| 101 |
NCT02402803 |
Recruiting |
Dried Blood Spot- Statin Pilot Study |
- Hyperlipidemias
- Cardiovascular Diseases
|
- Other: Dried blood spot testing and phlebotomy
|
Observational |
|
- Cedars-Sinai Medical Center
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Clinical lipid and research protein measurements (composite)
- Biomarker change
- Research protein measurements in dried blood spot vs plasma
- Clinical Cardiovascular Risk Score
|
20 |
All |
18 Years and older (Adult, Senior) |
NCT02402803 |
Pro00037026 |
DBS |
October 2015 |
October 2018 |
October 2018 |
March 30, 2015 |
November 21, 2017 |
|
- Cedars Sinai Medical Center
Los Angeles, California, United States
|
| 102 |
NCT03404024 |
Recruiting |
Safety and Efficacy Study of Gene Therapy for Acute Myocardial Infarction in Korea |
- Ischemic Heart Disease
- Acute Myocardial Infarction
|
- Biological: Stage 1-Low dose VM202RY
- Biological: Stage 1-Middle dose VM202RY
- Biological: Stage 1-High dose VM202RY
- (and 4 more...)
|
Interventional |
Phase 2 |
|
Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Stage 1: MTD (maximum tolerated dose)
- Stage 2: LVEF (left ventricular ejection fraction) measured by cardiac MRI
- Change in left ventricular diameter (cardiac MRI)
- (and 15 more...)
|
108 |
All |
19 Years to 75 Years (Adult, Senior) |
NCT03404024 |
VMCAD-002 |
|
January 25, 2018 |
April 2020 |
April 2020 |
January 19, 2018 |
February 7, 2018 |
|
- GangNeung Asan Hospital
Gangneung, Korea, Republic of - Chonnam National University Hospital
Gwangju, Korea, Republic of - Ewha Womans University Medical Center
Seoul, Korea, Republic of - (and 2 more...)
|
| 103 |
NCT02322203 |
Recruiting |
Effects of Niacin Therapy on Lipoprotein Composition and Function |
|
- Dietary Supplement: Niacin Extended Release
|
Interventional |
Phase 2 |
- National Heart, Lung, and Blood Institute (NHLBI)
- National Institutes of Health Clinical Center (CC)
|
NIH |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Basic Science
|
- Changes in protein or lipid composition of any lipoprotein fraction and changes in vascular compliance as measured by CAVI
|
200 |
All |
18 Years to 99 Years (Adult, Senior) |
NCT02322203 |
150042
15-H-0042 |
|
December 20, 2014 |
April 7, 2019 |
July 3, 2019 |
December 23, 2014 |
March 2, 2018 |
|
- National Institutes of Health Clinical Center, 9000 Rockville Pike
Bethesda, Maryland, United States
|
| 104 |
NCT03297346 |
Recruiting |
Early Detection of Cardiovascular Changes After Radiotherapy for Breast Cancer |
|
- Other: Cardiac imaging and circulating biomarkers
|
Interventional |
Not Applicable |
- Institut de Radioprotection et de Surete Nucleaire
- Academisch Ziekenhuis Groningen
- Technische Universität München
- (and 3 more...)
|
Other |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Prevention
|
- Number of patients with decreased myocardial function assessed by echocardiography
- Changes in myocardial function measurements assessed by echocardiography
- Anatomical changes in coronary arteries assessed by cardiac CT
- (and 2 more...)
|
250 |
Female |
40 Years to 75 Years (Adult, Senior) |
NCT03297346 |
MEDIRAD EARLY-HEART_1.2 |
EARLY-HEART |
September 1, 2017 |
October 1, 2020 |
May 31, 2021 |
September 29, 2017 |
September 29, 2017 |
|
- IRSN - Clinique Pasteur
Toulouse, France - Klinikum rechts der Isar der Technischen Universität München
Munich, Germany - Academisch Ziekenhuis Groningen
Groningen, Netherlands - (and 2 more...)
|
| 105 |
NCT02783989 |
Recruiting |
Effects on Cardiovascular Risk Factors of the Endogenous Hydroxytyrosol Generation After the Combined Intake of Wine and Tyrosol in Humans |
|
- Other: white wine
- Dietary Supplement: tyrosol
|
Interventional |
Not Applicable |
|
Other |
- Allocation: Randomized
- Intervention Model: Crossover Assignment
- Masking: None (Open Label)
- Primary Purpose: Basic Science
|
- Metabolic: changes in hydroxytyrosol generation
- Vascular effects: changes in endothelial function
- Metabolic effects (n=12)
- (and 8 more...)
|
60 |
All |
50 Years to 80 Years (Adult, Senior) |
NCT02783989 |
IMIMFTCLFT/DOPET/3 |
DOPET3 |
January 20, 2016 |
December 31, 2017 |
June 2018 |
May 26, 2016 |
February 10, 2017 |
|
- IMIM (Hospital del Mar Medical Research Institute)
Barcelona, Spain
|
| 106 |
NCT03437642 |
Recruiting |
Psyhosomatic Medicine in Oncologic and Cardiac Disease Study |
- Acute Myocardial Infarction
- Tako Tsubo Cardiomyopathy
- Breast Cancer
|
- Behavioral: Short Term Psychotherapy
|
Observational |
|
- San Filippo Neri General Hospital
|
Other |
- Observational Model: Case-Control
- Time Perspective: Other
|
- Cumulative incidence of new relevant medical events
- Changes in body perception and dreams
- Incidence of rehospitalisations
- (and 6 more...)
