on maternal plasma samples
- Presence or absence of at least one adverse event of Grade 3 or 4 severity in the hematologic, cardiovascular or metabolic categories defined by DAIDS Table or in the dermatologic category as defined by the Supplemental Toxicity Table
- (and 5 more...)
|
16 |
Female |
18 Years and older (Adult, Senior) |
NCT00246610 |
A4301017 |
|
March 2006 |
November 2007 |
November 2007 |
October 31, 2005 |
April 28, 2011 |
|
- Pfizer Investigational Site
Jacksonville, Florida, United States - Pfizer Investigational Site
Miami, Florida, United States - Pfizer Investigational Site
Metairie, Louisiana, United States - (and 3 more...)
|
25 |
NCT00621166 |
Completed |
Pharmacokinetics of Generic Lopinavir/Ritonavir in Pregnant Women |
|
- Drug: generic lopinavir/ritonavir
|
Interventional |
Phase 2 |
- The HIV Netherlands Australia Thailand Research Collaboration
|
Other |
- Allocation: Non-Randomized
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- To evaluate the pharmacokinetic profile of generic lopinavir/ritonavir tablets 200/50 mg in pregnant Thai HIV-infected women
- To determine the antiviral activity of generic lopinavir/ritonavir 400/100 mg BID in Thai pregnant women To determine the safety of generic lopinavir/ritonavir® 400/100 mg BID in Thai pregnant women Compare pharmacokinetics parameters before and after
|
20 |
Female |
18 Years to 40 Years (Adult) |
NCT00621166 |
HIV-NAT 093 approved |
|
June 2008 |
December 2009 |
December 2009 |
February 22, 2008 |
April 5, 2012 |
|
- Department of Obsterics and Gynecology, Faculty of Medicine, Chulalongkorn University
Bangkok, Thailand
|
26 |
NCT00705679 |
Completed Has Results |
Safety and Effectiveness of TFV 1% Gel, TDF Tablets, and FTC/TDF Tablets in Preventing HIV in Women |
|
- Drug: Emtricitabine/tenofovir disoproxil fumarate
- Drug: Emtricitabine/tenofovir disoproxil fumarate placebo
- Drug: Tenofovir disoproxil fumarate
- (and 3 more...)
|
Interventional |
Phase 2 |
- National Institute of Allergy and Infectious Diseases (NIAID)
- Microbicide Trials Network
|
NIH / Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Prevention
|
- Person-years of Follow-up of Tenofovir 1% Gel and Vaginal Placebo Gel Arms
- Number of HIV-1 Infections of Tenofovir 1% Gel and Vaginal Placebo Gel Arms
- Incidence Rate of HIV-1 Infections of Tenofovir 1% Gel and Vaginal Placebo Gel Arms
- (and 8 more...)
|
5029 |
Female |
18 Years to 45 Years (Adult) |
NCT00705679 |
MTN-003 (VOICE) 10622 MTN-003 5U01AI068633-05 VOICE |
|
August 2009 |
August 2012 |
August 2012 |
June 26, 2008 |
March 14, 2016 |
February 10, 2016 |
- Wits Reproductive Health and HIV Institute CRS (WRHI CRS)
Johannesburg, Gauteng, South Africa - Soweto MTN CRS
Johannesburg, Gauteng, South Africa - Overport CRS
Asherville, KwaZulu-Natal, South Africa - (and 12 more...)
|
27 |
NCT00326716 |
Completed Has Results |
Pharmacokinetics of Atazanavir/Ritonavir in HIV-1 Infected Pregnant Women |
|
- Drug: Atazanavir + Ritonavir + Combivir
|
Interventional |
Phase 1 |
|
Industry |
- Allocation: Non-Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Infant Gestational Age at Delivery
- Infant Gender
- Infant Race
- (and 24 more...)
|
69 |
Female |
18 Years and older (Adult, Senior) |
NCT00326716 |
AI424-182 |
|
June 2006 |
January 2009 |
August 2009 |
May 17, 2006 |
November 16, 2011 |
April 7, 2011 |
- Triple O Medical Services, P.A.
