451 studies found for:    "gene therapy" OR "gene transfer" OR "virus delivery" | Closed Studies
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Rank Status Study
1 Active, not recruiting EndocardialVascularEndothelialGrowth Factor D(VEGF-D)Gene Therapy for the Treatment of Severe Coronary Heart Disease
Conditions: Angina Pectoris;   Myocardial Infarction
Intervention: Biological: VEGF-D gene transfer
2 Completed Gene Transfer Therapy for Treating Children and Adults With Limb Girdle Muscular Dystrophy Type 2D (LGMD2D)
Condition: Muscular Dystrophies
Interventions: Genetic: rAAV1.tMCK.human-alpha-sarcoglycan- First cohort;   Genetic: Genetic: rAAV1.tMCK.human-alpha-sarcoglycan- Second cohort
3 Active, not recruiting Gene Therapy for X-linked Severe Combined Immunodeficiency
Condition: X-linked Severe Combined Immunodeficiency
Intervention: Other: Gene transfer
4 Completed Gene Therapy for ADA-SCID
Condition: Severe Combined Immunodeficiency Syndrome
Intervention: Genetic: gene transduced PBL and/or gene transduced HSC
5 Completed Follow-up of Breast Cancer and Multiple Myeloma Patients Previously Enrolled in NIH Gene Therapy Studies
Condition: Gene Transfer
Intervention:
6 Completed Gene Therapy of Pancreatic Ductal Adenocarcinoma
Condition: Pancreatic Adenocarcinoma
Intervention: Genetic: Gene Therapy product CYL-02 = plasmid DNA pre-complexed to linear polyethylenimine encoding sst2 + dck::umk genes
7 Suspended Lentiviral Gene Transfer for Treatment of Children Older Than Two Years of Age With X-Linked Severe Combined Immunodeficiency (XSCID)
Conditions: X-linked Severe Combined Immunodeficiency;   XSCID;   SCID-X1;   Gamma C-Deficient SCID
Interventions: Other: Gene-modified CD34+ Hematopoietic stem cells;   Drug: Busulfan
8 Active, not recruiting ADA Gene Transfer Into Hematopoietic Stem/Progenitor Cells for the Treatment of ADA-SCID
Condition: Immunologic Deficiency Syndromes
Intervention: Genetic: Gene transduced CD34+ cells
9 Withdrawn Quality of Life and Neuropsychiatric Sequelae in Patients Treated With Gene Therapy for ADA-SCID and in Their Parents
Condition: ADA-SCID
Intervention:
10 Active, not recruiting Gene Therapy for Wiskott-Aldrich Syndrome
Condition: Wiskott-Aldrich Syndrome
Intervention: Genetic: Autologous CD34 positive cells transduced with WAS encoding lentiviral vector.
11 Completed Intrapleural Gene Transfer for Pleural Mesothelioma
Condition: Malignant Pleural Mesothelioma
Intervention: Biological: SCH 721015
12 Completed Liver Transplantation With ADV-TK Gene Therapy Improves Survival in Patients With Advanced Hepatocellular Carcinoma
Conditions: Hepatocellular Carcinoma;   Liver Transplantation
Intervention: Genetic: ADV-TK (adenovirus-thymidine kinase enzyme) gene therapy
13 Completed Bone Marrow Cell Gene Transfer in Individuals With Fanconi Anemia
Condition: Fanconi Anemia
Intervention: Genetic: Retrovirus Construct
14 Completed Gene Therapy ADA Deficiency
Condition: Adenosine Deaminase Deficiency
Intervention: Biological: Intravenous infusion of transduced cells
15 Completed Clinical Study of AAV1-gamma-sarcoglycan Gene Therapy for Limb Girdle Muscular Dystrophy Type 2C
Conditions: Limb Girdle Muscular Dystrophy Type 2C;   Gamma-sarcoglycanopathy
Intervention: Biological: AAV1-gamma-sarcoglycan vector injection
16 Completed Gene Therapy for Chronic Granulomatous Diseases - Long-term Follow-up
Conditions: Chronic Granulomatous Disease;   Communicable Disease
Interventions: Drug: Gene Therapy Method for CGD;   Device: Isolex 300i Magnetic Cell Selector
17 Enrolling by invitation Clinical Intramuscular Gene Transfer of rAAV1.CMV.huFollistatin344 Trial to Patients With Duchenne Muscular Dystrophy
Condition: Duchenne Muscular Dystrophy
Intervention: Biological: rAAV1.CMV.huFollistin344
18 Active, not recruiting Safety Study of a Gene Transfer Vector for Children With Late Infantile Neuronal Ceroid Lipofuscinosis
Conditions: Batten Disease;   Late Infantile Neuronal Ceroid Lipofuscinosis
Intervention: Genetic: AAV2CUhCLN2
19 Active, not recruiting Gene Therapy for Metachromatic Leukodystrophy
Condition: Metachromatic Leukodystrophy
Intervention: Genetic: Autologous CD34+ stem cells transduced with ARSA encoding lentiviral vector
20 Active, not recruiting Gene Therapy for X-linked Severe Combined Immunodeficiency (SCID-X1)
Condition: X-linked Severe Combined Immunodeficiency
Intervention: Genetic: Single infusion of autologous CD34+ cells transduced with the self-inactivating (SIN) gammaretroviral vector pSRS11.EFS.IL2RG.pre

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Study has passed its completion date and status has not been verified in more than two years.