|
220 |
All |
18 Years to 75 Years (Adult, Senior) |
NCT03437642 |
v24-9-2017 |
PSYCHONIC |
March 27, 2018 |
December 2022 |
December 2022 |
February 19, 2018 |
April 17, 2018 |
|
- San Filippo Neri General Hospital
Roma, Italy
|
| 107 |
NCT03387709 |
Recruiting |
UCSD Get Fit, Be Fit Study |
|
- Behavioral: Pistachio-enriched diet
- Behavioral: General dietary guidance diet
|
Interventional |
Not Applicable |
- University of California, San Diego
- American Pistachio Growers
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Prevention
|
- Weight Loss
- Metabolic and cardiovascular disease risk
|
100 |
All |
21 Years and older (Adult, Senior) |
NCT03387709 |
172109 |
|
April 4, 2018 |
June 2019 |
January 2020 |
January 2, 2018 |
April 10, 2018 |
|
- University of California, San Diego
La Jolla, California, United States
|
| 108 |
NCT03372733 |
Recruiting |
Dietary Omega-7 Palmitoleic Acid-Rich Oil on Lipoprotein Metabolism and Satiety in Adults |
|
- Drug: control olive oil (COO)
- Drug: palmitoleate-rich oil (PLO)
|
Interventional |
Phase 2 |
- National Heart, Lung, and Blood Institute (NHLBI)
- National Institutes of Health Clinical Center (CC)
|
NIH |
- Allocation: Randomized
- Intervention Model: Crossover Assignment
- Masking: Double (Participant, Investigator)
- Primary Purpose: Basic Science
|
- changes in the LDL-cholesterol levels
- changes in TC, TG, HDL-C, and other lipids, lipoprotein particle number, HDL functional test (i.e. efflux study) composition and size,changes in apetite and/or satiety
|
70 |
All |
18 Years to 100 Years (Adult, Senior) |
NCT03372733 |
180019
18-H-0019 |
|
March 19, 2018 |
July 31, 2020 |
July 31, 2020 |
December 14, 2017 |
March 14, 2018 |
|
- National Institutes of Health Clinical Center
Bethesda, Maryland, United States
|
| 109 |
NCT03466333 |
Not yet recruiting |
Postnatal Enalapril to Improve Cardiovascular fUnction Following Preterm Pre-eclampsia |
- Cardiovascular Diseases
- Pre-Eclampsia Onset Less Than 37 Weeks (Diagnosis)
|
- Drug: Enalapril Maleate
- Drug: Placebo oral capsule
|
Interventional |
Phase 2 |
- Manchester University NHS Foundation Trust
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Process outcome
- Clinical outcome
- Clinical outcome (echocardiography measures)
- Clinical outcome (biomarkers)
|
80 |
Female |
16 Years and older (Child, Adult, Senior) |
NCT03466333 |
R04725 |
PICk-UP |
May 2018 |
May 2020 |
November 2020 |
March 15, 2018 |
March 19, 2018 |
|
- Manchester University NHS Foundation Trust
Manchester, Greater Manchester, United Kingdom
|
| 110 |
NCT02590601 |
Recruiting |
Bromocriptine in the Treatment of Peripartum Cardiomyopathy |
- Peripartum Cardiomyopathy
|
- Drug: Bromocriptine
- Other: Guideline-driven medical therapy (GDMT)
|
Interventional |
Phase 3 |
- Montreal Heart Institute
- Canadian Cardiovascular Society
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- MACE
- Death from cardiovascular causes
- Left ventricular ejection fraction (LVEF) recovery
- (and 8 more...)
|
80 |
Female |
18 Years and older (Adult, Senior) |
NCT02590601 |
MP-33-2015-1874 (MP) |
BRO-HF |
January 1, 2017 |
January 1, 2023 |
January 1, 2023 |
October 29, 2015 |
September 6, 2017 |
|
- Montreal Heart Institute
Monteal, Quebec, Canada
|
| 111 |
NCT03235063 |
Recruiting |
Pregnancy and Dilated Cardiomyopathy |
|
- Other: routinely care- no intervention
|
Observational |
|
- Nantes University Hospital
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- evaluate clinical characteristics
- study maternal
- neonatal evolution
- (and 9 more...)
|
100 |
Female |
18 Years and older (Adult, Senior) |
NCT03235063 |
Prog 10/17 |
|
January 2, 2013 |
January 2, 2018 |
June 1, 2018 |
August 1, 2017 |
August 24, 2017 |
|
- Chu Angers
Angers, France - Chru de Brest
Brest, France - Hospital Henri Mondor
Créteil, France - (and 12 more...)
|
| 112 |
NCT03039140 |
Recruiting |
Cardiac Rehabilitation Program in Improving Cardiorespiratory Fitness in Stage 0-III Breast Cancer Survivors |
- Cancer Survivor
- Stage 0 Breast Cancer
- Stage IA Breast Cancer
- (and 6 more...)