West Palm Beach, Florida, United States - Women's Hospital Of Texas
Houston, Texas, United States - Local Institution
San Juan, Puerto Rico - (and 3 more...)
|
28 |
NCT03293290 |
Recruiting |
Project EMPOWERING: Evidence-based PrEP for Justice-Involved Women and Their Risk Networks |
|
|
Interventional |
Phase 1 |
|
Other |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Prevention
|
- % PrEP uptake
- % eligible PrEP uptake
- Mean % PrEP adherence
- (and 2 more...)
|
100 |
Female |
18 Years and older (Adult, Senior) |
NCT03293290 |
1606017882 |
|
December 11, 2017 |
June 30, 2019 |
January 1, 2020 |
September 26, 2017 |
January 11, 2018 |
|
- Yale Clinical and Community Research, 270 Congress Ave
New Haven, Connecticut, United States
|
29 |
NCT00619320 |
Completed |
Reducing HIV: Safer Sex Skill Building in Pregnant Drug Abusing Women |
- HIV Infections
- Substance Use
|
- Behavioral: Safer Sex Skills Building (SSB)
|
Interventional |
Phase 2 Phase 3 |
- Virginia Commonwealth University
- National Institute on Minority Health and Health Disparities (NIMHD)
|
Other / NIH |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Prevention
|
- Number of penetrative unprotected sexual intercourse occasions
- The proportion of sex episodes involving alcohol or other drugs
- The proportion of penetrative unprotected sex occasions (of all sex occasions)
- Perceived self-efficacy to carry out safer sex and the carrying of condoms
|
380 |
Female |
18 Years and older (Adult, Senior) |
NCT00619320 |
P60MD002256 (Project 2 15378) P60MD002256 |
|
December 2008 |
August 2012 |
October 2012 |
February 20, 2008 |
February 12, 2013 |
|
- Richmond Behavioral Health Authority (RBHA)
Richmond, Virginia, United States - Virginia Commonwealth University, Nelson Womens Health (OB) Clinic
Richmond, Virginia, United States
|
30 |
NCT00095212 |
Completed Has Results |
Androgen Effects in HIV-infected Women |
|
- Drug: 1 Transdermal Testosterone (Patch)
- Drug: 2 Placebo Patch
|
Interventional |
Not Applicable |
- Massachusetts General Hospital
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
|
Other / NIH |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Lean Body Mass
- Bone Mineral Density of the Hip
- Quality of Life/Depression: Becks Depression Inventory
- (and 8 more...)
|
25 |
Female |
18 Years to 55 Years (Adult) |
NCT00095212 |
DK54167 (completed) R01DK054167 |
|
September 2004 |
April 2008 |
February 2009 |
November 2, 2004 |
April 14, 2010 |
March 15, 2010 |
- Mass General Hospital
Boston, Massachusetts, United States
|
31 |
NCT02527135 |
Completed |
Text Messaging to Improve HIV Testing Among Young Women in Kenya |
|
- Behavioral: Weekly HIV sensitization text messages
|
Interventional |
Not Applicable |
- University of Washington
- Grand Challenges Canada
- National Institutes of Health (NIH)
- John E. Fogarty International Center (FIC)
|
Other / NIH |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Prevention
|
- First HIV test
- Reported sexual behaviour patterns
- Self perception of risk
|
600 |
Female |
18 Years to 24 Years (Adult) |
NCT02527135 |
49533-EJ D43TW009580 S4 0254-01 |
T2T |
September 2013 |
August 2014 |
August 2014 |
August 18, 2015 |
August 18, 2015 |
|
- Partners in Health and Research Development (PHRD)
Nairobi, Kenya
|
32 |
NCT00076791 |
Completed |
Safety of Tenofovir Disoproxil Fumarate (TDF) and Emtricitabine/TDF in HIV Infected Pregnant Women and Their Infants |
|
- Drug: Emtricitabine/Tenofovir disoproxil fumarate
- Drug: Tenofovir disoproxil fumarate
|
Interventional |
Phase 1 |
- National Institute of Allergy and Infectious Diseases (NIAID)
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
- International Maternal Pediatric Adolescent AIDS Clinical Trials Group
|
NIH / Other |
- Allocation: Non-Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Prevention
|
- Adverse experiences with a severity of Grade 3 or 4 and adverse pregnancy outcomes that cannot be directly attributed to a cause besides study treatment
- Maternal viral load
- viral resistance to emtricitabine/tenofovir disoproxil fumarate using bulk sequencing
- infant HIV DNA PCR
|
66 |
Female |
18 Years and older (Adult, Senior) |
NCT00076791 |
P394 10034 PACTG 394 IMPAACT 394 |
|
March 2004 |
March 2010 |
March 2011 |
February 6, 2004 |
July 9, 2013 |
|
- Children's National Med. Ctr. Washington DC NICHD CRS
Washington, District of Columbia, United States - Washington Hosp. Ctr. NICHD CRS
Washington, District of Columbia, United States - Univ. of Miami Ped. Perinatal HIV/AIDS CRS
Miami, Florida, United States - (and 9 more...)
