27 studies found for:    Open Studies | copd | United States, North Carolina
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1 Recruiting Roflumilast in Chronic Obstructive Pulmonary Disease (COPD) Patients Treated With Fixed Dose Combinations of Long-acting β2-agonist (LABA) and Inhaled Corticosteroid (ICS)
Conditions: COPD;   COPD Exacerbation;   Lung Diseases;   Respiratory Disorders;   Pulmonary Disease;   Chronic Obstructive Lung Diseases;   Chronic Obstructive Airway Disease
Interventions: Drug: Roflumilast;   Drug: Placebo
2 Recruiting Evaluate the Effect of Aclidinium Bromide on Long-term Cardiovascular Safety and COPD Exacerbations in Patients With Moderate to Very Severe COPD
Conditions: COPD;   Chronic Obstructive Pulmonary Disease
Interventions: Drug: Aclidinium Bromide;   Drug: Placebo
3 Recruiting A Long-Term Safety Trial of Treatment With Nebulized SUN-101 in Patients With COPD
Condition: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: Drug: Glycopyrrolate (SUN-101 );   Drug: tiotropium (Spiriva®)
4 Recruiting Benralizumab Efficacy in Moderate to Very Severe Chronic Obstructive Pulmonary Disease (COPD) With Exacerbation History
Condition: Moderate to Very Severe Chronic Obstructive Pulmonary Disease
Interventions: Drug: Benralizumab Arm A;   Drug: Benralizumab Arm B;   Drug: Placebo
5 Recruiting Efficacy and Safety of Benralizumab in Moderate to Very Severe Chronic Obstructive Pulmonary Disease (COPD) With Exacerbation History
Condition: Moderate to Very Severe Chronic Obstructive Pulmonary Disease
Interventions: Drug: Benralizumab Arm A;   Drug: Benralizumab Arm B;   Drug: Benralizumab Arm C;   Drug: Placebo
6 Recruiting Comparing the Efficacy of Symbicort® pMDI and Formoterol Turbuhaler in Reducing Exacerbations in Patients With Cronic Obstructive Pulmonary Disease
Condition: COPD Patients
Interventions: Drug: Symbicort;   Drug: Formoterol turbohaler;   Other: Placebo for Symbicort pMDI;   Other: Placebo for Formoterol Turbohaler
7 Recruiting A Study of Arformoterol Tartrate Inhalation Solution and Tiotropium Bromide on Re-hospitalization in Chronic Obstructive Pulmonary Disease (COPD) Subjects
Condition: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: Drug: Arformoterol tartrate inhalation solution;   Drug: Tiotropium
8 Recruiting A Phase IIa Study to Investigate the Efficacy and Safety of AZD7624 in Chronic Obstructive Pulmonary Disease (COPD) Patients While on Maintenance Therapy
Condition: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: Drug: AZD7624 1.0 mg;   Drug: Placebo
9 Recruiting A Study Comparing the Efficacy, Safety and Tolerability of Fixed Dose Combination (FDC) of FF/UMEC/VI With the FDC of FF/VI and UMEC/VI; Administered Once-daily Via a Dry Powder Inhaler (DPI) in Subjects With Chronic Obstructive Pulmonary Disease (COPD)
Condition: Pulmonary Disease, Chronic Obstructive
Interventions: Drug: fluticasone furoate (FF);   Drug: vilanterol (VI);   Drug: umeclidinium bromide (UMEC)
10 Recruiting Efficacy and Safety Trial of 12 Weeks of Treatment With Nebulized SUN-101 in Patients With COPD (GOLDEN-4)
Conditions: COPD;   Chronic Obstructive Pulmonary Disease
Interventions: Drug: SUN-101;   Drug: Placebo
11 Recruiting Ex-vivo Perfusion and Ventilation of Lungs Recovered From Non-Heart-Beating Donors to Assess Transplant Suitability
Conditions: Emphysema;   Chronic Obstructive Pulmonary Disease (COPD);   Cystic Fibrosis;   Pulmonary Fibrosis;   Bronchiectasis;   Sarcoidosis;   Pulmonary Hypertension;   Alpha-1 Antitrypsin Deficiency
Interventions: Procedure: Transplantation of lungs obtained from Non-Heart-Beating Donors (NHBDs) after ex-vivo perfusion w/ STEEN Solution™;   Device: STEEN Solution™
12 Recruiting Study of COPD Subgroups and Biomarkers
Conditions: COPD;   Chronic Obstructive Pulmonary Disease;   Chronic Bronchitis;   Emphysema
Intervention:
13 Recruiting Study Evaluating the Efficacy and Safety of Fluticasone Furoate/Vilanterol Inhalation Powder (FF/VI) Compared With Vilanterol Inhalation Powder (VI) in Subjects With Chronic Obstructive Pulmonary Disease (COPD)
Condition: Pulmonary Disease, Chronic Obstructive
Interventions: Drug: Fluticasone Furoate/Vilanterol;   Drug: Vilanterol
14 Recruiting Efficacy and Safety Trial of 12 Weeks of Treatment With Nebulized SUN-101 in Patients With COPD
Condition: COPD
Interventions: Drug: SUN101;   Drug: Placebo
15 Recruiting Study to Evaluate Efficacy and Safety of Mepolizumab for Frequently Exacerbating Chronic Obstructive Pulmonary Disease (COPD) Patients
Condition: Pulmonary Disease, Chronic Obstructive
Interventions: Drug: Mepolizumab;   Drug: Placebo
16 Recruiting Efficacy and Safety of Mepolizumab as an Add-on Treatment in Chronic Obstructive Pulmonary Disease (COPD)
Condition: Pulmonary Disease, Chronic Obstructive
Interventions: Drug: Mepolizumab;   Drug: Placebo
17 Recruiting Comparing the Efficacy of Tiotropium + Olodaterol (5/5 µg) Fixed Dose Combination (FDC) Over Tiotropium 5µg in Reducing Moderate to Severe Exacerbations in Patients With Severe to Very Severe Chronic Obstructive Pulmonary Disease.
Condition: Pulmonary Disease, Chronic Obstructive
Interventions: Drug: olodaterol;   Drug: tiotropium
18 Unknown  Evaluation of FeNO During and Following Acute COPD Exacerbation
Condition: Chronic Obstructive Pulmonary Disease
Intervention: Device: NIOX MINO®
19 Recruiting Sustained Effects of Hypertonic Saline on Mucociliary Clearance in Subjects With Chronic Bronchitis
Conditions: Chronic Obstructive Pulmonary Disease;   COPD;   Chronic Bronchitis
Intervention: Other: Inhaled 7% HS (NaCl) home treatment
20 Not yet recruiting Novel Therapies for Muco-Obstructive Lung Diseases: Testing the Transnasal Pulmonary Delivery Device in COPD/CB Subjects
Conditions: COPD;   Chronic Bronchitis
Interventions: Device: tPAD;   Device: 7% hypertonic saline (510K approved as a device)

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Indicates status has not been verified in more than two years