|
- Other: Educational Intervention
- Behavioral: Exercise Intervention
- Other: Quality-of-Life Assessment
- Other: Questionnaire Administration
|
Interventional |
Not Applicable |
- Ohio State University Comprehensive Cancer Center
|
Other |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Supportive Care
|
- Feasibility of conducting a 14-week CR program
- Efficacy of CR in improving cardiorespiratory fitness
|
20 |
Female |
30 Years to 75 Years (Adult, Senior) |
NCT03039140 |
OSU-14060
NCI-2015-00810 |
|
May 14, 2015 |
September 30, 2018 |
September 30, 2018 |
February 1, 2017 |
January 8, 2018 |
|
- Ohio State University Comprehensive Cancer Center
Columbus, Ohio, United States
|
| 113 |
NCT03451747 |
Not yet recruiting |
The Potential Role of Testosterone on Target Organ Damage in Postmenopausal Hypertensive Women |
|
|
Observational |
|
|
Other |
- Observational Model: Case-Control
- Time Perspective: Retrospective
|
- Relative indexes of myocardial remodeling
- Ambulatory blood pressure monitoring
- The level of testosterone (T)
|
322 |
All |
45 Years to 65 Years (Adult) |
NCT03451747 |
LanZhou |
|
March 10, 2018 |
April 5, 2018 |
April 5, 2018 |
March 2, 2018 |
March 5, 2018 |
|
|
| 114 |
NCT03432468 |
Not yet recruiting |
Effect of Fully Blocking Type 1 Angiotensin Receptor on Target Organ Damage of Postmenopausal Hypertensive Women |
|
- Drug: Valsartan 1
- Drug: Valsartan 80 mg
|
Interventional |
Not Applicable |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Relative indexes of myocardial remodeling
- Ambulatory blood pressure monitoring
- Sexual hormones
|
102 |
All |
40 Years to 65 Years (Adult) |
NCT03432468 |
LanZhouU |
|
April 1, 2018 |
August 1, 2019 |
August 1, 2019 |
February 14, 2018 |
March 13, 2018 |
|
|
| 115 |
NCT03176615 |
Recruiting |
Meal-induced Thrombin Generation Before and After Gastric Bypass |
- Morbid Obesity
- Weight Loss
|
- Dietary Supplement: Experimental diet
|
Interventional |
Not Applicable |
- Hospital of South West Jutland
|
Other |
- Allocation: Randomized
- Intervention Model: Crossover Assignment
- Masking: None (Open Label)
- Primary Purpose: Prevention
|
- Postprandial peak mean of prothrombin fragment 1+2 concentrations
- Postprandial peak mean of cardiovascular risk markers concentrations
- Laboratory tests of fecal samples
|
30 |
All |
18 Years to 60 Years (Adult) |
NCT03176615 |
HospitalSWJ |
|
June 1, 2017 |
November 1, 2019 |
June 1, 2020 |
June 5, 2017 |
July 24, 2017 |
|
- Center of Bariatric Research, Dep. of Endocrinology, Hospital of South West Jutland
Esbjerg, Denmark
|
| 116 |
NCT02948439 |
Recruiting |
Prenatal Exercise and Cardiovascular Health (PEACH) |
|
|
Interventional |
Not Applicable |
- University of Alberta, Physical Education
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Basic Science
|
- Sympathetic Nerve Activity - cold pressor test response
- Respiratory measures - respiratory frequency
- Sympathetic Nerve Activity - breath hold response
- (and 30 more...)
|
100 |
Female |
18 Years and older (Adult, Senior) |
NCT02948439 |
Pro00061045 |
PEACH |
July 2016 |
April 2017 |
December 2017 |
October 28, 2016 |
October 28, 2016 |
|
- Program for Pregnancy and Postpartum Health, University of Alberta
Edmonton, Alberta, Canada
|
| 117 |
NCT02715661 |
Not yet recruiting |
Cerebrovascular Outcomes in Ischemic Heart Disease |
|
|
Interventional |
Not Applicable |
- Western University, Canada
- Lawson Health Research Institute
|
Other |
- Allocation: Randomized
- Intervention Model: Crossover Assignment
- Masking: None (Open Label)
- Primary Purpose: Basic Science
|
- cerebrovascular properties
- 1) vascular cognitive impairment
- 2) Brain grey matter and white matter mass, white matter hyperintensities
- (and 2 more...)
|
270 |
All |
18 Years to 80 Years (Adult, Senior) |
NCT02715661 |
107620 |
IHD |
March 2016 |
June 2019 |
June 2019 |
March 22, 2016 |
March 22, 2016 |
|
|
| 118 |
NCT01026571 |
Recruiting |
Identification of Genetic Mechanisms of Bicuspid Aortic Valve Disease |
|
|
Observational |
|
- Brigham and Women's Hospital
- Massachusetts General Hospital
- Brigham and Women's Hospital
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Identification of genetic variants associated with the occurrence of bicuspid aortic valve disease
|
4000 |
All |
18 Years to 80 Years (Adult, Senior) |
NCT01026571 |
2009P001639 |
BAV Genetics |
December 2009 |
December 2019 |
December 2019 |
December 4, 2009 |
January 18, 2018 |
|
- Massachusetts General Hospital
Boston, Massachusetts, United States
|
| 119 |
NCT02228408 |
Recruiting |
Safety and Cardiovascular Efficacy of Hydralazine and Isosorbide Dinitrate in Dialysis-Dependent ESRD |
- Chronic Hemodialysis (ESRD)
|
- Drug: Hydralazine/Isorsorbide Dinitrate
- Drug: Placebo
|
Interventional |
Phase 4 |
- Brigham and Women's Hospital
- Brigham and Women's Hospital
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Prevention
|
- Rate of hypotension, serious adverse events, gi events and cardiovascular death
- Efficacy-Change in coronary flow reserve (CFR) from 0-6 months
- Change in E' on TDI Echo from 0-6 months
- (and 4 more...)