|
33 |
NCT01836003 |
Completed |
An Intervention to Improve Antenatal Access to CD4 Testing and HAART in Botswana |
|
- Other: Tokafatso programmatic intervention
|
Interventional |
Not Applicable |
- Harvard School of Public Health
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
|
Other / NIH |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Health Services Research
|
- Proportion of eligible pregnant women with CD4 enumeration prior to 26 weeks gestation
- Proportion of eligible women with HAART initiation prior to 30 weeks gestation
- Proportion of eligible women with CD4 testing prior to delivery
- (and 3 more...)
|
422 |
|
Child, Adult, Senior |
NCT01836003 |
BHP044 3R01HD044391-06S1 |
|
July 2011 |
October 2012 |
October 2012 |
April 19, 2013 |
April 19, 2013 |
|
- Botswana Harvard AIDS Institute
Gaborone, Botswana
|
34 |
NCT03490058 |
Recruiting New |
The Prevention Options for Women Evaluation Research (POWER) Cohort |
|
|
Observational |
|
- University of Washington
- Desmond Tutu HIV Centre
- Wits Reproductive Health and HIV Institute
- (and 5 more...)
|
Other / U.S. Fed |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Demonstrate PrEP delivery models for young women in different settings and geographies.
- PrEP initiation
- PrEP adherence
- HIV seroconversion
|
3000 |
Female |
16 Years to 25 Years (Child, Adult) |
NCT03490058 |
STUDY00000950 |
|
June 14, 2017 |
July 1, 2020 |
July 1, 2020 |
April 6, 2018 |
April 6, 2018 |
|
- Kenya Medical Research Institute
Kisumu, Kenya - Desmond Tutu HIV Foundation
Cape Town, South Africa - Wits Reproductive Health and HIV Institute
Johannesburg, South Africa
|
35 |
NCT03465852 |
Not yet recruiting |
HIV Prevention Among Latina Transgender Women Who Have Sex With Men: Evaluation of a Locally Developed Intervention |
|
|
Interventional |
Not Applicable |
- Centers for Disease Control and Prevention
|
U.S. Fed |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Prevention
|
- Uptake of PrEP
- Uptake of medically supervised hormone therapy
- Consistent condom use
|
140 |
Male |
18 Years and older (Adult, Senior) |
NCT03465852 |
IRB00040441 |
|
December 15, 2018 |
July 15, 2020 |
July 15, 2020 |
March 14, 2018 |
March 19, 2018 |
|
- Wake Forest University Health Sciences
Winston-Salem, North Carolina, United States
|
36 |
NCT02732730 |
Recruiting |
Uptake and Adherence to Daily Oral PrEP as a Primary Prevention Strategy for Young African Women: A Vanguard Study |
|
|
Interventional |
Phase 4 |
- HIV Prevention Trials Network
- National Institutes of Health (NIH)
- Gilead Sciences
- National Institute of Allergy and Infectious Diseases (NIAID)
|
Other / NIH / Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Prevention
|
- Proportion of women who accept vs decline Truvada at Enrollment
- Adherence to Truvada of women randomized to enhanced counseling vs standard
- Proportion of women who declined Truvada who elect to accept it during the study
- (and 4 more...)
