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37 studies found for:    Open Studies | Type 1 Diabetes | NIH
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Rank Status Study
1 Recruiting Type 1 Diabetes Extension Study
Conditions: Type 1 Diabetes;   Diabetes Mellitus
Intervention:
2 Recruiting CTLA4-Ig (Abatacept)for Prevention of Abnormal Glucose Tolerance and Diabetes in Relatives At -Risk for Type 1
Conditions: Abnormal Glucose Tolerance;   Type 1 Diabetes
Interventions: Drug: CTLA4-Ig (Abatacept);   Drug: Placebo
3 Recruiting Immune Effects of Oral Insulin in Relatives at Risk for Type 1 Diabetes Mellitus (TN20)
Condition: Type 1 Diabetes
Interventions: Drug: 67.5 mg oral insulin crystals daily;   Drug: 500mg oral insulin crystals every other week
4 Recruiting Reducing Distress And Improving Glycemic Control In Adults With Type 1 Diabetes
Condition: Type 1 Diabetes Mellitus
Interventions: Behavioral: 'KnowIt';   Behavioral: 'OnTrack'
5 Recruiting New Onset Type 1 Diabetes: Role of Exenatide
Condition: Type 1 Diabetes
Interventions: Drug: Exenatide;   Drug: Rapid and long acting insulin;   Drug: long acting insulin + rapid acting + 1.25 mcg Exenatide
6 Recruiting Incentives, Cognitive Training and Internet Therapy for Teens With Poorly Controlled Type 1 Diabetes
Condition: Type 1 Diabetes
Interventions: Behavioral: MAxIM;   Behavioral: Usual Care
7 Recruiting Pathway to Prevention Study
Condition: Diabetes Mellitus, Type 1
Intervention:
8 Recruiting Teplizumab for Prevention of Type 1 Diabetes In Relatives "At-Risk"
Conditions: Autoantibody Positive;   Non-diabetic Relatives at Risk for Type 1 Diabetes;   High Risk;   Impaired Glucose Tolerance
Intervention: Drug: Teplizumab
9 Recruiting Tocilizumab (TCZ) in New-onset Type 1 Diabetes
Conditions: Type 1 Diabetes Mellitus;   New-onset Type 1 Diabetes Mellitus;   T1DM;   T1D
Interventions: Drug: Tocilizumab (TCZ);   Drug: Placebo
10 Recruiting Insulin-Glucose-Glucagon Network: Defining a Type 1 Diabetes Progression Index
Condition: Diabetes Mellitus, Type 1
Interventions: Procedure: Metabolic Challenge Admission;   Other: CGM home test
11 Recruiting iOmit: Reducing Intentional Insulin Misuse in Type 1 Diabetes
Conditions: Type 1 Diabetes Mellitus;   Eating Disorders
Interventions: Behavioral: Therapy with Mobile App Enhancement;   Device: Recovery Record (RR) Mobile app
12 Recruiting Effect of Canagliflozin in T1DM (Type 1 Diabetes Melitus) After Interruption of Continuous Subcutaneous Insulin Infusion
Condition: Type 1 Diabetes
Interventions: Drug: canagliflozin;   Other: basal interruption without canagliflozin
13 Recruiting Glucose Counterregulation in Long Standing Type 1 Diabetes
Conditions: Hypoglycemia Unawareness;   Type 1 Diabetes;   Healthy
Intervention: Device: RT-CGM
14 Recruiting Hypoglycemia Associated Autonomic Failure in Type 1 Diabetes Mellitus
Condition: Type 1 Diabetes
Interventions: Drug: Dehydroepiandrosterone;   Drug: Placebo
15 Recruiting Tissue-Specific Metabolic Reprogramming in Diabetic Complications
Condition: Type 1 Diabetes Mellitus
Interventions: Procedure: Euglycemic clamp (normal blood sugar clamp) for 4 hours;   Procedure: hyperglycemic clamp (elevated blood sugar to 300) for 4 hours
16 Recruiting Hypoglycemia Associated Autonomic Failure in Type 1 Diabetes Mellitus (DM)
Conditions: Type 1 Diabetes;   Hypoglycemia Associated Autonomic Failure
Interventions: Drug: Fluoxetine;   Drug: Placebo control
17 Recruiting Feasibility of a Decision Support System to Reduce Glucose Variability in Subject With T1DM
Condition: Type 1 Diabetes Mellitus
Intervention: Device: Decision Support System
18 Recruiting Investigation Into the Effects Upon Brain Response to Change in Cirucating Glose Levels in Diabetes Mellitus
Conditions: Type 1 Diabetes;   Hypoglycemia
Intervention:
19 Recruiting MMPPC: A Probabilistic Closed-loop Artificial Pancreas to Handle Unannounced Meals and Exercise
Condition: Type 1 Diabetes
Interventions: Device: Inpatient use of the MMPPC/DiAs system;   Device: Outpatient use of the MMPPC/DiAs system
20 Recruiting A Reinforcement Approach to Improve Diabetes Management
Condition: Type 1 Diabetes
Interventions: Behavioral: Reinforcement for BG testing;   Other: Standard of care

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Study has passed its completion date and status has not been verified in more than two years.