|
16 |
All |
18 Years to 85 Years (Adult, Senior) |
NCT02228408 |
DK100772-01 |
HIDE |
August 28, 2017 |
April 15, 2019 |
December 15, 2020 |
August 29, 2014 |
October 5, 2017 |
|
- Brigham & Women's Hospital
Boston, Massachusetts, United States
|
| 120 |
NCT02653092 |
Recruiting |
Reprometabolic Syndrome Mediates Subfertility in Obesity |
- Obesity
- Infertility
- Hypogonadotropic Hypogonadotropism
- Hyperinsulinemia
|
- Drug: Insulin
- Drug: Intralipid
- Drug: Dextrose
- (and 3 more...)
|
Interventional |
Not Applicable |
- University of Colorado, Denver
|
Other |
- Allocation: Non-Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Basic Science
|
- Change in LH pulse amplitude
|
30 |
Female |
18 Years to 38 Years (Adult) |
NCT02653092 |
15-1052
UL1TR001082 |
|
June 2016 |
March 2018 |
March 2019 |
January 12, 2016 |
August 31, 2017 |
|
- University of Colorado Denver
Aurora, Colorado, United States
|
| 121 |
NCT02419898 |
Recruiting |
Oxfordshire Women and Their Children's Health |
- Pregnancy
- Pre-eclampsia
- Gestational Diabetes
- (and 4 more...)
|
|
Observational |
|
- Oxford University Hospitals NHS Trust
- University of Oxford
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Recruitment feasibility
- The retention of participants in Phase 2
- Incidence of pregnancy within 12 months of recruitment.
- (and 6 more...)
|
300 |
Female |
18 Years to 40 Years (Adult) |
NCT02419898 |
12/SC/0492 |
OxWATCH |
April 2013 |
September 2017 |
September 2017 |
April 17, 2015 |
October 3, 2016 |
|
- The Nuffield Department of Obstetrics and Gynaecology
Oxford, United Kingdom
|
| 122 |
NCT03379558 |
Recruiting |
Praluent® (Alirocumab) Pregnancy Exposure Registry: An OTIS Pregnancy Surveillance Study |
|
- Drug: ALIROCUMAB SAR236553 (REGN727)
|
Observational |
|
- Sanofi
- Regneron Pharmaceuticals
|
Industry / Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Rate of major structural birth defects
- Pregnancy outcome: Spontaneous abortion
- Pregnancy outcome: Elective abortion
- (and 10 more...)
|
375 |
Female |
Child, Adult, Senior |
NCT03379558 |
OBS14703
U1111-1195-6468 |
|
December 19, 2017 |
September 2028 |
September 2028 |
December 20, 2017 |
January 10, 2018 |
|
- New York, New York, United States
|
| 123 |
NCT02547584 |
Recruiting |
Impact of Anxiety on Cardiac Substrate Modification in Women With Atrial Fibrillation Undergoing Catheter Ablation |
|
- Procedure: Catheter ablation
|
Interventional |
Not Applicable |
- Texas Cardiac Arrhythmia Research Foundation
|
Other |
- Allocation: Non-Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Treatment
|
- Correlation between baseline anxiety score and prevalence of left atrial scar and non-pulmonary vein triggers
- Correlation of baseline anxiety score with scar severity
- Correlation of baseline TWBC and CRP level with the anxiety score
- (and 4 more...)
|
152 |
Female |
18 Years to 80 Years (Adult, Senior) |
NCT02547584 |
TCAI_AWARE |
AWARE |
September 2015 |
July 2018 |
July 2019 |
September 11, 2015 |
October 19, 2017 |
|
- Texas Cardiac Arrhythmia Institute, St. david's Medical Center
Austin, Texas, United States
|
| 124 |
NCT03503383 |
Recruiting
New |
Evaluation of Psychological Status in Pregnant Women Complaining of Hypertension With Pregnancy |
- Hypertension With Pregnancy
|
- Behavioral: Patient Health Questionnaire-9
- Behavioral: Generalized Anxiety Disorder Scale (GAD-7)
|
Observational |
|
|
Other |
- Observational Model: Case-Control
- Time Perspective: Cross-Sectional
|
- Depression Evaluation using Patient Health Questionnaire-9 (PHQ-9)
- Anxiety Evaluation using Generalized Anxiety Disorder Scale-7 (GAD-7)
|
100 |
Female |
20 Years to 40 Years (Adult) |
NCT03503383 |
MAbdalla1 |
|
March 1, 2018 |
October 1, 2018 |
December 1, 2018 |
April 19, 2018 |
April 19, 2018 |
|
- Minya Health Insurance Hospital
Minya, Egypt - Zagazig University Hospitals
Zagazig, Egypt
|
| 125 |
NCT03261245 |
Recruiting |
Relationship Between Multi-exposure to Noise and Air Pollution and the Onset of Hypertension Disorders During Pregnancy |
- Women Who Gave Birth at Dijon and Besançon CHUs Between 2005 and 2009
|
|
Observational |
|
- Centre Hospitalier Universitaire Dijon
|
Other |
- Observational Model: Case-Control
- Time Perspective: Retrospective
|
- Onset of a hypertension disorder during pregnancy
|
2650 |
Female |
Child, Adult, Senior |
NCT03261245 |
MARIET AOI 2016 |
HTA-BQuA |
March 2016 |
March 2018 |
March 2018 |
August 24, 2017 |
August 24, 2017 |
|
- CHU de BESANCON
Besancon, France - CHU Dijon Bourgogne
Dijon, France
|
| 126 |
NCT03076684 |
Recruiting |
Gender Differences in the Metabolic Effects of Uric Acid |
|
- Other: low-fructose diet
- Drug: Allopurinol
|
Interventional |
Early Phase 1 |
- University of Missouri-Columbia
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Basic Science
|
|
36 |
All |
40 Years to 70 Years (Adult, Senior) |
NCT03076684 |
2007093 |
|
March 3, 2017 |
May 2019 |
December 2019 |
March 10, 2017 |
April 4, 2018 |
|
- University of Missouri
Columbia, Missouri, United States
|
| 127 |
NCT03014791 |
Recruiting |
Influence of Age, Weight and Ethnic Background on Blood Pressure |
- Cardiovascular Diseases
- Vascular Diseases
- Hypertension
|
- Other: Brief lifestyle/medical history questionnaire
- Other: Anthropometric measures
- Other: Blood pressure and arterial stiffness
- (and 14 more...)