|
600 |
Female |
16 Years to 25 Years (Child, Adult) |
NCT02732730 |
HPTN 082 UM1AI068619 12068 |
|
October 2016 |
July 2018 |
July 2018 |
April 11, 2016 |
October 21, 2016 |
|
- Wits Reproductive Health and HIV Institute
Johannesburg, Gauteng, South Africa - Emavundleni CRS
Cape Town, Western Cape, South Africa - Spilhaus CRS
Harare, Belgravia, Zimbabwe
|
37 |
NCT00653575 |
Completed |
Adult Sexual Risk Behavior Among Women With a History of Childhood Sexual Abuse |
- HIV Infections
- Child Abuse, Sexual
|
- Behavioral: Information-Motivation-Behavioral Skills model
- Behavioral: Traumagenic Dynamics model
|
Observational |
|
- Syracuse University
- National Institute of Mental Health (NIMH)
|
Other / NIH |
- Observational Model: Case Control
- Time Perspective: Retrospective
|
- Number of sexual partners
- Frequency of unprotected intercourse
- Proportion of episodes of unprotected intercourse
|
481 |
Female |
18 Years and older (Adult, Senior) |
NCT00653575 |
R21MH083502 DAHBR 9A-ASPQ |
|
August 2008 |
June 2010 |
June 2010 |
April 7, 2008 |
April 15, 2013 |
|
- Monroe County Health Department STD Clinic
Rochester, New York, United States
|
38 |
NCT01861431 |
Completed |
Evaluating a Microfinance Intervention for High Risk Women in Mongolia |
|
- Behavioral: HIV Sexual Risk reduction
- Behavioral: HIV Sexual Risk reduction plus Microfinance
|
Interventional |
Not Applicable |
- Columbia University
- National Institute of Mental Health (NIMH)
|
Other / NIH |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Participant, Outcomes Assessor)
- Primary Purpose: Prevention
|
- unprotected acts of vaginal and anal intercourse;
- proportion of protected vaginal and/or anal acts using barrier protection;
- number of sexual partners
- Proportion of income from sex work
|
107 |
Female |
18 Years and older (Adult, Senior) |
NCT01861431 |
AAAF4402 R34MH093227 |
|
April 2010 |
August 2013 |
December 2013 |
May 23, 2013 |
March 18, 2015 |
|
- Aira Toivgoo, co-PI
Ulaanbaatar,, Mongolia
|
39 |
NCT01853917 |
Completed |
Evaluation of Barriers to Postpartum Care in HIV Infected Women |
|
- Other: questionaires and structured interviews
|
Observational |
|
- The University of Texas Health Science Center, Houston
- M.D. Anderson Cancer Center
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- evaluate results from qualitative interviews
- evaluate results from questionaires
|
38 |
Female |
18 Years to 65 Years (Adult) |
NCT01853917 |
HSC-MS-11-0503 |
|
January 2012 |
February 2014 |
November 2014 |
May 15, 2013 |
December 4, 2014 |
|
- Harris County Hospital District Clinics-Thomas Street Clinic, Northwest Clinic
Houston, Texas, United States - Harris County Hospital District Clinics-LBJ hospital
Houston, Texas, United States
|
40 |
NCT01617096 |
Completed |
Phase 3 Safety and Effectiveness Trial of Dapivirine Vaginal Ring for Prevention of HIV-1 in Women |
|
- Combination Product: Dapivirine Vaginal Ring
- Combination Product: Placebo Ring
|
Interventional |
Phase 3 |
- International Partnership for Microbicides, Inc.
- National Institute of Allergy and Infectious Diseases (NIAID)
|
Industry / NIH |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Participant, Investigator)
- Primary Purpose: Prevention
|
- Efficacy as determined by the proportion of women in each arm with HIV-1 seroconversion after 120 endpoints are observed in the trial.
|
3540 |
Female |
18 Years to 45 Years (Adult) |
NCT01617096 |
MTN-020 UM1AI068633-06 |
ASPIRE |
June 2012 |
June 2015 |
June 2015 |
June 12, 2012 |
September 7, 2017 |
|
- College of Medicine - Johns Hopkins University Research Project
Blantyre, Malawi - UNC Project
Lilongwe, Malawi - CAPRISA, eThekwini Clinical Research Site
Durban, KwaZulu-Natal, South Africa - (and 4 more...)
|
41 |
NCT00825929 |
Recruiting |
Pharmacokinetics of Antiretroviral Agents in HIV-infected Pregnant Women. |
|
|
Observational |
|
- Radboud University
- PENTA Foundation
- Merck Sharp & Dohme Corp.
- (and 3 more...)
|
Other / Industry |
- Observational Model: Case-Crossover
- Time Perspective: Prospective
|
- Plasma concentrations of the compounds during pregnancy compared to the concentrations after delivery
- Pharmacokinetics in the neonate, in case of post-exposure prophylaxis with one of the agents under study.
