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58 studies found for:    GVHD AND steroid refractory
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Rank Status Study
1 Unknown  Study of Rituximab in Patients With Steroid-Refractory Chronic Graft-Versus-Host Disease
Condition: Steroid-Refractory Chronic GVHD
Intervention: Drug: Rituximab
2 Recruiting UVADEX® and ECP for the Treatment of Pediatric Patients With Steroid Refractory Acute Graft Versus Host Disease
Condition: Steroid Refractory Acute Graft Versus Host Disease
Intervention: Drug: UVADEX® (methoxsalen) Sterile Solution in Conjunction with the THERAKOS® CELLEX® Photopheresis System
3 Active, not recruiting Infliximab and Basiliximab for Treatment of Steroid Refractory Acute Graft Versus Host Disease
Conditions: Graft Versus Host Disease;   Steroid Refractory GVHD;   Acute GVH Disease
Intervention: Drug: Infliximab and Basiliximab
4 Recruiting Continuous Alloreactive T Cell Depletion and Regulatory T Cell Expansion for the Treatment of Steroid-refractory or Dependent Chronic GVHD
Condition: Chronic GVHD After HCT for Cancer or Immune Disease
Intervention: Other: Autologous peripheral blood mononuclear cells ex vivo depleted for reactive T cells, using TH9402 based photodynamic therapy, in a final formulation of 10% DMSO, 30% autologous plasma in PlasmaLyte.
5 Completed Brentuximab Vedotin for Steroid Refractory GvHD
Condition: Graft vs. Host Disease
Intervention: Drug: Brentuximab Vedotin
6 Completed Allogenic Bone Marrow Mesenchymal Stem Cells Infusion in Patients With Steroid-refractory GVHD
Condition: Graft Versus Host Disease
Intervention: Biological: Mesenchymal Stem Cells
7 Recruiting Ruxolitinib for Steroid-refractory GVHD
Condition: Graft Vs Host Disease
Intervention: Drug: Ruxolitinib Oral Tablet
8 Terminated Phase I Trial of LDE225 for Steroid-refractory Chronic GVHD After Allogeneic HSCT
Condition: Graft Versus Host Disease
Intervention: Drug: LDE225
9 Completed Efficacy and Safety of Adult Human Mesenchymal Stem Cells to Treat Steroid Refractory Acute Graft Versus Host Disease
Condition: Graft Versus Host Disease
Interventions: Biological: Mesenchymal Stem Cells;   Biological: placebo
10 Unknown  Donor Regulatory T Cells Infusion in Patients With Chronic Graft-versus-host Disease (GVHD)
Conditions: Chronic Graft-Versus-Host Disease;   Acute Graft-Versus-Host Disease;   Steroid Refractory Graft-Versus-Host Disease
Interventions: Drug: Rapamycin;   Other: T regulatory cells
11 Completed Anti Cytokine Combination Therapy With Daclizumab and Infliximab for Treatment of Steroid Refractory Acute GVHD
Condition: Graft vs Host Disease
Intervention: Drug: daclizumab, infliximab
12 Completed Rituximab Therapy for Steroid-Refractory Chronic Graft Versus Host Disease
Condition: Graft vs Host Disease
Intervention: Drug: Rituximab
13 Terminated Phase I/II Trial rHuKFG for the Treatment of Steroid Refractory Gastrointestinal Acute GVHD
Condition: Acute Graft Versus Host Disease
Intervention: Drug: Recombinant Human Keratinocyte Growth Factor
14 Recruiting Trial of Regulatory T-cells Plus Low-Dose Interleukin-2 for Steroid-Refractory Chronic Graft-versus-Host-Disease
Conditions: Chronic Graft Versus Host Disease;   Chronic GVHD;   Complications of Organ Transplant Stem Cells
Interventions: Other: Treg-enriched infusion;   Drug: Interleukin-2
15 Recruiting A Study of Ruxolitinib in Combination With Corticosteroids for the Treatment of Steroid-Refractory Acute Graft-Versus-Host Disease (REACH1)
Condition: Graft-versus-host Disease
Interventions: Drug: Ruxolitinib;   Drug: Prednisone or methylprednisolone
16 Suspended Biomarkers in Acute Graft-Versus-Host Disease and Extracorporeal Photopheresis Added to Investigator Chosen Therapies of Steroid Refractory Acute GVHD
Conditions: Chronic Graft vs. Host Disease;   Graft vs Host Disease;   Graft-Versus-Host Disease
Interventions: Procedure: Extracorporeal Photopheresis (ECP);   Drug: Methoxsalen
17 Terminated Tocilizumab for Treatment of Steroid Refractory Acute Graft-versus-Host Disease
Condition: Acute Graft Versus Host Disease
Intervention: Drug: Tocilizumab
18 Completed Sirolimus as Treatment of Steroid-Refractory or Steroid-Dependent Chronic Graft-Versus-Host Disease
Conditions: Graft vs Host Disease;   Blood and Marrow Transplant (BMT)
Interventions: Drug: Sirolimus;   Drug: Prednisone
19 Terminated
Has Results
Alefacept in Subjects With Steroid-Refractory Chronic Graft-versus-Host Disease
Condition: Chronic Graft-versus-host Disease
Intervention: Drug: Alefacept
20 Recruiting A Phase 1/2 Trial of Donor Regulatory T-cells for Steroid-Refractory Chronic Graft-versus-Host-Disease
Condition: Graft vs Host Disease
Intervention: Biological: Donor regulatory T cell adoptive immunotherapy in chronic graft versus host disease

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Study has passed its completion date and status has not been verified in more than two years.