|
Observational |
|
- Cambridge University Hospitals NHS Foundation Trust
- University of Cambridge
|
Other |
- Observational Model: Case-Control
- Time Perspective: Cross-Sectional
|
- Cardiac Output (Measured by the inert gas re-breathing technique L/Min)
- Peripheral vascular resistance (Calculated using Cardiac Output and Blood pressure data dynes/sec/cm^5 )
- Pulse wave velocity (Measured by ECG-gated applanation tonometry meters/sec)
|
1000 |
All |
18 Years and older (Adult, Senior) |
NCT03014791 |
AWE |
AWE |
February 21, 2017 |
February 2022 |
February 2022 |
January 9, 2017 |
March 6, 2017 |
|
- Vascular Research Clinic, Addenbrooke's Hospital
Cambridge, Cambridgeshire, United Kingdom
|
| 128 |
NCT03426488 |
Recruiting |
Northern Sweden Health and Disease Study |
- Cardiovascular Diseases
- Cancer
- Neurodegenerative Diseases
- (and 2 more...)
|
- Behavioral: VIP - Västerbotten Intervention Programme
|
Observational |
|
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Number of deaths
- Numbers of incident cases of disease.
|
120000 |
All |
Child, Adult, Senior |
NCT03426488 |
Umu |
NSHDS |
January 1986 |
January 2026 |
January 2026 |
February 8, 2018 |
February 8, 2018 |
|
- Umeå University
Umeå, Västerbotten, Sweden
|
| 129 |
NCT02301663 |
Recruiting |
Development of a Novel Stress Testing Protocol to Define the Relationship Between Coronary Microvascular Dysfunction and Diastology in Women With Angina But No Evidence of Obstructive Coronary Artery Disease |
- Microvascular Coronary Dysfunction
|
- Other: Handgrip
- Other: Altitude simulation
- Other: Leg exercise
|
Interventional |
Not Applicable |
- Cedars-Sinai Medical Center
|
Other |
- Allocation: Non-Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Diagnostic
|
- Diastolic function by MRI
|
30 |
Female |
18 Years to 60 Years (Adult) |
NCT02301663 |
Diastolic stress testing |
|
November 2014 |
December 2017 |
December 2017 |
November 26, 2014 |
December 21, 2017 |
|
- Cedars-Sinai Medical Center
Los Angeles, California, United States
|
| 130 |
NCT01519297 |
Recruiting |
Preeclampsia: A Marker for Future Cardiovascular Risk in Women |
- Preeclampsia
- Pregnancy Induced Hypertension
|
|
Interventional |
Not Applicable |
- Brigham and Women's Hospital
- Brigham and Women's Hospital
|
Other |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Screening
|
- Vascular function
- Hormonal measurements
|
150 |
Female |
21 Years to 50 Years (Adult) |
NCT01519297 |
PP PE 2012 |
|
May 2012 |
June 2018 |
June 2018 |
January 26, 2012 |
January 23, 2018 |
|
- Brigham and Women's Hospital
Boston, Massachusetts, United States
|
| 131 |
NCT03482440 |
Recruiting
New |
Angiotensin II and Chronic Inflammation in Persistent Microvascular Dysfunction Following Preeclampsia |
|
- Drug: Salsalate Oral Tablet
- Drug: Placebo Oral Tablet
|
Interventional |
Early Phase 1 |
|
Other |
- Allocation: Randomized
- Intervention Model: Crossover Assignment
- Masking: Triple (Participant, Investigator, Outcomes Assessor)
- Primary Purpose: Basic Science
|
- change in endothelial function following salsalate treatment compared to placebo treatment
- change in inflammatory response to ang II compared to baseline
|
32 |
Female |
18 Years and older (Adult, Senior) |
NCT03482440 |
HL138133 |
|
August 23, 2017 |
August 2021 |
March 2023 |
March 29, 2018 |
March 29, 2018 |
|
- Pennsylvania State University
State College, Pennsylvania, United States
|
| 132 |
NCT00833313 |
Recruiting |
Gene Expression Profiling in Subjects With Postoperative Atrial Fibrillation After Cardiac Surgery |
|
|
Observational |
|
- Brigham and Women's Hospital
- Brigham and Women's Hospital
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
|
240 |
All |
20 Years to 80 Years (Adult, Senior) |
NCT00833313 |
2008-P000896 |
|
August 2008 |
August 2018 |
August 2018 |
February 2, 2009 |
March 12, 2018 |
|
- Brigham and Women's Hospital
Boston, Massachusetts, United States
|
| 133 |
NCT02641145 |
Recruiting |
Molecular Imaging of Primary Amyloid Cardiomyopathy |
- Amyloidosis, Primary
- Cardiomyopathy
|
- Radiation: F-18 florbetapir/C-11 acetate PET
- Device: MRI
- Radiation: N-13 ammonia PET
|
Interventional |
Not Applicable |
- Brigham and Women's Hospital
- National Institutes of Health (NIH)
- National Heart, Lung, and Blood Institute (NHLBI)
- (and 2 more...)