- Safety of antiretrovirals during pregnancy
- viral load response and prevention of mother to child transmission of the virus
|
176 |
Female |
18 Years and older (Adult, Senior) |
NCT00825929 |
UMCN-AKF 08.02 |
PANNA |
February 2009 |
December 2020 |
December 2020 |
January 21, 2009 |
November 17, 2017 |
|
- Saint-Pierre University Hospital; Department of Infectious Diseases
Brussels, Belgium - CHARITÉ Berlin
Berlin, Germany - University of Bonn
Bonn, Germany - (and 21 more...)
|
42 |
NCT01952587 |
Completed |
X-linked Biological Response to HIV Sensing: the ANRS EP 53 Study |
|
- Biological: A peripheral blood sample
|
Interventional |
Not Applicable |
- French National Institute for Health and Medical Research-French National Agency for Research on AIDS and Viral Hepatitis (Inserm-ANRS)
|
Other |
- Allocation: Non-Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Basic Science
|
- Frequency (%) of subjects carrying the TRL7 c.32A>T SNP in HIV-infected and healthy women
- Frequency (%) of cells expressing the "A" and "T" alleles of TRL7 in interferon-alpha producing cells
|
90 |
Female |
18 Years and older (Adult, Senior) |
NCT01952587 |
ANRS EP 53 X LIBRIS 2013-A00954-41 |
X LIBRIS |
November 2013 |
June 2015 |
June 2015 |
September 30, 2013 |
July 1, 2015 |
|
- Purpan Hospital
Toulouse, France
|
43 |
NCT00666055 |
Completed |
Sex, Aging and Antiretroviral Pharmacokinetics |
|
- Drug: ARV regimen chosen by treating physician
|
Observational |
|
- Kristine Patterson, MD
- National Institute of Allergy and Infectious Diseases (NIAID)
- University of North Carolina, Chapel Hill
|
Other / NIH |
- Observational Model: Case Control
- Time Perspective: Prospective
|
- To measure and compare steady state blood plasma pharmacokinetics of antiretroviral therapies in post- and pre-menopausal HIV-infected women.
- To longitudinally quantify and compare genital tract antiretroviral drug exposure in post- and pre-menopausal HIV-infected women
- To determine and compare sexual HIV infectivity in post- and pre-menopausal HIV-infected women by measuring HIV RNA dynamics in blood plasma and genital tract secretions before and after the initiation of highly active antiretroviral therapy.
|
11 |
Female |
19 Years and older (Adult, Senior) |
NCT00666055 |
CID 0708 1K23AI077355-01 |
|
March 2008 |
May 2012 |
May 2012 |
April 24, 2008 |
September 20, 2012 |
|
- The University of North Carolina at Chapel Hill
Chapel Hill, North Carolina, United States
|
44 |
NCT00145561 |
Completed |
The Pharmacokinetic Study of Saquinavir New Tablet Formulation in HIV-Infected Pregnant Women. |
|
- Drug: Saquinavir and Ritonavir
|
Interventional |
Phase 1 Phase 2 |
- Radboud University
- Hoffmann-La Roche
|
Other / Industry |
- Allocation: Non-Randomized
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- pharmacokinetics at week 20 and 33 of gestation and 6 weeks post partum
- antiviral activity
- safety
|
40 |
Female |
18 Years to 40 Years (Adult) |
NCT00145561 |
UMCN-AKF 04.02 MV19059 |
|
August 2005 |
January 2008 |
February 2008 |
September 5, 2005 |
October 22, 2008 |
|
- University of Bonn
Bonn, Germany - University of Cologne
Köln, Germany - Rijnstate Hospital
Arnhem, Netherlands - (and 7 more...)
|
45 |
NCT00441909 |
Completed |
Phase I Study of Safety and Persistence of UC-781 Vaginal Microbicide |
|
- Drug: UC-781
- Drug: UC-781 placebo
|
Interventional |
Phase 1 |
- National Institute of Allergy and Infectious Diseases (NIAID)
- CONRAD
|
NIH / Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Participant, Care Provider)
- Primary Purpose: Prevention
|
- Local and systemic safety of a one-time dose of UC-781 0.1 % gel for vaginal use at different durations of exposure in HIV uninfected women
- Persistence of UC-781 0.1% gel following a single application
- Systemic absorption of UC-781 following a single application of 0.1% UC-781 gel
- (and 4 more...)