|
Other / NIH |
- Allocation: Non-Randomized
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Diagnostic
|
- Change in F-18 florbetapir myocardial retention index from baseline to 6 months and 12 months
- Change in Serum oxidative stress markers from baseline to 6 months and 12 months
- Change in Myocardial oxidative metabolism markers from baseline to 6 months
- (and 3 more...)
|
125 |
All |
18 Years to 99 Years (Adult, Senior) |
NCT02641145 |
2015P002477
1R01HL130563-01A1 |
MICA |
April 2016 |
April 2020 |
April 2020 |
December 29, 2015 |
December 4, 2017 |
|
- Brigham and Womens' Hospital
Boston, Massachusetts, United States
|
| 134 |
NCT01379573 |
Recruiting |
Preventive Approach to Congenital Heart Block With Hydroxychloroquine |
- Congenital Heart Block
- Neonatal Lupus
- Autoantibody-Associated Heart Block
|
|
Interventional |
Phase 2 |
- New York University School of Medicine
|
Other |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Prevention
|
- Recurrence of advanced heart block
- Prolonged PR interval (>150msec)
- Any sign of myocardial injury, without change in cardiac rate or rhythm
- (and 6 more...)
|
54 |
Female |
18 Years to 45 Years (Adult) |
NCT01379573 |
11-00369 |
PATCH |
January 2011 |
December 2018 |
December 2018 |
June 23, 2011 |
October 13, 2017 |
|
- New York University School of Medicine
New York, New York, United States
|
| 135 |
NCT03309293 |
Not yet recruiting |
Construction and External Validation of a Predictive Clinico-biological Score of the Risk of Venous Thrombosis in Women Under Combined Oral Contraceptives |
|
- Biological: blood samples
|
Interventional |
Not Applicable |
- Assistance Publique Hopitaux De Marseille
|
Other |
- Allocation: Non-Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Prevention
|
- Build a predictive score for VTE in women using COC
|
1501 |
Female |
18 Years and older (Adult, Senior) |
NCT03309293 |
2017-22
2017-A01591-52 |
PILGRIM |
October 2017 |
October 2021 |
February 2022 |
October 13, 2017 |
October 13, 2017 |
|
- Assistance Publique Hopitaux de Marseille
Marseille, France
|
| 136 |
NCT02856295 |
Not yet recruiting |
anti10a Levels in Women Treated With LMWH in the Postpartum Period |
|
|
Interventional |
Phase 4 |
- HaEmek Medical Center, Israel
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Prevention
|
- clexane dosing method in order to achieve anti 10a level >0.2
- incidence of anti 10a level of >0.6
- incidence of vein thromboembolism
- incidence of bleeding events
|
116 |
Female |
18 Years and older (Adult, Senior) |
NCT02856295 |
EMC59-12 |
|
August 2016 |
February 2019 |
February 2019 |
August 4, 2016 |
August 4, 2016 |
|
|
| 137 |
NCT02152696 |
Recruiting |
Optimal Treatment for Women With a Persisting Pregnancy of Unknown Location |
- Persistent Pregnancy of Unknown Location
- Ectopic Pregnancy
|
- Drug: Methotrexate
- Procedure: Uterine Evacuation
- Other: Expectant Management
|
Interventional |
Phase 3 |
- Yale University
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
- Augusta University
- (and 5 more...)
|
Other / NIH |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Uneventful clinical resolution of a Pregnancy of Unknown Location without change from the initial management strategy
|
276 |
Female |
18 Years and older (Adult, Senior) |
NCT02152696 |
ACTorNOT |
ACTorNOT |
May 2014 |
May 2019 |
May 2021 |
June 2, 2014 |
April 18, 2018 |
|
- University of California San Francisco
San Francisco, California, United States - University of South Florida
Tampa, Florida, United States - Augusta University
Augusta, Georgia, United States - (and 12 more...)