|
60 |
Female |
18 Years to 45 Years (Adult) |
NCT00441909 |
U19AI051661 |
|
April 2006 |
April 2008 |
April 2008 |
March 1, 2007 |
March 5, 2009 |
|
- Magee-Womens Hospital of University of Pittsburgh Medical Center
Pittsburgh, Pennsylvania, United States
|
46 |
NCT01843478 |
Completed |
The Self-Collection Study: a Study of Self-collected HPV Testing and Results Counseling |
|
- Other: Self-Collected HPV Test
- Other: Usual Care
|
Interventional |
Not Applicable |
- Johns Hopkins University
- National Institute of Nursing Research (NINR)
|
Other / NIH |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Prevention
|
|
97 |
Female |
18 Years and older (Adult, Senior) |
NCT01843478 |
NA_00071156 F31NR013633-01 |
|
October 2012 |
March 2014 |
March 2014 |
April 30, 2013 |
December 12, 2017 |
|
- Moore Clinic for HIV Care, Johns Hopkins Hospital
Baltimore, Maryland, United States
|
47 |
NCT00000910 |
Completed |
A Study to Collect Information About HIV-Positive Pregnant Women and Their Babies |
|
|
Observational |
|
- National Institute of Allergy and Infectious Diseases (NIAID)
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
|
NIH |
- Time Perspective: Prospective
|
|
2000 |
Female |
Child, Adult, Senior |
NCT00000910 |
ACTG 367 PACTG 367 11330 |
|
|
|
June 2004 |
August 31, 2001 |
October 7, 2013 |
|
- Brigham and Women's Hosp., Div. of Infectious Disease
Boston, Massachusetts, United States - Rutgers - New Jersey Medical School CRS
Newark, New Jersey, United States
|
48 |
NCT02371265 |
Completed |
Early ART Initiation Among HIV-positive Pregnant Women in Central Mozambique |
|
- Other: Adherence and retention package
|
Interventional |
Not Applicable |
- University of Washington
- Health Alliance International
- Beira Operations Research Center, Mozambique Ministry of Health
|
Other |
- Allocation: Randomized
- Intervention Model: Crossover Assignment
- Masking: None (Open Label)
- Primary Purpose: Health Services Research
|
- Retention at 30 days
- Adherence at 90 days
|
761 |
Female |
14 Years to 50 Years (Child, Adult) |
NCT02371265 |
1R01HD074557-01 |
|
April 2012 |
August 2015 |
August 2015 |
February 25, 2015 |
May 13, 2016 |
|
- Beira Operations Research Center
Beira, Sofala, Mozambique
|
49 |
NCT00109590 |
Completed Has Results |
Reducing the Incidence of Nevirapine Resistance Mutations in Pregnant HIV Infected Women Who Receive Anti-HIV Drugs Prior to and After Giving Birth |
|
- Drug: Didanosine, enteric-coated
- Drug: Lopinavir/ritonavir
- Drug: Nevirapine
- Drug: Zidovudine
|
Interventional |
Phase 2 |
- National Institute of Allergy and Infectious Diseases (NIAID)
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
|
NIH |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- The Proportion of Women Who Develop One or More New NVP Resistance Mutations as Identified by Consensus Sequencing or Oligonucleotide Ligation Assay in Plasma (Sampling Was Done at Days 10,21,30, and Weeks 5,6, and 8 Postpartum).
- The Proportion of Women in Each Randomized Arm Who Have One or More New NVP Resistance Mutations as Identified by Consensus Sequencing or Oligonucleotide Ligation Assay (OLA) in Plasma
- Area Under the Curve Pharmacokinetic Outcome for LPV/r. (AUC ug*hr/mL)
- (and 9 more...)
|
175 |
Female |
18 Years and older (Adult, Senior) |
NCT00109590 |
P1032 10137 PACTG P1032 |
|
June 2006 |
October 2008 |
November 2009 |
May 2, 2005 |
January 13, 2015 |
November 6, 2012 |
- Siriraj Hospital Mahidol University CRS
Bangkok, Bangkoknoi, Thailand - Bhumibol Adulyadej Hosp. CRS
Saimai, Bangkok, Thailand - Prapokklao Hosp. CRS
Chantaburi, Thailand - (and 4 more...)
|
50 |
NCT02333045 |
Terminated Has Results |
Characterization and Modulation of Mucosal Immunity for HIV Prevention in Women |
|
- Drug: Truvada qd
- Drug: Maraviroc 300 qd
|
Interventional |
Not Applicable |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Prevention
|
- Count of Total Cells Obtained From Cervicovaginal Lavage Samples
- Steady-state Area Under the Plasma Concentration-time Curve of Study Drug
- Steady-state Area Under the Female Genital Tract Concentration-time Curve of Study Drug
|
4 |
Female |
18 Years to 44 Years (Adult) |
NCT02333045 |
IRB00074767 |
MIP |
January 2015 |
October 28, 2016 |
October 28, 2016 |
January 7, 2015 |
January 19, 2018 |
December 13, 2017 |
- Grady Memorial Hospital
Atlanta, Georgia, United States - Grady Infectious Diseases Clinic (Ponce Clinic)
Atlanta, Georgia, United States
|