|
| 138 |
NCT02450318 |
Recruiting |
Acute Vascular Response to Exercise in Women With Nonobstructive Coronary Artery Disease |
- Nonobstructive Coronary Artery Disease
|
- Other: Slow-paced walking
|
Interventional |
Not Applicable |
|
Other |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Other
|
- Change in endothelium-dependent dilation
- Change in endothelium-independent dilation
- Change in arterial stiffness and wave reflection
|
150 |
Female |
18 Years to 89 Years (Adult, Senior) |
NCT02450318 |
IRB201500077 |
|
June 2015 |
June 2018 |
June 2018 |
May 21, 2015 |
June 21, 2017 |
|
- Integrative Cardiovasculal Physiology Laboratory
Gainesville, Florida, United States
|
| 139 |
NCT02145260 |
Recruiting |
Trial of Dialysate Sodium in Chronic Hospitalized Hemodialysis Patients |
- Intra-dialytic Hypotension
|
- Drug: Lower dialysate sodium (138 mmol/L; using Renasol hemodialysis concentrate)
- Drug: Higher dialysate sodium (142 mmol/L; using Renasol hemodialysis concentrate)
|
Interventional |
Not Applicable |
- Brigham and Women's Hospital
- Brigham and Women's Hospital
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Magnitude of intra-dialytic decline in systolic blood pressure
- Change in pre-dialysis high-sensitivity troponin I
|
200 |
All |
18 Years and older (Adult, Senior) |
NCT02145260 |
2014P000629 |
|
July 2014 |
June 2018 |
July 2018 |
May 22, 2014 |
February 1, 2017 |
|
- Brigham and Women's Hospital
Boston, Massachusetts, United States
|
| 140 |
NCT02240056 |
Recruiting |
Brain fMRT In Takotsubo Cardiomyopathy |
|
|
Observational |
|
- Wolfgang Dichtl, MD PhD
- Medical University Innsbruck
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Changes in brain functional MRT (resting state, paradigma) in postmenopausal females suffering from TTC as compared to NSTEMI / STEMI postmenopausal female patients
|
50 |
Female |
up to 90 Years (Child, Adult, Senior) |
NCT02240056 |
TAKINSULA |
TAKINSULA |
October 2014 |
December 2018 |
December 2019 |
September 15, 2014 |
March 21, 2018 |
|
- Medical University Innsbruck
Innsbruck, Tirol, Austria
|
| 141 |
NCT03372577 |
Recruiting |
Mindfulness-based Sex Therapy on Patients With Takotsubo Cardiomyopathy |
- Takotsubo Cardiomyopathy
- Sexual Dysfunction
|
- Behavioral: Mindfulness-Based Sex Therapy
- Other: Treatment as usual
|
Interventional |
Not Applicable |
- Qazvin University Of Medical Sciences
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Sexual functioning
- Sexual Distress
- Intimacy
- (and 8 more...)
|
450 |
Female |
18 Years and older (Adult, Senior) |
NCT03372577 |
IR.QUMS.REC.1396.188 |
|
December 1, 2017 |
December 1, 2018 |
July 1, 2019 |
December 13, 2017 |
December 13, 2017 |
|
- Booali Sina Hospital
Qazvin, Iran, Islamic Republic of
|
| 142 |
NCT02366871 |
Recruiting |
Oral Apixaban (Eliquis) Versus Enoxaparin (Lovenox) for Thromboprophylaxis in Women With Suspected Pelvic Malignancy |
- Gynecologic Cancer
- Venous Thromboembolism
|
- Drug: Oral apixaban
- Drug: Subcutaneous enoxaparin
|
Interventional |
Phase 2 |
- University of Colorado, Denver
- Bristol-Myers Squibb
|
Other / Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Prevention
|
- Incidence of major bleeding
- Incidence of DVT/PE events
|
400 |
Female |
18 Years to 89 Years (Adult, Senior) |
NCT02366871 |
15-0187.cc |
|
April 28, 2015 |
March 2018 |
March 2018 |
February 19, 2015 |
March 23, 2018 |
|
- University of Colorado Denver
Aurora, Colorado, United States
|
| 143 |
NCT02597790 |
Recruiting |
A Prospective, Longitudinal Study of Endothelial Function in HIV/HCV Coinfected Subjects |
|
|
Observational |
|
- University of California, Los Angeles
- Merck Sharp & Dohme Corp.
|
Other / Industry |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Reactive hyperemia index (RHI) by peripheral arterial tonometry (PAT)
- Soluble biomarkers (fasting lipid panel, hsCRP, IL-6, D-dimer, sICAM-1, sE-selectin, Lp-PLA2, sCD14, sCD163)
- Reactive hyperemia index (RHI)
- (and 6 more...)
|
120 |
All |
18 Years and older (Adult, Senior) |
NCT02597790 |
12-001792 (CTSI-PLACE)
N/A (Parent P30AI028697)
N/A (Parent UL1TR000124)
52767 |
CTSI-PLACE |
October 2013 |
January 2019 |
January 2019 |
November 5, 2015 |
October 26, 2017 |
|
- UCLA CARE Center
Los Angeles, California, United States
|
| 144 |
NCT02306538 |
Recruiting |
Evaluation of Myocardial Changes During BReast Adenocarcinoma Therapy to Detect Cardiotoxicity Earlier With MRI |
|
|
Observational |
|
- University Health Network, Toronto
- Canadian Institutes of Health Research (CIHR)
- University of Toronto
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- The presence of myocardial edema stratified by the presence or absence of conventionally defined cardiotoxicity (this is a binary outcome).
- The presence of edema stratified by the presence or absence of any drop in LVEF ≥5% by CMR by end of therapy (this is a binary outcome).
|
150 |
Female |
18 Years and older (Adult, Senior) |
NCT02306538 |
13-6543C |
EMBRACE-MRI |
October 2013 |
October 2019 |
January 2020 |
December 3, 2014 |
October 2, 2017 |
|
- Toronto General Hospital
Toronto, Ontario, Canada
|
| 145 |
NCT01993264 |
Recruiting |
Fetal Cardiac Strain Imaging Research |
|
- Other: Fetal Echocardiogram
|
Observational |
|
- Baylor College of Medicine
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Inter-observer variability of institutional imaging and analysis protocol
- Normative reference ranges for various measures of myocardial deformation
|
60 |
Female |
18 Years to 64 Years (Adult) |
NCT01993264 |
H-33343 |
|
October 2013 |
January 2015 |
December 2016 |
November 25, 2013 |
December 21, 2016 |
|
- Texas Children's Hospital
Houston, Texas, United States
|
| 146 |
NCT00776412 |
Recruiting |
Blood Markers of Inflammation, Blood Clotting and Blood Vessel Function in HIV-infected Adults |
|
|
Observational |
|
- National Institute of Allergy and Infectious Diseases (NIAID)
- National Institutes of Health Clinical Center (CC)
|
NIH |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Obtain blood samples for further investigation into the correlation between markers of coagulation, including D-dimer, and markers of platelet function, inflammation, endothelial cell function, and clinical parameters in HIV-infected adults.
|
375 |
All |
18 Years to 100 Years (Adult, Senior) |
NCT00776412 |
090013
09-I-0013 |
|
October 17, 2008 |
|
|
October 21, 2008 |
March 29, 2018 |
|
- National Institutes of Health Clinical Center, 9000 Rockville Pike
Bethesda, Maryland, United States
|
| 147 |
NCT02374892 |
Recruiting |
The CHAPTER III Study of Young Adolescents |
- Heart Defects, Congenital
|
- Behavioral: CHAPTER III Study Intervention
|
Interventional |
Not Applicable |
- University of Alberta
- Women and Children's Health Research Institute (WCHRI)
- Stollery Children's Hospital Foundation
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Participant)
- Primary Purpose: Other
|
- TRANSITION-Q Questionnaires
- MyHeart Scale
|
60 |
All |
13 Years to 14 Years (Child) |
NCT02374892 |
The CHAPTER III Study |
|
March 1, 2015 |
April 2018 |
October 2018 |
March 2, 2015 |
November 6, 2017 |
|
- Stollery Children's Hospital
Edmonton, Alberta, Canada
|
| 148 |
NCT03073447 |
Recruiting |
WAMIF : Young Women Presenting Acute Myocardial Infarction in France |
- Acute Myocardial Infarction
- Women Over 18 and Under 50 Years of Age
|
- Other: Specific blood sample of women under 50 years with acute MI
|
Interventional |
Not Applicable |
- French Cardiology Society
- French Federation of Cardiology
- I.V.S. Institut des Vaisseaux et du Sang
- (and 8 more...)
|
Other / Industry |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Other
|
- the combined endpoint of major cardiovascular events
- Anatomical characteristics of culprit lesions
- Frequency of the rare non atheromatous
- (and 7 more...)
|
200 |
Female |
18 Years to 50 Years (Adult) |
NCT03073447 |
2015-01 |
WAMIF |
May 4, 2017 |
November 2019 |
November 2020 |
March 8, 2017 |
February 26, 2018 |
|
- Chu Grenoble
Grenoble, France - Hôpital LARIBOISIERE
Paris, France
|
| 149 |
NCT03499925 |
Not yet recruiting
New |
Theory Construction and Effect of Intervention on Pregnant Women With Gestational Hypertension and Endocrine Disorders |
- Pregnancy-related Complications
|
- Behavioral: cognitive behaviors
- Behavioral: Telephone consultation
|
Interventional |
Not Applicable |
- National Taiwan University Hospital
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Participant)
- Primary Purpose: Supportive Care
|
|
300 |
Female |
20 Years and older (Adult, Senior) |
NCT03499925 |
201801053RINB |
|
April 23, 2018 |
July 31, 2021 |
July 31, 2021 |
April 17, 2018 |
April 20, 2018 |
|
- National Taiwan University Hospital
Taipei, Taiwan
|
| 150 |
NCT03417388 |
Recruiting |
Women's IschemiA TRial to Reduce Events In Non-ObstRuctive CAD |
|
- Drug: High dose potent statin
- Drug: Evolocumab
- Drug: ACE-I (lisinopril) or ARB (losartan)
- (and 3 more...)
|
Interventional |
Phase 4 |
- University of Florida
- United States Department of Defense
|
Other / U.S. Fed |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Treatment
|
- All Cause Death incidents reported between the two groups
- Non-fatal myocardial infarction (MI) incidents reported between the two groups
- Stroke/TIA incidents reported between the two groups
- (and 2 more...)
|
4422 |
Female |
18 Years to 100 Years (Adult, Senior) |
NCT03417388 |
IRB201701142 -A
PR161603 |
WARRIOR |
February 9, 2018 |
December 30, 2021 |
December 30, 2022 |
January 31, 2018 |
February 14, 2018 |
|
- Family Medicine at Eastside Community Practice
Gainesville, Florida, United States - Family Medicine at Hampton Oaks Medical Plaza (Adults and Peds)
Gainesville, Florida, United States - Internal Medicine at Tower Hill
Gainesville, Florida, United States - (and 8 more...)
|
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